Ausgabe 1/2024
Inhalt (472 Artikel)
Development of search strategies for systematic reviews in health using ChatGPT: a critical analysis
Nathalia Sernizon Guimarães, Julliane Vasconcelos Joviano-Santos, Marcela Gomes Reis, Roberta Rayra Martins Chaves
Small-molecule agonist AdipoRon alleviates diabetic retinopathy through the AdipoR1/AMPK/EGR4 pathway
Yihan Wang, Yujuan Liu, Junwei Fang, Xindan Xing, Hanying Wang, Xin Shi, Xinyi Liu, Tian Niu, Kun Liu
Recent advances of engineered oncolytic viruses-based combination therapy for liver cancer
Junhe Zhang, Yunxi Xiao, Jie Zhang, Yun Yang, Liao Zhang, Fan Liang
Impact of NQO1 dysregulation in CNS disorders
Li Yuhan, Maryam Khaleghi Ghadiri, Ali Gorji
PIGT promotes cell growth, glycolysis, and metastasis in bladder cancer by modulating GLUT1 glycosylation and membrane trafficking
Mingyue Tan, Qi Pan, Chao Yu, Xinyu Zhai, Jianyi Gu, Le Tao, Dongliang Xu
TC2N inhibits distant metastasis and stemness of breast cancer via blocking fatty acid synthesis
Xiang-lin Hao, Yang-fan Lv, De-feng Li, Fu-hai Bai, Ji Gong, Guang-qiang Pan, Lin-xi Su, Ya-li Wang, Wan-lei Fu, Bo Liu, Lu Huang, Dong Yan, Qiu-lin Tan, Jin-yi Liu, Qiao-nan Guo
Potential roles of the interactions between gut microbiota and metabolites in LPS-induced intrauterine inflammation (IUI) and associated preterm birth (PTB)
Bei Jia, Lijun Tang, Huibing Liu, Wenqian Chen, Qian Chen, Mei Zhong, Ailan Yin
Bladder cancer risk stratification with the Oncuria 10-plex bead-based urinalysis assay using three different Luminex xMAP instrumentation platforms
Hideki Furuya, Toru Sakatani, Sunao Tanaka, Kaoru Murakami, Richard T. Waldron, Wayne Hogrefe, Charles J. Rosser
The SOX4/EZH2/SLC7A11 signaling axis mediates ferroptosis in calcium oxalate crystal deposition-induced kidney injury
Xinzhou Yan, Yuqi Xia, Bojun Li, Zehua Ye, Lei Li, Tianhui Yuan, Baofeng Song, Weimin Yu, Ting Rao, Jinzhuo Ning, Fangyou Lin, Shuqin Mei, Zhiguo Mao, Xiangjun Zhou, Wei Li, Fan Cheng
Causal effects of gut microbiota on sepsis and sepsis-related death: insights from genome-wide Mendelian randomization, single-cell RNA, bulk RNA sequencing, and network pharmacology
Sha Yang, Jing Guo, Zhuo Kong, Mei Deng, Jingjing Da, Xin Lin, Shuo Peng, Junwu Fu, Tao Luo, Jun Ma, Hao Yin, Lin Liu, Jian Liu, Yan Zha, Ying Tan, Jiqin Zhang
Function and mechanism of GBP1 in the development and progression of cervical cancer
Senyu Wang, Yajing Zhang, Xiumin Ma, Yangchun Feng
NCAPG2 promotes prostate cancer malignancy and stemness via STAT3/c-MYC signaling
Enchong Zhang, Zhengjie Chen, Wangmin Liu, Lin Lin, Lina Wu, Johnny Guan, Jianfeng Wang, Chuize Kong, Jianbin Bi, Mo Zhang
AIM2 promotes irradiation resistance, migration ability and PD-L1 expression through STAT1/NF-κB activation in oral squamous cell carcinoma
Hui-Wen Chiu, Hsin-Lun Lee, Hsun-Hua Lee, Hsiao-Wei Lu, Kent Yu-Hsien Lin, Yuan-Feng Lin, Che-Hsuan Lin
Virus-like particle-mediated delivery of structure-selected neoantigens demonstrates immunogenicity and antitumoral activity in mice
Ana Barajas, Pep Amengual-Rigo, Anna Pons-Grífols, Raquel Ortiz, Oriol Gracia Carmona, Victor Urrea, Nuria de la Iglesia, Juan Blanco-Heredia, Carla Anjos-Souza, Ismael Varela, Benjamin Trinité, Ferran Tarrés-Freixas, Carla Rovirosa, Rosalba Lepore, Miguel Vázquez, Leticia de Mattos-Arruda, Alfonso Valencia, Bonaventura Clotet, Carmen Aguilar-Gurrieri, Victor Guallar, Jorge Carrillo, Julià Blanco
