Ausgabe 1/2022
Inhalt (406 Artikel)
Sildenafil for treating patients with COVID-19 and perfusion mismatch: a pilot randomized trial
Mario G. Santamarina, Ignacio Beddings, Felipe Martinez Lomakin, Dominique Boisier Riscal, Mónica Gutiérrez Claveria, Jaime Vidal Marambio, Nicole Retamal Báez, Cristian Pavez Novoa, César Reyes Allende, Paulina Ferreira Perey, Miguel Gutiérrez Torres, Camila Villalobos Mazza, Constanza Vergara Sagredo, Sebastian Ahumada Bermejo, Eduardo Labarca Mellado, Elizabeth Barthel Munchmeyer, Solange Marchant Ramos, Mariano Volpacchio, Jorge Vega
Mechanical power in pediatric acute respiratory distress syndrome: a PARDIE study
Anoopindar K. Bhalla, Margaret J. Klein, Vicent Modesto I Alapont, Guillaume Emeriaud, Martin C. J. Kneyber, Alberto Medina, Pablo Cruces, Franco Diaz, Muneyuki Takeuchi, Aline B. Maddux, Peter M. Mourani, Cristina Camilo, Benjamin R. White, Nadir Yehya, John Pappachan, Matteo Di Nardo, Steven Shein, Christopher Newth, Robinder Khemani, Rossana Poterala, Analia Fernandez, Antonio Avila Vera, Nilda Agueda Vidal, Deheza Rosemary, Gonzalo Turon, Cecilia Monjes, Alejandro Siaba Serrate, Thomas Iolster, Silvio Torres, Pablo Castellani, Martin Giampieri, Claudia Pedraza, Luis Martin Landry, Maria Althabe, Yanina Vanesa Fortini, Simon Erickson, Samantha Barr, Sara Shea, Warwick Butt, Carmel Delzoppo, Alyssa Pintimalla, Alejandro Fabio Martinez Leon, Gustavo Alfredo Guzman Rivera, Philippe Jouvet, Guillaume Emeriaud, Mariana Dumitrascu, Mary Ellen French, Daniel Caro I, Carlos Acuna, Franco Diaz, Maria Jose Nunez, Yang Chen, Yurika Paola Lopez Alarcon, Ledys Maria Izquierdo, Byron Enrique Piñeres Olave, Pablo Vasquez Hoyos, Pierre Bourgoin, Florent Baudin, George Briassoulis, Stavroula Ilia, Matteo Di Nardo, Fabrizio Chiusolo, Nobuaki Shime, Shinichiro Ohshimo, Yoshiko Kida, Michihito Kyo, Swee Fong Tang, Chian Wern Tai, Lucy Chai See Lum, Ismail Elghuwael, Carlos Gil Escobar, Marta Sousa Moniz, Cristina Camilo, Tarek Hazwani, Nedaa Aldairi, Ahmed Al Amoudi, Ahmad Alahmadti, Yolanda Lopez Fernandez, Juan Ramon Valle, Lidia Martinez, Javier Pilar Orive, Vicent Modesto I Alapont, Marti Pons Odena, Alberto Medina, Susana Reyes Dominguez, Oguz Dursun, Ebru Atike Ongun, Fulya Kamit Can, Ayse Berna Anil, Jon Lillie, Shane Tibby, Paul Wellman, Holly Belfield, Joe Brierley, Troy E. Dominguez, Eugenia Abaleke, Yael Feinstein, James Weitz, Peter-Marc Fortune, Gayathri Subramanian, Claire Jennings, David Inwald, Calandra Feather, Rachel Agbeko, Angela Lawton-Woodhall, Karen McIntyre, Ryan Nofziger, Samir Latifi, Heather Anthony, Ron Sanders, Glenda Hefley, Manpreet Virk, Nancy Jaimon, Robinder Khemani, Christopher Newth, Anoopindar Bhalla, Jeni Kwok, Rica Morzov, Sidharth Mahapatra, Edward Truemper, Lucinda Kustka, Sholeen T. Nett, Marcy Singleton, J. Dean Jarvis, Nadir Yehya, Natalie Napolitano, Marie Murphy, Laurie Ronan, Ryan Morgan, Sherri Kubis, Elizabeth Broden, Rainer Gedeit, Kathy Murkowski, Katherine Woods, Mary Kasch, Yong Y. Han, Jeremy T. Affolter, Kelly S. Tieves, Amber Hughes-Schalk, Ranjit S. Chima, Kelli Krallman, Erin Stoneman, Laura Benken, Toni Yunger, James Schneider, Todd Sweberg, Aaron Kessel, Christopher L. Carroll, James Santanelli, Kate G. Ackerman, Melissa Cullimore, Courtney Rowan, Melissa Bales, W. Keith Dockery, Shirin Jafari-Namin, Dana Barry, Keary Jane’t, Shira Gertz, Bria Coates, Lawren Wellisch, Kiona Allen, Avani Shukla, Neal J. Thomas, Debbie Spear, Steven L. Shein, Margaret M. Parker, Daniel Sloniewsky, Christine Allen, Amy Harrell, Natalie Cvijanovich, Katri Typpo, Connor Kelley, Caroline King, Anil Sapru, Anna Ratiu, Neda Ashtari, Asumthia S. Jeyapalan, Alvaro Coronado-Munoz, Janet Hume, Dan Nerheim, Lincoln Smith, Silvia Hartmann, Erin Sullivan, Courtney Merritt, Awni Al-Subu, Andrea Blom, Deyin D. Hsing, Steve Pon, Jim Brian Estil, Richa Gautam, John S. Giuliano Jr, Joana Tala
Vitamin C for ≥ 5 days is associated with decreased hospital mortality in sepsis subgroups: a nationwide cohort study
Sun-Young Jung, Min-Taek Lee, Moon Seong Baek, Won-Young Kim
Hyperoxemia in postsurgical sepsis/septic shock patients is associated with reduced mortality
Marta Martín-Fernández, María Heredia-Rodríguez, Irene González-Jiménez, Mario Lorenzo-López, Estefanía Gómez-Pesquera, Rodrigo Poves-Álvarez, F. Javier Álvarez, Pablo Jorge-Monjas, Juan Beltrán-DeHeredia, Eduardo Gutiérrez-Abejón, Francisco Herrera-Gómez, Gabriella Guzzo, Esther Gómez-Sánchez, Álvaro Tamayo-Velasco, Rocío Aller, Paolo Pelosi, Jesús Villar, Eduardo Tamayo
Association between unmet medication needs after hospital discharge and readmission or death among acute respiratory failure survivors: the addressing post-intensive care syndrome (APICS-01) multicenter prospective cohort study
Samuel M. Brown, Victor D. Dinglas, Narjes Akhlaghi, Somnath Bose, Valerie Banner-Goodspeed, Sarah Beesley, Danielle Groat, Tom Greene, Ramona O. Hopkins, Mustafa Mir-Kasimov, Carla M. Sevin, Alison E. Turnbull, James C. Jackson, Dale M. Needham, Elise Caraker, Sai Phani Sree Cherukuri, Naga Preethi Kadiri, Tejaswi Kalva, Mounica Koneru, Pooja Kota, Emma Maelian Lee, Mazin Ali Mahmoud, Albahi Malik, Roozbeh Nikooie, Darin Roberts, Sriharsha Singu, Parvaneh Vaziri, Katie Brown, Austin Daw, Mardee Merrill, Rilee Smith, Ellie Hirshberg, Jorie Butler, Benjamin Hoenig, Maria Karamourtopoulos, Margaret Hays, Rebecca Abel, Craig High, Emily Beck, Brent Armbruster, Darrin Applegate, Melissa Fergus, Naresh Kumar, Megan Roth, Susan Mogan, Rebecca Abel, Andrea De Souza Licht, Isabel Londono, Julia Larson, Krystal Capers, Maria Karamourtopoulos, Benjamin Hoenig, Andrew Toksoz-Exley, Julia Crane
Gut microbiota plays a pivotal role in opioid-induced adverse effects in gastrointestinal system
Rongpeng Xu, Liying Miao, Chun Yang, Bin Zhu
Protein intake and outcome of critically ill patients: analysis of a large international database using piece-wise exponential additive mixed models
Wolfgang H. Hartl, Philipp Kopper, Andreas Bender, Fabian Scheipl, Andrew G. Day, Gunnar Elke, Helmut Küchenhoff
Prone positioning during venovenous extracorporeal membrane oxygenation for acute respiratory distress syndrome: a pooled individual patient data analysis
Marco Giani, Emanuele Rezoagli, Christophe Guervilly, Jonathan Rilinger, Thibault Duburcq, Matthieu Petit, Laura Textoris, Bruno Garcia, Tobias Wengenmayer, Giacomo Grasselli, Antonio Pesenti, Alain Combes, Giuseppe Foti, Matthieu Schmidt, Giacomo Bellani, Gennaro Martucci, Antonio Arcadipane, Alberto Lucchini, Eugenio Garofalo, Mirko Belliato, Vito Fanelli, Laurent Papazian, Jean-Marie Forel, Sami Hraiech, Antoine Roch, Eloi Prud’homme, Charles Edouard Luyt, Guillaume Hekimian, Juliette Chommeloux, Marc Pineton de Chambrun, Nicolas Brechot, Dawid L. Staudacher, Alexander Supady, Paul Biever, Viviane Zotzmann, Xavier Bemtgen, Asieb Sekandarzad, Kirsten Krüger, Annabelle Flügler, Erika Parmentier-Decrucq, Julien Poissy, Alexandre Gaudet, Mouhamed D. Moussa, André Vincentelli
Early, biomarker-guided steroid dosing in COVID-19 Pneumonia: a pilot randomized controlled trial
Yewande E. Odeyemi, Sarah J. Chalmers, Erin F. Barreto, Jacob C. Jentzer, Ognjen Gajic, Hemang Yadav
Persistence of live virus in critically ill patients infected with SARS-COV-2: a prospective observational study
Duane J. Funk, Jared Bullard, Sylvan Lother, Gloria Vazquez Grande, Lauren Garnett, Kaylie Doan, Kerry Dust, Anand Kumar, Guillaume Poliquin, Jim Strong
Invasive pulmonary aspergillosis among intubated patients with SARS-CoV-2 or influenza pneumonia: a European multicenter comparative cohort study
Anahita Rouzé, Elise Lemaitre, Ignacio Martin-Loeches, Pedro Povoa, Emili Diaz, Rémy Nyga, Antoni Torres, Matthieu Metzelard, Damien Du Cheyron, Fabien Lambiotte, Fabienne Tamion, Marie Labruyere, Claire Boulle Geronimi, Charles-Edouard Luyt, Martine Nyunga, Olivier Pouly, Arnaud W. Thille, Bruno Megarbane, Anastasia Saade, Eleni Magira, Jean-François Llitjos, Iliana Ioannidou, Alexandre Pierre, Jean Reignier, Denis Garot, Louis Kreitmann, Jean-Luc Baudel, Guillaume Voiriot, Gaëtan Plantefeve, Elise Morawiec, Pierre Asfar, Alexandre Boyer, Armand Mekontso-Dessap, Demosthenes Makris, Christophe Vinsonneau, Pierre-Edouard Floch, Clémence Marois, Adrian Ceccato, Antonio Artigas, Alexandre Gaudet, David Nora, Marjorie Cornu, Alain Duhamel, Julien Labreuche, Saad Nseir, Mathilde Bouchereau, Boualem Sendid, Sean Boyd, Luis Coelho, Julien Maizel, Pierre Cuchet, Wafa Zarrougui, Déborah Boyer, Jean-Pierre Quenot, Mehdi Imouloudene, Marc Pineton de Chambrun, Thierry Van Der Linden, François Arrive, Sebastian Voicu, Elie Azoulay, Edgard Moglia, Frédéric Pene, Catia Cilloniz, Didier Thevenin, Charlotte Larrat, Laurent Argaud, Bertrand Guidet, Matthieu Turpin, Damien Contou, Alexandra Beurton, Julien Demiselle, David Meguerditchian, Keyvan Razazi, Romain Arrestier, Vassiliki Tsolaki, Mehdi Marzouk, Guillaume Brunin, Nicolas Weiss, Luis Morales
Respiratory effects of lung recruitment maneuvers depend on the recruitment-to-inflation ratio in patients with COVID-19-related acute respiratory distress syndrome
Yoann Zerbib, Alexis Lambour, Julien Maizel, Loay Kontar, Bertrand De Cagny, Thierry Soupison, Thomas Bradier, Michel Slama, Clément Brault
Elevated plasma Galectin-3 is associated with major adverse kidney events and death after ICU admission
L. Boutin, M. Legrand, M. Sadoune, A. Mebazaa, E. Gayat, C. E. Chadjichristos, F. Dépret
Biomarkers for sepsis: more than just fever and leukocytosis—a narrative review
Tatiana Barichello, Jaqueline S. Generoso, Mervyn Singer, Felipe Dal-Pizzol
Comparison between meropenem and ceftolozane/tazobactam: possible influence of CRRT
Patrick M. Honore, Sebastien Redant, Thierry Preseau, Sofie Moorthamers, Keitiane Kaefer, Leonel Barreto Gutierrez, Rachid Attou, Andrea Gallerani, Willem Boer, David De Bels
Impact of exposure time in awake prone positioning on clinical outcomes of patients with COVID-19-related acute respiratory failure treated with high-flow nasal oxygen: a multicenter cohort study
Mariano Esperatti, Marina Busico, Nora Angélica Fuentes, Adrian Gallardo, Javier Osatnik, Alejandra Vitali, Elizabeth Gisele Wasinger, Matías Olmos, Jorgelina Quintana, Santiago Nicolas Saavedra, Ana Inés Lagazio, Facundo Juan Andrada, Hiromi Kakisu, Nahuel Esteban Romano, Agustin Matarrese, Mariela Adriana Mogadouro, Giuliana Mast, Claudia Navarro Moreno, Greta Dennise Rebaza Niquin, Veronica Barbaresi, Alejandro Bruhn Cruz, Bruno Leonel Ferreyro, Antoni Torres, Anabel Miranda Tirado, María Constanza Viñas, Juan Manuel Pintos, Maria Eugenia Gonzalez, Maite Mateos, Mariela Marisol Laiz, Jose Garcia Urrutia, Micaela Ruiz Seifert, Emilce Mastroberti
Choosing the right reference cohort for assessing outcome of venovenous ECMO
Alexander Supady, Paul M. Biever, Dawid L. Staudacher, Tobias Wengenmayer
Impact of time to intubation on mortality and pulmonary sequelae in critically ill patients with COVID-19: a prospective cohort study
Jessica González, Iván D. Benítez, David de Gonzalo-Calvo, Gerard Torres, Jordi de Batlle, Silvia Gómez, Anna Moncusí-Moix, Paola Carmona, Sally Santisteve, Aida Monge, Clara Gort-Paniello, María Zuil, Ramón Cabo-Gambín, Carlos Manzano Senra, José Javier Vengoechea Aragoncillo, Rafaela Vaca, Olga Minguez, María Aguilar, Ricard Ferrer, Adrián Ceccato, Laia Fernández, Ana Motos, Jordi Riera, Rosario Menéndez, Darío Garcia-Gasulla, Oscar Peñuelas, Gonzalo Labarca, Jesús Caballero, Carme Barberà, Antoni Torres, Ferran Barbé, Ricard Ferrer, Adrián Cecato, Laia Fernández, Anna Motos, Jordi Riera, Rosario Menéndez, Dario García-Gasulla, Oscar Peñuelas, Gonzalo Labarca, Jesus Caballero, Carme Barberà
Time-to-antibiotics and clinical outcomes in patients with sepsis and septic shock: a prospective nationwide multicenter cohort study
Yunjoo Im, Danbee Kang, Ryoung-Eun Ko, Yeon Joo Lee, Sung Yoon Lim, Sunghoon Park, Soo Jin Na, Chi Ryang Chung, Mi Hyeon Park, Dong Kyu Oh, Chae-Man Lim, Gee Young Suh, Chae-Man Lim, Sang-Bum Hong, Dong Kyu Oh, Gee Young Suh, Kyeongman Jeon, Ryoung-Eun Ko, Young-Jae Cho, Yeon Joo Lee, Sung Yoon Lim, Sunghoon Park, Jeongwon Heo, Jae-myeong Lee, Kyung Chan Kim, Yeon Joo Lee, Youjin Chang, Kyeongman Jeon, Sang-Min Lee, Chae-Man Lim, Suk-Kyung Hong, Woo Hyun Cho, Sang Hyun Kwak, Heung Bum Lee, Jong-Joon Ahn, Gil Myeong Seong, Song-I. Lee, Sunghoon Park, Tai Sun Park, Su Hwan Lee, Eun Young Choi, Jae Young Moon
Value of variation of end-tidal carbon dioxide for predicting fluid responsiveness during the passive leg raising test in patients with mechanical ventilation: a systematic review and meta-analysis
Haijun Huang, Chenxia Wu, Qinkang Shen, Yixin Fang, Hua Xu
The prognostic utility of protein C as a biomarker for adult sepsis: a systematic review and meta-analysis
Vanessa Catenacci, Fatima Sheikh, Kush Patel, Alison E. Fox-Robichaud
Correction to: Vital-sign circadian rhythms in patients prior to discharge from an ICU: a retrospective observational analysis of routinely recorded physiological data
Shaun Davidson, Mauricio Villarroel, Mirae Harford, Eoin Finnegan, Joao Jorge, Duncan Young, Peter Watkinson, Lionel Tarassenko
Omega-6 sparing effects of parenteral lipid emulsions—an updated systematic review and meta-analysis on clinical outcomes in critically ill patients
Quirin Notz, Zheng-Yii Lee, Johannes Menger, Gunnar Elke, Aileen Hill, Peter Kranke, Daniel Roeder, Christopher Lotz, Patrick Meybohm, Daren K. Heyland, Christian Stoppe
Association between hospital and ICU structural factors and patient outcomes in China: a secondary analysis of the National Clinical Improvement System Data in 2019
Zhen Li, Xudong Ma, Sifa Gao, Qi Li, Hongbo Luo, Jianhua Sun, Wei Du, Longxiang Su, Lu Wang, Qing Zhang, Zunzhu Li, Xiang Zhou, Dawei Liu, Xue Wang, Xiangdong Guan, Yan Kang, Bin Xiong, Bingyu Qin, Kejian Qian, Chunting Wang, Mingyan Zhao, Xiaochun Ma, Xiangyou Yu, Jiandong Lin, Aijun Pan, Haibo Qiu, Feng Shen, Shusheng Li, Yuhang Ai, Xiaohong Xie, Jing Yan, Weidong Wu, Meili Duan, Linjun Wan, Xiaojun Yang, Jian Liu, Hang Xu, Dongpo Jiang, Lei Xu, Zhuang Chen, Guoying Lin, Zhengping Yang, Zhenjie Hu
Vitamin C improves microvascular reactivity and peripheral tissue perfusion in septic shock patients
Jean-Rémi Lavillegrand, Lisa Raia, Tomas Urbina, Geoffroy Hariri, Paul Gabarre, Vincent Bonny, Naïke Bigé, Jean-Luc Baudel, Arnaud Bruneel, Thierry Dupre, Bertrand Guidet, Eric Maury, Hafid Ait-Oufella
Intravenous vitamin C administration to patients with septic shock: a pilot randomised controlled trial
Patrice Rosengrave, Emma Spencer, Jonathan Williman, Jan Mehrtens, Stacey Morgan, Tara Doyle, Kymbalee Van Der Heyden, Anna Morris, Geoff Shaw, Anitra C. Carr
Severe necrotizing soft-tissue infection-associated mortality: Have a look at the computed tomography!
Sébastien Tanaka, Michael Thy, Ralph Khoury, Alexy Tran-Dinh, Antoine Khalil, Philippe Montravers
Effects of prone and lateral positioning alternate in high-flow nasal cannula patients with severe COVID-19
Yang Chong, Chuanchuan Nan, Wenjing Mu, Changsong Wang, Mingyan Zhao, Kaijiang Yu
Immune effects of PI3K/Akt/HIF-1α-regulated glycolysis in polymorphonuclear neutrophils during sepsis
Tingting Pan, Shaoqiong Sun, Yang Chen, Rui Tian, Erzhen Chen, Ruoming Tan, Xiaoli Wang, Zhaojun Liu, Jialin Liu, Hongping Qu
Corticosteroids as risk factor for COVID-19-associated pulmonary aspergillosis in intensive care patients
Rasmus Leistner, Lisa Schroeter, Thomas Adam, Denis Poddubnyy, Miriam Stegemann, Britta Siegmund, Friederike Maechler, Christine Geffers, Frank Schwab, Petra Gastmeier, Sascha Treskatsch, Stefan Angermair, Thomas Schneider
Effects of positive end-expiratory pressure on lung ultrasound patterns and their correlation with intracranial pressure in mechanically ventilated brain injured patients
Chiara Robba, Lorenzo Ball, Denise Battaglini, Francesca Iannuzzi, Iole Brunetti, Pietro Fiaschi, Gianluigi Zona, Fabio Silvio Taccone, Antonio Messina, Silvia Mongodi, Paolo Pelosi
Timing of inspiratory muscle activity detected from airway pressure and flow during pressure support ventilation: the waveform method
Francesco Mojoli, Marco Pozzi, Anita Orlando, Isabella M. Bianchi, Eric Arisi, Giorgio A. Iotti, Antonio Braschi, Laurent Brochard
Endotheliopathy is associated with slower liberation from mechanical ventilation: a cohort study
Martin Schønemann-Lund, Theis S. Itenov, Johan E. Larsson, Birgitte Lindegaard, Pär I. Johansson, Morten H. Bestle
Extracorporeal membrane oxygenation for COVID-19 and influenza H1N1 associated acute respiratory distress syndrome: a multicenter retrospective cohort study
Vito Fanelli, Marco Giani, Giacomo Grasselli, Francesco Mojoli, Gennaro Martucci, Lorenzo Grazioli, Francesco Alessandri, Silvia Mongodi, Gabriele Sales, Giorgia Montrucchio, Costanza Pizzi, Lorenzo Richiardi, Luca Lorini, Antonio Arcadipane, Antonio Pesenti, Giuseppe Foti, Nicolò Patroniti, Luca Brazzi, VMarco Ranieri
Detection of cerebral hypoperfusion with a dynamic hyperoxia test using brain oxygenation pressure monitoring
Thomas Gargadennec, Gioconda Ferraro, Rudy Chapusette, Xavier Chapalain, Elisa Bogossian, Morgane Van Wettere, Lorenzo Peluso, Jacques Creteur, Olivier Huet, Niloufar Sadeghi, Fabio Silvio Taccone
Multidimensional analysis of the host response reveals prognostic and pathogen-driven immune subtypes among adults with sepsis in Uganda
Matthew J. Cummings, Barnabas Bakamutumaho, Adam Price, Nicholas Owor, John Kayiwa, Joyce Namulondo, Timothy Byaruhanga, Moses Muwanga, Christopher Nsereko, Stephen Sameroff, Rafal Tokarz, Wai Wong, Shivang S. Shah, Michelle H. Larsen, W. Ian Lipkin, Julius J. Lutwama, Max R. O’Donnell
Non-invasive oxygenation support in acutely hypoxemic COVID-19 patients admitted to the ICU: a multicenter observational retrospective study
Pedro David Wendel-Garcia, Arantxa Mas, Cristina González-Isern, Ricard Ferrer, Rafael Máñez, Joan-Ramon Masclans, Elena Sandoval, Paula Vera, Josep Trenado, Rafael Fernández, Josep-Maria Sirvent, Melcior Martínez, Mercedes Ibarz, Pau Garro, José Luis Lopera, María Bodí, Joan Carles Yébenes-Reyes, Carles Triginer, Imma Vallverdú, Anna Baró, Fernanda Bodí, Paula Saludes, Mauricio Valencia, Ferran Roche-Campo, Arturo Huerta, Francisco José Cambra, Carme Barberà, Jorge Echevarria, Óscar Peñuelas, Jordi Mancebo, R. Ferrer, O. Roca, X. Nuvials, J. C. Ruiz, E. Papiol, R. Máñez, V. D. Gumicio, E. Sandoval, G. Muñoz, D. Toapanta, P. Castro, J. Osorio, J. R. Masclans, R. Muñoz-Bermúdez, F. Parrilla, P. Pérez-Teran, J. Marin-Corral, A. Mas, B. Cancio, S. Hernández-Marín, M. R. Koborzan, C. A. Briones, J. Trenado, R. Fernández, J. M. Sirvent, P. Sebastian, X. Saiz, M. Martínez, M. Ibarz, P. Garro, C. Pedrós, E. Vendrell, J. L. Lopera, M. Bodí, A. Rodríguez, G. Moreno, J. C. Yébenes-Reyes, C. Triginer, I. Vallverdú, A. Baró, M. Morales, F. Bodí, P. Saludes, J.-R. Cervelló, M. Valencia, F. Roche-Campo, D. Franch-Llasat, A. Huerta, P. Santigosa, F. J. Cambra, S. Benito, C. Barberà, J. Echevarría, J. Mancebo, P. Vera, J.-A. Santos, J. Baldirà, A.-J. Betbesé, M. Izura, I. Morán, J.-C. Suárez, L. Zapata, N. Rodríguez, M. Torrens, A. Cordón, C. Gomila, M. Flores, A. Segarra, M. Morales, L. Mateo, M. Martos, C. González-Isern
The physiological foundations of critical care medicine: the contribution of Joseph Milic-Emili, a physiologist “by hook or by crook”
V. Marco Ranieri, Claude Guérin
Prone position during venovenous extracorporeal membrane oxygenation: survival analysis needed for a time-dependent intervention
Akram M. Zaaqoq, Adrian G. Barnett, Silver Heinsar, Matthew J. Griffee, Graeme MacLaren, Jeffrey P. Jacobs, Jacky Y. Suen, Gianluigi Li Bassi, John F. Fraser, Heidi J. Dalton, Giles J. Peek
Tracheostomy timing and clinical outcomes in ventilated COVID-19 patients: a systematic review and meta-analysis
Yun Ji, Yumin Fang, Baoli Cheng, Libin Li, Xiangming Fang
Study find that COVID ARDS was associated with a low risk for possible or proven PCP: still true after dexamethasone use
Patrick M. Honore, Sebastien Redant, Thierry Preseau, Keitiane Kaefer, Leonel Barreto Gutierrez, Sami Anane, Rachid Attou, Andrea Gallerani, David De Bels
Correction to: Association between hospital and ICU structural factors and patient outcomes in China: a secondary analysis of the National Clinical Improvement System Data in 2019
Zhen Li, Xudong Ma, Sifa Gao, Qi Li, Hongbo Luo, Jianhua Sun, Wei Du, Longxiang Su, Lu Wang, Qing Zhang, Zunzhu Li, Xiang Zhou, Dawei Liu, Xue Wang, Xiangdong Guan, Yan Kang, Bin Xiong, Bingyu Qin, Kejian Qian, Chunting Wang, Mingyan Zhao, Xiaochun Ma, Xiangyou Yu, Jiandong Lin, Aijun Pan, Haibo Qiu, Feng Shen, Shusheng Li, Yuhang Ai, Xiaohong Xie, Jing Yan, Weidong Wu, Meili Duan, Linjun Wan, Xiaojun Yang, Jian Liu, Hang Xu, Dongpo Jiang, Lei Xu, Zhuang Chen, Guoying Lin, Zhengping Yang, Zhenjie Hu
Relationship between time of emergency department admission and adherence to the Surviving Sepsis Campaign bundle in patients with septic shock
Je Sung You, Yoo Seok Park, Sung Phil Chung, Hye Sun Lee, Soyoung Jeon, Won Young Kim, Tae Gun Shin, You Hwan Jo, Gu Hyun Kang, Sung Hyuk Choi, Gil Joon Suh, Byuk Sung Ko, Kap Su Han, Jong Hwan Shin, Taeyoung Kong, Won Young Kim, Seung Mok Ryoo, Tae Gun Shin, Sung Yeon Hwang, You Hwan Jo, Sung Phil Chung, Yoon Jung Hwang, Jin Ho Beom, Yoo Seok Park, Gu Hyun Kang, Sung-Hyuk Choi, Young-Hoon Yoon, Gil Joon Suh, Tae Ho Lim, Byuk Sung Ko, Kap Su Han, Jong Hwan Shin, Hui Jai Lee, Kyoung Min You
Timing of intubation, beds in intensive care and inter-hospital transfer: rings of a complex chain during pandemic conditions
Filippo Sanfilippo, Luigi La Via, Giuseppe Carpinteri, Marinella Astuto
Actively implementing an evidence-based feeding guideline for critically ill patients (NEED): a multicenter, cluster-randomized, controlled trial
Lu Ke, Jiajia Lin, Gordon S. Doig, Arthur R. H. van Zanten, Yang Wang, Juan Xing, Zhongheng Zhang, Tao Chen, Lixin Zhou, Dongpo Jiang, Qindong Shi, Jiandong Lin, Jun Liu, Aibin Cheng, Yafeng Liang, Peiyang Gao, Junli Sun, Wenming Liu, Zhenyu Yang, Rumin Zhang, Wei Xing, An Zhang, Zhigang Zhou, Tingfa Zhou, Yang Liu, Fei Tong, Qiuhui Wang, Aijun Pan, Xiaobo Huang, Chuming Fan, Weihua Lu, Dongwu Shi, Lei Wang, Wei Li, Liming Gu, Yingguang Xie, Rongqing Sun, Feng Guo, Lin Han, Lihua Zhou, Xiangde Zheng, Feng Shan, Jianbo Liu, Yuhang Ai, Yan Qu, Liandi Li, Hailing Li, Zhiguo Pan, Donglin Xu, Zhiqiang Zou, Yan Gao, Chunli Yang, Qiuye Kou, Xijing Zhang, Jinglan Wu, Chuanyun Qian, Weixing Zhang, Minjie Zhang, Yuan Zong, Bingyu Qin, Fusen Zhang, Zhe Zhai, Yun Sun, Ping Chang, Bo Yu, Min Yu, Shiying Yuan, Yijun Deng, Liyun Zhao, Bin Zang, Yuanfei Li, Fachun Zhou, Xiaomei Chen, Min Shao, Weidong Wu, Ming Wu, Zhaohui Zhang, Yimin Li, Qiang Guo, Zhiyong Wang, Yuanqi Gong, Yunlin Song, Kejian Qian, Yongjian Feng, Baocai Fu, Xueyan Liu, Zhiping Li, Chuanyong Gong, Cheng Sun, Jian Yu, Zhongzhi Tang, Linxi Huang, Biao Ma, Zhijie He, Qingshan Zhou, Rongguo Yu, Zhihui Tong, Weiqin Li, Lu Ke, Jiajia Lin, Zhihui Tong, Weiqin Li, Yang Wang, Juan Xing, Zhongheng Zhang, Feng Guo, Tao Chen, Lixin Zhou, Dongpo Jiang, Qindong Shi, Jiandong Lin, Jun Liu, Aibin Cheng, Yafeng Liang, Peiyang Gao, Junli Sun, Wenming Liu, Zhenyu Yang, Rumin Zhang, Wei Xing, An Zhang, Zhigang Zhou, Tingfa Zhou, Yang Liu, Fei Tong, Qiuhui Wang, Aijun Pan, Xiaobo Huang, Chuming Fan, Weihua Lu, Dongwu Shi, Lei Wang, Wei Li, Liming Gu, Yingguang Xie, Rongqing Sun, Lin Han, Lihua Zhou, Xiangde Zheng, Feng Shan, Liandi Li, Jianbo Liu, Yuhang Ai, Yan Qu, Hailing Li, Zhiguo Pan, Donglin Xu, Zhiqiang Zou, Yan Gao, Chunli Yang, Qiuye Kou, Xijing Zhang, Jinglan Wu, Chuanyun Qian, Weixing Zhang, Minjie Zhang, Yongjian Feng, Yuan Zong, Bingyu Qin, Fusen Zhang, Zhe Zhai, Yun Sun, Ping Chang, Bo Yu, Min Yu, Shiying Yuan, Yijun Deng, Liyun Zhao, Bin Zang, Yuanfei Li, Fachun Zhou, Xiaomei Chen, Min Shao, Weidong Wu, Ming Wu, Zhaohui Zhang, Yimin Li, Qiang Guo, Zhiyong Wang, Yuanqi Gong, Yunlin Song, Kejian Qian, Baocai Fu, Xueyan Liu, Zhiping Li, Chuanyong Gong, Cheng Sun, Jian Yu, Zhongzhi Tang, Linxi Huang, Biao Ma, Zhijie He, Qingshan Zhou, Rongguo Yu
Repeated endo-tracheal tube disconnection generates pulmonary edema in a model of volume overload: an experimental study
Bhushan H. Katira, Doreen Engelberts, Sheena Bouch, Jordan Fliss, Luca Bastia, Kohei Osada, Kim A. Connelly, Marcelo B. P. Amato, Niall D. Ferguson, Wolfgang M. Kuebler, Brian P. Kavanagh, Laurent J. Brochard, Martin Post
Treatment of COVID-19-associated ARDS with mesenchymal stromal cells: a multicenter randomized double-blind trial
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Dopamine use and its consequences in the intensive care unit: a cohort study utilizing the Japanese Intensive care PAtient Database
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The necessity of a loading dose when prescribing intravenous colistin in critically ill patients with CRGNB-associated pneumonia: a multi-center observational study
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Continuous renal replacement therapy versus intermittent hemodialysis as first modality for renal replacement therapy in severe acute kidney injury: a secondary analysis of AKIKI and IDEAL-ICU studies
Stéphane Gaudry, François Grolleau, Saber Barbar, Laurent Martin-Lefevre, Bertrand Pons, Éric Boulet, Alexandre Boyer, Guillaume Chevrel, Florent Montini, Julien Bohe, Julio Badie, Jean-Philippe Rigaud, Christophe Vinsonneau, Raphaël Porcher, Jean-Pierre Quenot, Didier Dreyfuss
Intensive care-related loss of quality of life and autonomy at 6 months post-discharge: Does COVID-19 really make things worse?
