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01.06.2023 | Original articles

Atrial fibrillation increases the risk of new-onset myocardial infarction amongst working-age population: a propensity-matched study

verfasst von: Bocheng Yue, Qiqi Hou, Julian Bredehorst, Quanle Han, MD, Boheng Zhang, Chao Zhang, Jiawei Zhang, Shuohua Chen, Shouling Wu, MD, Kangbo Li, MD PhD

Erschienen in: Herz | Ausgabe 5/2023

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Abstract

Objective

The aim of this study was to investigate the association between atrial fibrillation (AF) and new-onset myocardial infarction (MI) among a working-age population in an industrial city of North China.

Methods

In total 77,670 participants aged under 60 years were selected for this cohort study. Participants were divided into an AF group (n = 121) and a non-AF group (n = 74,565) based on their medical histories. Thereafter, 121 participants from the AF group were propensity-matched with 363 participants from the non-AF group. All participants were followed up from June 2006 to December 2020; new-onset MI was regarded as the endpoint of this study. Multivariate Cox proportional hazards regression analysis models were designed to analyze the correlation between AF and new-onset MI.

Results

During the 14-year follow-up, eight cases of new-onset MI were documented in the AF group, while five cases were documented in the non-AF group. The cumulative incidence of new-onset MI in the AF group (7.40%) was markedly higher than in the non-AF group (1.41%; p < 0.001). Atrial fibrillation was associated with an increased risk of new-onset MI in both univariate analysis (hazard ratio: 5.202, 95% confidence interval [CI]: 1.700–15.913) and multivariable-adjusted analysis (hazard ratio: 5.335, 95% CI: 1.683–16.910).

Conclusion

Atrial fibrillation increased the risk of new-onset MI amongst working-age individuals in an industrial city of North China.

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Titel: Atrial fibrillation increases the risk of new-onset myocardial infarction amongst working-age population: a propensity-matched study
verfasst von: Bocheng Yue
Qiqi Hou
Julian Bredehorst
Quanle Han, MD
Boheng Zhang
Chao Zhang
Jiawei Zhang
Shuohua Chen
Shouling Wu, MD
Kangbo Li, MD PhD
Publikationsdatum: 01.06.2023
Verlag: Springer Medizin
Erschienen in: Herz / Ausgabe 5/2023
Print ISSN: 0340-9937
Elektronische ISSN: 1615-6692
DOI: https://doi.org/10.1007/s00059-023-05181-7

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Atrial fibrillation increases the risk of new-onset myocardial infarction amongst working-age population: a propensity-matched study