Predictive, preventive, and personalized medicine in breast cancer: targeting the PI3K pathway
Muhammad Tufail, Jia-Ju Hu, Jie Liang, Cai-Yun He, Wen-Dong Wan, Yu-Qi Huang, Can-Hua Jiang, Hong Wu, Ning Li
On the use of receiver operating characteristic curve analysis to determine the most appropriate p value significance threshold
Farrokh Habibzadeh
Red blood cell-derived arginase release in hemolytic uremic syndrome
Niklas Friberg, Ida Arvidsson, Ashmita Tontanahal, Ann-Charlotte Kristoffersson, Magnus Gram, Bernard S. Kaplan, Diana Karpman
Risk factors for carotid plaque formation in type 2 diabetes mellitus
Jin Chen, Wenwen Li, Jingzhu Cao, Yuhan Lu, Chaoqun Wang, Jin Lu
Trophoblast-derived miR-410-5p induces M2 macrophage polarization and mediates immunotolerance at the fetal-maternal interface by targeting the STAT1 signaling pathway
Jing Yang, Longfei Li, Linlin Wang, Ruizhi Chen, Xiaobing Yang, Juanhua Wu, Gang Feng, Jinli Ding, Lianghui Diao, Jiao Chen, Jing Yang
Correction: YangZheng XiaoJi exerts anti-tumour growth effects by antagonising the effects of HGF and its receptor, cMET, in human lung cancer cells
Wen G. Jiang, Lin Ye, Fiona Ruge, Sioned Owen, Tracey Martin, Ping‑Hui Sun, Andrew J. Sanders, Jane Lane, Lucy Satherley, Hoi P. Weeks, Yong Gao, Cong Wei, Yiling Wu, Malcolm D. Mason
TIMELESS promotes reprogramming of glucose metabolism in oral squamous cell carcinoma
Yafan Chen, Zhengyang Han, Le Zhang, Caihong Gao, Jingyi Wei, Xuyuan Yang, Yabing Han, Yunbo Li, Chunmei Zhang, Yixin Wei, Jiaqi Dong, Wenxing Xun, Weifu Sun, Taotao Zhang, Hui Zhang, Jingtao Chen, Peng Yuan
Racial differences in length of stay and readmission for asthma in the all of us research program
Esteban Correa-Agudelo, Yadu Gautam, Angelico Mendy, Tesfaye B. Mersha
ChemR23 signaling ameliorates brain injury via inhibiting NLRP3 inflammasome-mediated neuronal pyroptosis in ischemic stroke
Lan Liu, Jiawei Zhang, Kaili Lu, Yaxuan Zhang, Xiaofeng Xu, Jiangshan Deng, Xiaojie Zhang, Haibing Zhang, Yuwu Zhao, Xiuzhe Wang
Transcriptomic insights into UTUC: role of inflammatory fibrosis and potential for personalized treatment
Keqiang Li, Zhenlin Huang, Guoqing Xie, Budeng Huang, Liang Song, Yu Zhang, Jinjian Yang
Translational medicine for acute lung injury
Jianguo Zhang, Yumeng Guo, Michael Mak, Zhimin Tao
(Pro)renin receptor mediates tubular epithelial cell pyroptosis in diabetic kidney disease via DPP4-JNK pathway
Shiying Xie, Shicong Song, Sirui Liu, Qiong Li, Wei Zou, Jianting Ke, Cheng Wang
Spatial features of specific CD103+CD8+ tissue-resident memory T cell subsets define the prognosis in patients with non-small cell lung cancer
Guanqun Yang, Siqi Cai, Mengyu Hu, Chaozhuo Li, Liying Yang, Wei Zhang, Jujie Sun, Fenghao Sun, Ligang Xing, Xiaorong Sun
Noninvasive electrical stimulation as a neuroprotective strategy in retinal diseases: a systematic review of preclinical studies
Jiaxian Li, Wei Zhou, Lina Liang, Yamin Li, Kai Xu, Xiaoyu Li, Ziyang Huang, Yu Jin
Comprehensive genomic profiling on metastatic Melanoma: results from a network screening from 7 Italian Cancer Centres