Fabrice Thiolliere, Claire Falandry, Bernard Allaouchiche, Victor Geoffray, Laurent Bitker, Jean Reignier, Paul Abraham, Stephanie Malaquin, Baptiste Balança, Hélène Boyer, Philippe Seguin, Céline Guichon, Marie Simon, Arnaud Friggeri, Charles-Hervé Vacheron, Laurent Argaud, Bernard Floccard, Thomas Rimmele, Albrice Levrat, Stanislas Ledechowski, Remi Bruyere, Carole Schwebel, Benedicte Zerr, Luc Jarrige, Quentin Blanc, Jerome Morel, Olivier Baldesi, Gaëtan Plantefeve, Philippe Seguin, Claire Dahyot-Fizelier, Michel Bonnivard, J. Roustan, S. Vimeux, Ali Mofredj, Sami Alaya, Adel Maamar, Julio Badie, Bertrand Souweine, Gerald Choukroun, Oriane Fontaine, Jean Michel Constantin, Marc Gainier, Benoit Misset, Jean Claude Orban, Jean Reignier, Jean-Marc Doise, Olivier Millet, Laurent Favier, Berangere Jany, Ramin Ravan, Delphine Roux, Pierre Marie Bertrand, Nicolas Bele, Stéphanie Malaquin, Pierre Grégoire Guinot, Jean Pierre Quenot, Fanny Bounes, Claude Koubi, P. Danin
External validation of the 2020 ERC/ESICM prognostication strategy algorithm after cardiac arrest
Chun Song Youn, Kyu Nam Park, Soo Hyun Kim, Byung Kook Lee, Tobias Cronberg, Sang Hoon Oh, Kyung Woon Jeung, In Soo Cho, Seung Pill Choi
Amniotic fluid embolism rescued by venoarterial extracorporeal membrane oxygenation
Sarah Aissi James, Thomas Klein, Guillaume Lebreton, Jacky Nizard, Juliette Chommeloux, Nicolas Bréchot, Marc Pineton de Chambrun, Guillaume Hékimian, Charles-Edouard Luyt, Bruno Levy, Antoine Kimmoun, Alain Combes, Matthieu Schmidt
Extracorporeal membrane oxygenation for severe COVID-19-associated acute respiratory distress syndrome in Poland: a multicenter cohort study
Ewa Trejnowska, Dominik Drobiński, Piotr Knapik, Marta Wajda-Pokrontka, Konstanty Szułdrzyński, Jakub Staromłyński, Wojciech Nowak, Maciej Urlik, Marek Ochman, Waldemar Goździk, Wojciech Serednicki, Jakub Śmiechowicz, Jakub Brączkowski, Wojciech Bąkowski, Anna Kwinta, Michał O. Zembala, Piotr Suwalski
Association between timing of speech and language therapy initiation and outcomes among post-extubation dysphagia patients: a multicenter retrospective cohort study
Takashi Hongo, Ryohei Yamamoto, Keibun Liu, Takahiko Yaguchi, Hisashi Dote, Ryusuke Saito, Tomoyuki Masuyama, Kosuke Nakatsuka, Shinichi Watanabe, Takahiro Kanaya, Tomoya Yamaguchi, Tetsuya Yumoto, Hiromichi Naito, Atsunori Nakao
EXpert consensus On Diaphragm UltraSonography in the critically ill (EXODUS): a Delphi consensus statement on the measurement of diaphragm ultrasound-derived parameters in a critical care setting
Mark E. Haaksma, Jasper M. Smit, Alain Boussuges, Alexandre Demoule, Martin Dres, Giovanni Ferrari, Paolo Formenti, Ewan C. Goligher, Leo Heunks, Endry H. T. Lim, Lidwine B. Mokkink, Eleni Soilemezi, Zhonghua Shi, Michele Umbrello, Luigi Vetrugno, Emmanuel Vivier, Lei Xu, Massimo Zambon, Pieter R. Tuinman
Pancreatic stone protein as a biomarker of sepsis
Diogo Lopes, Beatriz Chumbinho, João Pedro Bandovas, Pedro Faria, Catarina Espírito Santo, Bernardo Ferreira, Luis Val-Flores, Rui Pereira, Nuno Germano, Luís Bento
Auxora vs. placebo for the treatment of patients with severe COVID-19 pneumonia: a randomized-controlled clinical trial
Charles Bruen, Mukhtar Al-Saadi, Edward A. Michelson, Maged Tanios, Raul Mendoza-Ayala, Joseph Miller, Jeffrey Zhang, Kenneth Stauderman, Sudarshan Hebbar, Peter C. Hou
ICU bereaved surrogates’ comorbid psychological-distress states and their associations with prolonged grief disorder
Fur-Hsing Wen, Wen-Chi Chou, Chung-Chi Huang, Tsung-Hui Hu, Ming Chu Chiang, Li-Pang Chuang, Siew Tzuh Tang
A novel Vascular Leak Index identifies sepsis patients with a higher risk for in-hospital death and fluid accumulation
Jay Chandra, Miguel A. Armengol de la Hoz, Gwendolyn Lee, Alexandria Lee, Patrick Thoral, Paul Elbers, Hyung-Chul Lee, John S. Munger, Leo Anthony Celi, David A. Kaufman
Plasma disappearance rate of albumin when infused as a 20% solution
Markus Zdolsek, Patrick Y. Wuethrich, Michaela Gunnström, Joachim H. Zdolsek, Emma Hasselgren, Christian M. Beilstein, Dominique Engel, Robert G. Hahn
Gut bacteriobiota and mycobiota are both associated with Day-28 mortality among critically ill patients
Renaud Prevel, Raphaël Enaud, Arthur Orieux, Adrian Camino, Patrick Berger, Alexandre Boyer, Laurence Delhaes, Didier Gruson
Derivation and performance of an end-of-life practice score aimed at interpreting worldwide treatment-limiting decisions in the critically ill
Spyros D. Mentzelopoulos, Su Chen, Joseph L. Nates, Jacqueline M. Kruser, Christiane Hartog, Andrej Michalsen, Nikolaos Efstathiou, Gavin M. Joynt, Suzana Lobo, Alexander Avidan, Charles L. Sprung, Wesley Ely, Erwin J. O. Kompanje, Mervyn Mer, Charles Feldman, Victoria Metaxa, Myrick C. Shinall, John Myburgh, Charikleia S. Vrettou
Serum IL-17 levels are higher in critically ill patients with AKI and associated with worse outcomes
Jason A. Collett, Victor Ortiz-Soriano, Xilong Li, Alexander H. Flannery, Robert D. Toto, Orson W. Moe, David P. Basile, Javier A. Neyra
Closed-loop oxygen control improves oxygen therapy in acute hypoxemic respiratory failure patients under high flow nasal oxygen: a randomized cross-over study (the HILOOP study)
Oriol Roca, Oriol Caritg, Manel Santafé, Francisco J. Ramos, Andrés Pacheco, Marina García-de-Acilu, Ricard Ferrer, Marcus J. Schultz, Jean-Damien Ricard
High-flow nasal cannula versus conventional oxygen therapy in acute COPD exacerbation with mild hypercapnia: a multicenter randomized controlled trial
Jingen Xia, Sichao Gu, Wei Lei, Jihua Zhang, Hui Wei, Chao Liu, Han Zhang, Rongli Lu, Liqiong Zhang, Mingyan Jiang, Chao Hu, Zhenshun Cheng, Chaojie Wei, Yusheng Chen, Fengfeng Lu, Min Chen, Hong Bi, Hui Liu, Cunzi Yan, Hong Teng, Yang Yang, Chen Liang, Yanlei Ge, Pengguo Hou, Jialin Liu, Weiwei Gao, Yi Zhang, Yingying Feng, Cheng Tao, Xu Huang, Pinhua Pan, Hong Luo, Chunmei Yun, Qingyuan Zhan
Transcranial Doppler as a screening test to exclude intracranial hypertension in brain-injured patients: the IMPRESSIT-2 prospective multicenter international study
Frank A. Rasulo, Stefano Calza, Chiara Robba, Fabio Silvio Taccone, Daniele G. Biasucci, Rafael Badenes, Simone Piva, Davide Savo, Giuseppe Citerio, Jamil R. Dibu, Francesco Curto, Martina Merciadri, Paolo Gritti, Paola Fassini, Soojin Park, Massimo Lamperti, Pierre Bouzat, Paolo Malacarne, Arturo Chieregato, Rita Bertuetti, Raffaele Aspide, Alfredo Cantoni, Victoria McCredie, Lucrezia Guadrini, Nicola Latronico
Volunteerism during humanitarian crises: a practical guide
Heatherlee Bailey, Lewis J. Kaplan
The effect of treatment and clinical course during Emergency Department stay on severity scoring and predicted mortality risk in Intensive Care patients
Bart G. J. Candel, Wouter Raven, Heleen Lameijer, Wendy A. M. H. Thijssen, Fabian Termorshuizen, Christiaan Boerma, Nicolette F. de Keizer, Evert de Jonge, Bas de Groot
Ultrasound localization of central vein catheter tip by contrast-enhanced transthoracic ultrasonography: a comparison study with trans-esophageal echocardiography
Francesco Corradi, Fabio Guarracino, Gregorio Santori, Claudia Brusasco, Guido Tavazzi, Gabriele Via, Silvia Mongodi, Francesco Mojoli, Raffaello Umberto Dario Biagini, Alessandro Isirdi, Federico Dazzi, Chiara Robba, Luigi Vetrugno, Francesco Forfori, Maria Lidia Bologna, Alessandro Cardu, Laura Crocetti, Francesco Cundari, Elisa Del Frate, Samuele Ferrari, Alberto Laffi, Elena Marrucci, Marco Monfroni, Chiara Piagnani, Erika Taddei, Ludovica Tecchi, Sara Tempini, Debora Tognarelli, Carmelo Vullo
Identifying clinical subtypes in sepsis-survivors with different one-year outcomes: a secondary latent class analysis of the FROG-ICU cohort
Sabri Soussi, Divya Sharma, Peter Jüni, Gerald Lebovic, Laurent Brochard, John C. Marshall, Patrick R. Lawler, Margaret Herridge, Niall Ferguson, Lorenzo Del Sorbo, Elodie Feliot, Alexandre Mebazaa, Erica Acton, Jason N. Kennedy, Wei Xu, Etienne Gayat, Claudia C. Dos Santos, Sabri Soussi, Alexandre Mebazaa, Etienne Gayat, Sabri Soussi, Laurent Brochard, John C. Marshall, Margaret Herridge, Claudia C. Dos Santos
Correction to: Actively implementing an evidence-based feeding guideline for critically ill patients (NEED): a multicenter, cluster-randomized, controlled trial
Lu Ke, Jiajia Lin, Gordon S. Doig, Arthur R. H. van Zanten, Yang Wang, Juan Xing, Zhongheng Zhang, Tao Chen, Lixin Zhou, Dongpo Jiang, Qindong Shi, Jiandong Lin, Jun Liu, Aibin Cheng, Yafeng Liang, Peiyang Gao, Junli Sun, Wenming Liu, Zhenyu Yang, Rumin Zhang, Wei Xing, An Zhang, Zhigang Zhou, Tingfa Zhou, Yang Liu, Fei Tong, Qiuhui Wang, Aijun Pan, Xiaobo Huang, Chuming Fan, Weihua Lu, Dongwu Shi, Lei Wang, Wei Li, Liming Gu, Yingguang Xie, Rongqing Sun, Feng Guo, Lin Han, Lihua Zhou, Xiangde Zheng, Feng Shan, Jianbo Liu, Yuhang Ai, Yan Qu, Liandi Li, Hailing Li, Zhiguo Pan, Donglin Xu, Zhiqiang Zou, Yan Gao, Chunli Yang, Qiuye Kou, Xijing Zhang, Jinglan Wu, Chuanyun Qian, Weixing Zhang, Minjie Zhang, Yuan Zong, Bingyu Qin, Fusen Zhang, Zhe Zhai, Yun Sun, Ping Chang, Bo Yu, Min Yu, Shiying Yuan, Yijun Deng, Liyun Zhao, Bin Zang, Yuanfei Li, Fachun Zhou, Xiaomei Chen, Min Shao, Weidong Wu, Ming Wu, Zhaohui Zhang, Yimin Li, Qiang Guo, Zhiyong Wang, Yuanqi Gong, Yunlin Song, Kejian Qian, Yongjian Feng, Baocai Fu, Xueyan Liu, Zhiping Li, Chuanyong Gong, Cheng Sun, Jian Yu, Zhongzhi Tang, Linxi Huang, Biao Ma, Zhijie He, Qingshan Zhou, Rongguo Yu, Zhihui Tong, Weiqin Li, Lu Ke, Jiajia Lin, Zhihui Tong, Weiqin Li, Yang Wang, Juan Xing, Zhongheng Zhang, Feng Guo, Tao Chen, Lixin Zhou, Dongpo Jiang, Qindong Shi, Jiandong Lin, Jun Liu, Aibin Cheng, Yafeng Liang, Peiyang Gao, Junli Sun, Wenming Liu, Zhenyu Yang, Rumin Zhang, Wei Xing, An Zhang, Zhigang Zhou, Tingfa Zhou, Yang Liu, Fei Tong, Qiuhui Wang, Aijun Pan, Xiaobo Huang, Chuming Fan, Weihua Lu, Dongwu Shi, Lei Wang, Wei Li, Liming Gu, Yingguang Xie, Rongqing Sun, Lin Han, Lihua Zhou, Xiangde Zheng, Feng Shan, Liandi Li, Jianbo Liu, Yuhang Ai, Yan Qu, Hailing Li, Zhiguo Pan, Donglin Xu, Zhiqiang Zou, Yan Gao, Chunli Yang, Qiuye Kou, Xijing Zhang, Jinglan Wu, Chuanyun Qian, Weixing Zhang, Minjie Zhang, Yongjian Feng, Yuan Zong, Bingyu Qin, Fusen Zhang, Zhe Zhai, Yun Sun, Ping Chang, Bo Yu, Min Yu, Shiying Yuan, Yijun Deng, Liyun Zhao, Bin Zang, Yuanfei Li, Fachun Zhou, Xiaomei Chen, Min Shao, Weidong Wu, Ming Wu, Zhaohui Zhang, Yimin Li, Qiang Guo, Zhiyong Wang, Yuanqi Gong, Yunlin Song, Kejian Qian, Baocai Fu, Xueyan Liu, Zhiping Li, Chuanyong Gong, Cheng Sun, Jian Yu, Zhongzhi Tang, Linxi Huang, Biao Ma, Zhijie He, Qingshan Zhou, Rongguo Yu
Permissive azotemia during acute kidney injury enables more rapid renal recovery and less renal fibrosis: a hypothesis and clinical development plan
Lakhmir S. Chawla
Membrane adsorption in vancomycin treatment is membrane type dependent in CVVHDF: dose correction is crucial
Patrick M. Honore, Sebastien Redant, Pharan Djimafo, Thierry Preseau, Bogdan Vasile Cismas, Keitiane Kaefer, Leonel Barreto Gutierrez, Sami Anane, Rachid Attou, Andrea Gallerani, David De Bels
Early prolonged prone position in noninvasively ventilated patients with SARS-CoV-2-related moderate-to-severe hypoxemic respiratory failure: clinical outcomes and mechanisms for treatment response in the PRO-NIV study
Giovanni Musso, Claudio Taliano, Federica Molinaro, Caterina Fonti, Deliana Veliaj, Davide Torti, Elena Paschetta, Elisabetta Castagna, Giorgio Carbone, Luigi Laudari, Claudio Aseglio, Edoardo Zocca, Sonia Chioni, Laura Ceretto Giannone, Federica Arabia, Cecilia Deiana, Francesca Maria Benato, Marta Druetta, Giorgio Campagnola, Margherita Borsari, Martina Mucci, Tiziana Rubatto, Mara Peyronel, Gloria Tirabassi
Assessing the SAfety and FEasibility of bedside portable low-field brain Magnetic Resonance Imaging in patients on ECMO (SAFE-MRI ECMO study): study protocol and first case series experience
Sung-Min Cho, Christopher Wilcox, Steven Keller, Matthew Acton, Hannah Rando, Eric Etchill, Katherine Giuliano, Errol L. Bush, Haris I. Sair, John Pitts, Bo Soo Kim, Glenn Whitman
Cardiopulmonary resuscitation duration and favorable neurological outcome after out-of-hospital cardiac arrest: a nationwide multicenter observational study in Japan (the JAAM-OHCA registry)
Tasuku Matsuyama, Bon Ohta, Kosuke Kiyohara, Tetsuhisa Kitamura
Comparison of the predictive ability of clinical frailty scale and hospital frailty risk score to determine long-term survival in critically ill patients: a multicentre retrospective cohort study
Ashwin Subramaniam, Ryo Ueno, Ravindranath Tiruvoipati, Velandai Srikanth, Michael Bailey, David Pilcher
Sequential use of midazolam and dexmedetomidine for long-term sedation may reduce weaning time in selected critically ill, mechanically ventilated patients: a randomized controlled study
Yongfang Zhou, Jie Yang, Bo Wang, Peng Wang, Zhen Wang, Yunqin Yang, Guopeng Liang, Xiaorong jing, Xiaodong Jin, Zhongwei Zhang, Yiyun Deng, Chenggong Hu, Xuelian Liao, Wanhong Yin, Zhihong Tang, Yongming Tian, Liyuan Tao, Yan Kang
Routine use of indirect calorimetry in critically ill patients: pros and cons
Elisabeth De Waele, Arthur R. H. van Zanten
Early intubation and decreased in-hospital mortality in patients with coronavirus disease 2019
Ryo Yamamoto, Daiki Kaito, Koichiro Homma, Akira Endo, Takashi Tagami, Morio Suzuki, Naoyuki Umetani, Masayuki Yagi, Eisaku Nashiki, Tomohiro Suhara, Hiromasa Nagata, Hiroki Kabata, Koichi Fukunaga, Kazuma Yamakawa, Mineji Hayakawa, Takayuki Ogura, Atsushi Hirayama, Hideo Yasunaga, Junichi Sasaki
When to start vasopressin in septic shock: the strategy we propose
Philippe Guerci, Thibaut Belveyre, Nicolas Mongardon, Emmanuel Novy
Effects on health-related quality of life of interventions affecting survival in critically ill patients: a systematic review
Ottavia Pallanch, Alessandro Ortalda, Paolo Pelosi, Nicola Latronico, Chiara Sartini, Gaetano Lombardi, Cristiano Marchetti, Nicolò Maimeri, Alberto Zangrillo, Luca Cabrini
Lung response to prone positioning in mechanically-ventilated patients with COVID-19
Alessandro Protti, Alessandro Santini, Francesca Pennati, Chiara Chiurazzi, Michele Ferrari, Giacomo E. Iapichino, Luca Carenzo, Francesca Dalla Corte, Ezio Lanza, Nicolò Martinetti, Andrea Aliverti, Maurizio Cecconi
Machine learning derivation of four computable 24-h pediatric sepsis phenotypes to facilitate enrollment in early personalized anti-inflammatory clinical trials
Yidi Qin, Kate F. Kernan, Zhenjiang Fan, Hyun-Jung Park, Soyeon Kim, Scott W. Canna, John A. Kellum, Robert A. Berg, David Wessel, Murray M. Pollack, Kathleen Meert, Mark Hall, Christopher Newth, John C. Lin, Allan Doctor, Tom Shanley, Tim Cornell, Rick E. Harrison, Athena F. Zuppa, Russell Banks, Ron W. Reeder, Richard Holubkov, Daniel A. Notterman, J. Michael Dean, Joseph A. Carcillo
Extracorporeal cardiopulmonary resuscitation in adult patients with out-of-hospital cardiac arrest: a retrospective large cohort multicenter study in Japan
Akihiko Inoue, Toru Hifumi, Tetsuya Sakamoto, Hiroshi Okamoto, Jun Kunikata, Hideto Yokoi, Hirotaka Sawano, Yuko Egawa, Shunichi Kato, Kazuhiro Sugiyama, Naofumi Bunya, Takehiko Kasai, Shinichi Ijuin, Shinichi Nakayama, Jun Kanda, Seiya Kanou, Toru Takiguchi, Shoji Yokobori, Hiroaki Takada, Kazushige Inoue, Ichiro Takeuchi, Hiroshi Honzawa, Makoto Kobayashi, Tomohiro Hamagami, Wataru Takayama, Yasuhiro Otomo, Kunihiko Maekawa, Takafumi Shimizu, Satoshi Nara, Michitaka Nasu, Kuniko Takahashi, Yoshihiro Hagiwara, Shigeki Kushimoto, Reo Fukuda, Takayuki Ogura, Shin-ichiro Shiraishi, Ryosuke Zushi, Norio Otani, Migaku Kikuchi, Kazuhiro Watanabe, Takuo Nakagami, Tomohisa Shoko, Nobuya Kitamura, Takayuki Otani, Yoshinori Matsuoka, Makoto Aoki, Masaaki Sakuraya, Hideki Arimoto, Koichiro Homma, Hiromichi Naito, Shunichiro Nakao, Tomoya Okazaki, Yoshio Tahara, Yasuhiro Kuroda, Asae Senda, Hajime Suzuki, Atsunori Tanimoto, Kanta Kitagawa, Yoichi Katayama, Nobuaki Igarashi, Masayuki Kawano, Yuji Kuroki, Tadashi Umehara, Yukari Sasaki, Naoki Tominaga, Takuro Hamaguchi, Takuma Sakai, Takeru Abe, Hiroaki Hanafusa, Yuki Yamaoka, Yumi Kakizaki, Shinya Sakato, Shiho Kashiwabara, Takashi Kadoya, Kayo Misumi, Takaomi Kobayashi, Sou Yamada, Masakazu Kobayashi, Naoko Akashi, Masamune Kuno, Jun Maruyama, Hitoshi Kobata, Mitsuhito Soh, Kasumi Shirasaki, Daiki Shiba, Shutaro Isokawa, Masatoshi Uchida, Atsushi Sakurai, Hirotaka Tatsukawa, Marie Nishikawa, Mitsuaki Kojima, Ryohei Kosaki, Takashi Shimazui, Hiroki Kinoshita, Yusuke Sawada, Ryo Yamamoto, Yuya Masuzawa, Kazuki Matsumura, Junya Shimazaki
Diagnostic concordance between BioFire® FilmArray® Pneumonia Panel and culture in patients with COVID-19 pneumonia admitted to intensive care units: the experience of the third wave in eight hospitals in Colombia
Francisco José Molina, Luz Elena Botero, Juan Pablo Isaza, Luz Elena Cano, Lucelly López, Leidy Tamayo, Antoni Torres
Higher serum haptoglobin levels were associated with improved outcomes of patients with septic shock
Peng Lan, Peihao Yu, Jun Ni, Jiancang Zhou
Correction: The effect of treatment and clinical course during Emergency Department stay on severity scoring and predicted mortality risk in Intensive Care patients
Bart G. J. Candel, Wouter Raven, Heleen Lameijer, Wendy A. M. H. Thijssen, Fabian Termorshuizen, Christiaan Boerma, Nicolette F. de Keizer, Evert de Jonge, Bas de Groot
Impact of critical illness and withholding of early parenteral nutrition in the pediatric intensive care unit on long-term physical performance of children: a 4-year follow-up of the PEPaNIC randomized controlled trial
Ilse Vanhorebeek, An Jacobs, Liese Mebis, Karolijn Dulfer, Renate Eveleens, Hanna Van Cleemput, Pieter J. Wouters, Ines Verlinden, Koen Joosten, Sascha Verbruggen, Greet Van den Berghe
Clinical and biochemical endpoints and predictors of response to plasma exchange in septic shock: results from a randomized controlled trial
Klaus Stahl, Philipp Wand, Benjamin Seeliger, Pedro David Wendel-Garcia, Julius J. Schmidt, Bernhard M. W. Schmidt, Andrea Sauer, Felix Lehmann, Ulrich Budde, Markus Busch, Olaf Wiesner, Tobias Welte, Hermann Haller, Heiner Wedemeyer, Christian Putensen, Marius M. Hoeper, Christian Bode, Sascha David
Hemoperfusion: technical aspects and state of the art
Claudio Ronco, Rinaldo Bellomo
Hospital-onset sepsis and community-onset sepsis in critical care units in Japan: a retrospective cohort study based on a Japanese administrative claims database
Mayuko Tonai, Atsushi Shiraishi, Toshiyuki Karumai, Akira Endo, Hirotada Kobayashi, Kiyohide Fushimi, Yoshiro Hayashi
Termination-of-resuscitation rule in the emergency department for patients with refractory out-of-hospital cardiac arrest: a nationwide, population-based observational study
Yoshikazu Goto, Akira Funada, Tetsuo Maeda, Yumiko Goto
Impact of prolonged requirement for insulin on 90-day mortality in critically ill patients without previous diabetic treatments: a post hoc analysis of the CONTROLING randomized control trial
François Thouy, Julien Bohé, Bertrand Souweine, Hassane Abidi, Jean-Pierre Quenot, Fabrice Thiollière, Jean Dellamonica, Jean-Charles Preiser, Jean-François Timsit, Vincent Brunot, Amna Klich, Nicholas Sedillot, Xavier Tchenio, Jean-Baptiste Roudaut, Nicolas Mottard, Hervé Hyvernat, Florent Wallet, Pierre-Eric Danin, Julio Badie, Richard Jospe, Jérôme Morel, Ali Mofredj, Abdelhamid Fatah, Jocelyne Drai, Anne Mialon, Ali Ait Hssain, Alexandre Lautrette, Eric Fontaine, Charles-Hervé Vacheron, Delphine Maucort-Boulch, Kada Klouche, Claire Dupuis
Correction to: Pain and sedation management and monitoring in pediatric intensive care units across Europe: an ESPNIC survey
Marco Daverio, Florian von Borell, Anne-Sylvie Ramelet, Francesca Sperotto, Paula Pokorna, Sebastian Brenner, Maria Cristina Mondardini, Dick Tibboel, Angela Amigoni, Erwin Ista, Ermira Kola, Maria Vittinghoff, Elim Duval, Branka Polić, Frédéric Valla, Felix Neunhoeffer, Tziouvas Konstantinos, Zoltán Györgyi, Mong Hoi Tan, Antigona Hasani, Edita Poluzioroviene, Reinis Balmaks, Mickael Afanetti, Gunnar Bentsen, Alicja Bartkowska-Sniatkowska, Cristina Camilo, Dusica Simic, Yolanda M. López-Fernández, Janet Mattsson, Hasan Özen, Dmytro Dmytriiev, Joseph C. Manning, Hakan Tekgüç
Prevalence and prognostic value of preexisting sarcopenia in patients with mechanical ventilation: a systematic review and meta-analysis
Tingting Jiang, Taiping Lin, Xiaoyu Shu, Quhong Song, Miao Dai, Yanli Zhao, Li Huang, Xiangping Tu, Jirong Yue
Early short course of neuromuscular blocking agents in patients with COVID-19 ARDS: a propensity score analysis
Gianluigi Li Bassi, Kristen Gibbons, Jacky Y. Suen, Heidi J. Dalton, Nicole White, Amanda Corley, Sally Shrapnel, Samuel Hinton, Simon Forsyth, John G. Laffey, Eddy Fan, Jonathon P. Fanning, Mauro Panigada, Robert Bartlett, Daniel Brodie, Aidan Burrell, Davide Chiumello, Alyaa Elhazmi, Mariano Esperatti, Giacomo Grasselli, Carol Hodgson, Shingo Ichiba, Carlos Luna, Eva Marwali, Laura Merson, Srinivas Murthy, Alistair Nichol, Mark Ogino, Paolo Pelosi, Antoni Torres, Pauline Yeung Ng, John F. Fraser, Tala Al-Dabbous, Huda Alfoudri, Mohammed Shamsah, Subbarao Elapavaluru, Ashley Berg, Christina Horn, Yunis Mayasi, Stephan Schroll, Dan Meyer, Jorge Velazco, Ludmyla Ploskanych, Wanda Fikes, Rohini Bagewadi, Marvin Dao, Haley White, Dan Meyer, Ashley Ehlers, Maysoon Shalabi-McGuire, Trent Witt, Lorenzo Grazioli, Luca Lorini, E. Wilson Grandin, Jose Nunez, Tiago Reyes, Diarmuid OBriain, Stephanie Hunter, Mahesh Ramanan, Julia Affleck, Hemanth Hurkadli Veerendra, Sumeet Rai, Josie Russell-Brown, Mary Nourse, Mark Joseph, Brook Mitchell, Martha Tenzer, Ryuzo Abe, Hwa Jin Cho, In Seok Jeong, Nadeem Rahman, Vivek Kakar, Nicolas Brozzi, Omar Mehkri, Sudhir Krishnan, Abhijit Duggal, Stuart Houltham, Jerónimo Graf, Roderigo Diaz, Roderigo Orrego, Camila Delgado, Joyce González, Maria Soledad Sanchez, Michael Piagnerelli, Josefa Valenzuela Sarrazin, A./Prof. Gustavo Zabert, Lucio Espinosa, Paulo Delgado, Victoria Delgado, Diego Fernando Bautista Rincón, Angela Maria Marulanda Yanten, Melissa Bustamante Duque, Daniel Brodie, Alyaa Elhazmi, Abdullah Al-Hudaib, Maria Callahan, M. Azhari Taufik, Elizabeth Yasmin Wardoyo, Margaretha Gunawan, Nurindah S. Trisnaningrum, Vera Irawany, Muhammad Rayhan, Mauro Panigada, Antonia Pesenti, Alberto Zanella, Michela Leone, Giacomo Grasselli, Silvia Coppola, Sebastiano Colombo, Massimo Antonelli, Simone Carelli, Domenico L. Grieco, Motohiro Asaki, Kota Hoshino, Leonardo Salazar, Laura Duarte, John Laffey, Bairbre McNicholas, David Cosgrave, Joseph McCaffrey, Allison Bone, Yusuff Hakeem, James Winearls, Mandy Tallott, David Thomson, Christel Arnold-Day, Jerome Cupido, Zainap Fanie, Malcom Miller, Lisa Seymore, Dawid van Straaten, Ali Ait Hssain, Jeffrey Aliudin, Al-Reem Alqahtani, Khoulod Mohamed, Ahmed Mohamed, Darwin Tan, Joy Villanueva, Ahmed Zaqout, Ethan Kurtzman, Arben Ademi, Ana Dobrita, Khadija El Aoudi, Juliet Segura, Gezy Giwangkancana, Shinichiro Ohshimo, Koji Hoshino, Saito Hitoshi, Javier Osatnik, Anne Joosten, Antoni Torres, Minlan Yang, Ana Motos, Carlos Luna, Francisco Arancibia, Virginie Williams, Alexandre Noel, Nestor Luque, Trieu Huynh Trung, Sophie Yacoub, Marina Fantini, Ruth Noemi Jorge García, Enrique Chicote Alvarez, Anna Greti, Adrian Ceccato, Angel Sanchez, Ana Loza Vazquez, Ferran Roche-Campo, Diego Franch-Llasat, Divina Tuazon, Marcelo Amato, Luciana Cassimiro, Flavio Pola, Francis Ribeiro, Guilherme Fonseca, Heidi Dalton, Mehul Desai, Erik Osborn, Hala Deeb, Antonio Arcadipane, Gennaro Martucci, Giovanna Panarello, Chiara Vitiello, Claudia Bianco, Giovanna Occhipinti, Matteo Rossetti, Raffaele Cuffaro, Sung-Min Cho, Hiroaki Shimizu, Naoki Moriyama, Jae-Burm Kim, Nobuya Kitamura, Johannes Gebauer, Toshiki Yokoyama, Abdulrahman Al-Fares, Sarah Buabbas, Esam Alamad, Fatma Alawadhi, Kalthoum Alawadi, Hiro Tanaka, Satoru Hashimoto, Masaki Yamazaki, Tak-Hyuck Oh, Mark Epler, Cathleen Forney, Louise Kruse, Jared Feister, Joelle Williamson, Katherine Grobengieser, Eric Gnall, Sasha Golden, Mara Caroline, Timothy Shapiro, Colleen Karaj, Lisa Thome, Lynn Sher, Mark Vanderland, Mary Welch, Sherry McDermott, Matthew Brain, Sarah Mineall, Dai Kimura, Luca Brazzi, Gabriele Sales, Tawnya Ogston, Dave Nagpal, Karlee Fischer, Roberto Lorusso, Rajavardhan Rangappa, Sujin Rai, Argin Appu, Mariano Esperatti, Diarmuid OBriain, Edmund G. Carton, Ayan Sen, Amanda Palacios, Deborah Rainey, Gordan Samoukoviv, Josie Campisi, Lucia Durham, Emily Neumann, Cassandra Seefeldt, Octavio Falcucci, Amanda Emmrich, Jennifer Guy, Carling Johns, Kelly Potzner, Catherine Zimmermann, Angelia Espinal, Nina Buchtele, Michael Schwameis, Stephanie-Susanne Stecher, Delila Singh, Michaela Barnikel, Lukas Arenz, Akram Zaaqoq, Lan Anh Galloway, Caitlin Merley, Alistair Nichol, Marc Csete, Luisa Quesada, Isabela Saba, Daisuke Kasugai, Hiroaki Hiraiwa, Taku Tanaka, Eva Marwali, Yoel Purnama, Santi Rahayu Dewayanti, Ardiyan, Dafsah Arifa Juzar, Debby Siagian, Yih-Sharng Chen, Mark Ogino, Indrek Ratsep, Getter Oigus, Kristo Erikson, Andra-Maris Post, Lauri Enneveer, Piret Sillaots, Frank Manetta, Effe Mihelis, Iam Claire Sarmiento, Mangala Narasimhan, Michael Varrone, Mamoru Komats, Julia Garcia-Diaz, Catherine Harmon, S. Veena Satyapriya, Amar Bhatt, Nahush A. Mokadam, Alberto Uribe, Alicia Gonzalez, Haixia Shi, Johnny McKeown, Joshua Pasek, Juan Fiorda, Marco Echeverria, Rita Moreno, Bishoy Zakhary, Marco Cavana, Alberto Cucino, Giuseppe Foti, Marco Giani, Vincenzo Russotto, Davide Chiumello, Valentina Castagna, Andrea DellAmore, Paolo Navalesi, Hoi-Ping Shum, Alain Vuysteke, Asad Usman, Andrew Acker, Benjamin Smood, Blake Mergler, Federico Sertic, Madhu Subramanian, Alexandra Sperry, Nicolas Rizer, Erlina Burhan, Menaldi Rasmin, Ernita Akmal, Faya Sitompul, Navy Lolong, Bhat Naivedh, Simon Erickson, Peter Barrett, David Dean, Julia Daugherty, Antonio Loforte, Irfan Khan, Mohammed Abraar Quraishi, Olivia DeSantis, Dominic So, Darshana Kandamby, Jose M. Mandei, Hans Natanael, Eka YudhaLantang, Anastasia Lantang, Surya Oto Wijaya, Anna Jung, George Ng, Wing Yiu Ng, Pauline Yeung Ng, Shu Fang, Alexis Tabah, Megan Ratcliffe, Maree Duroux, Shingo Adachi, Shota Nakao, Pablo Blanco, Ana Prieto, Jesús Sánchez, Meghan Nicholson, Warwick Butt, Alyssa Serratore, Carmel Delzoppo, Pierre Janin, Elizabeth Yarad, Richard Totaro, Jennifer Coles, Bambang Pujo, Robert Balk, Andy Vissing, Esha Kapania, James Hays, Samuel Fox, Garrett Yantosh, Pavel Mishin, Saptadi Yuliarto, Kohar Hari Santoso, Susanthy Djajalaksana, Arie Zainul Fatoni, Masahiro Fukuda, Keibun Liu, Paolo Pelosi, Denise Battaglini, Juan Fernando Masa Jiménez, Diego Bastos, Sérgio Gaião, Desy Rusmawatiningtyas, Jessica Buchner, Young-Jae Cho, Su Hwan Lee, Tatsuya Kawasaki, Laveena Munshi, Pranya Sakiyalak, Prompak Nitayavardhana, Tamara Seitz, Rakesh Arora, David Kent, Daniel Marino, Swapnil Parwar, Andrew Cheng, Jennene Miller, Shigeki Fujitani, Naoki Shimizu, Jai Madhok, Clark Owyang, Hergen Buscher, Claire Reynolds, Olavi Maasikas, Aleksan Beljantsev, Vladislav Mihnovits, Takako Akimoto, Mariko Aizawa, Kanako Horibe, Ryota Onodera, Carol Hodgson, Aidan Burrell, Meredith Young, Timothy George, Kiran Shekar, Niki McGuinness, Lacey Irvine, Brigid Flynn, Tomoyuki Endo, Kazuhiro Sugiyama, Keiki Shimizu, Eddy Fan, Kathleen Exconde, Shingo Ichiba, Leslie Lussier, Gösta Lotz, Maximilian Malfertheiner, Lars Maier, Esther Dreier, Neurinda Permata Kusumastuti, Colin McCloskey, Al-Awwab Dabaliz, Tarek B. Elshazly, Josiah Smith, Konstanty S. Szuldrzynski, Piotr Bielański, Yusuff Hakeem, Keith Wille, Srinivas Murthy, Ken Kuljit S. Parhar, Kirsten M. Fiest, Cassidy Codan, Anmol Shahid, Mohamed Fayed, Timothy Evans, Rebekah Garcia, Ashley Gutierrez, Hiroaki Shimizu, Tae Song, Rebecca Rose, Suzanne Bennett, Denise Richardson, Giles Peek, Lovkesh Arora, Kristina Rappapport, Kristina Rudolph, Zita Sibenaller, Lori Stout, Alicia Walter, Daniel Herr, Nazli Vedadi, Robert Bartlett, Antonio Pesenti, Shaun Thompson, Lace Sindt, Sean Rajnic, Cale Ewald, Julie Hoffman, Xiaonan Ying, Ryan Kennedy, Matthew Griffee, Anna Ciullo, Yuri Kida, Ricard Ferrer Roca, JordI Riera, Sofia Contreras, Cynthia Alegre, Christy Kay, Irene Fischer, Elizabeth Renner, Hayato Taniguci, John Fraser, Gianluigi Li Bassi, Jacky Suen, Adrian Barnett, Nicole White, Kristen Gibbons, Simon Forsyth, Amanda Corley, India Pearse, Samuel Hinton, Gabriella Abbate, Halah Hassan, Silver Heinsar, Varun A. Karnik, Katrina Ki, Hollier F. ONeill, Nchafatso Obonyo, Leticia Pretti Pimenta, Janice D. Reid, Kei Sato, Kiran Shekar, Aapeli Vuorinen, Karin S. Wildi, Emily S. Wood, Stephanie Yerkovich, James Lee, Daniel Plotkin, Barbara Wanjiru Citarella, Laura Merson, Emma Hartley, Bastian Lubis, Takanari Ikeyama, Balu Bhaskar, Jae-Seung Jung, Shay McGuinness, Glenn Eastwood, Sandra Rossi Marta, Fabio Guarracino, Stacy Gerle, Emily Coxon, Bruno Claro, Daniel Loverde, Namrata Patil, Vieri Parrini, Angela McBride, Kathryn Negaard, Angela Ratsch, Ahmad Abdelaziz, Juan David Uribe, Adriano Peris, Mark Sanders, Dominic Emerson, Muhammad Kamal, Pedro Povoa, Roland Francis, Ali Cherif, Sunimol Joseph, Matteo Di Nardo, Micheal Heard, Kimberly Kyle, Ray A. Blackwell, Michael Piagnerelli, Patrick Biston, Hye Won Jeong, Reanna Smith, Yogi Prawira, Giorgia Montrucchio, Arturo Huerta Garcia, Nahikari Salterain, Bart Meyns, Marsha Moreno, Rajat Walia, Amit Mehta, Annette Schweda, Moh Supriatna, Cenk Kirakli, Melissa Williams, Kyung Hoon Kim, Alexandra Assad, Estefania Giraldo, Wojtek Karolak, Martin Balik, Elizabeth Pocock, Evan Gajkowski, Kanamoto Masafumi, Nicholas Barrett, Yoshihiro Takeyama, Sunghoon Park, Faizan Amin, Fina Meilyana Andriyani, Serhii Sudakevych, Angela Ratsch, Magdalena Vera, Rodrigo Cornejo, Patrícia Schwarz, Ana Carolina Mardini, Thais de Paula, Ary Serpa Neto, Andrea Villoldo, Alexandre Siciliano Colafranceschi, Alejandro Ubeda Iglesias, Juan Granjean, Lívia Maria Garcia Melro, Giovana Fioravante Romualdo, Diego Gaia, Helmgton Souza, Filomena Galas, Rafael Máñez Mendiluce, Alejandra Sosa, Ignacio Martinez, Hiroshi Kurosawa, Juan Salgado, Beate Eric Hugi-MayrCharbonneau, Vitor Salvatore Barzilai, Veronica Monteiro, Rodrigo Ribeiro de Souza, Michael Harper, Hiroyuki Suzuki, Celina Adams, Jorge Brieva, George Nyale, Faisal Saleem Eltatar, Jihan Fatani, Husam Baeissa, Ayman AL Masri, Ahmed Rabie, Mok Yee Hui, Masahiro Yamane, Hanna Jung, Ayorinde Mojisola Margaret, Newell Nacpil, Katja Ruck, Rhonda Bakken, Claire Jara, Tim Felton, Lorenzo Berra, Bobby Shah, Arpan Chakraborty, Monika Cardona, Gerry Capatos, Bindu Akkanti, Abiodun Orija, Harsh Jain, Asami Ito, Brahim Housni, Sennen Low, Koji Iihara, Joselito Chavez, Kollengode Ramanathan, Gustavo Zabert, Krubin Naidoo, Ian Seppelt, Marlice VanDyk, Sarah MacDonald, Shingo Ichiba, Randy McGregor, Teka Siebenaler, Hannah Flynn, Kristi Lofton, Toshiyuki Aokage, Kazuaki Shigemitsu, Andrea Moscatelli, Giuseppe Fiorentino, Matthias Baumgaertel, Serge Eddy Mba, Jana Assy, Amelya Hutahaean, Holly Roush, Kay A. Sichting, Francesco Alessandri, Debra Burns, Ahmed Rabie, Gavin Salt, Carl P. Garabedian, Jonathan Millar, Malcolm Sim, Adrian Mattke, Danny McAuley, Jawad Tadili, Tim Frenzel, Yaron Bar-Lavie, Aaron Blandino Ortiz, Jackie Stone, Alexis Tabah, Antony Attokaran, Michael Farquharson, Brij Patel, Derek Gunning, Kenneth Baillie, Pia Watson, Kenji Tamai, Gede Ketut Sajinadiyasa, Dyah Kanyawati, Marcello Salgado, Assad Sassine, Bhirowo Yudo, Scott McCaul, Bongjin Lee, Sang Min Lee, Arnon Afek, Yoshiaki Iwashita, Bambang Pujo Semedi, Neurinda Permata Kusumastuti, Jack Metiva, Nicole Van Belle, Ignacio Martin-Loeches, Lenny Ivatt, Chia Yew Woon, Hyun Mi Kang, Timothy Smith, Erskine James, Nawar Al-Rawas, Yudai Iwasaki, Kenny Chan King-Chung, Vadim Gudzenko, Beate Hugi-Mayr, Fabio Taccone, Fajar Perdhana, Yoan Lamarche, Joao Miguel Ribeiro, Nikola Bradic, Klaartje Van den Bossche, Oude Lansink, Gurmeet Singh, Gerdy Debeuckelaere, Henry T. Stelfox, Cassia Yi, Jennifer Elia, Thomas Tribble, Shyam Shankar, Raj Padmanabhan, Bill Hallinan, Luca Paoletti, Yolanda Leyva, Tatuma Fykuda, Jenelle Badulak, Jillian Koch, Amy Hackman, Lisa Janowaik, Deb Hernandez, Jennifer Osofsky, Katia Donadello, Aizah Lawang, Josh Fine, Benjamin Davidson, Andres Oswaldo Razo Vazquez
TTCOV19: timing of tracheotomy in SARS-CoV-2-infected patients: a multicentre, single-blinded, randomized, controlled trial
Måns Eeg-Olofsson, Nina Pauli, Louise Hafsten, Josephine Jacobsson, Christopher Lundborg, Magnus Brink, Helen Larsson, Ellen Lindell, Karin Löwhagen, Magnus Gisslén, Henrik Bergquist
Medical nutrition therapy and clinical outcomes in critically ill adults: a European multinational, prospective observational cohort study (EuroPN)
Martin Matejovic, Olivier Huet, Karolien Dams, Gunnar Elke, Clara Vaquerizo Alonso, Akos Csomos, Łukasz J. Krzych, Romano Tetamo, Zudin Puthucheary, Olav Rooyackers, Inga Tjäder, Helmut Kuechenhoff, Wolfgang H. Hartl, Michael Hiesmayr
Pulmonary consolidation alters the ultrasound estimate of pleural fluid volume when considering chest drainage in patients on ECMO
Martin Balik, Masego Candy Mokotedi, Michal Maly, Michal Otahal, Zdenek Stach, Eva Svobodova, Marek Flaksa, Jan Rulisek, Tomas Brozek, Michal Porizka
Web-based application for predicting the potential target phenotype for recombinant human thrombomodulin therapy in patients with sepsis: analysis of three multicentre registries
Tadahiro Goto, Daisuke Kudo, Ryo Uchimido, Mineji Hayakawa, Kazuma Yamakawa, Toshikazu Abe, Atsushi Shiraishi, Shigeki Kushimoto
Hidden Harlequin syndrome in neonatal and pediatric VA-ECMO
Yael Levy, Julie Starck, Anne-Lise Mary, Yohan Soreze, Sandrine Jean, Bernard Kreitmann, Pierre-Louis Léger, Jerome Rambaud
Evolving outcomes of extracorporeal membrane oxygenation during the first 2 years of the COVID-19 pandemic: a systematic review and meta-analysis
Ryan Ruiyang Ling, Kollengode Ramanathan, Jackie Jia Lin Sim, Suei Nee Wong, Ying Chen, Faizan Amin, Shannon M. Fernando, Bram Rochwerg, Eddy Fan, Ryan P. Barbaro, Graeme MacLaren, Kiran Shekar, Daniel Brodie
Long-term ketamine infusion-induced cholestatic liver injury in COVID-19-associated acute respiratory distress syndrome
Pedro David Wendel-Garcia, Rolf Erlebach, Daniel Andrea Hofmaenner, Giovanni Camen, Reto Andreas Schuepbach, Christoph Jüngst, Beat Müllhaupt, Jan Bartussek, Philipp Karl Buehler, Rea Andermatt, Sascha David
Difference of 11 years between two periods of VV-ECMO does not impact mortality in large centres: we are not sure
Patrick M. Honore, Sebastien Redant, Pharan Djimafo, Thierry Preseau, Bogdan Vasile Cismas, Keitiane Kaefer, Leonel Barreto Gutierrez, Sami Anane, Andrea Gallerani, Rachid Attou
Venous return and mean systemic filling pressure: physiology and clinical applications
Romain Persichini, Christopher Lai, Jean-Louis Teboul, Imane Adda, Laurent Guérin, Xavier Monnet
Effect of erythromycin on mortality and the host response in critically ill patients with sepsis: a target trial emulation
Tom D. Y. Reijnders, Hessel Peters-Sengers, Lonneke A. van Vught, Fabrice Uhel, Marc J. M. Bonten, Olaf L. Cremer, Marcus J. Schultz, Martijn M. Stuiver, Tom van der Poll, Friso M. de Beer, Lieuwe D. J. Bos, Gerie J. Glas, Roosmarijn T. M. van Hooijdonk, Janneke Horn, Laura R. A. Schouten, Marleen Straat, Luuk Wieske, Esther Witteveen, Tom D. Y. Reijnders, Alex R. Schuurman, Tjitske S. R. van Engelen, Liza Pereverzeva, Arie J. Hoogendijk, Mischa A. Huson, Maryse A. Wiewel, Peter M. C. Klein Klouwenberg, David S. Y. Ong, Jos F. Frencken, Maria E. Koster-Brouwer, Kirsten van de Groep, Diana M. Verboom
A multicentre evaluation exploring the impact of an integrated health and social care intervention for the caregivers of ICU survivors
Joanne McPeake, Philip Henderson, Pamela MacTavish, Helen Devine, Malcolm Daniel, Phil Lucie, Lynn Bollan, Lucy Hogg, Mike MacMahon, Sharon Mulhern, Pauline Murray, Laura O’Neill, Laura Strachan, Theodore J. Iwashyna, Martin Shaw, Tara Quasim
Effect of abdominal weight training with and without cough machine assistance on lung function in the patients with prolonged mechanical ventilation: a randomized trial
Tsai-Yi Hung, Wen-Lan Wu, Ho-Chang Kuo, Shih-Feng Liu, Chia-Ling Chang, Hui-Chuan Chang, Yuh-Chyn Tsai, Jui-Fang Liu
Prone positioning improves ventilation–perfusion matching assessed by electrical impedance tomography in patients with ARDS: a prospective physiological study
Yu-xian Wang, Ming Zhong, Min-hui Dong, Jie-qiong Song, Yi-jun Zheng, Wei Wu, Jia-le Tao, Ling Zhu, Xin Zheng
Impairment of neutrophil functions and homeostasis in COVID-19 patients: association with disease severity
Chloé Loyer, Arnaud Lapostolle, Tomas Urbina, Alexandre Elabbadi, Jean-Rémi Lavillegrand, Thomas Chaigneau, Coraly Simoes, Julien Dessajan, Cyrielle Desnos, Mélanie Morin-Brureau, Yannick Chantran, Pierre Aucouturier, Bertrand Guidet, Guillaume Voiriot, Hafid Ait-Oufella, Carole Elbim
High‑flow nasal cannula is not more effective than conventional oxygen therapy for acute exacerbation of COPD with mild hypercapnia: we are not sure
Sergey N. Avdeev, Andrey I. Yaroshetskiy, Galia S. Nuralieva, Ivan S. Avdeev, Anna E. Shmidt
Association between early cumulative fluid balance and successful liberation from invasive ventilation in COVID-19 ARDS patients — insights from the PRoVENT-COVID study: a national, multicenter, observational cohort analysis
Sanchit Ahuja, Harm-Jan de Grooth, Frederique Paulus, Fleur L. van der Ven, Ary Serpa Neto, Marcus J. Schultz, Pieter R. Tuinman, S. Ahuja, J. P. van Akkeren, A. G. Algera, C. K. Algoe, R. B. van Amstel, A. Artigas, O. L. Baur, P. van de Berg, A. E. van den Berg, D. C. J. J. Bergmans, D. I. van den Bersselaar, F. A. Bertens, A. J. G. H. Bindels, M. M. de Boer, S. den Boer, L. S. Boers, M. Bogerd, L. D. J. Bos, M. Botta, J. S. Breel, H. de Bruin, S. de Bruin, C. L. Bruna, L. A. Buiteman-Kruizinga, O. L. Cremer, R. M. Determann, W. Dieperink, D. A. Dongelmans, H. S. Franke, M. S. Galek-Aldridge, M. J. de Graaff, L. A. Hagens, J. J. Haringman, S. T. van der Heide, P. L. J. van der Heiden, N. F. L. Heijnen, S. J. P. Hiel, L. L. Hoeijmakers, L. Hol, M. W. Hollmann, M. E. Hoogendoorn, J. Horn, R. van der Horst, E. L. K. Ie, D. Ivanov, N. P. Juffermans, E. Kho, E. S. de Klerk, A. W. M. M. Koopman-van Gemert, M. Koopmans, S. Kucukcelebi, M. A. Kuiper, D. W. de Lange, N. van Mourik, S. G. Nijbroek, M. Onrust, E. A. N. Oostdijk, F. Paulus, C. J. Pennartz, J. Pillay, L. Pisani, I. M. Purmer, T. C. D. Rettig, J. P. Roozeman, M. T. U. Schuijt, M. J. Schultz, A. Serpa Neto, M. E. Sleeswijk, M. R. Smit, P. E. Spronk, W. Stilma, A. C. Strang, A. M. Tsonas, P. R. Tuinman, C. M. A. Valk, F. L. Veen-Schra, L. I. Veldhuis, P. van Velzen, W. H. van der Ven, A. P. J. Vlaar, P. van Vliet, P. H. J. van der Voort, L. van Welie, H. J. F. T. Wesselink, H. H. van der Wier-Lubbers, B. van Wijk, T. Winters, W. Y. Wong, A. R. H. van Zanten
Comparative incidence of early and late bloodstream and respiratory tract co-infection in patients admitted to ICU with COVID-19 pneumonia versus Influenza A or B pneumonia versus no viral pneumonia: wales multicentre ICU cohort study
Manish Pandey, Alexander May, Laura Tan, Harriet Hughes, Jack Parry Jones, Wendy Harrison, Scott Bradburn, Sam Tyrrel, Babu Muthuswamy, Nidhika Berry, Richard Pugh, Daryn Sutton, Andy Campbell, Matthew Morgan
One-year patient outcomes based on lung morphology in acute respiratory distress syndrome: secondary analysis of LIVE trial
Florian Blanchard, Thomas Godet, Stephanie Pons, Natacha Kapandji, Matthieu Jabaudon, Vincent Degos, Lucile Borao, Adrien Bougle, Antoine Monsel, Emmanuel Futier, Jean-Michel Constantin, Arthur James
Intermediate-risk pulmonary embolism: echocardiography predictors of clinical deterioration
Anthony J. Weekes, Denise N. Fraga, Vitaliy Belyshev, William Bost, Christopher A. Gardner, Nathaniel S. O’Connell
Association of annual hospital septic shock case volume and hospital mortality
Yan Chen, Xu-dong Ma, Xiao-hui Kang, Si-fa Gao, Jin-min Peng, Shan Li, Da-wei Liu, Xiang Zhou, Li Weng, Bin Du
Respiratory distress observation scales to predict weaning outcome
Maxens Decavèle, Emmanuel Rozenberg, Marie-Cécile Niérat, Julien Mayaux, Elise Morawiec, Capucine Morélot-Panzini, Thomas Similowski, Alexandre Demoule, Martin Dres
Early intubation and patient-centered outcomes in septic shock: a secondary analysis of a prospective multicenter study
Ricard Mellado-Artigas, Carlos Ferrando, Frédéric Martino, Agathe Delbove, Bruno L. Ferreyro, Cedric Darreau, Sophie Jacquier, Laurent Brochard, Nicolas Lerolle
Baseline plasma IL-18 may predict simvastatin treatment response in patients with ARDS: a secondary analysis of the HARP-2 randomised clinical trial
Andrew James Boyle, Peter Ferris, Ian Bradbury, John Conlon, Manu Shankar-Hari, Angela J. Rogers, Cecilia M. O’Kane, Daniel F. McAuley
Endarterectomy treatment for patients suffering from a new episode of pulmonary embolism, after screening for chronic thromboembolic pulmonary hypertension
Patrick M. Honore, Sebastien Redant, Pharan Djimafo, Sydney Blackman, Ibrahim Bousbiat, Thierry Preseau, Bogdan Vasile Cismas, Keitiane Kaefer, Leonel Barreto Gutierrez, Sami Anane, Andrea Gallerani, Rachid Attou
An interventional quasi-experimental study to evaluate the impact of a rapid screening strategy in improving control of nosocomial extended-spectrum beta-lactamase-producing Enterobacterales and carbapenemase-producing organisms in critically ill patients
Romain Martischang, Patrice François, Abdessalam Cherkaoui, Gesuele Renzi, Carolina Fankhauser, Jacques Schrenzel, Jérôme Pugin, Stephan Harbarth
Pentraxin-3 as a predictive marker of mortality in sepsis: an updated systematic review and meta-analysis
Guobin Wang, Chunyan Jiang, Junjun Fang, Zhitao Li, Hongliu Cai
Resilience is a dirty word: misunderstood, and how we can truly build it
Mark Z. Y. Tan
Central venous catheterization: the cephalic vein access
Shouyin Jiang, Yehua Shen, Xiaogang Zhao
Lack of SARS-CoV-2-specific cellular response in critically ill COVID-19 patients despite apparent effective vaccination
Frank Bidar, Guillaume Monneret, Franck Berthier, Anne-Claire Lukaszewicz, Fabienne Venet
Recombinant ACE2 protein protects against acute lung injury induced by SARS-CoV-2 spike RBD protein
Lingbing Zhang, Yandan Zhang, Xia Qin, Xuejun Jiang, Jun Zhang, Lejiao Mao, Ziqi Jiang, Yu Jiang, Gang Liu, Jingfu Qiu, Chengzhi Chen, Feng Qiu, Zhen Zou
Reply to: “Hyperoxemia in postsurgical sepsis/septic shock patients is associated with reduced mortality”
Alessandro N. Franciosi, Cormac McCarthy, Ruth MacRedmond
Early versus delayed enteral nutrition in mechanically ventilated patients with circulatory shock: a nested cohort analysis of an international multicenter, pragmatic clinical trial
Luis Ortiz-Reyes, Jayshil J. Patel, Xuran Jiang, Angel Coz Yataco, Andrew G. Day, Faraaz Shah, James Zelten, Maximiliano Tamae-Kakazu, Todd Rice, Daren K. Heyland
Comparison of 6-month outcomes of sepsis versus non-sepsis critically ill patients receiving mechanical ventilation