Matteo Pallocca, Ivan Molineris, Enrico Berrino, Benedetta Marcozzi, Martina Betti, Lauretta Levati, Stefania D’Atri, Chiara Menin, Gabriele Madonna, Paola Ghiorzo, Jenny Bulgarelli, Virgina Ferraresi, Tiziana Venesio, Monica Rodolfo, Licia Rivoltini, Luisa Lanfrancone, Paolo Antonio Ascierto, Luca Mazzarella, Pier Giuseppe Pelicci, Ruggero De Maria, Gennaro Ciliberto, Enzo Medico, Giandomenico Russo
PLOD3 facilitated T cell activation in the colorectal tumor microenvironment and liver metastasis by the TNF-α/ NF-κB pathway
Min Ding, Cheng Wang, Junhong Hu, Junjun She, Ruoyu Shi, Yixuan Liu, Qi Sun, Haojun Xu, Guoren Zhou, Wenlan Wu, Hongping Xia
LIPCAR levels in plasma-derived extracellular vesicles is associated with left ventricle remodeling post-myocardial infarction
Annie Turkieh, Olivia Beseme, Ouriel Saura, Henri Charrier, Jean-Baptiste Michel, Philippe Amouyel, Thomas Thum, Christophe Bauters, Florence Pinet
Myeloid leukemia-derived galectin-1 downregulates CAR expression to hinder cytotoxicity of CAR T cells
Chuo Li, Shiyu Zuo, Lingling Shan, Huifang Huang, Haidong Cui, Xiaoming Feng
The spike-specific TCRβ repertoire shows distinct features in unvaccinated or vaccinated patients with SARS-CoV-2 infection
Eleonora Vecchio, Salvatore Rotundo, Claudia Veneziano, Antonio Abatino, Ilenia Aversa, Raffaella Gallo, Caterina Giordano, Francesca Serapide, Paolo Fusco, Giuseppe Viglietto, Giovanni Cuda, Francesco Costanzo, Alessandro Russo, Enrico Maria Trecarichi, Carlo Torti, Camillo Palmieri
Central 5-HTergic hyperactivity induces myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS)-like pathophysiology
Jin-Seok Lee, Ji-Yun Kang, Samuel-Young Park, Seung-Ju Hwang, Sung-Jin Bae, Chang-Gue Son
Novel cellular systems unveil mucosal melanoma initiating cells and a role for PI3K/Akt/mTOR pathway in mucosal melanoma fitness
Matilde Monti, Luisa Benerini Gatta, Mattia Bugatti, Irene Pezzali, Sara Picinoli, Marcello Manfredi, Antonio Lavazza, Virginia Vita Vanella, Veronica De Giorgis, Lucia Zanatta, Francesco Missale, Silvia Lonardi, Benedetta Zanetti, Giovanni Bozzoni, Moris Cadei, Andrea Abate, Barbara Vergani, Piera Balzarini, Simonetta Battocchio, Carla Facco, Mario Turri-Zanoni, Paolo Castelnuovo, Piero Nicolai, Ester Fonsatti, Biagio Eugenio Leone, Emilio Marengo, Sandra Sigala, Roberto Ronca, Michela Perego, Davide Lombardi, William Vermi
Correction: Epithelial cell adhesion molecule (EpCAM) regulates HGFR signaling to promote colon cancer progression and metastasis
Chi-Chiu Lee, Chia-Jui Yu, Sushree Shankar Panda, Kai-Chi Chen, Kang-Hao Liang, Wan-Chen Huang, Yu-Shiuan Wang, Pei-Chin Ho, Han-Chung Wu
Single-cell transcriptome sequencing reveals aberrantly activated inter-tumor cell signaling pathways in the development of clear cell renal cell carcinoma
Junfeng Zhang, Fuzhong Liu, Wenjia Guo, Xing Bi, Shuai Yuan, Fuerhaiti Shayiti, Ting Pan, Kailing Li, Peng Chen
DEL-1: a promising treatment for AMD-associated ER stress in retinal pigment epithelial cells
ChangHyuk Kwon, Wonjun Cho, Sung Woo Choi, Heeseung Oh, A. M. Abd El-Aty, Ibrahim Gecili, Ji Hoon Jeong, Tae Woo Jung
Expression of HLA-DR by mesenchymal stromal cells in the platelet lysate era: an obsolete release criterion for MSCs?