Carol L. Hodgson, Alisa M. Higgins, Michael Bailey, Jonathon Barrett, Rinaldo Bellomo, D. James Cooper, Belinda J. Gabbe, Theodore Iwashyna, Natalie Linke, Paul S. Myles, Michelle Paton, Steve Philpot, Mark Shulman, Meredith Young, Ary Serpa Neto
The sit-to-stand test as a patient-centered functional outcome for critical care research: a pooled analysis of five international rehabilitation studies
Heather K. O’Grady, Lara Edbrooke, Christopher Farley, Sue Berney, Linda Denehy, Zudin Puthucheary, Michelle E. Kho, Ian Ball, Karen Burns, France Clarke, Deborah Cook, Aileen Costigan, Alison Fox-Robichaud, Ian Gordon, Kimberley Haines, Margaret Herridge, Tim Karachi, Vincent Lo, Alexandra MacDonell, Sunita Mathur, Alexander Molloy, Dale Needham, Amy Pastva, Julie Reid, Bram Rochwerg, Joleen Rose, Jill Rudkowski, Andrew Seely
Impact of dexamethasone on the incidence of ventilator-associated pneumonia in mechanically ventilated COVID-19 patients: a propensity-matched cohort study
Vittorio Scaravilli, Amedeo Guzzardella, Fabiana Madotto, Virginia Beltrama, Antonio Muscatello, Giacomo Bellani, Gianpaola Monti, Massimiliano Greco, Antonio Pesenti, Alessandra Bandera, Giacomo Grasselli
Reply to “Hyperoxemia in postsurgical sepsis/septic shock patients is associated with reduced mortality”
Marta Martín-Fernández, María Heredia-Rodríguez, Eduardo Tamayo
Expert clinical pharmacological advice may make an antimicrobial TDM program for emerging candidates more clinically useful in tailoring therapy of critically ill patients
Milo Gatti, Pier Giorgio Cojutti, Michele Bartoletti, Tommaso Tonetti, Amedeo Bianchini, Stefania Ramirez, Giacinto Pizzilli, Simone Ambretti, Maddalena Giannella, Rita Mancini, Antonio Siniscalchi, Pierluigi Viale, Federico Pea
A dual-center cohort study on the association between early deep sedation and clinical outcomes in mechanically ventilated patients during the COVID-19 pandemic: The COVID-SED study
Robert J. Stephens, Erin M. Evans, Michael J. Pajor, Ryan D. Pappal, Haley M. Egan, Max Wei, Hunter Hayes, Jason A. Morris, Nicholas Becker, Brian W. Roberts, Marin H. Kollef, Nicholas M. Mohr, Brian M. Fuller
Andexanet alfa versus four-factor prothrombin complex concentrate for the reversal of apixaban- or rivaroxaban-associated intracranial hemorrhage: a propensity score-overlap weighted analysis
Olivia S. Costa, Stuart J. Connolly, Mukul Sharma, Jan Beyer-Westendorf, Mary J. Christoph, Belinda Lovelace, Craig I. Coleman
Safety and efficacy of the Seraph® 100 Microbind® Affinity Blood Filter to remove bacteria from the blood stream: results of the first in human study
Gabriele Eden, Julius J. Schmidt, Stefan Büttner, Philipp Kümpers, Carsten Hafer, Alexandros Rovas, Benjamin Florian Koch, Bernhard M. W. Schmidt, Jan T. Kielstein
Mechanisms of lung and diaphragmatic protection by high PEEP in obese COVID-19 ARDS: role of the body mass index
Joaquin Pérez, Javier Hernan Dorado, Emiliano Navarro, Caio C. A. Morais, Matías Accoce
Effect of intravenous clarithromycin in patients with sepsis, respiratory and multiple organ dysfunction syndrome: a randomized clinical trial
Eleni Karakike, Brendon P. Scicluna, Maria Roumpoutsou, Ioannis Mitrou, Niki Karampela, Athanasios Karageorgos, Konstantinos Psaroulis, Eleni Massa, Achillefs Pitsoulis, Panagiotis Chaloulis, Evanthia Pappa, Irene T. Schrijver, Frantzeska Frantzeskaki, Malvina Lada, Nicolas Dauby, David De Bels, Ioannis Floros, Souzana Anisoglou, Eleni Antoniadou, Maria Patrani, Glykeria Vlachogianni, Eleni Mouloudi, Anastasia Antoniadou, David Grimaldi, Thierry Roger, W. Joost Wiersinga, Iraklis Tsangaris, Evangelos J. Giamarellos-Bourboulis
Advanced interventions in the pre-hospital resuscitation of patients with non-compressible haemorrhage after penetrating injuries
E. ter Avest, L. Carenzo, R. A. Lendrum, M. D. Christian, R. M. Lyon, C. Coniglio, M. Rehn, D. J. Lockey, Z. B. Perkins
Driving pressure-guided ventilation decreases the mechanical power compared to predicted body weight-guided ventilation in the Acute Respiratory Distress Syndrome
Anne-Fleur Haudebourg, Samuel Tuffet, François Perier, Keyvan Razazi, Nicolas de Prost, Armand Mekontso Dessap, Guillaume Carteaux
Fluid challenge in critically ill patients receiving haemodynamic monitoring: a systematic review and comparison of two decades
Antonio Messina, Lorenzo Calabrò, Luca Pugliese, Aulona Lulja, Alexandra Sopuch, Daniela Rosalba, Emanuela Morenghi, Glenn Hernandez, Xavier Monnet, Maurizio Cecconi
Validation of survival prediction models for ECMO in Sars-CoV-2-related acute respiratory distress syndrome
Quentin Moyon, Marc Pineton de Chambrun, Guillaume Lebreton, Hédi Chaieb, Alain Combes, Matthieu Schmidt
The PROMIZING trial enrollment algorithm for early identification of patients ready for unassisted breathing
Clement Brault, Jordi Mancebo, Juan-Carlos Suarez Montero, Tracey Bentall, Karen E. A. Burns, Thomas Piraino, François Lellouche, Pierre-Alexandre Bouchard, Emmanuel Charbonney, Guillaume Carteaux, Tommaso Maraffi, Gaëtan Beduneau, Alain Mercat, Yoanna Skrobik, Fei Zuo, Myriam Lafreniere-Roula, Kevin Thorpe, Laurent Brochard, Karen J. Bosma
Lung ultrasound response to awake prone positioning predicts the need for intubation in patients with COVID-19 induced acute hypoxemic respiratory failure: an observational study
Miguel Ibarra-Estrada, María J. Gamero-Rodríguez, Marina García-de-Acilu, Oriol Roca, Laura Sandoval-Plascencia, Guadalupe Aguirre-Avalos, Roxana García-Salcido, Sara A. Aguirre-Díaz, David L. Vines, Sara Mirza, Ramandeep Kaur, Tyler Weiss, Claude Guerin, Jie Li
Key characteristics impacting survival of COVID-19 extracorporeal membrane oxygenation
Johannes Herrmann, Christopher Lotz, Christian Karagiannidis, Steffen Weber-Carstens, Stefan Kluge, Christian Putensen, Andreas Wehrfritz, Karsten Schmidt, Richard K. Ellerkmann, Daniel Oswald, Gösta Lotz, Viviane Zotzmann, Onnen Moerer, Christian Kühn, Matthias Kochanek, Ralf Muellenbach, Matthias Gaertner, Falk Fichtner, Florian Brettner, Michael Findeisen, Markus Heim, Tobias Lahmer, Felix Rosenow, Nils Haake, Philipp M. Lepper, Peter Rosenberger, Stephan Braune, Mirjam Kohls, Peter Heuschmann, Patrick Meybohm, Martha E. Hübsch, Quirin Notz, Daniel Röder, Peter Kranke, Michaela L. Merten, Dominik Jarczak, Kevin Roedl, Jens-Christian Schewe, Stefan F. Ehrentraut, Stefan Kreyer, Ixchel Castellanos, Thorsten Brenner, Frank Herbstreit, Florian Espeter, Jan Wiefhoff, Björn Ellger, Florian J. Raimann, Michael Sonntagbauer, Tobias Wengenmayer, Dawid Staudacher, Ruslan Natanov, Caroline Rolfes, Christian Reyher, Iuliu-Emilian Torje, Patricia Glaser, Vanessa Rembold, Rainer Haseneder, Jan Sackarnd, Johannes Lepper, Andre Becker, Guy Danziger, Carlos Metz, Valbona Mirakaj, Stefanie Calov, Anna Grau, Kirsten Haas, Katrin Ungethüm, Karl Bihlmaier
Correction to: Early versus delayed enteral nutrition in mechanically ventilated patients with circulatory shock: a nested cohort analysis of an international multicenter, pragmatic clinical trial
Luis Ortiz‑Reyes, Jayshil J. Patel, Xuran Jiang, Angel Coz Yataco, Andrew G. Day, Faraaz Shah, James Zelten, Maximiliano Tamae‑Kakazu, Todd Rice, Daren K. Heyland
Prone position improves lung ventilation–perfusion matching in non-intubated COVID-19 patients: a prospective physiologic study
Ling Liu, Jianfeng Xie, Changsong Wang, Zhanqi Zhao, Yang Chong, Xueyan Yuan, Haibo Qiu, Mingyan Zhao, Yi Yang, Arthur S. Slutsky
Spontaneous cyclical fluctuation in respiratory minute volume during prone position ventilation in a patient with COVID-19
Olivier van Minnen, Joep M. Droogh
Response to PEEP in COVID-19 ARDS patients with and without extracorporeal membrane oxygenation. A multicenter case–control computed tomography study
Jean-Christophe Richard, Florian Sigaud, Maxime Gaillet, Maciej Orkisz, Sam Bayat, Emmanuel Roux, Touria Ahaouari, Eduardo Davila, Loic Boussel, Gilbert Ferretti, Hodane Yonis, Mehdi Mezidi, William Danjou, Alwin Bazzani, Francois Dhelft, Laure Folliet, Mehdi Girard, Matteo Pozzi, Nicolas Terzi, Laurent Bitker
An updated HACOR score for predicting the failure of noninvasive ventilation: a multicenter prospective observational study
Jun Duan, Lijuan Chen, Xiaoyi Liu, Suha Bozbay, Yuliang Liu, Ke Wang, Antonio M. Esquinas, Weiwei Shu, Fuxun Yang, Dehua He, Qimin Chen, Bilin Wei, Baixu Chen, Liucun Li, Manyun Tang, Guodan Yuan, Fei Ding, Tao Huang, Zhongxing Zhang, ZhiJun Tang, Xiaoli Han, Lei Jiang, Linfu Bai, Wenhui Hu, Rui Zhang, Bushra Mina
Sepsis subphenotyping based on organ dysfunction trajectory
Zhenxing Xu, Chengsheng Mao, Chang Su, Hao Zhang, Ilias Siempos, Lisa K. Torres, Di Pan, Yuan Luo, Edward J. Schenck, Fei Wang
The obesity paradox for survivors of critically ill patients
Dawei Zhou, Chao Wang, Qing Lin, Tong Li
Dynamics of disease characteristics and clinical management of critically ill COVID-19 patients over the time course of the pandemic: an analysis of the prospective, international, multicentre RISC-19-ICU registry
Pedro David Wendel-Garcia, André Moser, Marie-Madlen Jeitziner, Hernán Aguirre-Bermeo, Pedro Arias-Sanchez, Janina Apolo, Ferran Roche-Campo, Diego Franch-Llasat, Gian-Reto Kleger, Claudia Schrag, Urs Pietsch, Miodrag Filipovic, Sascha David, Klaus Stahl, Souad Bouaoud, Amel Ouyahia, Patricia Fodor, Pascal Locher, Martin Siegemund, Nuria Zellweger, Sara Cereghetti, Peter Schott, Gianfilippo Gangitano, Maddalena Alessandra Wu, Mario Alfaro-Farias, Gerardo Vizmanos-Lamotte, Hatem Ksouri, Nadine Gehring, Emanuele Rezoagli, Fabrizio Turrini, Herminia Lozano-Gómez, Andrea Carsetti, Raquel Rodríguez-García, Bernd Yuen, Anja Baltussen Weber, Pedro Castro, Jesus Oscar Escos-Orta, Alexander Dullenkopf, Maria C. Martín-Delgado, Theodoros Aslanidis, Marie-Helene Perez, Frank Hillgaertner, Samuele Ceruti, Marilene Franchitti Laurent, Julien Marrel, Riccardo Colombo, Marcus Laube, Alberto Fogagnolo, Michael Studhalter, Tobias Wengenmayer, Emiliano Gamberini, Christian Buerkle, Philipp K. Buehler, Stefanie Keiser, Muhammed Elhadi, Jonathan Montomoli, Philippe Guerci, Thierry Fumeaux, Reto A. Schuepbach, Stephan M. Jakob, Yok-Ai Que, Matthias Peter Hilty, Matthias P. Hilty, Pedro Wendel-Garcia, Reto A. Schuepbach, Jonathan Montomoli, Philippe Guerci, Thierry Fumeaux, Souad Bouaoud, Amel Ouyahia, Meriem Abdoun, Mounira Rais, Mario Alfaro-Farias, Gerardo Vizmanos-Lamotte, Angel Caballero, Thomas Tschoellitsch, Jens Meier, Hernán Aguirre-Bermeo, Pedro Arias-Sanchez, Janina Apolo, Luis A. Martinez, Hugo Tirapé-Castro, Islam Galal, Samar Tharwat, Ibrahim Abdehaleem, Geoffrey Jurkolow, Philippe Guerci, Emmanuel Novy, Marie-Reine Losser, Tobias Wengenmayer, Viviane Zotzmann, Sascha David, Klaus Stahl, Benjamin Seeliger, Tobias Welte, Theodoros Aslanidis, Anita Korsos, Luqman Abdulkhudhur Ahmed, Hashim Talib Hashim, Reza Nikandish, Andrea Carsetti, Erika Casarotta, Paolo Giaccaglia, Emanuele Rezoagli, Matteo Giacomini, Aurora Magliocca, Giuliano Bolondi, Antonella Potalivo, Alberto Fogagnolo, Luca Salvi, Maddalena A. Wu, Chiara Cogliati, Riccardo Colombo, Emanuele Catena, Fabrizio Turrini, Maria S. Simonini, Silvia Fabbri, Jonathan Montomoli, Emiliano Gamberini, Gianfilippo Gangitano, Maria M. Bitondo, Francesca Maciopinto, Enrico de Camillis, Marta Venturi, Maria Grazia Bocci, Massimo Antonelli, Arowa Alansari, Abdurraouf Abusalama, Osama Omar, Muhannud Binnawara, Hind Alameen, Muhammed Elhadi, Abdulmueti Alhadi, Ahmed Arhaym, Diederik Gommers, Can Ince, Mustafa Jayyab, Mohammed Alsharif, Raquel Rodríguez-García, Jorge Gámez-Zapata, Xiana Taboada-Fraga, Pedro Castro, Javier Fernandez, Enric Reverter, Arantxa Lander-Azcona, Jesús Escós-Orta, Maria C. Martín-Delgado, Angela Algaba-Calderon, Ferran Roche-Campo, Diego Franch-Llasat, Pablo Concha, Esther Sauras-Colón, Herminia Lozano-Gómez, Begoña Zalba-Etayo, Maria P. Montes, Marc P. Michot, Alexander Klarer, Rolf Ensner, Peter Schott, Severin Urech, Martin Siegemund, Nuria Zellweger, Caroline E. Gebhard, Alexa Hollinger, Lukas Merki, Adriana Lambert, Marcus Laube, Marie M. Jeitziner, Andre Moser, Yok-Ai Que, Stephan M. Jakob, Jan Wiegand, Bernd Yuen, Barbara Lienhardt-Nobbe, Andrea Westphalen, Petra Salomon, Frank Hillgaertner, Marianne Sieber, Alexander Dullenkopf, Giulio Barana, Hatem Ksouri, Govind O. Sridharan, Sara Cereghetti, Filippo Boroli, Jerome Pugin, Serge Grazioli, Christian Bürkle, Julien Marrel, Mirko Brenni, Isabelle Fleisch, Marie-Helene Perez, Anne-Sylvie Ramelet, Anja Baltussen Weber, Peter Gerecke, Andreas Christ, Samuele Ceruti, Andrea Glotta, Maira Biggiogero, Katharina Marquardt, Tobias Hübner, Thomas Neff, Hermann Redecker, Thierry Fumeaux, Mallory Moret-Bochatay, Marco Betello, Friederike Meyer zu Bentrup, Michael Studhalter, Michael Stephan, Nadine Gehring, Daniela Selz, Gian-Reto Kleger, Claudia Schrag, Urs Pietsch, Miodrag Filipovic, Anette Ristic, Antje Heise, Marilene Franchitti Laurent, Jean-Christophe Laurent, Tomislav Gaspert, Christoph Haberthuer, Patricia Fodor, Pascal Locher, Pedro D. Wendel Garcia, Matthias P. Hilty, Reto Schuepbach, Stefanie Keiser, Dorothea Heuberger, Jan Bartussek, Philipp Bühler, Silvio Brugger, Eva-Maria Kleinert, Kim-Jana Fehlbier, Aghyad Danial, Maher Almousa, Yazan Abdulbaki, Kamil Sannah, Elif Colak, Nandor Marczin, Saba Al-Ameri
The future of intensive care: delirium should no longer be an issue
Katarzyna Kotfis, Irene van Diem-Zaal, Shawniqua Williams Roberson, Marek Sietnicki, Mark van den Boogaard, Yahya Shehabi, E. Wesley Ely
Paradoxical response to chest wall loading predicts a favorable mechanical response to reduction in tidal volume or PEEP
John Selickman, Pierre Tawfik, Philip S. Crooke, David J. Dries, Jonathan Shelver, Luciano Gattinoni, John J. Marini
Extravascular lung water levels are associated with mortality: a systematic review and meta-analysis
Francesco Gavelli, Rui Shi, Jean-Louis Teboul, Danila Azzolina, Pablo Mercado, Mathieu Jozwiak, Michelle S. Chew, Wolfgang Huber, Mikhail Y. Kirov, Vsevolod V. Kuzkov, Tobias Lahmer, Manu L. N. G. Malbrain, Jihad Mallat, Samir G. Sakka, Takashi Tagami, Tài Pham, Xavier Monnet
Composition and diversity analysis of the lung microbiome in patients with suspected ventilator-associated pneumonia
Dominic Fenn, Mahmoud I. Abdel-Aziz, Pouline M. P. van Oort, Paul Brinkman, Waqar M. Ahmed, Timothy Felton, Antonio Artigas, Pedro Póvoa, Ignacio Martin-Loeches, Marcus J. Schultz, Paul Dark, Stephen J. Fowler, Lieuwe D. J. Bos, Waqar M. Ahmed, Antonio Artigas Raventos, Jonathan Bannard-Smith, Lieuwe D. J. Bos, Marta Camprubi, Luis Coelho, Paul Dark, Alan Davie, Emili Diaz, Gemma Goma, Timothy Felton, Stephen J. Fowler, Royston Goodacre, Craig Johnson, Hugo Knobel, Oluwasola Lawal, Jan-Hendrik Leopold, Ignacio Martin-Loeches, Tamara M. E. Nijsen, Pouline M. P. van Oort, Pedro Povoa, Nicholas J. W. Rattray, Guus Rijnders, Marcus J. Schultz, Ruud Steenwelle, Peter J. Sterk, Jordi Valles, Fred Verhoeckx, Anton Vink, Hans Weda, Iain R. White, Tineke Winters, Tetyana Zakharkina
Intravenous IgM-enriched immunoglobulins in critical COVID-19: a multicentre propensity-weighted cohort study
Tim Rahmel, Felix Kraft, Helge Haberl, Ute Achtzehn, Timo Brandenburger, Holger Neb, Dominik Jarczak, Maximilian Dietrich, Harry Magunia, Frieda Zimmer, Jale Basten, Claudia Landgraf, Thea Koch, Kai Zacharowski, Markus A. Weigand, Peter Rosenberger, Roman Ullrich, Patrick Meybohm, Axel Nierhaus, Detlef Kindgen-Milles, Nina Timmesfeld, Michael Adamzik
Development and validation of a multivariable prediction model of central venous catheter-tip colonization in a cohort of five randomized trials
Jeanne Iachkine, Niccolò Buetti, Harm-Jan de Grooth, Anaïs R. Briant, Olivier Mimoz, Bruno Mégarbane, Jean-Paul Mira, Stéphane Ruckly, Bertrand Souweine, Damien du Cheyron, Leonard A. Mermel, Jean-François Timsit, Jean-Jacques Parienti
Gasdermin-D activation by SARS-CoV-2 triggers NET and mediate COVID-19 immunopathology
Camila Meirelles S. Silva, Carlos Wagner S. Wanderley, Flavio Protasio Veras, Augusto Velozo Gonçalves, Mikhael Haruo Fernandes Lima, Juliana Escher Toller-Kawahisa, Giovanni Freitas Gomes, Daniele Carvalho Nascimento, Valter V. Silva Monteiro, Isadora Marques Paiva, Cícero José Luíz Ramos Almeida, Diego Brito Caetité, Juliana Costa Silva, Maria Isabel Fernandes Lopes, Letícia Pastorelli Bonjorno, Marcela Cavichioli Giannini, Natalia Brasil Amaral, Maíra Nilson Benatti, Rodrigo Carvalho Santana, Luis Eduardo Alves Damasceno, Bruna Manuella Souza Silva, Ayda Henriques Schneider, Icaro Maia Santos Castro, Juan Carlo Santos Silva, Amanda Pereira Vasconcelos, Tiago Tomazini Gonçalves, Sabrina Setembre Batah, Tamara Silva Rodrigues, Victor Ferreira Costa, Marjorie Cornejo Pontelli, Ronaldo B. Martins, Timna Varela Martins, Danillo Lucas Alves Espósito, Guilherme Cesar Martelossi Cebinelli, Benedito Antônio Lopes da Fonseca, Luiz Osório Silveira Leiria, Larissa Dias Cunha, Eurico Arruda, Helder I. Nakaia, Alexandre Todorovic Fabro, Rene D. R. Oliveira, Dario S. Zamboni, Paulo Louzada-Junior, Thiago Mattar Cunha, José Carlos Farias Alves-Filho, Fernando Queiroz Cunha
Comparison of diagnostic criteria for acute kidney injury in critically ill children: a multicenter cohort study
Yuxian Kuai, Min Li, Jiao Chen, Zhen Jiang, Zhenjiang Bai, Hui Huang, Lin Wei, Ning Liu, Xiaozhong Li, Guoping Lu, Yanhong Li
Extended prone positioning duration for COVID-19-related ARDS: benefits and detriments
Thaïs Walter, Noémie Zucman, Jimmy Mullaert, Ingrid Thiry, Coralie Gernez, Damien Roux, Jean-Damien Ricard
Disparities in adult critical care resources across Pakistan: findings from a national survey and assessment using a novel scoring system
Mustafa Ali Khan, Hamna Shahbaz, Ali Aahil Noorali, Anam Noor Ehsan, Mareeha Zaki, Fahham Asghar, Mohammed Moizul Hassan, Haroon Muhammad Arshad, Muhammad Sohaib, Muhammad Ali Asghar, Muhammad Faisal Khan, Amber Sabeen, Masooma Aqeel, Muhammad Haroon Khan, Tahir Munir, Syed Kashif Amin, Huba Atiq, Adil Hussain Haider, Zainab Samad, Asad Latif
Integrated PERSEVERE and endothelial biomarker risk model predicts death and persistent MODS in pediatric septic shock: a secondary analysis of a prospective observational study
Mihir R. Atreya, Natalie Z. Cvijanovich, Julie C. Fitzgerald, Scott L. Weiss, Michael T. Bigham, Parag N. Jain, Adam J. Schwarz, Riad Lutfi, Jeffrey Nowak, Geoffrey L. Allen, Neal J. Thomas, Jocelyn R. Grunwell, Torrey Baines, Michael Quasney, Bereketeab Haileselassie, Christopher J. Lindsell, Matthew N. Alder, Hector R. Wong
Effects of PEEP on regional ventilation-perfusion mismatch in the acute respiratory distress syndrome
Bertrand Pavlovsky, Antonio Pesenti, Elena Spinelli, Gaetano Scaramuzzo, Ines Marongiu, Paola Tagliabue, Savino Spadaro, Giacomo Grasselli, Alain Mercat, Tommaso Mauri
Comment to “Very late intubation in COVID-19 patients: A forgotten prognosis factor?”
Ricard Mellado-Artigas, Luigi Zattera, Enric Barbeta, Carlos Ferrando
The gut–liver axis in sepsis: interaction mechanisms and therapeutic potential
Xue Zhang, Hong Liu, Kenji Hashimoto, Shiying Yuan, Jiancheng Zhang
Oxygenation versus driving pressure for determining the best positive end-expiratory pressure in acute respiratory distress syndrome
Saida Rezaiguia-Delclaux, Léo Ren, Aurélie Gruner, Calypso Roman, Thibaut Genty, François Stéphan
External validation of a machine learning model to predict hemodynamic instability in intensive care unit
Chiang Dung-Hung, Tian Cong, Jiang Zeyu, Ou-Yang Yu-Shan, Lin Yung-Yan
The ABCDE approach to difficult weaning from venoarterial extracorporeal membrane oxygenation
Christiaan L. Meuwese, Daniel Brodie, Dirk W. Donker
Neurologic manifestations of COVID-19 in critically ill patients: results of the prospective multicenter registry PANDEMIC
Konstantinos Dimitriadis, Jan Meis, Hermann Neugebauer, Kristian Barlinn, Bernhard Neumann, Georg Gahn, Piergiorgio Lochner, Benjamin Knier, Sarah Lindemann, Kurt Wolfram Sühs, Kristina Szabo, Thomas Pfefferkorn, Ingo Schirotzek, Tobias Freilinger, Bassa Burc, Albrecht Günther, Matthias Wittstock, Patrick Schramm, Gernot Reimann, Jana Godau, Gabor Nagy, Fatima B. Koenig, Fabian Essig, Hartwig Klinker, Christian Hartmann, Moritz L. Schmidbauer, Tim Steinberg, Lora Lefterova, Christina Klose, Julian Bösel
Improving the intensive care experience from the perspectives of different stakeholders
Jos M. Latour, Nancy Kentish-Barnes, Theresa Jacques, Marc Wysocki, Elie Azoulay, Victoria Metaxa
Tidal volume challenge to predict preload responsiveness in patients with acute respiratory distress syndrome under prone position
Rui Shi, Soufia Ayed, Francesca Moretto, Danila Azzolina, Nello De Vita, Francesco Gavelli, Simone Carelli, Arthur Pavot, Christopher Lai, Xavier Monnet, Jean-Louis Teboul
Feasibility and discriminatory value of tissue motion annular displacement in sepsis-induced cardiomyopathy: a single-center retrospective observational study
Jieqiong Song, Yao Yao, Shilong Lin, Yizhou He, Duming Zhu, Ming Zhong
Palliative care practice and moral distress during COVID-19 pandemic (PEOpLE-C19 study): a national, cross-sectional study in intensive care units in the Czech Republic
Tereza Prokopová, Jan Hudec, Kamil Vrbica, Jan Stašek, Andrea Pokorná, Petr Štourač, Kateřina Rusinová, Paulína Kerpnerová, Radka Štěpánová, Adam Svobodník, Jan Maláska, Jan Maláska, Kateřina Rusinová, David Černý, Jozef Klučka, Andrea Pokorná, Miroslav Světlák, František Duška, Milan Kratochvíl, Alena Slezáčková, Milan Kratochvíl, Petr Štourač, Tomáš Gabrhelík, Josef Kuře, Daniel Suk, Tomáš Doležal, Tereza Prokopová, Jana Čerňanová, Kamil Vrbica, Klára Fabiánková, Eva Straževská, Jan Hudec
Are we ready to think differently about setting PEEP?