Zyrafete Kuçi, Natascha Piede, Kathrin Vogelsang, Lisa-Marie Pfeffermann, Sibylle Wehner, Emilia Salzmann-Manrique, Miriam Stais, Hermann Kreyenberg, Halvard Bonig, Peter Bader, Selim Kuçi
Dietary sulfur amino acid restriction in humans with overweight and obesity: a translational randomized controlled trial
Thomas Olsen, Emma Stolt, Bente Øvrebø, Amany Elshorbagy, Elena C. Tore, Sindre Lee-Ødegård, Hannibal Troensegaard, Hanna Johannessen, Beate Doeland, Anna A. D. Vo, Anja F. Dahl, Karianne Svendsen, Magne Thoresen, Helga Refsum, Russell Rising, Kristýna Barvíková, Marleen van Greevenbroek, Viktor Kožich, Kjetil Retterstøl, Kathrine J. Vinknes
Post-translational protein lactylation modification in health and diseases: a double-edged sword
Hang Gong, Huang Zhong, Long Cheng, Liang-Ping Li, De-Kui Zhang
Multi-institutional prognostic modeling of survival outcomes in NSCLC patients treated with first-line immunotherapy using radiomics
Sevinj Yolchuyeva, Leyla Ebrahimpour, Marion Tonneau, Fabien Lamaze, Michele Orain, François Coulombe, Julie Malo, Wiam Belkaid, Bertrand Routy, Philippe Joubert, Venkata SK. Manem
Targeting the SphK1/S1P/PFKFB3 axis suppresses hepatocellular carcinoma progression by disrupting glycolytic energy supply that drives tumor angiogenesis
Xin Tracy Liu, Yu Huang, Da Liu, Yingxin Celia Jiang, Min Zhao, Long Hoa Chung, Xingxing Daisy Han, Yinan Zhao, Jinbiao Chen, Paul Coleman, Ka Ka Ting, Collin Tran, Yingying Su, Claude Vincent Dennis, Atul Bhatnagar, Ken Liu, Anthony Simon Don, Mathew Alexander Vadas, Mark Douglas Gorrell, Shubiao Zhang, Michael Murray, Mary Meltem Kavurma, Geoffrey William McCaughan, Jennifer Ruth Gamble, Yanfei Qi
Sex-differences in Mediterranean diet: a key piece to explain sex-related cardiovascular risk in obesity? A cross-sectional study
Luigi Barrea, Ludovica Verde, Rosario Suárez, Evelyn Frias-Toral, Celina Andrade Vásquez, Annamaria Colao, Silvia Savastano, Giovanna Muscogiuri
DNTGF-βR armored CAR-T cell therapy against tumors from bench to bedside
Yuning Wang, Guo Zhao, Shuhang Wang, Ning Li
ANGPTL4 accelerates ovarian serous cystadenocarcinoma carcinogenesis and angiogenesis in the tumor microenvironment by activating the JAK2/STAT3 pathway and interacting with ESM1
Yu-kun Li, An-bo Gao, Tian Zeng, Dan Liu, Qun-feng Zhang, Xiao-min Ran, Zhen-zi Tang, Yan Li, Jue Liu, Ting Zhang, Gang-qing Shi, Wen-chao Zhou, Wen-da Zou, Juan Peng, Juan Zhang, Hui Li, Juan Zou
Circular RNA hsa_circ_0050386 suppresses non-small cell lung cancer progression via regulating the SRSF3/FN1 axis
Jinbin Chen, Boqi Rao, Zeqin Huang, Chen Xie, Yonghui Yu, Binyao Yang, Di Wu, Dedong Wang, Fuman Qiu, Yifeng Zhou, Yibin Deng, Jiachun Lu
Single-cell sequencing reveals the heterogeneity of B cells and tertiary lymphoid structures in muscle-invasive bladder cancer