Matthew E. Cove, Michael R. Pinsky, John J. Marini
Long-term cognitive functioning is impaired in ICU-treated COVID-19 patients: a comprehensive controlled neuropsychological study
Henriikka Ollila, Riikka Pihlaja, Sanna Koskinen, Annamari Tuulio-Henriksson, Viljami Salmela, Marjaana Tiainen, Laura Hokkanen, Johanna Hästbacka
Noninvasive ventilation in COVID-19 patients aged ≥ 70 years—a prospective multicentre cohort study
Kamil Polok, Jakub Fronczek, Antonio Artigas, Hans Flaatten, Bertrand Guidet, Dylan W. De Lange, Jesper Fjølner, Susannah Leaver, Michael Beil, Sigal Sviri, Raphael Romano Bruno, Bernhard Wernly, Bernardo Bollen Pinto, Joerg C. Schefold, Dorota Studzińska, Michael Joannidis, Sandra Oeyen, Brian Marsh, Finn H. Andersen, Rui Moreno, Maurizio Cecconi, Christian Jung, Wojciech Szczeklik, Philipp Eller, Michael Joannidis, Dieter Mesotten, Pascal Reper, Sandra Oeyen, Walter Swinnen, Helene Brix, Jens Brushoej, Maja Villefrance, Helene Korvenius Nedergaard, Anders Thais Bjerregaard, Ida Riise Balleby, Kasper Andersen, Maria Aagaard Hansen, Stine Uhrenholt, Helle Bundgaard, Jesper Fjølner, Aliae A. R. Mohamed Hussein, Rehab Salah, Yasmin Khairy NasrEldin Mohamed Ali, Kyrillos Wassim, Yumna A. Elgazzar, Samar Tharwat, Ahmed Y. Azzam, Ayman abdelmawgoad habib, Hazem Maarouf Abosheaishaa, Mohammed A. Azab, Susannah Leaver, Arnaud Galbois, Bertrand Guidet, Cyril Charron, Emmanuel Guerot, Guillaume Besch, Jean-Philippe Rigaud, Julien Maizel, Michel Djibré, Philippe Burtin, Pierre Garcon, Saad Nseir, Xavier Valette, Nica Alexandru, Nathalie Marin, Marie Vaissiere, Gaëtan Plantefeve, Thierry Vanderlinden, Igor Jurcisin, Buno Megarbane, Anais Caillard, Arnaud Valent, Marc Garnier, Sebastien Besset, Johanna Oziel, Jean-herlé RAPHALEN, Stéphane Dauger, Guillaume Dumas, Bruno Goncalves, Gaël Piton, Eberhard Barth, Ulrich Goebel, Eberhard Barth, Anselm Kunstein, Michael Schuster, Martin Welte, Matthias Lutz, Patrick Meybohm, Stephan Steiner, Tudor Poerner, Hendrik Haake, Stefan Schaller, Stefan Schaller, Stefan Schaller, Detlef Kindgen-Milles, Christian Meyer, Muhammed Kurt, Karl Friedrich Kuhn, Winfried Randerath, Jakob Wollborn, Zouhir Dindane, Hans-Joachim Kabitz, Ingo Voigt, Gonxhe Shala, Andreas Faltlhauser, Nikoletta Rovina, Zoi Aidoni, Evangelia Chrisanthopoulou, Antonios Papadogoulas, Mohan Gurjar, Ata Mahmoodpoor, Abdullah khudhur Ahmed, Brian Marsh, Ahmed Elsaka, Sigal Sviri, Vittoria Comellini, Ahmed Rabha, Hazem Ahmed, Silvio A. Namendys-Silva, Abdelilah Ghannam, Martijn Groenendijk, Marieke Zegers, Dylan de Lange, Alex Cornet, Mirjam Evers, Lenneke Haas, Tom Dormans, Willem Dieperink, Luis Romundstad, Britt Sjøbø, Finn H. Andersen, Hans Frank Strietzel, Theresa Olasveengen, Michael Hahn, Miroslaw Czuczwar, Ryszard Gawda, Jakub Klimkiewicz, Maria de Lurdes Campos Santos, André Gordinho, Henrique Santos, Rui Assis, Ana Isabel Pinho Oliveira, Mohamed Raafat Badawy, David Perez-Torres, Gemma Gomà, Mercedes Ibarz Villamayor, Angela Prado Mira, Patricia Jimeno Cubero, Susana Arias Rivera, Teresa Tomasa, David Iglesias, Eric Mayor Vázquez, Cesar Aldecoa, Aida Fernández Ferreira, Begoña Zalba-Etayo, Isabel Canas-Perez, Luis Tamayo-Lomas, Cristina Diaz-Rodriguez, Susana Sancho, Jesús Priego, Enas M. Y. Abualqumboz, Momin Majed Yousuf Hilles, Mahmoud Saleh, Nawfel Ben-HAmouda, Andrea Roberti, Alexander Dullenkopf, Yvan Fleury, Bernardo Bollen Pinto, Joerg C. Schefold, Mohammed Al-Sadawi
Acute kidney injury in critical COVID-19: a multicenter cohort analysis in seven large hospitals in Belgium
Hannah Schaubroeck, Wim Vandenberghe, Willem Boer, Eva Boonen, Bram Dewulf, Camille Bourgeois, Jasperina Dubois, Alexander Dumoulin, Tom Fivez, Jan Gunst, Greet Hermans, Piet Lormans, Philippe Meersseman, Dieter Mesotten, Björn Stessel, Marc Vanhoof, Greet De Vlieger, Eric Hoste
Optimizing PO2 during peripheral veno-arterial ECMO: a narrative review
Hadrien Winiszewski, Pierre-Grégoire Guinot, Matthieu Schmidt, Guillaume Besch, Gael Piton, Andrea Perrotti, Roberto Lorusso, Antoine Kimmoun, Gilles Capellier
The impact of extracorporeal membrane oxygenation on the exposure to isavuconazole: a plea for thorough pharmacokinetic evaluation
Beatrijs Mertens, Joost Wauters, Yves Debaveye, Niels Van Regenmortel, Karlien Degezelle, Philippe Meersseman, Greet Hermans, Christophe Vandenbriele, Ruth Van Daele, Isabel Spriet
Clustering identifies endotypes of traumatic brain injury in an intensive care cohort: a CENTER-TBI study
Cecilia A. I. Åkerlund, Anders Holst, Nino Stocchetti, Ewout W. Steyerberg, David K. Menon, Ari Ercole, David W. Nelson, Cecilia Åkerlund, Krisztina Amrein, Nada Andelic, Lasse Andreassen, Audny Anke, Anna Antoni, Gérard Audibert, Philippe Azouvi, Maria Luisa Azzolini, Ronald Bartels, Pál Barzó, Romuald Beauvais, Ronny Beer, Bo-Michael Bellander, Antonio Belli, Habib Benali, Maurizio Berardino, Luigi Beretta, Morten Blaabjerg, Peter Bragge, Alexandra Brazinova, Vibeke Brinck, Joanne Brooker, Camilla Brorsson, Andras Buki, Monika Bullinger, Manuel Cabeleira, Alessio Caccioppola, Emiliana Calappi, Maria Rosa Calvi, Peter Cameron, Guillermo Carbayo Lozano, Marco Carbonara, Simona Cavallo, Giorgio Chevallard, Arturo Chieregato, Giuseppe Citerio, Hans Clusmann, Mark Coburn, Jonathan Coles, Jamie D. Cooper, Marta Correia, Amra Čović, Nicola Curry, Endre Czeiter, Marek Czosnyka, Claire DahyotFizelier, Paul Dark, Helen Dawes, Véronique De Keyser, Vincent Degos, Francesco Della Corte, Hugo den Boogert, Bart Depreitere, Đula Đilvesi, Abhishek Dixit, Emma Donoghue, Jens Dreier, GuyLoup Dulière, Ari Ercole, Patrick Esser, Erzsébet Ezer, Martin Fabricius, Valery L. Feigin, Kelly Foks, Shirin Frisvold, Alex Furmanov, Pablo Gagliardo, Damien Galanaud, Dashiell Gantner, Guoyi Gao, Pradeep George, Alexandre Ghuysen, Lelde Giga, Ben Glocker, Jagoš Golubovic, Pedro A. Gomez, Johannes Gratz, Benjamin Gravesteijn, Francesca Grossi, Russell L. Gruen, Deepak Gupta, Juanita A. Haagsma, Iain Haitsma, Raimund Helbok, Eirik Helseth, Lindsay Horton, Jilske Huijben, Peter J. Hutchinson, Bram Jacobs, Stefan Jankowski, Mike Jarrett, Jiyao Jiang, Faye Johnson, Kelly Jones, Mladen Karan, Angelos G. Kolias, Erwin Kompanje, Daniel Kondziella, Evgenios Kornaropoulos, LarsOwe Koskinen, Noémi Kovács, Ana Kowark, Alfonso Lagares, Linda Lanyon, Steven Laureys, Fiona Lecky, Didier Ledoux, Rolf Lefering, Valerie Legrand, Aurelie Lejeune, Leon Levi, Roger Lightfoot, Hester Lingsma, Andrew I. R. Maas, Ana M. CastañoLeón, Marc Maegele, Marek Majdan, Alex Manara, Geoffrey Manley, Costanza Martino, Hugues Maréchal, Julia Mattern, Catherine McMahon, Béla Melegh, David Menon, Tomas Menovsky, Ana Mikolic, Benoit Misset, Visakh Muraleedharan, Lynnette Murray, Ancuta Negru, David Nelson, Virginia Newcombe, Daan Nieboer, József Nyirádi, Otesile Olubukola, Matej Oresic, Fabrizio Ortolano, Aarno Palotie, Paul M. Parizel, JeanFrançois Payen, Natascha Perera, Vincent Perlbarg, Paolo Persona, Wilco Peul, Anna Piippo-Karjalainen, Matti Pirinen, Dana Pisica, Horia Ples, Suzanne Polinder, Inigo Pomposo, Jussi P. Posti, Louis Puybasset, Andreea Radoi, Arminas Ragauskas, Rahul Raj, Malinka Rambadagalla, Isabel Retel Helmrich, Jonathan Rhodes, Sylvia Richardson, Sophie Richter, Samuli Ripatti, Saulius Rocka, Cecilie Roe, Olav Roise, Jonathan Rosand, Jeffrey V. Rosenfeld, Christina Rosenlund, Guy Rosenthal, Rolf Rossaint, Sandra Rossi, Daniel Rueckert, Martin Rusnák, Juan Sahuquillo, Oliver Sakowitz, Renan SanchezPorras, Janos Sandor, Nadine Schäfer, Silke Schmidt, Herbert Schoechl, Guus Schoonman, Rico Frederik Schou, Elisabeth Schwendenwein, Charlie Sewalt, Ranjit D. Singh, Toril Skandsen, Peter Smielewski, Abayomi Sorinola, Emmanuel Stamatakis, Simon Stanworth, Robert Stevens, William Stewart, Ewout W. Steyerberg, Nino Stocchetti, Nina Sundström, Riikka Takala, Viktória Tamás, Tomas Tamosuitis, Mark Steven Taylor, Braden Te Ao, Olli Tenovuo, Alice Theadom, Matt Thomas, Dick Tibboel, Marjolein Timmers, Christos Tolias, Tony Trapani, Cristina Maria Tudora, Andreas Unterberg, Peter Vajkoczy, Shirley Vallance, Egils Valeinis, Zoltán Vámos, Mathieu van der Jagt, Gregory Van der Steen, Joukje van der Naalt, Jeroen T. J. M. van Dijck, Inge A. van Erp, Thomas A. van Essen, Wim Van Hecke, Caroline van Heugten, Dominique Van Praag, Ernest van Veen, Thijs Vande Vyvere, Roel P. J. van Wijk, Alessia Vargiolu, Emmanuel Vega, Kimberley Velt, Jan Verheyden, Paul M. Vespa, Anne Vik, Rimantas Vilcinis, Victor Volovici, Nicole von Steinbüchel, Daphne Voormolen, Petar Vulekovic, Kevin K. W. Wang, Daniel Whitehouse, Eveline Wiegers, Guy Williams, Lindsay Wilson, Stefan Winzeck, Stefan Wolf, Zhihui Yang, Peter Ylén, Alexander Younsi, Frederick A. Zeiler, Veronika Zelinkova, Agate Ziverte, Tommaso Zoerle
A randomized, placebo-controlled, double-blinded pilot study of angiotensin 1–7 (TXA-127) for the treatment of severe COVID-19
Gebhard Wagener, Monica P. Goldklang, Adam Gerber, Katerina Elisman, Katherine A. Eiseman, Laura D. Fonseca, Jeanine M. D’Armiento
Intravenous vitamin C in adults with sepsis in the intensive care unit: still LOV’IT?
Christian Stoppe, Jean-Charles Preiser, Daniel de Backer, Gunnar Elke
Influence of temperature management at 33 °C versus normothermia on survival in patients with vasopressor support after out-of-hospital cardiac arrest: a post hoc analysis of the TTM-2 trial
Joachim Düring, Martin Annborn, Alain Cariou, Michelle S. Chew, Josef Dankiewicz, Hans Friberg, Matthias Haenggi, Zana Haxhija, Janus C. Jakobsen, Halvor Langeland, Fabio Silvio Taccone, Matthew Thomas, Susann Ullén, Matt P. Wise, Niklas Nielsen
Capnodynamic monitoring of lung volume and blood flow in response to increased positive end-expiratory pressure in moderate to severe COVID-19 pneumonia: an observational study
Luis Schulz, Antony Stewart, William O’Regan, Peter McCanny, Danielle Austin, Magnus Hallback, Mats Wallin, Anders Aneman
Early steroids and ventilator-associated pneumonia in COVID-19-related ARDS
Pauline Lamouche-Wilquin, Jérôme Souchard, Morgane Pere, Matthieu Raymond, Pierre Asfar, Cédric Darreau, Florian Reizine, Baptiste Hourmant, Gwenhaël Colin, Guillaume Rieul, Pierre Kergoat, Aurélien Frérou, Julien Lorber, Johann Auchabie, Béatrice La Combe, Philippe Seguin, Pierre-Yves Egreteau, Jean Morin, Yannick Fedun, Emmanuel Canet, Jean-Baptiste Lascarrou, Agathe Delbove
Why compliance and driving pressure may be inappropriate targets for PEEP setting during ARDS
Domenico Luca Grieco, Filippo Bongiovanni, Antonio M. Dell’Anna, Massimo Antonelli
Outcomes after extracorporeal life support for COVID-19 myocarditis: an analysis of the Extracorporeal Life Support Organization Registry
Joseph E. Tonna, Chuen Seng Tan, Kasia Hryniewicz, Ryan P. Barbaro, Daniel Brodie, Graeme MacLaren
Co-infection and ICU-acquired infection in COVID-19 ICU patients: a secondary analysis of the UNITE-COVID data set
Andrew Conway Morris, Katharina Kohler, Thomas De Corte, Ari Ercole, Harm-Jan De Grooth, Paul W. G. Elbers, Pedro Povoa, Rui Morais, Despoina Koulenti, Sameer Jog, Nathan Nielsen, Alasdair Jubb, Maurizio Cecconi, Jan De Waele, Marco Bezzi, Alicia Gira, Philipp Eller, Tarikul Hamid, Injamam Ull Haque, Wim De Buyser, Antonella Cudia, Daniel De Backer, Pierre Foulon, Vincent Collin, Jan De Waele, Jolien Van Hecke, Elisabeth De Waele, Claire Van Malderen, Jean-Baptiste Mesland, Michael Piagnerelli, Lionel Haentjens, Nicolas De Schryver, Jan Van Leemput, Philippe Vanhove, Pierre Bulpa, Viktoria Ilieva, David Katz, Anna Geagea, Alexandra Binnie, Fernando Tirapegui, Gustavo Lago, Jerónimo Graf, Rodrigo Perez-Araos, Patricio Vargas, Felipe Martinez, Eduardo Labarca, Daniel Molano Franco, Daniela Parra-Tanoux, Luis Felipe Reyes, David Yepes, Filip Periš, Sanda Stojanović Stipić, Cynthia Vanessa Campozano Burgos, Paulo Roberto Navas Boada, Jose Luis Barberan Brun, Juan Pablo Paredes Ballesteros, Ahmed Hammouda, Omar Elmandouh, Ahmed Azzam, Aliae Mohamed Hussein, Islam Galal, Ahmed K. Awad, Mohammed A. Azab, Maged Abdalla, Hebatallah Assal, Mostafa Alfishawy, Sherief Ghozy, Samar Tharwat, Abdullah Eldaly, Veronika Reinhard, Anne Chrisment, Chrystelle Poyat, Julio Badie, Fernando Berdaguer Ferrari, Björn Weiss, Karl Friedrich Kuhn, Julius J. Grunow, Marco Lorenz, Stefan Schaller, Peter Spieth, Marc Bota, Falk Fichtner, Kristina Fuest, Tobias Lahmer, Johannes Herrmann, Patrick Meybohm, Nikolaos Markou, Georgia Vasileiadou, Evangelia Chrysanthopoulou, Panagiotis Papamichalis, Ioanna Soultati, Sameer Jog, Kushal Kalvit, Sheila Nainan Myatra, Ivan Krupa, Aisa Tharwat, Alistair Nichol, Aine McCarthy, Ata Mahmoodpoor, Tommaso Tonetti, Paolo Isoni, Savino Spadaro, Carlo Alberto Volta, Lucia Mirabella, Alberto Noto, Gaetano Florio, Amedeo Guzzardella, Chiara Paleari, Federica Baccanelli, Marzia Savi, Massimo Antonelli, Barbara Vaccarini, Giorgia Montrucchio, Gabriele Sales, Katia Donadello, Leonardo Gottin, Enrico Polati, Silvia De Rosa, Demet Sulemanji, Abdurraouf Abusalama, Muhammed Elhadi, Montelongo Felipe De Jesus, Daniel Rodriguez Gonzalez, Nancy Canedo, Alejandro Esquivel Chavez, Tarek Dendane, Bart Grady, Ben de Jong, Eveline van der Heiden, Patrick Thoral, Bas van den Bogaard, Peter E. Spronk, Sefanja Achterberg, Melanie Groeneveld, Ralph K. L. So, Calvin de Wijs, Harm Scholten, Albertus Beishuizen, Alexander D. Cornet, Auke C. Reidinga, Hetty Kranen, Roos Mensink, Sylvia den Boer, Marcel de Groot, Oliver Beck, Carina Bethlehem, Bas van Bussel, Tim Frenzel, Celestine de Jong, Rob Wilting, Jozef Kesecioglu, Jannet Mehagnoul-Schipper, Datonye Alasia, Ashok Kumar, Ahad Qayyum, Muhammad Rana, Mustafa Abu Jayyab, Rosario Quispe Sierra, Aaron Mark Hernandez, Lúcia Taborda, Tiago Ramires, Catarina Silva, Carolina Roriz, Pedro Póvoa, Patricia Patricio, Maria Lurdes Santos, Vasco Costa, Pedro Cunha, Celina Gonçalves, Sandra Nunes, João Camões, Diana Adrião, Ana Oliveira, Ali Omrani, Muna Al Maslamani, Abdurrahmaan Suei elbuzidi, Bara Mahmoud Al qudah, Abdel Rauof Akkari, Mohamed Alkhatteb, Anas Baiou, Ahmed Husain, Mohamed Alwraidat, Ibrahim Abdulsalam Saif, Dana Bakdach, Amna Ahmed, Mohamed Aleef, Awadh Bintaher, Cristina Petrisor, Evgeniy Popov, Ksenia Popova, Mariia Dementienko, Boris Teplykh, Alexey Pyregov, Liubov Davydova, Belskii Vladislav, Elena Neporada, Ivan Zverev, Svetlana Meshchaninova, Dmitry Sokolov, Elena Gavrilova, Irena Shlyk, Igor Poliakov, Mapинa Bлacoвa, Ohoud Aljuhani, Amina Alkhalaf, Felwa Bin Humaid, Yaseen Arabi, Ahmed Kuhail, Omar Elrabi, Madihah Alghnam, Amit Kansal, Vui Kian Ho, Jensen Ng, Raquel Rodrígez García, Xiana Taboada Fraga, Mª del Pilar García-Bonillo, Antonio Padilla-Serrano, Marta Martin Cuadrado, Carlos Ferrando, Ignacio Catalan-Monzon, Laura Galarza, Fernando Frutos-Vivar, Jorge Jimenez, Carmen Rodríguez-Solis, Enric Franquesa-Gonzalez, Guillermo Pérez Acosta, Luciano Santana Cabrera, Juan Pablo Aviles Parra, Francisco Muñoyerro Gonzalez, Maria del Carmen Lorente Conesa, Ignacio Yago Martinez Varela, Orville Victoriano Baez Pravia, Maria Cruz Martin Delgado, Carlos Munoz de Cabo, Ana-Maria Ioan, Cesar Perez-Calvo, Arnoldo Santos, Ane Abad-Motos, Javier Ripolles-Melchor, Belén Civantos Martin, Santiago Yus Teruel, Juan Higuera Lucas, Aaron Blandino Ortiz, Raúl de Pablo Sánchez, Jesús Emilio Barrueco-Francioni, Lorena Forcelledo Espina, José M. Bonell-Goytisolo, Iñigo Salaverria, Antonia Socias Mir, Emilio Rodriguez-Ruiz, Virginia Hidalgo Valverde, Patricia Jimeno Cubero, Francisca Arbol Linde, Nieves Cruza Leganes, Juan Maria Romeu, Pablo Concha, José Angel Berezo-Garcia, Virginia Fraile, Cristina Cuenca-Rubio, David Perez-Torres, Ainhoa Serrano, Clara Martínez Valero, Andrea Ortiz Suner, Leire Larrañaga, Noemi Legaristi, Gerardo Ferrigno, Safa Khlafalla, Rosita Bihariesingh-Sanchit, Frank Zoerner, Jonathan Grip, Kristina Kilsand, Jonas Österlind, Magnus von Seth, Johan Berkius, Samuele Ceruti, Andrea Glotta, Seval Izdes, Işıl Özkoçak Turan, Ahmet Cosar, Burcin Halacli, Necla Dereli, Mehmet Yilmaz, Türkay Akbas, Gülseren Elay, Selin Eyüpoğlu, Yelíz Bílír, Kemal Tolga Saraçoğlu, Ebru Kaya, Ayca Sultan Sahin, Pervin Korkmaz Ekren, Tuğçe Mengi, Kezban Ozmen Suner, Yakup Tomak, Ahmet Eroglu, Asad Alsabbah, Katie Hanlon, Kevin Gervin, Sean McMahon, Samantha Hagan, Caroline V. Higenbottam, Randeep Mullhi, Lottie Poulton, Tomasz Torlinski, Allen Gareth, Nick Truman, Gopal Vijayakumar, Chris Hall, Alasdair Jubb, Lenka Cagova, Nicola Jones, Sam Graham, Nicole Robin, Amanda Cowton, Adrian Donnelly, Natalia Singatullina, Melanie Kent, Carole Boulanger, Zoë Campbell, Elizabeth Potter, Natalie Duric, Tamas Szakmany, Orinta Kviatkovske, Nandor Marczin, Caroline Ellis, Rajnish Saha, Chunda Sri-Chandana, John Allan, Lana Mumelj, Harish Venkatesh, Vera Nina Gotz, Anthony Cochrane, Nuttha Lumlertgul, Barbara Ficial, Susan Jain, Giulia Beatrice Crapelli, Aikaterini Vlachou, David Golden, Sweyn Garrioch, Jeremy Henning, Gupta Loveleena, Miriam Davey, Lina Grauslyte, Erika Salciute-Simene, Martin Cook, Danny Barling, Phil Broadhurst, Sarah Purvis, Spivey Michael, Benjamin Shuker, Irina Grecu, Daniel Harding, Natalia Singatullina, James T. Dean, Nathan D. Nielsen, Sama Al-Bayati, Mohammed Al-Sadawi, Mariane Charron, Peter Stubenrauch, Jairo Santanilla, Catherine Wentowski, Dorothea Rosenberger, Polikseni Eksarko, Randeep Jawa
Muscular myostatin gene expression and plasma concentrations are decreased in critically ill patients
Julius J. Grunow, Katja Reiher, Niklas M. Carbon, Lilian Jo Engelhardt, Knut Mai, Susanne Koch, Joerg C. Schefold, Werner Z’Graggen, Stefan J. Schaller, Jens Fielitz, Joachim Spranger, Steffen Weber-Carstens, Tobias Wollersheim
Clarithromycin as an immunomodulator in sepsis: still a (IN)CLASS act
Timothy Arthur Chandos Snow, Antonio Cesar, Mervyn Singer, Nishkantha Arulkumaran
Time-varying intensity of oxygen exposure is associated with mortality in critically ill patients with mechanical ventilation
Zhu Zhu, Mingqin Zhou, Yao Wei, Hui Chen
Core outcome measures for clinical effectiveness trials of nutritional and metabolic interventions in critical illness: an international modified Delphi consensus study evaluation (CONCISE)
T. W. Davies, R. J. J. van Gassel, M. van de Poll, J. Gunst, M. P. Casaer, K. B. Christopher, J. C. Preiser, A. Hill, K. Gundogan, A. Reintam-Blaser, A. F. Rousseau, C. Hodgson, D. M. Needham, M. Castro, S. Schaller, T. McClelland, J. J. Pilkington, C. M. Sevin, P. E. Wischmeyer, Z. Y. Lee, D. Govil, A. Li, L. Chapple, L. Denehy, J. C. Montejo-González, B. Taylor, D. E. Bear, R. Pearse, A. McNelly, J. Prowle, Z. A. Puthucheary
Development of clinical phenotypes and biological profiles via proteomic analysis of trauma patients
Jotaro Tachino, Hisatake Matsumoto, Fuminori Sugihara, Shigeto Seno, Daisuke Okuzaki, Tetsuhisa Kitamura, Sho Komukai, Yoshiyuki Kido, Takashi Kojima, Yuki Togami, Yusuke Katayama, Yuko Nakagawa, Hiroshi Ogura
Unshrinking the baby lung to calm the VILI vortex
Gary Nieman, Michaela Kollisch-Singule, Harry Ramcharran, Joshua Satalin, Sarah Blair, Louis A. Gatto, Penny Andrews, Auyon Ghosh, David W. Kaczka, Donald Gaver, Jason Bates, Nader M. Habashi
Clinical validation of a multiplex droplet digital PCR for diagnosing suspected bloodstream infections in ICU practice: a promising diagnostic tool
Jing Wu, Bin Tang, Yuzhen Qiu, Ruoming Tan, Jialin Liu, Jiang Xia, Jing Zhang, Jingjing Huang, Jieming Qu, Jingyong Sun, Xiaoli Wang, Hongping Qu
The impact of acquired coagulation factor XIII deficiency in traumatic bleeding and wound healing
Christian Kleber, Armin Sablotzki, Sebastian Casu, Martin Olivieri, Kai-Martin Thoms, Johannes Horter, Felix C. F. Schmitt, Ingvild Birschmann, Dietmar Fries, Marc Maegele, Herbert Schöchl, Michaela Wilhelmi
Clinical sepsis phenotypes in critically ill COVID-19 patients
Niklas Bruse, Emma J. Kooistra, Aron Jansen, Rombout B. E. van Amstel, Nicolette F. de Keizer, Jason N. Kennedy, Christopher Seymour, Lonneke A. van Vught, Peter Pickkers, Matthijs Kox
The importance of instrumental assessment in disorders of consciousness: a comparison between American, European, and UK International recommendations
F. G. Magnani, F. Barbadoro, M. Cacciatore, M. Leonardi
A new perspective on NO pathway in sepsis and ADMA lowering as a potential therapeutic approach
Jaipal Singh, Young Lee, John A. Kellum
Bedside assessment of left atrial pressure in critical care: a multifaceted gem
Emma Maria Bowcock, Anthony Mclean
Interviews with primary care physicians identify unmet transition needs after ICU
Katrina E. Hauschildt, Rachel K. Hechtman, Hallie C. Prescott, Leigh M. Cagino, Theodore J. Iwashyna
Correction: Co-infection and ICU-acquired infection in COVID-19 ICU patients: a secondary analysis of the UNITE-COVID data set
Andrew Conway Morris, Katharina Kohler, Thomas De Corte, Ari Ercole, Harm-Jan De Grooth, Paul W. G. Elbers, Pedro Povoa, Rui Morais, Despoina Koulenti, Sameer Jog, Nathan Nielsen, Alasdair Jubb, Maurizio Cecconi, Jan De Waele, Marco Bezzi, Alicia Gira, Philipp Eller, Tarikul Hamid, Injamam Ull Haque, Wim De Buyser, Antonella Cudia, Daniel De Backer, Pierre Foulon, Vincent Collin, Jan De Waele, Jolien Van Hecke, Elisabeth De Waele, Claire Van Malderen, Jean-Baptiste Mesland, Michael Piagnerelli, Lionel Haentjens, Nicolas De Schryver, Jan Van Leemput, Philippe Vanhove, Pierre Bulpa, Viktoria Ilieva, David Katz, Anna Geagea, Alexandra Binnie, Fernando Tirapegui, Gustavo Lago, Jerónimo Graf, Rodrigo Perez-Araos, Patricio Vargas, Felipe Martinez, Eduardo Labarca, Daniel Molano Franco, Daniela Parra-Tanoux, Luis Felipe Reyes, David Yepes, Filip Periš, Sanda Stojanović Stipić, Cynthia Vanessa Campozano Burgos, Paulo Roberto Navas Boada, Jose Luis Barberan Brun, Juan Pablo Paredes Ballesteros, Ahmed Hammouda, Omar Elmandouh, Ahmed Azzam, Aliae Mohamed Hussein, Islam Galal, Ahmed K. Awad, Mohammed A. Azab, Maged Abdalla, Hebatallah Assal, Mostafa Alfishawy, Sherief Ghozy, Samar Tharwat, Abdullah Eldaly, Veronika Reinhard, Anne Chrisment, Chrystelle Poyat, Julio Badie, Fernando Berdaguer Ferrari, Björn Weiss, Karl Friedrich Kuhn, Julius J. Grunow, Marco Lorenz, Stefan Schaller, Peter Spieth, Marc Bota, Falk Fichtner, Kristina Fuest, Tobias Lahmer, Johannes Herrmann, Patrick Meybohm, Nikolaos Markou, Georgia Vasileiadou, Evangelia Chrysanthopoulou, Panagiotis Papamichalis, Ioanna Soultati, Sameer Jog, Kushal Kalvit, Sheila Nainan Myatra, Ivan Krupa, Aisa Tharwat, Alistair Nichol, Aine McCarthy, Ata Mahmoodpoor, Tommaso Tonetti, Paolo Isoni, Savino Spadaro, Carlo Alberto Volta, Lucia Mirabella, Alberto Noto, Gaetano Florio, Amedeo Guzzardella, Chiara Paleari, Federica Baccanelli, Marzia Savi, Massimo Antonelli, Barbara Vaccarini, Giorgia Montrucchio, Gabriele Sales, Katia Donadello, Leonardo Gottin, Enrico Polati, Silvia De Rosa, Demet Sulemanji, Abdurraouf Abusalama, Muhammed Elhadi, Montelongo Felipe De Jesus, Daniel Rodriguez Gonzalez, Nancy Canedo, Alejandro Esquivel Chavez, Tarek Dendane, Bart Grady, Ben de Jong, Eveline van der Heiden, Patrick Thoral, Bas van den Bogaard, Peter E. Spronk, Sefanja Achterberg, Melanie Groeneveld, Ralph K. L. So, Calvin de Wijs, Harm Scholten, Albertus Beishuizen, Alexander D. Cornet, Auke C. Reidinga, Hetty Kranen, Roos Mensink, Sylvia den Boer, Marcel de Groot, Oliver Beck, Carina Bethlehem, Bas van Bussel, Tim Frenzel, Celestine de Jong, Rob Wilting, Jozef Kesecioglu, Jannet Mehagnoul-Schipper, Datonye Alasia, Ashok Kumar, Ahad Qayyum, Muhammad Rana, Mustafa Abu Jayyab, Rosario Quispe Sierra, Aaron Mark Hernandez, Lúcia Taborda, Tiago Ramires, Catarina Silva, Carolina Roriz, Pedro Póvoa, Patricia Patricio, Maria Lurdes Santos, Vasco Costa, Pedro Cunha, Celina Gonçalves, Sandra Nunes, João Camões, Diana Adrião, Ana Oliveira, Ali Omrani, Muna Al Maslamani, Abdurrahmaan Suei elbuzidi, Bara Mahmoud Al qudah, Abdel Rauof Akkari, Mohamed Alkhatteb, Anas Baiou, Ahmed Husain, Mohamed Alwraidat, Ibrahim Abdulsalam Saif, Dana Bakdach, Amna Ahmed, Mohamed Aleef, Awadh Bintaher, Cristina Petrisor, Evgeniy Popov, Ksenia Popova, Mariia Dementienko, Boris Teplykh, Alexey Pyregov, Liubov Davydova, Belskii Vladislav, Elena Neporada, Ivan Zverev, Svetlana Meshchaninova, Dmitry Sokolov, Elena Gavrilova, Irena Shlyk, Igor Poliakov, Mapинa Bлacoвa, Ohoud Aljuhani, Amina Alkhalaf, Felwa Bin Humaid, Yaseen Arabi, Ahmed Kuhail, Omar Elrabi, Madihah Alghnam, Amit Kansal, Vui Kian Ho, Jensen Ng, Raquel Rodrígez García, Xiana Taboada Fraga, Mª del Pilar García-Bonillo, Antonio Padilla-Serrano, Marta Martin Cuadrado, Carlos Ferrando, Ignacio Catalan-Monzon, Laura Galarza, Fernando Frutos-Vivar, Jorge Jimenez, Carmen Rodríguez-Solis, Enric Franquesa-Gonzalez, Guillermo Pérez Acosta, Luciano Santana Cabrera, Juan Pablo Aviles Parra, Francisco Muñoyerro Gonzalez, Maria del Carmen Lorente Conesa, Ignacio Yago Martinez Varela, Orville Victoriano Baez Pravia, Maria Cruz Martin Delgado, Carlos Munoz de Cabo, Ana-Maria Ioan, Cesar Perez-Calvo, Arnoldo Santos, Ane Abad-Motos, Javier Ripolles-Melchor, Belén Civantos Martin, Santiago Yus Teruel, Juan Higuera Lucas, Aaron Blandino Ortiz, Raúl de Pablo Sánchez, Jesús Emilio Barrueco-Francioni, Lorena Forcelledo Espina, José M. Bonell-Goytisolo, Iñigo Salaverria, Antonia Socias Mir, Emilio Rodriguez-Ruiz, Virginia Hidalgo Valverde, Patricia Jimeno Cubero, Francisca Arbol Linde, Nieves Cruza Leganes, Juan Maria Romeu, Pablo Concha, José Angel Berezo-Garcia, Virginia Fraile, Cristina Cuenca-Rubio, David Perez-Torres, Ainhoa Serrano, Clara Martínez Valero, Andrea Ortiz Suner, Leire Larrañaga, Noemi Legaristi, Gerardo Ferrigno, Safa Khlafalla, Rosita Bihariesingh-Sanchit, Frank Zoerner, Jonathan Grip, Kristina Kilsand, Jonas Österlind, Magnus von Seth, Johan Berkius, Samuele Ceruti, Andrea Glotta, Seval Izdes, Işıl Özkoçak Turan, Ahmet Cosar, Burcin Halacli, Necla Dereli, Mehmet Yilmaz, Türkay Akbas, Gülseren Elay, Selin Eyüpoğlu, Yelíz Bílír, Kemal Tolga Saraçoğlu, Ebru Kaya, Ayca Sultan Sahin, Pervin Korkmaz Ekren, Tuğçe Mengi, Kezban Ozmen Suner, Yakup Tomak, Ahmet Eroglu, Asad Alsabbah, Katie Hanlon, Kevin Gervin, Sean McMahon, Samantha Hagan, Caroline V. Higenbottam, Randeep Mullhi, Lottie Poulton, Tomasz Torlinski, Allen Gareth, Nick Truman, Gopal Vijayakumar, Chris Hall, Alasdair Jubb, Lenka Cagova, Nicola Jones, Sam Graham, Nicole Robin, Amanda Cowton, Adrian Donnelly, Natalia Singatullina, Melanie Kent, Carole Boulanger, Zoë Campbell, Elizabeth Potter, Natalie Duric, Tamas Szakmany, Orinta Kviatkovske, Nandor Marczin, Caroline Ellis, Rajnish Saha, Chunda Sri-Chandana, John Allan, Lana Mumelj, Harish Venkatesh, Vera Nina Gotz, Anthony Cochrane, Nuttha Lumlertgul, Barbara Ficial, Susan Jain, Giulia Beatrice Crapelli, Aikaterini Vlachou, David Golden, Sweyn Garrioch, Jeremy Henning, Gupta Loveleena, Miriam Davey, Lina Grauslyte, Erika Salciute-Simene, Martin Cook, Danny Barling, Phil Broadhurst, Sarah Purvis, Spivey Michael, Benjamin Shuker, Irina Grecu, Daniel Harding, Natalia Singatullina, James T. Dean, Nathan D. Nielsen, Sama Al-Bayati, Mohammed Al-Sadawi, Mariane Charron, Peter Stubenrauch, Jairo Santanilla, Catherine Wentowski, Dorothea Rosenberger, Polikseni Eksarko, Randeep Jawa
The central and biodynamic role of gut microbiota in critically ill patients
Hannah Wozniak, Tal Sarah Beckmann, Lorin Fröhlich, Tania Soccorsi, Christophe Le Terrier, Aude de Watteville, Jacques Schrenzel, Claudia-Paula Heidegger
Subphenotypes in acute kidney injury: a narrative review
Suvi T. Vaara, Pavan K. Bhatraju, Natalja L. Stanski, Blaithin A. McMahon, Kathleen Liu, Michael Joannidis, Sean M. Bagshaw
Effect of invasive mechanical ventilation on the diversity of the pulmonary microbiota
Chang Liu, Kang Wu, Tianyu Sun, Bin Chen, Yaxing Yi, Ruotong Ren, Lixin Xie, Kun Xiao
Using real-time visualization system for data-driven decision support to achieve lung protective strategy: a retrospective observational study
How-Yang Tseng, Chieh-Lung Chen, Yu-Chao Lin, Ming-Che Chuang, Wu-Huei Hsu, Wan-Yun Hsiao, Tung-Mei Chen, Min-Tzu Wang, Wei-Chun Huang, Chih-Yu Chen, Biing-Ru Wu, Chih-Yen Tu, Shinn-Jye Liang, Wei-Cheng Chen
Correction: Using arterial-venous oxygen difference to guide red blood cell transfusion strategy
Alberto Fogagnolo, Fabio Silvio Taccone, Jean Louis Vincent, Giulia Benetto, Elaine Cavalcante, Elisabetta Marangoni, Riccardo Ragazzi, Jacques Creteur, Carlo Alberto Volta, Savino Spadaro
A Bayesian reanalysis of the Standard versus Accelerated Initiation of Renal-Replacement Therapy in Acute Kidney Injury (STARRT-AKI) trial
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Cobb, Cassidy Codan, Caitriona Cody, Alexandra Coelho, Megan Coles, Gwenhaël Colin, Michael Collins, Sebastiano Maria Colombo, Pamela Combs, Marie Connor, Anne Conrad, Sofía Contreras, Elaine Conway, Graham S. Cooke, Mary Copland, Hugues Cordel, Amanda Corley, Sabine Cornelis, Alexander Daniel Cornet, Arianne Joy Corpuz, Andrea Cortegiani, Grégory Corvaisier, Emma Costigan, Camille Couffignal, Sandrine Couffin-Cadiergues, Roxane Courtois, Stéphanie Cousse, Rachel Cregan, Sabine Croonen, Gloria Crowl, Jonathan Crump, Claudina Cruz, Juan Luis Cruz Bermúdez, Jaime Cruz Rojo, Marc Csete, Ailbhe Cullen, Ger Curley, Elodie Curlier, Colleen Curran, Paula Custodio, Ana da Silva Filipe, Charlene Da Silveira, Al-Awwab Dabaliz, Andrew Dagens, Darren Dahly, Heidi Dalton, Jo Dalton, Seamus Daly, Juliana Damas, Nick Daneman, Corinne Daniel, Emmanuelle A. Dankwa, Jorge Dantas, Frédérick D’Aragon, Gillian de Loughry, Diego de Mendoza, Etienne De Montmollin, Rafael Freitas de Oliveira França, Ana Isabel de Pinho Oliveira, Rosanna De Rosa, Thushan de Silva, Peter de Vries, Jillian Deacon, David Dean, Alexa Debard, Marie-Pierre Debray, Nathalie DeCastro, William Dechert, Lauren Deconninck, Romain Decours, Eve Defous, Isabelle Delacroix, Eric Delaveuve, Karen Delavigne, Andrea Dell’Amore, Pierre Delobel, Corine Delsing, Elisa Demonchy, Emmanuelle Denis, Dominique Deplanque, Pieter Depuydt, Diane Descamps, Mathilde Desvallées, Santi Dewayanti, Pathik Dhanger, Alpha Diallo, Sylvain Diamantis, André Dias, Juan Jose Diaz, Priscila Diaz, Kévin Didier, Jean-Luc Diehl, Wim Dieperink, Jérôme Dimet, Vincent Dinot, Fara Diop, Alphonsine Diouf, Yael Dishon, Félix Djossou, Annemarie B. Docherty, Helen Doherty, Arjen M. Dondorp, Christl A. Donnelly, Maria Donnelly, Chloe Donohue, Sean Donohue, Yoann Donohue, Peter Doran, Céline Dorival, Eric D’Ortenzio, James Joshua Douglas, Nathalie Dournon, Triona Downer, Joanne Downey, Mark Downing, Tom Drake, Aoife Driscoll, Claudio Duarte Fonseca, Vincent Dubee, François Dubos, Alexandre Ducancelle, Susanne Dudman, Paul Dunand, Jake Dunning, Mathilde Duplaix, Emanuele Durante-Mangoni, Lucian Durham III, Bertrand Dussol, Juliette Duthoit, Xavier Duval, Anne Margarita Dyrhol-Riise, Marco Echeverria-Villalobos, Siobhan Egan, Carla Eira, Mohammed El Sanharawi, Subbarao Elapavaluru, Brigitte Elharrar, Jacobien Ellerbroek, Philippine Eloy, Tarek Elshazly, Isabelle Enderle, Tomoyuki Endo, Ilka Engelmann, Vincent Enouf, Olivier Epaulard, Martina Escher, Mariano Esperatti, Hélène Esperou, Catarina Espírito Santo, Marina Esposito-Farese, João Estevão, Manuel Etienne, Nadia Ettalhaoui, Anna Greti Everding, Mirjam Evers, Isabelle Fabre, Marc Fabre, Amna Faheem, Arabella Fahy, Cameron J. Fairfield, Zul Fakar, Komal Fareed, Pedro Faria, Ahmed Farooq, Arie Zainul Fatoni, Karine Faure, Raphaël Favory, Mohamed Fayed, Niamh Feely, Laura Feeney, Jorge Fernandes, Marília Andreia Fernandes, Susana Fernandes, François-Xavier Ferrand, Eglantine Ferrand Devouge, Joana Ferrão, Mário Ferraz, Benigno Ferreira, Bernardo Ferreira, Isabel Ferreira, Sílvia Ferreira, Ricard Ferrer-Roca, Nicolas Ferriere, Céline Ficko, Juan Fiorda, Thomas Flament, Clara Flateau, Tom Fletcher, Letizia Lucia Florio, Deirdre Flynn, Claire Foley, Jean Foley, Victor Fomin, Tatiana Fonseca, Patricia Fontela, Simon Forsyth, Denise Foster, Giuseppe Foti, Erwan Fourn, Marianne Fraher, Diego Franch-Llasat, Christophe Fraser, John F. Fraser, Marcela Vieira Freire, Ana Freitas Ribeiro, Craig French, Caren Friedrich, Stéphanie Fry, Nora Fuentes, Masahiro Fukuda, Argin G, Valérie Gaborieau, Rostane Gaci, Massimo Gagliardi, Jean-Charles Gagnard, Amandine Gagneux-Brunon, Sérgio Gaião, Linda Gail Skeie, Phil Gallagher, Carrol Gamble, Arthur Garan, Rebekha Garcia, Noelia García Barrio, Navya Garimella, Denis Garot, Valérie Garrait, Basanta Gauli, Nathalie Gault, Aisling Gavin, Anatoliy Gavrylov, Alexandre Gaymard, Johannes Gebauer, Eva Geraud, Louis Gerbaud Morlaes, Nuno Germano, Jade Ghosn, Marco Giani, Jess Gibson, Tristan Gigante, Morgane Gilg, Elaine Gilroy, Guillermo Giordano, Michelle Girvan, Valérie Gissot, Daniel Glikman, Petr Glybochko, Eric Gnall, Geraldine Goco, François Goehringer, Siri Goepel, Jean-Christophe Goffard, Jonathan Golob, Joan Gómez-Junyent, Marie Gominet, Alicia Gonzalez, Patricia Gordon, Isabelle Gorenne, Laure Goubert, Cécile Goujard, Tiphaine Goulenok, Margarite Grable, Jeronimo Graf, Edward Wilson Grandin, Pascal Granier, Giacomo Grasselli, Christopher A. Green, Courtney Greene, William Greenhalf, Segolène Greffe, Domenico Luca Grieco, Matthew Griffee, Fiona Griffiths, Albert Groenendijk, Anja Grosse Lordemann, Heidi Gruner, Yusing Gu, Jérémie Guedj, Martin Guego, Dewi Guellec, Anne-Marie Guerguerian, Daniela Guerreiro, Romain Guery, Anne Guillaumot, Laurent Guilleminault, Maisa Guimarães de Castro, Thomas Guimard, Marieke Haalboom, Daniel Haber, Hannah Habraken, Ali Hachemi, Nadir Hadri, Fakhir Haidri, Sheeba Hakak, Adam Hall, Matthew Hall, Sophie Halpin, Jawad Hameed, Ansley Hamer, Rebecca Hamidfar, Terese Hammond, Rashan Haniffa, Hayley Hardwick, Ewen M. Harrison, Janet Harrison, Samuel Bernard Ekow Harrison, Mohd Shahnaz Hasan, Junaid Hashmi, Muhammad Hayat, Ailbhe Hayes, Leanne Hays, Jan Heerman, Lars Heggelund, Ross Hendry, Martina Hennessy, Maxime Hentzien, Andrew Hershey, Liv Hesstvedt, Astarini Hidayah, Dawn Higgins, Eibhilin Higgins, Rupert Higgins, Rita Hinchion, Samuel Hinton, Hikombo Hitoto, Antonia Ho, Alexandre Hoctin, Isabelle Hoffmann, Oscar Hoiting, Rebecca Holt, Jan Cato Holter, Peter Horby, Juan Pablo Horcajada, Koji Hoshino, Kota Hoshino, Ikram Houas, Catherine L. Hough, Jimmy Ming-Yang Hsu, Jean-Sébastien Hulot, Stella Huo, Abby Hurd, Iqbal Hussain, Samreen Ijaz, Arfan Ikram, Hajnal-Gabriela Illes, Patrick Imbert, Mohammad Imran, Rana Imran Sikander, Aftab Imtiaz, Hugo Inácio, Carmen Infante Dominguez, Mariachiara Ippolito, Sarah Isgett, Tiago Isidoro, Margaux Isnard, Daniel Ivulich, Danielle Jaafar, Salma Jaafoura, Julien Jabot, Clare Jackson, Nina Jamieson, Pierre Jaquet, Coline Jaud-Fischer, Stéphane Jaureguiberry, Florence Jego, Synne Jenum, Ruth N. Jorge García, Cédric Joseph, Mark Joseph, Swosti Joshi, Mercé Jourdain, Philippe Jouvet, Anna Jung, Dafsah Juzar, Ouifiya Kafif, Florentia Kaguelidou, Sabina Kali, Smaragdi Kalomoiri, Darshana Hewa Kandamby, Chris Kandel, Darakhshan Kanwal, Anant Kataria, Kevin Katz, Christy Kay, Hannah Keane, Seán Keating, Andrea Kelly, Aoife Kelly, Claire Kelly, Niamh Kelly, Sadie Kelly, Yvelynne Kelly, Maeve Kelsey, Kalynn Kennon, Maeve Kernan, Younes Kerroumi, Sharma Keshav, Imrana Khalid, Osama Khalid, Antoine Khalil, Coralie Khan, Irfan Khan, Quratul Ain Khan, Sushil Khanal, Abid Khatak, Amin Khawaja, Michelle E. Kho, Saye Khoo, Nasir Khoso, Yuri Kida, Peter Kiiza, Beathe Kiland Granerud, Anders Benjamin Kildal, Antoine Kimmoun, Detlef Kindgen-Milles, Nobuya Kitamura, Paul Klenerman, Rob Klont, Gry Kloumann Bekken, Stephen R. Knight, Robin Kobbe, Chamira Kodippily, Malte Kohns Vasconcelos, Sabin Koirala, Caroline Kosgei, Arsène Kpangon, Karolina Krawczyk, Oksana Kruglova, Deepali Kumar, Mukesh Kumar, Bharath Kumar Tirupakuzhi Vijayaraghavan, Pavan Kumar Vecham, Dinesh Kuriakose, Ethan Kurtzman, Demetrios Kutsogiannis, Galyna Kutsyna, Konstantinos Kyriakoulis, Marie Lachatre, Marie Lacoste, John G. 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Luna, Liem Luong, Nestor Luque, Dominique Luton, Nilar Lwin, Ruth Lyons, Olavi Maasikas, Oryane Mabiala, Moïse Machado, Sara Machado, Gabriel Macheda, Hashmi Madiha, Guillermo Maestro de la Calle, Rafael Mahieu, Sophie Mahy, Ana Raquel Maia, Lars S. Maier, Mylène Maillet, Thomas Maitre, Maximilian Malfertheiner, Nadia Malik, Paddy Mallon, Fernando Maltez, Denis Malvy, Victoria Manda, Laurent Mandelbrot, Julie Mankikian, Edmund Manning, Aldric Manuel, Ceila Maria Sant, Ana Malaque, Daniel Marino, Flávio Marino, Samuel Markowicz, Ana Marques, Catherine Marquis, Brian Marsh, Laura Marsh, Megan Marshal, Celina Turchi Martelli, Emily Martin, Guillaume Martin-Blondel, Martin Martinot, Ana Martins, João Martins, Nuno Martins, Caroline Martins Rego, Gennaro Martucci, Olga Martynenko, Eva Miranda Marwali, David Maslove, Sabina Mason, Sobia Masood, Basri Mat Nor, Basri Mat Nor, Moshe Matan, Meghena Mathew, Daniel Mathieu, Mathieu Mattei, Romans Matulevics, Laurence Maulin, Michael Maxwell, Javier Maynar, Thierry Mazzoni, Natalie Mc Evoy, Lisa Mc Sweeney, Colin McArthur, Colin McArthur, Aine McCarthy, Anne McCarthy, Colin McCloskey, Rachael McConnochie, Sherry McDermott, Sarah E. McDonald, Aine McElroy, Samuel McElwee, Victoria McEneany, Allison McGeer, Chris McKay, Johnny McKeown, Kenneth A. McLean, Paul McNally, Bairbre McNicholas, Elaine McPartlan, Edel Meaney, Cécile Mear-Passard, Maggie Mechlin, Minahel Atif, Maqsood Meher, Ferruccio Mele, Luis Melo, Kashif Memon, Joao Joao Mendes, Ogechukwu Menkiti, Kusum Menon, France Mentré, Alexander J. Mentzer, Emmanuelle Mercier, Noémie Mercier, Antoine Merckx, Mayka Mergeay-Fabre, Blake Mergler, António Mesquita, Osama Metwally, Agnès Meybeck, Dan Meyer, Alison M. Meynert, Vanina Meysonnier, Amina Meziane, Mehdi Mezidi, Céline Michelanglei, Isabelle Michelet, Vladislav Mihnovit, Asma Moin, David Molina, Elena Molinos, Brenda Molloy, Mary Mone, Agostinho Monteiro, Claudia Montes, Giorgia Montrucchio, Sarah Moore, Shona C. Moore, Lina Morales Cely, Lucia Moro, Catherine Motherway, Ana Motos, Hugo Mouquet, Clara Mouton Perrot, Julien Moyet, Aisha Kalsoom Mufti, Jimmy Mullaert, Fredrik Müller, Karl Erik Müller, Daniel Munblit, Syed Muneeb, Nadeem Munir, Aisling Murphy, Aisling Murphy, Lorna Murphy, Marlène Murris, Himed Musaab, Himasha Muvindi, Dimitra Melia Myrodia, Farah Nadia Mohd-Hanafiah, Dave Nagpal, Alex Nagrebetsky, Nageswaran Narayanan, Rashid Nasim Khan, Alasdair Nazerali-Maitland, Nadège Neant, Nikita Nekliudov, Raul Neto, Emily Neumann, Pauline Yeung Ng, Anthony Nghi, Duc Nguyen, Orna Ni Choileain, Niamh Ni Leathlobhair, Prompak Nitayavardhana, Stephanie Nonas, Marion Noret, Lisa Norman, Alessandra Notari, Mahdad Noursadeghi, Adam Nowinski, Saad Nseir, Jose I. Nunez, Nurnaningsih Nurnaningsih, Elsa Nyamankolly, Fionnuala O. Brien, Annmarie O. Callaghan, Annmarie O’Callaghan, Giovanna Occhipinti, Derbrenn OConnor, Max O’Donnell, Tawnya Ogston, Takayuki Ogura, Sophie O’Halloran, Katie O’Hearn, João Oliveira, Larissa Oliveira, David S. Y. Ong, Wilna Oosthuyzen, Anne Opavsky, Peter Openshaw, Saijad Orakzai, Claudia Milena Orozco-Chamorro, Jamel Ortoleva, Javier Osatnik, Linda O’Shea, Miriam O’Sullivan, Nadia Ouamara, Rachida Ouissa, Eric Oziol, Maïder Pagadoy, Justine Pages, Amanda Palacios, Mario Palacios, Massimo Palmarini, Giovanna Panarello, Hem Paneru, Mauro Panigada, Nathalie Pansu, Aurélie Papadopoulos, Rachael Parke, Melissa Parker, Briseida Parra, Taha Pasha, Jérémie Pasquier, Bruno Pastene, Fabian Patauner, Luís Patrão, Patricia Patricio, Juliette Patrier, Lisa Patterson, Rajyabardhan Pattnaik, Christelle Paul, Mical Paul, Jorge Paulos, William A. Paxton, Jean-François Payen, Florent Peelman, Nathan Peiffer-Smadja, Vincent Peigne, Mare Pejkovska, Paolo Pelosi, Ithan D. Peltan, Rui Pereira, Daniel Perez, Luis Periel, Thomas Perpoint, Antonio Pesenti, Vincent Pestre, Lenka Petrou, Michele Petrovic, Ventzislava Petrov-Sanchez, Frank Olav Pettersen, Gilles Peytavin, Scott Pharand, Walter Picard, Olivier Picone, Carola Pierobon, Djura Piersma, Carlos Pimentel, Raquel Pinto, Catarina Pires, Isabelle Pironneau, Lionel Piroth, Riinu Pius, Laurent Plantier, Julien Poissy, Ryadh Pokeerbux, Sergio Poli, Georgios Pollakis, Diane Ponscarme, Andra-Maris Post, Douwe F. Postma, Pedro Povoa, Diana Póvoas, Jeff Powis, Sofia Prapa, Sébastien Preau, Christian Prebensen, Jean-Charles Preiser, Anton Prinssen, Mark G. 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Russell, Maeve Ryan, Maria Ryan, Steffi Ryckaert, Aleksander Rygh Holten, Isabela Saba, Sairah Sadaf, Musharaf Sadat, Valla Sahraei, Nadia Saidani, Maximilien Saint-Gilles, Pranya Sakiyalak, Nawal Salahuddin, Leonardo Salazar, Jodat Saleem, Gabriele Sales, Stéphane Sallaberry, Charlotte Salmon Gandonniere, Hélène Salvator, Olivier Sanchez, Angel Sanchez-Miralles, Vanessa Sancho-Shimizu, Gyan Sandhu, Zulfiqar Sandhu, Pierre-François Sandrine, Oana Sandulescu, Marlene Santos, Shirley Sarfo-Mensah, Bruno Sarmento Banheiro, Benjamine Sarton, Sree Satyapriya, Rumaisah Satyawati, Egle Saviciute, Justin Schaffer, Tjard Schermer, Arnaud Scherpereel, Marion Schneider, Stephan Schroll, Michael Schwameis, Janet T. Scott, James Scott-Brown, Nicholas Sedillot, Tamara Seitz, Jaganathan Selvanayagam, Caroline Semaille, Malcolm G. 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Yun Tang, Xiaobo Yang, Yuan Yu, Huaqing Shu, Yin Yuan, Hong Liu, Xiaojing Zou, Shiying Yuan, You Shang
Mortality of patients with hospital-onset sepsis in hospitals with all-day and non-all-day rapid response teams: a prospective nationwide multicenter cohort study
Dong-gon Hyun, Su Yeon Lee, Jee Hwan Ahn, Jin Won Huh, Sang-Bum Hong, Younsuck Koh, Chae-Man Lim, Dong Kyu Oh, Gee Young Suh, Kyeongman Jeon, Ryoung-Eun Ko, Young-Jae Cho, Yeon Joo Lee, Sung Yoon Lim, Sunghoon Park, Jeongwon Heo, Jae-myeong Lee, Kyung Chan Kim, Yeon Joo Lee, Youjin Chang, Kyeongman Jeon, Sang-Min Lee, Suk-Kyung Hong, Woo Hyun Cho, Sang Hyun Kwak, Heung Bum Lee, Jong-Joon Ahn, Gil Myeong Seong, Song-I Lee, Sunghoon Park, Tai Sun Park, Su Hwan Lee, Eun Young Choi, Jae Young Moon
Myocardial effects of angiotensin II compared to norepinephrine in an animal model of septic shock
Bruno Garcia, Fuhong Su, Laurence Dewachter, Raphaël Favory, Amina Khaldi, Alexander Moiroux-Sahraoui, Filippo Annoni, Francisco Vasques-Nóvoa, Estela Rocha-Oliveira, Roberto Roncon-Albuquerque Jr, Geraldine Hubesch, Hassane Njimi, Jean-Louis Vincent, Fabio S. Taccone, Jacques Creteur, Antoine Herpain
Adverse events, short- and long-term outcomes of extra corporeal liver therapy in the intensive care unit: 16 years experience with MARS® in a single center
Clément Monet, Audrey De Jong, Yassir Aarab, Lauranne Piron, Albert Prades, Julie Carr, Fouad Belafia, Gérald Chanques, Boris Guiu, Georges-Philippe Pageaux, Samir Jaber
Obesity and critical care nutrition: current practice gaps and directions for future research
Roland N. Dickerson, Laura Andromalos, J. Christian Brown, Maria Isabel T. D. Correia, Wanda Pritts, Emma J. Ridley, Katie N. Robinson, Martin D. Rosenthal, Arthur R. H. van Zanten
A mobile isolator that eases the life of ICU staffs during COVID-19
Linghua Yu, Feng Han
Correction to: The future of intensive care: delirium should no longer be an issue
Katarzyna Kotfis, Irene van Diem‑Zaal, Shawniqua Williams Roberson, Marek Sietnicki, Mark van den Boogaard, Yahya Shehabi, E. Wesley Ely
Brain tissue oxygen tension: Is it a derivative of arterial blood?