Hao Yuan, Xingning Mao, Yunkun Yan, Rong Huang, Qingyun Zhang, Yanyu Zeng, Mengying Bao, Yan Dai, Bo Fang, Junhao Mi, Yuli Xie, Xiang Wang, Haiying Zhang, Zengnan Mo, Rirong Yang
Improved cognition after rifaximin treatment is associated with changes in intra- and inter-brain network functional connectivity
Franc Casanova-Ferrer, Juan-José Gallego, Alessandra Fiorillo, Amparo Urios, María-Pilar Ríos, José Luis León, María-Pilar Ballester, Desamparados Escudero-García, Elena Kosenko, Vicente Belloch, Carmina Montoliu
CVD phenotyping in oncologic disorders: cardio-miRNAs as a potential target to improve individual outcomes in revers cardio-oncology
Ming Yang, Tiepeng Li, Shujin Guo, Kangping Song, Chuhui Gong, Ning Huang, Dejiang Pang, Hengyi Xiao
Lung nodule malignancy classification with associated pulmonary fibrosis using 3D attention-gated convolutional network with CT scans
Yucheng Liu, Hao Yun Hsu, Tiffany Lin, Boyu Peng, Anjali Saqi, Mary M. Salvatore, Sachin Jambawalikar
Klf10 is involved in extracellular matrix calcification of chondrocytes alleviating chondrocyte senescence
Rong Peng, Jie Shang, Ning Jiang, Hsu Chi-Jen, Yu Gu, Baizhou Xing, Renan Hu, Biao Wu, Dawei Wang, Xianghe Xu, Huading Lu
Brain-targeted delivery of neuroprotective survival gene minimizing hematopoietic cell contamination: implications for Parkinson’s disease treatment
Min Hak Lee, Sukyeong Kang, Ki-Hwan Um, Seok Won Lee, Hyorin Hwang, Kyunghwa Baek, Jin Woo Choi
MicroRNA-93-5p regulates odontogenic differentiation and dentin formation via KDM6B
Si Wu, Xin Xu, Shiqi Gao, Sibei Huo, Mian Wan, Xin Zhou, Xuedong Zhou, Liwei Zheng, Yachuan Zhou
Metabolic reprogramming based on RNA sequencing of gemcitabine-resistant cells reveals the FASN gene as a therapeutic for bladder cancer
Lijie Zhou, Kaixuan Du, Yiheng Dai, Youmiao Zeng, Yongbo Luo, Mengda Ren, Wenbang Pan, Yuanhao Liu, Lailai Zhang, Ronghui Zhu, Dapeng Feng, Fengyan Tian, Chaohui Gu
Whole-orbit radiomics: machine learning-based multi- and fused- region radiomics signatures for intravenous glucocorticoid response prediction in thyroid eye disease
Haiyang Zhang, Mengda Jiang, Hoi Chi Chan, Huijie Zhang, Jiashuo Xu, Yuting Liu, Ling Zhu, Xiaofeng Tao, Duojin Xia, Lei Zhou, Yinwei Li, Jing Sun, Xuefei Song, Huifang Zhou, Xianqun Fan
Integrating single-cell and bulk RNA sequencing data unveils antigen presentation and process-related CAFS and establishes a predictive signature in prostate cancer
Wenhao Wang, Tiewen Li, Zhiwen Xie, Jing Zhao, Yu Zhang, Yuan Ruan, Bangmin Han
Melatonin as an immunomodulator in CD19-targeting CAR-T cell therapy: managing cytokine release syndrome
Na Zheng, Yihao Long, Zixuan Bai, Jianing Li, Hongyu Wang, Dan-Dan Song, Hong-Lin Liu, Jian-Hong Shi, Shuli Zhao
Intracellular delivery of Parkin-RING0-based fragments corrects Parkin-induced mitochondrial dysfunction through interaction with SLP-2