Gurgen Harutyunyan, Varsenik Harutyunyan Jaghatspanyan, Emma Martirosyan, Rosa Isabel Benitez Bermejo, Garnik Harutyunyan, Andrés Sánchez Gimeno, Pau Ignasi García Zapata, Armen Varosyan, Suren Soghomonyan
A novel capnogram analysis to guide ventilation during cardiopulmonary resuscitation: clinical and experimental observations
Arnaud Lesimple, Caroline Fritz, Alice Hutin, Emmanuel Charbonney, Dominique Savary, Stéphane Delisle, Paul Ouellet, Gilles Bronchti, Fanny Lidouren, Thomas Piraino, François Beloncle, Nathan Prouvez, Alexandre Broc, Alain Mercat, Laurent Brochard, Renaud Tissier, Jean-Christophe Richard
Assessing oral comprehension with an eye tracking based innovative device in critically ill patients and healthy volunteers: a cohort study
Laetitia Bodet-Contentin, Hélène Messet-Charrière, Valérie Gissot, Aurélie Renault, Grégoire Muller, Aurélie Aubrey, Pierrick Gadrez, Elsa Tavernier, Stephan Ehrmann
Critical care hepatology: definitions, incidence, prognosis and role of liver failure in critically ill patients
Aritz Perez Ruiz de Garibay, Andreas Kortgen, Julia Leonhardt, Alexander Zipprich, Michael Bauer
Cryoprecipitate transfusion in trauma patients attenuates hyperfibrinolysis and restores normal clot structure and stability: Results from a laboratory sub-study of the FEISTY trial
Gael B. Morrow, Timea Feller, Zoe McQuilten, Elizabeth Wake, Robert A. S. Ariëns, James Winearls, Nicola J. Mutch, Mike A. Laffan, Nicola Curry
Publisher Correction to: Discomfort improvement for critically ill patients using electronic relaxation devices: results of the cross‑over randomized controlled trial E‑CHOISIR (Electronic‑CHOIce of a System for Intensive care Relaxation)
Lili Merliot‑Gailhoustet, Chloé Raimbert, Océane Garnier, Julie Carr, Audrey De Jong, Nicolas Molinari, Samir Jaber, Gerald Chanques
Relationship between corticosteroid use and incidence of ventilator-associated pneumonia in COVID-19 patients: a retrospective multicenter study
Ouriel Saura, Anahita Rouzé, Ignacio Martin-Loeches, Pedro Povoa, Louis Kreitmann, Antoni Torres, Matthieu Metzelard, Damien Du Cheyron, Fabien Lambiotte, Fabienne Tamion, Marie Labruyere, Claire Boulle Geronimi, Charles-Edouard Luyt, Martine Nyunga, Olivier Pouly, Arnaud W. Thille, Bruno Megarbane, Anastasia Saade, Eleni Magira, Jean-François Llitjos, Iliana Ioannidou, Alexandre Pierre, Jean Reignier, Denis Garot, Jean-Luc Baudel, Guillaume Voiriot, Gaëtan Plantefeve, Elise Morawiec, Pierre Asfar, Alexandre Boyer, Armand Mekontso-Dessap, Fotini Bardaka, Emili Diaz, Christophe Vinsonneau, Pierre-Edouard Floch, Nicolas Weiss, Adrian Ceccato, Antonio Artigas, David Nora, Alain Duhamel, Julien Labreuche, Saad Nseir, Mathilde Bouchereau, Sean Boyd, Luis Coelho, Julien Maizel, Pierre Cuchet, Wafa Zarrougui, Déborah Boyer, Jean-Pierre Quenot, Mehdi Imouloudene, Marc Pineton de Chambrun, Thierry Van der Linden, François Arrive, Sebastian Voicu, Elie Azoulay, Edgard Moglia, Frédéric Pene, Catia Cilloniz, Didier Thevenin, Charlotte Larrat, Laurent Argaud, Bertrand Guidet, Damien Contou, Alexandra Beurton, David Meguerditchian, Keyvan Razazi, Vassiliki Tsolaki, Mehdi Marzouk, Guillaume Brunin, Clémence Marois, Luis Morales
External validation of a prediction model for CPAP failure in COVID-19 patients with severe pneumonitis
Victoria Stokes, Kwee Yen Goh, Graham Whiting, Sebastian Bates, Hannah Greenlee, Anthony Wilson, Alexander J. Parker
Effective hemodynamic monitoring
Michael R. Pinsky, Maurizio Cecconi, Michelle S. Chew, Daniel De Backer, Ivor Douglas, Mark Edwards, Olfa Hamzaoui, Glenn Hernandez, Greg Martin, Xavier Monnet, Bernd Saugel, Thomas W. L. Scheeren, Jean-Louis Teboul, Jean-Louis Vincent
Early administration of hydrocortisone, vitamin C, and thiamine in adult patients with septic shock: a randomized controlled clinical trial
Qing-Quan Lyu, Rui-Qiang Zheng, Qi-Hong Chen, Jiang-Quan Yu, Jun Shao, Xiao-Hua Gu
Early identification of bleeding in trauma patients: external validation of traumatic bleeding scores in the Swiss Trauma Registry
Alan Costa, Pierre-Nicolas Carron, Tobias Zingg, Ian Roberts, François-Xavier Ageron
The prognostic value of early measures of the ventilatory ratio in the ARDS ROSE trial
Ana Carolina Costa Monteiro, Sitaram Vangala, Katherine D. Wick, Kevin L. Delucchi, Emily R. Siegel, B. Taylor Thompson, Kathleen D. Liu, Anil Sapru, Pratik Sinha, Michael A. Matthay
The best PEEP or the optimal PEEP or the piece PEEP of the mechanical power puzzle?
George Briassoulis, Panagiotis Briassoulis, Stavroula Ilia
Early intubation and patient-centered outcomes in septic shock
Jianmin Qu, Yanfei Shen, Huijuan Zhang
Oropharyngeal and intestinal concentrations of opportunistic pathogens are independently associated with death of SARS-CoV-2 critically ill adults
Juliette Patrier, Khanh Villageois-Tran, Piotr Szychowiak, Stéphane Ruckly, Rémi Gschwind, Paul-Henri Wicky, Signara Gueye, Laurence Armand-Lefevre, Mehdi Marzouk, Romain Sonneville, Lila Bouadma, Marie Petitjean, Fariza Lamara, Etienne de Montmollin, Jean-Francois Timsit, Etienne Ruppé, Laurent Abel, Amal Abrous, Claire Andrejak, François Angoulvant, Delphine Bachelet, Marie Bartoli, Sylvie Behilill, Marine Beluze, Krishna Bhavsar, Lila Bouadma, Minerva Cervantes-Gonzalez, Anissa Chair, Charlotte Charpentier, Léo Chenard, Catherine Chirouze, Sandrine Couffin-Cadiergues, Camille Couffignal, Marie-Pierre Debray, Dominique Deplanque, Diane Descamps, Alpha Diallo, Fernanda Dias da Silva, Céline Dorival, Xavier Duval, Philippine Eloy, Vincent Enouf, Hélène Esperou, Marina Esposito-Farese, Manuel Etienne, Aline-Marie Florence, Alexandre Gaymard, Jade Ghosn, Tristan Gigante, Morgane Gilg, François Goehringer, Jérémie Guedj, Ikram Houas, Isabelle Hoffmann, Jean-Sébastien Hulot, Salma Jaafoura, Ouifiya Kafif, Antoine Khalil, Nadhem Lafhej, Cédric Laouénan, Samira Laribi, Minh Le, Quentin Le Hingrat, Soizic Le Mestre, Sophie Letrou, Yves Levy, Bruno Lina, Guillaume Lingas, Denis Malvy, France Mentré, Hugo Mouquet, Nadège Neant, Christelle Paul, Aurélie Papadopoulos, Christelle Paul, Ventzislava Petrov-Sanchez, Gilles Peytavin, Valentine Piquard, Olivier Picone, Manuel Rosa-Calatrava, Bénédicte Rossignol, Patrick Rossignol, Carine Roy, Marion Schneider, Richa Su, Coralie Tardivon, Jean-François Timsit, Sarah Tubiana, Sylvie Van Der Werf, Benoit Visseaux, Aurélie Wiedemann
Impact of frailty on clinical outcomes in patients with and without COVID-19 pneumonitis admitted to intensive care units in Australia and New Zealand: a retrospective registry data analysis
Ashwin Subramaniam, Kiran Shekar, Christopher Anstey, Ravindranath Tiruvoipati, David Pilcher
Trends in mortality in septic patients according to the different organ failure during 15 years
Carolina Lorencio Cárdenas, Juan Carlos Yébenes, Emili Vela, Montserrat Clèries, Josep Mª Sirvent, Cristina Fuster-Bertolín, Clara Reina, Alejandro Rodríguez, Juan Carlos Ruiz-Rodríguez, Josep Trenado, Elisabeth Esteban Torné
Right ventricular outflow tract Doppler flow analysis and pulmonary arterial coupling by transthoracic echocardiography in sepsis: a retrospective exploratory study
Emma Maria Bowcock, Benjamin Gerhardy, Stephen Huang, Sam Orde
Evaluation of inhaled nitric oxide (iNO) treatment for moderate-to-severe ARDS in critically ill patients with COVID-19: a multicenter cohort study
Khalid Al Sulaiman, Ghazwa B. Korayem, Ali F. Altebainawi, Shmeylan Al Harbi, Abdulrahman Alissa, Abdullah Alharthi, Raed Kensara, Amjaad Alfahed, Ramesh Vishwakarma, Hussain Al Haji, Naif Almohaimid, Omar Al Zumai, Fahad Alrubayan, Abdulmajid Asiri, Nasser Alkahtani, Abdulaziz Alolayan, Samiah Alsohimi, Nawal Melibari, Alaa Almagthali, Seba Aljahdali, Abeer A. Alenazi, Alawi S. Alsaeedi, Ghassan Al Ghamdi, Omar Al Faris, Joud Alqahtani, Jalal Al Qahtani, Khalid A. Alshammari, Khalil I. Alshammari, Ohoud Aljuhani
Doppler study of portal vein and renal venous velocity predict the appropriate fluid response to diuretic in ICU: a prospective observational echocardiographic evaluation
Pierre-Grégoire Guinot, Pierre-Alain Bahr, Stefan Andrei, Bogdan A. Popescu, Vincenza Caruso, Paul-Michel Mertes, Vivien Berthoud, Maxime Nguyen, Belaid Bouhemad
Optimized diagnosis-based comorbidity measures for all-cause mortality prediction in a national population-based ICU population
Anna Aronsson Dannewitz, Bodil Svennblad, Karl Michaëlsson, Miklos Lipcsey, Rolf Gedeborg
Association between in-ICU red blood cells transfusion and 1-year mortality in ICU survivors
Alice Blet, Joel B. McNeil, Julie Josse, Bernard Cholley, Raphaël Cinotti, Gad Cotter, Agnès Dauvergne, Beth Davison, Kévin Duarte, Jacques Duranteau, Marie-Céline Fournier, Etienne Gayat, Samir Jaber, Sigismond Lasocki, Thomas Merkling, Katell Peoc’h, Imke Mayer, Malha Sadoune, Pierre-François Laterre, Romain Sonneville, Lorraine Ware, Alexandre Mebazaa, Antoine Kimmoun
Renaissance of glucocorticoids in critical care in the era of COVID-19: ten urging questions
Martin S. Winkler, Marcin F. Osuchowski, Didier Payen, Antoni Torres, Steffen Dickel, Tomasz Skirecki
PEEP, p-values, and pulmonary mechanics; don’t throw the baby out with the bathwater
Matthew E. Cove, Michael R. Pinsky, John J. Marini
Ten areas for ICU clinicians to be aware of to help retain nurses in the ICU
Jean-Louis Vincent, Carole Boulanger, Margo M. C. van Mol, Laura Hawryluck, Elie Azoulay
Microcirculatory alterations in critically ill COVID-19 patients analyzed using artificial intelligence
Matthias Peter Hilty, Emanuele Favaron, Pedro David Wendel Garcia, Yavuz Ahiska, Zuhre Uz, Sakir Akin, Moritz Flick, Sesmu Arbous, Daniel A. Hofmaenner, Bernd Saugel, Henrik Endeman, Reto Andreas Schuepbach, Can Ince
Delivery decision in pregnant women rescued by ECMO for severe ARDS: a retrospective multicenter cohort study
Sarah Aissi James, Christophe Guervilly, Mathieu Lesouhaitier, Alexandre Coppens, Clément Haddadi, Guillaume Lebreton, Jacky Nizard, Nicolas Brechot, Benjamin Assouline, Ouriel Saura, David Levy, Lucie Lefèvre, Pétra Barhoum, Juliette Chommeloux, Guillaume Hékimian, Charles-Edouard Luyt, Antoine Kimmoun, Alain Combes, Matthieu Schmidt
Early hyperoxia and 28-day mortality in patients on venoarterial ECMO support for refractory cardiogenic shock: discussion about potential confounding factors
Hadrien Winiszewski, Gael Piton, Gilles Capellier
Integrating electrical impedance tomography and transpulmonary pressure monitoring to personalize PEEP in hypoxemic patients undergoing pressure support ventilation
Douglas Slobod, Marco Leali, Elena Spinelli, Domenico Luca Grieco, Savino Spadaro, Tommaso Mauri
Algorithmic fairness audits in intensive care medicine: artificial intelligence for all?
Davy van de Sande, Jasper van Bommel, Eline Fung Fen Chung, Diederik Gommers, Michel E. van Genderen
Individualizing mechanical ventilation: titration of driving pressure to pulmonary elastance through Young’s modulus in an acute respiratory distress syndrome animal model
Álvaro Mingote, Ramsés Marrero García, Martín Santos González, Raquel Castejón, Clara Salas Antón, Juan Antonio Vargas Nuñez, Javier García-Fernández
Hospital change to mixed lipid emulsion from soybean oil-based lipid emulsion for parenteral nutrition in hospitalized and critically ill adults improves outcomes: a pre–post-comparative study
Krista L. Haines, Tetsu Ohnuma, Charles Trujillo, Obanor Osamudiamen, Vijay Krishnamoorthy, Karthik Raghunathan, Paul E. Wischmeyer
Early versus delayed enteral nutrition in mechanically ventilated patients with circulatory shock: statistics fallacy of logistic regression model
Shohei Ono
Different epidemiology of bloodstream infections in COVID-19 compared to non-COVID-19 critically ill patients: a descriptive analysis of the Eurobact II study
Niccolò Buetti, Alexis Tabah, Ambre Loiodice, Stéphane Ruckly, Abdullah Tarik Aslan, Giorgia Montrucchio, Andrea Cortegiani, Nese Saltoglu, Bircan Kayaaslan, Firdevs Aksoy, Akova Murat, Özlem Akdoğan, Kemal Tolga Saracoglu, Cem Erdogan, Marc Leone, Ricard Ferrer, José-Artur Paiva, Yoshiro Hayashi, Mahesh Ramanan, Andrew Conway Morris, François Barbier, Jean-François Timsit, Jeffrey Lipman, Edward Litton, Anna Maria Palermo, Timothy Yap, Ege Eroglu, Koji Hosokawa, Hideki Yoshida, Shigeki Fujitani, Farid Zand, Ata Mahmoodpoor, Seyed Mohammad Nasirodin Tabatabaei, Omar Elrabi, Ghaleb A. Almekhlafi, Gabriela Vidal, Marta Aparicio, Irene Alonzo, Silvio A. Namendys-Silva, Mariana Hermosillo, Roberto Alejandro Castillo, Liesbet De Bus, Jan De Waele, Isabelle Hollevoet, Nicolas De Schryver, Nicolas Serck, Pedja Kovacevic, Biljana Zlojutro, Etienne Ruppe, Philippe Montravers, Thierry Dulac, Jérémy Castanera, Alexandre Massri, Charlotte Guesdon, Pierre Garcon, Matthieu Duprey, François Philippart, Marc Tran, Cédric Bruel, Pierre Kalfon, Gaëtan Badre, Sophie Demeret, Loïc Le Guennec, Matteo Bassetti, Daniele Giacobbe, Gabriele Sales, Ivan Daroui, Giovanni Lodi, Mariachiara Ippolito, Davide Bellina, Andrea Di Guardo, Monica Rocco, Silvia Fiorelli, Adam Mikstacki, Mariusz Peichota, Iwona Pietraszek-Grzywaczewska, Pedro Póvoa, Andriy Krystopchuk, Ana Teresa, António Manuel Pereira de Figueiredo, Isabel Botelho, Vasco Costa, Rui Pedro Cunha, Alexey Gritsan, Vladislav Belskiy, Mikhail Furman, Maria Martinez, Vanessa Casares, Maria Pilar Gracia Arnillas, Rosana Munoz Bermudez, Alejandro Ubeda, Maria Salgado, Emilio Maseda, Alejandro Suarez De La Rica, Miguel Angel Blasco-Navalpotro, Alberto Orejas Gallego, Josef Prazak, J. L. Pagani, S. Abed-Maillard, Arzu Topeli Iskit, Selcuk Mehtap, Solakoğlu Ceyhun, Ayşe Kaya Kalem, Ibrahim Kurt, Murat Telli, Barcin Ozturk, Nurcan Baykam, Ridvan Karaali, Iftihar Koksal, Yeliz Bilir, Seda Guzeldag, Gulden Ersoz, Guliz Evik, Yasar Bayindir, Yasemin Ersoy, Ari Ercole, Ashok Raj, Artemis Zormpa, George Tinaslanidis, Reena Khade, Ashraf Roshdy, Santhana Kannan, Supriya Antrolikar, Nicholas Marsden, Ben Attwood, Jamie Patel, Mohan Gurjar, Carol Dsilva, Jagadish Chandran, Bashir El Sanousi, Elfayadh Saidahmed, Hytham K. S. Hamid
An area under the concentration–time curve threshold as a predictor of efficacy and nephrotoxicity for individualizing polymyxin B dosing in patients with carbapenem-resistant gram-negative bacteria
Jing Yang, Shaohua Liu, Jingli Lu, Tongwen Sun, Peile Wang, Xiaojian Zhang
Circulating N-formylmethionine and metabolic shift in critical illness: a multicohort metabolomics study
Martin Ingi Sigurdsson, Hirotada Kobayashi, Karin Amrein, Kiichi Nakahira, Angela J. Rogers, Mayra Pinilla-Vera, Rebecca M. Baron, Laura E. Fredenburgh, Jessica A. Lasky-Su, Kenneth B. Christopher
Dehydration is associated with production of organic osmolytes and predicts physical long-term symptoms after COVID-19: a multicenter cohort study
Michael Hultström, Miklos Lipcsey, Dave R. Morrison, Tomoko Nakanishi, Guillaume Butler-Laporte, Yiheng Chen, Satoshi Yoshiji, Vincenzo Forgetta, Yossi Farjoun, Ewa Wallin, Ing-Marie Larsson, Anders Larsson, Adriana Marton, Jens Marc Titze, Sandra Nihlén, J. Brent Richards, Robert Frithiof
Oxygen targets and 6-month outcome after out of hospital cardiac arrest: a pre-planned sub-analysis of the targeted hypothermia versus targeted normothermia after Out-of-Hospital Cardiac Arrest (TTM2) trial
Chiara Robba, Rafael Badenes, Denise Battaglini, Lorenzo Ball, Filippo Sanfilippo, Iole Brunetti, Janus Christian Jakobsen, Gisela Lilja, Hans Friberg, Pedro David Wendel-Garcia, Paul J. Young, Glenn Eastwood, Michelle S. Chew, Johan Unden, Matthew Thomas, Michael Joannidis, Alistair Nichol, Andreas Lundin, Jacob Hollenberg, Naomi Hammond, Manoj Saxena, Annborn Martin, Miroslav Solar, Fabio Silvio Taccone, Josef Dankiewicz, Niklas Nielsen, Anders Morten Grejs, Florian Ebner, Paolo Pelosi, Jan Bělohlávek, Clifton Callaway, Alain Cariou, Tobias Cronberg, David Erlinge, Jan Hovdenes, Hans Kirkegaard, Helena Levin, Matt P. G. Morgan, Per Nordberg, Mauro Oddo, Christian Rylander, Christian Storm, Susann Ullén, Matt P. Wise, Kathy Rowan, David Harrison, Paul Mouncey, Manu Shankar-Hari, Duncan Young, Theis Lange, Karolina Palmér, Ulla-Britt Karlsson, Simon Heissler, Frances Bass, John Myburgh, Colman Taylor, Adele Bellino, Marwa Abel-all, Ben Finfer, Carolyn Koch, Yang Li, Anne O’Connor, Julia Pilowsky, Tina Schneider, Anna Tippett, Bridget Ady, Tessa Broadley, Amanda Brown, Liz Melgaard, Mimi Morgan, Vanessa Singh, Rebecca Symons, Kathrin Becker, Nathalie Sante, Vendula Saleova, Silvie Zerzanova, Samia Sefir-Kribel, Ute Lübeck, Martina Carrara, Kathryn Fernando, Diane Mackle, Leanlove Navarra, Judith Riley, Elin Westerheim, Marianne Flatebø, Ameldina Ceric, Zana Haxhija, Lovisa Terling, Lena Bossmar, Liz Jergle, Helén Holm Månsson, Samia Abed Maillard, Andreja Vujicic Zagar, Christina Jodlauk, Jennifer Scrivens, Kate Ainscough, Ciara Fahey, Rinaldo Bellomo, Leah Peck, Helen Young, Winston Cheung, Rosalba Cross, Michael Hayes, Nitin Jain, Mark Kol, Asim Shah, Atul Wagh, Helen Wong, F. Eduardo Martinez, Gail Brinkerhoff, Dustin Bush, Antony Stewart, Anders Aneman, Lien Lombardo, Peter McCanny, James Penketh, Ian Seppelt, Rebecca Gresham, Julie Lowrey, Kristy Masters, Christina Whitehead, James Walsham, Meg Harward, Josephine Mackay, Jason Meyer, Emma Saylor, Ellen Venz, Krista Wetzig, Wade Stedman, Angela Ashelford, Sharon Mar, Miyuki Tokumitsu, Elizabeth Yarad, Hergen Buscher, Claire Reynolds, Andrew Udy, Aidan Burrell, Jasmin Collins, Dashiell Gantner, Victoria Emma-Leah Martin, Phoebe Mccracken, Vinodh Nanjayya, Alexander Sacha Richardson, Meredith Young, Angaj Ghosh, Simone Said, Ronny Beer, Frank Hartig, Raimund Helbok, Sebastian Klein, Andreas Peer, Jacques Creteur, Dominique Durand, Matthias Dupont, Sigrid Christiaens, Carola Claes, Sebastiaan Deckx, Bert Ferdinande, Sanne Lenaerts, Wilifred Mullens, Sarah Stroobants, Evi Theunissen, David Verhaert, Ondřej Šmíd, Marek Flaksa, David Kemlink, Jan Malík, Michal Otáhal, Jan Rulíšek, Michal Šíranec, Zdeněk Stach, Anna Valeriánová, Petra Zavadilova, Miroslav Solař, Róber Bánszky, Jana Červená, Renata Černá Pařízková, Libor Šimůnek, Filip Varhaník, Jiří Karásek, Matěj Strýček, Anders Grejs, Steffen Christensen, Peter Juhl-Olsen, Ida Katrine Thomsen, Lisa Gregersen Østergaard, Albert Cao, Pierre Dupland, Ariane Gavaud, Paul Jaubert, Mathieu Jozwiak, Nathalie Marin, Guillaume Savary, Nicolas Deye, Bruno Megarbane, Pierre Mora, Laetitia Sutterlin, Stephane Legriel, Hugo Bellut, Alexis Ferre, Guillaume Lacave, Marine Paul, Jean-Baptiste Lascarrou, Emmanuel Canet, Charlotte Garret, Arnaud Felix Miaihle, Jean Reignier, Philippe Vignon, Thomas Daix, Arnaud Desachy, Bruno Evrard, Bruno Francois, Anne-Laure Fedou, Marine Goudelin, Christoph Leithner, Jens Nee, Kaspar Josche Streitberger, Giulia Bonatti, Iacopo Firpo, Paolo Frisoni, Arianna Iachi, Simona Maiani, Maura Mandelli, Fabio Tarantino, Alberto Barbieri, Elisabetta Bertellini, Enrico Giuliani, Gabriele Melegari, Erik Roman-Pognuz, Giorgio Berlot, Umberto Lucangelo, Elisabetta Macchini, Vibeke Aune, Tomas Drægni, Simon Jacobsen, Søren Pieschke, Åse Rasmussen, Gro Ringstad Akselsen, Halvor Langeland, Daniel Bergum, Therese M Erbe, Pål Klepstad, Helle M Næss, Roy Bjørkholt Olsen, Lena Eriksen Skjelnes, Marius Holen, Joakim Iver Post, Rune Fanebust, Linda Hårteig Sørensen, Ken Åge Kårstad, CarstenFredrik Wickman, Colin Barnes, Ben Barry, Nina Beehre, Dick Dinsdale, Sam Edney, Anna Hunt, Harriet Judd, Charlotte Latimer-Bell, Cassie Lawrence, James Moore, Shaanti Olatunji, Alex Psirides, Chelsea Robinson, Kate Tietjens, Jason Wright, David Knight, Brandon Birker, David Bowie, Tara Burke, David Closey, Rosalind Crombie, Neil Davidson, Seton Henderson, Louise Hitchings, James McKay, Jan Mehrtens, Emmeline Minto, Stacey Morgan, Anna Morris, Jay Ritzemar-Carter, Jessica Roberts, Geoffrey Shaw, Katherine Townend, Kymbalee Vander Heyden, Marita Ahlqvist, Roman Desta Lindgren, Ingrid Eiving, Patrik Martner, Elisabeth Myhrman, Birgitta Ryding, Joachim Düring, Mattias Bergström, Mattias Bohm, Ingrid Didriksson, Petrea Frid, Katarina Heimburg, Marina Larsson, Oscar Lundberg, Stefan Olsson Hau, Simon Schmidbauer, Ola Borgquist, Anne Adolfsson, Anna Bjärnroos, Erik Blennow-Nordström, Irina Dragancea, Thomas Kander, Anna Lybeck, Gustav Mattiasson, Olof Persson, Malin Rundgren, Susann Schrey, Erik Westhall, Martin Annborn, Sara Andertun, Nerida Gustavsson, Lisa Hassel, Jesper Johnsson, Marie Nelderup, Heléne Petersson, Jörgen Petersson, Frideriki Stafilidou, Johan Undén, Frida Antonsson, Git Bergman, Jörgen Gamroth, Maria Meirik, Katarina Rudolfsson, Helena Sandberg, Martin Thorsson, Kristin Savolainen, Maria Hansbo, Malin Helliksson, Björne Nödtveidt, Johan Sanner, Victoria Sem, Camilla Sund Lindquist, Akil Awad, Anna-Sofia Börjesson, Malin Hedberg, Mia Henning, Per Petersen, Emelia Dahlberg, Johan Forshammar, Veronica Svensson, Michael Wanecek, Håkan Eskilsson, Daniel Rodriguez-Santos, Åsa Appelqvist, Henrietta Jidbratt, Elisabeth Johansson, Lars Kiszakiewicz, Åsa Nilsson, Sinnika Olsson, Anders Paulsson, Urszula Stempel, Andreas Thoren, Stefan Persson, Ida Berglund, Eric Bergström, Cathrine Törnqvist, Ingela Östman, Sten Rubertsson, Ing-Marie Larsson, Elin Söderman, Ewa Wallin, Joanna Wessbergh, Thomas Halliday, Filippa Engvall, Nawfel Ben-Hamouda, Adriano Bernini, Pierre-Nicolas Carron, Philippe Eckert, Eva Favre, John-Paul Miroz, Paola Morelli, Olivier Muller, Jan Novi, Andrea Rosseti, Madeleine Schnorf, Matthias Haenggi, Anja Levis, Sandra Nansoz, Marianne Roth & Team, Nicole Söll, Claudia Schrag, Mensur Alicajic, Philipp Baier, Joel Dütschler, Dominique Flügel, Edith Fässler, Ruth Gamio-Veis, Marc Güpfert, Yvonne Hilpertshauser, Stefan Hägele-Link, Gian-Reto Kleger, Peter Krähenmann, Maria Elisabeth Mair, Nadja Schai, Christoph Strohmaier, Peter Tangl, Dominik Zieglgänsberger, Marco Maggiorini, Gabriele Claus, Gabi Consani-Vogel, Lukas Imbach, Samira Kaiser, Eva-Maria Kleinert, Pedro David Wendel Garcia, Tiziano Cassina, Pamela Agazzi, Bruno Capelli, Gabriele Casso, Martino Regazzi, Hervé Schlotterbeck, Gabriele Via, Michele Villa, Jenny Brooks, Eve Cocks, Jade Cole, Jacqueline Curtin, Michelle Davies, Rhys Davies, Stephen Fernandez, Julie Highfield, Helen Hill, Lydia Pennant, Sofia Rose, Emma Thomas, Angharad Williams, Peter McGuigan, Stephen Haffey, Aisling O’Neill, Kathryn Ward, Jeremy Bewley, Anna Chillingworth, Julie Cloake, Libby Cole, Hilary Galvin, Zoe Garland, Lisa Grimmer, Bethany Gumbrill, Lucy Howie, Rebekah Johnson, Chloe Searles, Agnieszka Skorko, Katie Sweet, Victoria Taylor, Denise Webster, Thomas Keeble, Gill Adams, Rajesh K. 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Comparison of continuous versus intermittent enteral feeding in critically ill patients: a systematic review and meta-analysis
Aaron J. Heffernan, C. Talekar, M. Henain, L. Purcell, M. Palmer, H. White
Virtual and augmented reality in critical care medicine: the patient’s, clinician’s, and researcher’s perspective
Raphael Romano Bruno, Georg Wolff, Bernhard Wernly, Maryna Masyuk, Kerstin Piayda, Susannah Leaver, Ralf Erkens, Daniel Oehler, Shazia Afzal, Houtan Heidari, Malte Kelm, Christian Jung
Higher PEEP in intubated COVID-19-associated ARDS patients? We are not sure
Andrey I. Yaroshetskiy, Sergey N. Avdeev, Anna P. Krasnoshchekova, Galia S. Nuralieva
Chest dual-energy CT to assess the effects of steroids on lung function in severe COVID-19 patients
Gaetano Perchiazzi, Aleksandra Larina, Tomas Hansen, Robert Frithiof, Michael Hultström, Miklos Lipcsey, Mariangela Pellegrini
Wearable ultrasound and provocative hemodynamics: a view of the future
Jon-Émile S. Kenny, Chelsea E. Munding, Andrew M. Eibl, Joseph K. Eibl
Extracorporeal versus conventional cardiopulmonary resuscitation for refractory out-of-hospital cardiac arrest: a secondary analysis of the Prague OHCA trial
Daniel Rob, Jana Smalcova, Ondrej Smid, Ales Kral, Tomas Kovarnik, David Zemanek, Petra Kavalkova, Michal Huptych, Arnost Komarek, Ondrej Franek, Stepan Havranek, Ales Linhart, Jan Belohlavek
Hyperoxia in patients on venoarterial extracorporeal membrane oxygenation
Chenglong Li, Xiaomeng Wang, Xiaotong Hou
Future without delirium: not quite there yet but we can start by prescribing touch
Susana M. Fernandes, Maria Adão-Serrano, Ana Rita Rodrigues, Patrícia Belo
Proenkephalin A 119–159 predicts early and successful liberation from renal replacement therapy in critically ill patients with acute kidney injury: a post hoc analysis of the ELAIN trial
Thilo von Groote, Felix Albert, Melanie Meersch, Raphael Koch, Christian Porschen, Oliver Hartmann, Deborah Bergmann, Peter Pickkers, Alexander Zarbock
Negative pressure ventilation protects the brain
C. M. van Rijn, J. van Egmond, D. Howard, M. G. Coulthard, P. Perella, J. H. M. Roberts, D. McKeown
Public-access defibrillation and favorable neurological outcome after out-of-hospital cardiac arrest during the COVID-19 pandemic in Japan
Tasuku Matsuyama, Kosuke Kiyohara, Tetsuhisa Kitamura, Chika Nishiyama, Takeyuki Kiguchi, Taku Iwami
How symptoms of prolonged grief disorder, posttraumatic stress disorder, and depression relate to each other for grieving ICU families during the first two years of bereavement
Fur-Hsing Wen, Holly G. Prigerson, Wen-Chi Chou, Chung-Chi Huang, Tsung-Hui Hu, Ming Chu Chiang, Li-Pang Chuang, Siew Tzuh Tang
Public awareness and knowledge of sepsis: a cross-sectional survey of adults in Canada
Jeanna Parsons Leigh, Rebecca Brundin-Mather, Stephana Julia Moss, Angie Nickel, Ariana Parolini, Deirdre Walsh, Blair L. Bigham, Alix J. E. Carter, Alison Fox-Robichaud, Kirsten M. Fiest
Use of an innovative cuff pressure control and subglottic secretions drainage system in COVID-19 ARDS patients undergoing pronation
Eloisa Sofia Tanzarella, Gianmarco Lombardi, Silvia Baroni, Francesca Sarlo, Salvatore Lucio Cutuli, Simone Carelli, Melania Cesarano, Veronica Gennenzi, Gabriele Pintaudi, Joel Vargas, Antonio Maria Dell’Anna, Domenico Luca Grieco, Andrea Urbani, Massimo Antonelli, Gennaro De Pascale
Electrical impedance tomography for titration of positive end-expiratory pressure in acute respiratory distress syndrome patients with chronic obstructive pulmonary disease
Xuesong Liu, Xiao Liu, Jue Meng, Dongdong Liu, Yongbo Huang, Ling Sang, Yonghao Xu, Zhiheng Xu, Weiqun He, Sibei Chen, Rong Zhang, Xiaoqing Liu, Yimin Li
Longitudinal phenotypes in patients with acute respiratory distress syndrome: a multi-database study
Hui Chen, Qian Yu, Jianfeng Xie, Songqiao Liu, Chun Pan, Ling Liu, Yingzi Huang, Fengmei Guo, Haibo Qiu, Yi Yang
A genome-wide association study of survival in patients with sepsis
Tamara Hernandez-Beeftink, Beatriz Guillen-Guio, Jose M. Lorenzo-Salazar, Almudena Corrales, Eva Suarez-Pajes, Rui Feng, Luis A. Rubio-Rodríguez, Megan L. Paynton, Raquel Cruz, M. Isabel García-Laorden, Miryam Prieto-González, Aurelio Rodríguez-Pérez, Demetrio Carriedo, Jesús Blanco, Alfonso Ambrós, Elena González-Higueras, Elena Espinosa, Arturo Muriel, Eduardo Tamayo, María M. Martin, Leonardo Lorente, David Domínguez, Abelardo García de Lorenzo, Heather M. Giannini, John P. Reilly, Tiffanie K. Jones, José M. Añón, Marina Soro, Ángel Carracedo, Louise V. Wain, Nuala J. Meyer, Jesús Villar, Carlos Flores
PSP is a promising biomarker of sepsis; however, potential elimination by RRT must be considered
Patrick M. Honore, Sebastien Redant, Pharan Djimafo, Sydney Blackman, Ibrahim Bousbiat, Emily Perriens, Thierry Preseau, Bogdan Vasile Cismas, Keitiane Kaefer, Leonel Barreto Gutierrez, Sami Anane, Andrea Gallerani, Rachid Attou
Corticotropin-stimulated steroid profiles to predict shock development and mortality in sepsis: From the HYPRESS study
Josef Briegel, Patrick Möhnle, Didier Keh, Johanna M. Lindner, Anna C. Vetter, Holger Bogatsch, Dorothea Lange, Sandra Frank, Ludwig C. Hinske, Djillali Annane, Michael Vogeser, Michael Bauer, Thorsten Brenner, Patrick Meybohm, Markus Weigand, Matthias Gründling, Markus Löffler, Michael Kiehntopf, Frank Bloos, Gunnar Elke, Melanie Meersch-Dini, Christian Putensen, Achim Kaasch, Stefan Kluge
A universal predictive and mechanistic urinary peptide signature in acute kidney injury
Alexis Piedrafita, Justyna Siwy, Julie Klein, Amal Akkari, Ana Amaya-garrido, Alexandre Mebazaa, Anna Belen Sanz, Benjamin Breuil, Laura Montero Herrero, Bertrand Marcheix, François Depret, Lucie Fernandez, Elsa Tardif, Vincent Minville, Melinda Alves, Jochen Metzger, Etienne Grunenwald, Guylène Feuillet, Marie Buléon, Manon Brunet, Nicolas Mayeur, Audrey Casemayou, François Labaste, Julia Grossac, Harald Mischak, Alberto Ortiz, Stéphane Gazut, Joost P. Schanstra, Stanislas Faguer
Hyperoxia during venoarterial ECMO: Culprit or co-variate? A comment from the BLENDER investigators
Lavienraj Premraj, Alastair Brown, Aidan Burrell, John F. Fraser, David Pilcher
The ICU Bridge Program: volunteers bridging medicine and people together
Sarah Petrecca, Adrian Goin, David Hornstein, Milanka Stevanovic, Adamo Anthony Donovan
Daily fluctuations in kidney function in critically ill adults
Chao-Yuan Huang, Fabian Güiza, Greet De Vlieger, Geert Meyfroidt
High-flow nasal cannula versus non-invasive ventilation for acute hypercapnic respiratory failure in adults: a systematic review and meta-analysis of randomized trials
N. Ovtcharenko, E. Ho, W. Alhazzani, A. Cortegiani, B. Ergan, R. Scala, G. Sotgiu, D. Chaudhuri, S. Oczkowski, K. Lewis
Comparative accuracy of biomarkers for the prediction of hospital-acquired acute kidney injury: a systematic review and meta-analysis
Heng-Chih Pan, Shao-Yu Yang, Terry Ting-Yu Chiou, Chih-Chung Shiao, Che-Hsiung Wu, Chun-Te Huang, Tsai-Jung Wang, Jui-Yi Chen, Hung-Wei Liao, Sheng-Yin Chen, Tao-Min Huang, Ya-Fei Yang, Hugo You-Hsien Lin, Ming-Jen Chan, Chiao-Yin Sun, Yih-Ting Chen, Yung-Chang Chen, Vin-Cent Wu
Spontaneous pneumomediastinum: a surrogate of P-SILI in critically ill COVID-19 patients
Alexandre Elabbadi, Tomas Urbina, Enora Berti, Damien Contou, Gaëtan Plantefève, Quintana Soulier, Audrey Milon, Guillaume Carteaux, Guillaume Voiriot, Muriel Fartoukh, Aude Gibelin
What metabolites are removed by CRRT except creatinine?
Yue Li, Wenhua Liu, Kaijiang Yu, Hongliang Wang, Changsong Wang
Fluid intake, fluid output or fluid balance, which one matters in ARDS
Yanfei Shen, Guolong Cai, Jing Yan
Real-time monitoring of air pathogens in the ICU with biosensors and robots
Linghua Yu
Trends in survival during the pandemic in patients with critical COVID-19 receiving mechanical ventilation with or without ECMO: analysis of the Japanese national registry data
Shinichiro Ohshimo, Keibun Liu, Takayuki Ogura, Yoshiaki Iwashita, Shigeki Kushimoto, Nobuaki Shime, Satoru Hashimoto, Yuji Fujino, Shinhiro Takeda
Safety, efficacy, and pharmacokinetics of gremubamab (MEDI3902), an anti-Pseudomonas aeruginosa bispecific human monoclonal antibody, in P. aeruginosa-colonised, mechanically ventilated intensive care unit patients: a randomised controlled trial
Jean Chastre, Bruno François, Marc Bourgeois, Apostolos Komnos, Ricard Ferrer, Galia Rahav, Nicolas De Schryver, Alain Lepape, Iftihar Koksal, Charles-Edouard Luyt, Miguel Sánchez-García, Antoni Torres, Philippe Eggimann, Despoina Koulenti, Thomas L. Holland, Omar Ali, Kathryn Shoemaker, Pin Ren, Julien Sauser, Alexey Ruzin, David E. Tabor, Ahmad Akhgar, Yuling Wu, Yu Jiang, Antonio DiGiandomenico, Susan Colbert, Drieke Vandamme, Frank Coenjaerts, Surbhi Malhotra-Kumar, Leen Timbermont, Antonio Oliver, Olivier Barraud, Terramika Bellamy, Marc Bonten, Herman Goossens, Colin Reisner, Mark T. Esser, Hasan S. Jafri, Michael Joannidis, Walter Klimscha, Elisabeth De Waele, Jacques Devriendt, Vincent Huberlant, Pieter Depuydt, Sam Van Boxstael, Mladen Peric, Jasminka Kopic, Michal Hanauer, Tomas Hruby, Vladimir Sramek, Petr Svoboda, Tomas Vymazal, Martin Novacek, Djillali Annane, Jean-Paul Mira, Bertrand Souweine, Pierre-François Dequin, Ferhat Meziani, François Stephan, Saadalla Nseir, Sebastien Gibot, Carole Schwebel, Gaetan Plantefeve, Jean-Luc Diehl, Christian Richard, Christian Lamer, Kada Klouche, Samir Jaber, Epaminondas Zakynthinos, Georgios Filntisis, Spyros Zakynthinos, Antonia Koutsoukou, Georgios Saroglou, Charikleia Nikolaou, Glykeria Vlachogianni, Ioannis Pnevmatikos, Konstantinos Mandragos, Ildiko Kremer, Zsolt Dezso Rozgonyi, Zsuzsa Marjanek, Ignacio Martin-Loeches, Pierre Singer, Vernon Van Heerden, Yehuda Carmeli, Pedro Povoa, Antonio Alvarez Seoane, Pedro Moura, Filipe Gonzalez, Paula Ramirez, Antonio Torres Marti, Ricard Ferrer Roca, Lorena Oteiza, Dolores Escudero, Enrique Piacentini, Paula Vera, Luis Tamayo, Miguel Angel Gonzalez Gallego, Borja Suberviola Canas, Iglesias Figueira, Rafael Leon, Volkan Korten, Murat Akova, Duncan Wyncoll, Tony Whitehouse, Phil Hopkins, Malcolm Sim, Yoav Golan, Marcus Zervos, Jose Vazquez, Kartikeya Cherabuddi, George Smulian, Nadine Rouphael, James Welker, Mathew Sims, David Van Duin, Todd McCarthy, Christopher Polk
Speed of cooling after cardiac arrest in relation to the intervention effect: a sub-study from the TTM2-trial
Rupert F. G. Simpson, Josef Dankiewicz, Grigoris V. Karamasis, Paolo Pelosi, Matthias Haenggi, Paul J. Young, Janus Christian Jakobsen, Jonathan Bannard-Smith, Pedro D. Wendel-Garcia, Fabio Silvio Taccone, Per Nordberg, Matt P. Wise, Anders M. Grejs, Gisela Lilja, Roy Bjørkholt Olsen, Alain Cariou, Jean Baptiste Lascarrou, Manoj Saxena, Jan Hovdenes, Matthew Thomas, Hans Friberg, John R. Davies, Niklas Nielsen, Thomas R. Keeble
Two regional ventilation–perfusion patterns of lung consolidation assessed by electrical impedance tomography and ultrasound
Na Wang, Huaiwu He, Yun Long, Dawei Liu, Qianling Wang, Jing Jiang, Yuechuan Xue, Siyi Yuan, Yi Chi, Zhanqi Zhao
Effect of an enteral amino acid blend on muscle and gut functionality in critically ill patients: a proof-of-concept randomized controlled trial
Nicholas Heming, Robert Carlier, Helene Prigent, Ahmed Mekki, Camille Jousset, Frederic Lofaso, Xavier Ambrosi, Rania Bounab, Virginie Maxime, Arnaud Mansart, Pascal Crenn, Pierre Moine, Fabien Foltzer, Bernard Cuenoud, Tobias Konz, John Corthesy, Maurice Beaumont, Mickaël Hartweg, Claudia Roessle, Jean-Charles Preiser, Denis Breuillé, Djillali Annane
Stress response during early sedation with dexmedetomidine compared with usual-care in ventilated critically ill patients
John P. R. Moore, Yahya Shehabi, Michael C. Reade, Michael Bailey, John F. Fraser, Lauren Murray, Christopher Anstey, Mervyn Singer
Fluid balance and renal replacement therapy initiation strategy: a secondary analysis of the STARRT-AKI trial
Ron Wald, Brian Kirkham, Bruno R. daCosta, Ehsan Ghamarian, Neill K. J. Adhikari, William Beaubien-Souligny, Rinaldo Bellomo, Martin P. Gallagher, Stuart Goldstein, Eric A. J. Hoste, Kathleen D. Liu, Javier A. Neyra, Marlies Ostermann, Paul M. Palevsky, Antoine Schneider, Suvi T. Vaara, Sean M. Bagshaw
Temperature control after cardiac arrest
Claudio Sandroni, Daniele Natalini, Jerry P. Nolan
Mobilisation of critically ill patients receiving norepinephrine: a retrospective cohort study
Maximilian Lindholz, Clara M. Schellenberg, Julius J. Grunow, Simone Kagerbauer, Annette Milnik, Daniel Zickler, Stefan Angermair, Anett Reißhauer, Martin Witzenrath, Mario Menk, Sebastian Boie, Felix Balzer, Stefan J. Schaller
Latent class analysis of imaging and clinical respiratory parameters from patients with COVID-19-related ARDS identifies recruitment subphenotypes
Daan F. L. Filippini, Elisa Di Gennaro, Rombout B. E. van Amstel, Ludo F. M. Beenen, Salvatore Grasso, Luigi Pisani, Lieuwe D. J. Bos, Marry R. Smit
Higher blood pressure versus normotension targets to prevent acute kidney injury: a systematic review and meta-regression of randomized controlled trials
Phu Nguyen Trong Tran, Prit Kusirisin, Piyanut Kaewdoungtien, Jeerath Phannajit, Nattachai Srisawat
Timing of dialysis in acute kidney injury using routinely collected data and dynamic treatment regimes
Paweł Morzywołek, Johan Steen, Stijn Vansteelandt, Johan Decruyenaere, Sigrid Sterckx, Wim Van Biesen
Systematized and efficient: organization of critical care in the future
Annette M. Esper, Yaseen M. Arabi, Maurizio Cecconi, Bin Du, Evangelos J. Giamarellos-Bourboulis, Nicole Juffermans, Flavia Machado, Sandra Peake, Jason Phua, Kathryn Rowan, Gee Young Suh, Greg S. Martin
Predictive factors for severe long-term chronic kidney disease after acute kidney injury requiring renal replacement therapy in critically ill patients: an ancillary study of the ELVIS randomized controlled trial
Edouard Soum, Jean-François Timsit, Stephane Ruckly, Didier Gruson, Emmanuel Canet, Kada Klouche, Laurent Argaud, Maïté Garrouste-Orgeas, Christophe Mariat, François Vincent, Sophie Cayot, Michael Darmon, Julien Bohé, Carole Schwebel, Lila Bouadma, Claire Dupuis, Bertrand Souweine, Alexandre Lautrette
Efficacy of noninvasive ventilation in patients with COVID-19
Yanfei Shen, Juqin Shao
Serum biomarkers identify critically ill traumatic brain injury patients for MRI
Sophie Richter, Stefan Winzeck, Endre Czeiter, Krisztina Amrein, Evgenios N. Kornaropoulos, Jan Verheyden, Gabriela Sugar, Zhihui Yang, Kevin Wang, Andrew I. R. Maas, Ewout Steyerberg, András Büki, Virginia F. J. Newcombe, David K. Menon, Krisztina Amrein, Nada Andelic, Lasse Andreassen, Audny Anke, Philippe Azouvi, Bo‑Michael Bellander, Habib Benali, Andras Buki, Alessio Caccioppola, Emiliana Calappi, Marco Carbonara, Giuseppe Citerio, Hans Clusmann, Mark Coburn, Jonathan Coles, Marta Correia, Endre Czeiter, Véronique De Keyser, Vincent Degos, Bart Depreitere, Live Eikenes, Erzsébet Ezer, Kelly Foks, Shirin Frisvold, Damien Galanaud, Alexandre Ghuysen, Ben Glocker, Asta Haberg, Iain Haitsma, Eirik Helseth, Peter J. Hutchinson, Evgenios Kornaropoulos, Noémi Kovács, Ana Kowark, Steven Laureys, Didier Ledoux, Hester Lingsma, Andrew I. R. Maas, Geoffrey Manley, David K. Menon, Tomas Menovsky, Benoit Misset, Visakh Muraleedharan, Ingeborg Nakken, Virginia Newcombe, Wibeke Nordhøy, József Nyirádi, Fabrizio Ortolano, Paul M. Parizel, Vincent Perlbarg, Paolo Persona, Wilco Peul, Jussi P. Posti, Louis Puybasset, Sophie Richter, Cecilie Roe, Olav Roise, Rolf Rossaint, Sandra Rossi, Daniel Rueckert, Toril Skandsen, Abayomi Sorinola, Emmanuel Stamatakis, Ewout W. Steyerberg, Nino Stocchetti, Riikka Takala, Viktória Tamás, Olli Tenovuo, Zoltán Vámos, Gregory Van der Steen, Wim Van Hecke, Thijs Vande Vyvere, Jan Verheyden, Anne Vik, Victor Volovici, Lars T. Westlye, Guy Williams, Stefan Winzeck, Peter Ylén, Tommaso Zoerle
Optimal PEEP with lowest (least injurious) transpulmonary driving pressure can be determined by a rapid two-PEEP-step procedure without esophageal pressure
O. Stenqvist
One-year hospital readmission for recurrent sepsis: associated risk factors and impact on 1-year mortality—a French nationwide study
Fanny Pandolfi, Christian Brun-Buisson, Didier Guillemot, Laurence Watier
A plea for personalization of the hemodynamic management of septic shock
Daniel De Backer, Maurizio Cecconi, Michelle S. Chew, Ludhmila Hajjar, Xavier Monnet, Gustavo A. Ospina-Tascón, Marlies Ostermann, Michael R. Pinsky, Jean-Louis Vincent
Outcomes in participants with failure of initial antibacterial therapy for hospital-acquired/ventilator-associated bacterial pneumonia prior to enrollment in the randomized, controlled phase 3 ASPECT-NP trial of ceftolozane/tazobactam versus meropenem
Marin H. Kollef, Jean-François Timsit, Ignacio Martin-Loeches, Richard G. Wunderink, Jennifer A. Huntington, Erin H. Jensen, Brian Yu, Christopher J. Bruno
Association between RBC transfusion and 1-year mortality in ICU survivors
M. M. Shangzhong Chen, M. M. Huojun Jiang, M. M. Caibao Hu
Parameters associated with successful weaning of veno-arterial extracorporeal membrane oxygenation: a systematic review
Francis Charbonneau, Karina Chahinian, Emmanuel Bebawi, Olivier Lavigueur, Émilie Lévesque, Yoan Lamarche, Karim Serri, Martin Albert, Pierre-Emmanuel Noly, Alexis Cournoyer, Yiorgos Alexandros Cavayas
Association between cholinesterase activity and critical illness brain dysfunction
Christopher G. Hughes, Christina S. Boncyk, Benjamin Fedeles, Pratik P. Pandharipande, Wencong Chen, Mayur B. Patel, Nathan E. Brummel, James C. Jackson, Rameela Raman, E. Wesley Ely, Timothy D. Girard
Augmented-Medication CardioPulmonary Resuscitation Trials in out-of-hospital cardiac arrest: a pilot randomized controlled trial
June-sung Kim, Seung Mok Ryoo, Youn-Jung Kim, Chang Hwan Sohn, Shin Ahn, Dong Woo Seo, Seok In Hong, Sang-Min Kim, Bora Chae, Won Young Kim
The central role of the gut in intensive care
Alberto Corriero, Raffaella Maria Gadaleta, Filomena Puntillo, Francesco Inchingolo, Antonio Moschetta, Nicola Brienza
The impact of different targeted temperatures on out-of-hospital cardiac arrest outcomes in patients receiving extracorporeal membrane oxygenation: a nationwide cohort study
Makoto Watanabe, Tasuku Matsuyama, Yuki Miyamoto, Tetsuhisa Kitamura, Sho Komukai, Bon Ohta
Personalised PEEP that yields the highest lung compliance versus optimal balance between overdistension and collapse during PSV: authors’ reply to Dr Stenqvist
Elena Spinelli, Douglas Slobod, Tommaso Mauri
Predicting neurological outcome in adult patients with cardiac arrest: systematic review and meta-analysis of prediction model performance
Simon A. Amacher, René Blatter, Matthias Briel, Christian Appenzeller-Herzog, Chantal Bohren, Christoph Becker, Katharina Beck, Sebastian Gross, Kai Tisljar, Raoul Sutter, Stephan Marsch, Sabina Hunziker
Ultra-lung-protective ventilation and biotrauma in severe ARDS patients on veno-venous extracorporeal membrane oxygenation: a randomized controlled study
Christophe Guervilly, Théotime Fournier, Juliette Chommeloux, Laurent Arnaud, Camille Pinglis, Karine Baumstarck, Mohamed Boucekine, Sabine Valera, Celine Sanz, Mélanie Adda, Mickaël Bobot, Florence Daviet, Ines Gragueb-Chatti, Jean-Marie Forel, Antoine Roch, Sami Hraiech, Françoise Dignat-George, Matthieu Schmidt, Romaric Lacroix, Laurent Papazian
Impact of COVID-19 pandemic on antifungal consumption: a multicenter retrospective analysis
Anne-Lise Bienvenu, Audrey Bestion, Pierre Pradat, Jean-Christophe Richard, Laurent Argaud, Céline Guichon, Sandrine Roux, Vincent Piriou, Carole Paillet, Gilles Leboucher, Florence Ader, Frédéric Aubrun, Charlotte Besson, Valentine Bréant, Charlotte Doudet, Sophie Ducastelle-Leprêtre, Damien Dupont, Marie-Delphine Guillemin, Véronique Leray, Charline Miossec, Sylvie Paulus, Anne-Marie Rabain, Pauline Rascle, Thomas Schulz, Michel Tod, Florent Valour, Florent Wallet, Martine Wallon
Association between age and the host response in critically ill patients with sepsis
Erik H. A. Michels, Joe M. Butler, Tom D. Y. Reijnders, Olaf L. Cremer, Brendon P. Scicluna, Fabrice Uhel, Hessel Peters-Sengers, Marcus J. Schultz, Julian C. Knight, Lonneke A. van Vught, Tom van der Poll, Friso M. de Beer, Lieuwe D. J. Bos, Gerie J. Glas, Arie J. Hoogendijk, Roosmarijn T. M. van Hooijdonk, Janneke Horn, Mischa A. Huson, Laura R. A. Schouten, Marleen Straat, Luuk Wieske, Maryse A. Wiewel, Esther Witteveen, Marc J. M. Bonten, Olaf M. Cremer, David S. Y. Ong, Jos F. Frencken, Peter M. C. Klein Klouwenberg, Maria E. Koster‐Brouwer, Kirsten van de Groep, Diana M. Verboom
Machine learning for the real-time assessment of left ventricular ejection fraction in critically ill patients: a bedside evaluation by novices and experts in echocardiography
Rita Varudo, Filipe A. Gonzalez, João Leote, Cristina Martins, Jacobo Bacariza, Antero Fernandes, Frederic Michard
Commentary: ‘Critical illness subclasses: all roads lead to Rome’
Mihir R. Atreya, L. Nelson Sanchez-Pinto, Rishikesan Kamaleswaran
Reply to: Higher PEEP in intubated COVID-19-associated ARDS patients? We are not sure
Peter Somhorst, Philip van der Zee, Henrik Endeman, Diederik Gommers
Continuous bladder urinary oxygen tension as a new tool to monitor medullary oxygenation in the critically ill
Raymond T. Hu, Yugeesh R. Lankadeva, Fumitake Yanase, Eduardo A. Osawa, Roger G. Evans, Rinaldo Bellomo
Ten rules for optimizing ventilatory settings and targets in post-cardiac arrest patients
Denise Battaglini, Paolo Pelosi, Chiara Robba
The pathogenesis and therapeutic strategies of heat stroke-induced liver injury
Fuquan Wang, Yan Zhang, Jianhua Li, Haifa Xia, Dingyu Zhang, Shanglong Yao
A prospective observational study on impact of epinephrine administration route on acute myocardial infarction patients with cardiac arrest in the catheterization laboratory (iCPR study)
Ali Aldujeli, Ayman Haq, Kristen M. Tecson, Zemyna Kurnickaite, Karolis Lickunas, Som Bailey, Vacis Tatarunas, Rima Braukyliene, Giedre Baksyte, Montazar Aldujeili, Hussein Khalifeh, Kasparas Briedis, Rasa Ordiene, Ramunas Unikas, Anas Hamadeh, Emmanouil S. Brilakis
Score-based prediction model for severe vitamin D deficiency in patients with critical illness: development and validation
Yu-Ting Kuo, Li-Kuo Kuo, Chung-Wei Chen, Kuo-Ching Yuan, Chun-Hsien Fu, Ching-Tang Chiu, Yu-Chang Yeh, Jen-Hao Liu, Ming-Chieh Shih
Perspective: the top 11 priorities to improve trauma outcomes, from system to patient level
Michael C. Reade
Mechanical ventilation variables associated with high pulmonary artery pressures in ARDS patients: a post hoc analysis
Joseph R. Riddell, Benjamin J. Jones, Bruno M. Fernandes, Daniel J. Law, Jackie A. Cooper, Matt P. Wise
Statistics on steroids: How recognizing competing risks gets us closer to the truth about COVID-19-associated VAP
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