Alessandra Zanon, Marianna Guida, Alexandros A. Lavdas, Corrado Corti, Maria Paulina Castelo Rueda, Alessandro Negro, Peter P. Pramstaller, Francisco S. Domingues, Andrew A. Hicks, Irene Pichler
Gastroesophageal reflux disease and the risk of respiratory diseases: a Mendelian randomization study
Rui Dong, Qianqian Zhang, Hongxing Peng
Inhibition of soluble epoxide hydrolase enhances the dentin-pulp complex regeneration mediated by crosstalk between vascular endothelial cells and dental pulp stem cells
Lingwenyao Kong, Juanjuan Li, Yuwen Bai, Shaoyang Xu, Lin Zhang, Weixian Chen, Lu Gao, Fu Wang
Tumor-associated macrophages in colorectal cancer metastasis: molecular insights and translational perspectives
Siyu Hou, Yuanchun Zhao, Jiajia Chen, Yuxin Lin, Xin Qi
MicroRNA-218-5p-Ddx41 axis restrains microglia-mediated neuroinflammation through downregulating type I interferon response in a mouse model of Parkinson’s disease
Danlei Wang, Hongling Gao, Qixiong Qin, Jingyi Li, Jingwei Zhao, Yi Qu, Jiangting Li, Yongjie Xiong, Zhe Min, Zhijuan Mao, Zheng Xue
Integrative network analysis suggests prioritised drugs for atopic dermatitis
Antonio Federico, Lena Möbus, Zeyad Al-Abdulraheem, Alisa Pavel, Vittorio Fortino, Giusy del Giudice, Harri Alenius, Nanna Fyhrquist, Dario Greco
A benchmarking framework for the accurate and cost-effective detection of clinically-relevant structural variants for cancer target identification and diagnosis
Guiwu Zhuang, Xiaotao Zhang, Wenjing Du, Libin Xu, Jiyong Ma, Haitao Luo, Hongzhen Tang, Wei Wang, Peng Wang, Miao Li, Xu Yang, Dongfang Wu, Shencun Fang
Construction of an ER stress-related prognostic signature for predicting prognosis and screening the effective anti-tumor drug in osteosarcoma
Weidong Chen, Yan Liao, Pengxiao Sun, Jian Tu, Yutong Zou, Ji Fang, Ziyun Chen, Hongbo Li, Junkai Chen, Yuzhong Peng, Lili Wen, Xianbiao Xie
Comparison of lung cancer occurring in fibrotic versus non-fibrotic lung on chest CT
Mary M. Salvatore, Yucheng Liu, Boyu Peng, Hao Yun Hsu, Anjali Saqi, Wei-Yann Tsai, Cheng-Shiun Leu, Sachin Jambawalikar
Pharmacological and cell-based treatments to increase local skin flap viability in animal models
Charlotte E. Berry, Thalia Le, Nicholas An, Michelle Griffin, Micheal Januszyk, Carter B. Kendig, Alexander Z. Fazilat, Andrew A. Churukian, Phoebe M. Pan, Derrick C. Wan
Immunogram defines four cancer-immunity cycle phenotypes with distinct clonal selection patterns across solid tumors
Ying Hu, Huaibo Sun, Wei Shi, Chen Chen, Xueying Wu, Yu Jiang, Guoying Zhang, Na Li, Jin Song, Hao Zhang, Baiyong Shen, Hui Zeng, Henghui Zhang
Vein wall thickness and severity of pulmonary involvement due to sars n-cov2 virus infection
Gennaro Quarto, Giacomo Benassai, Annamaria Colao, Antonio Cittadini, Paolo Antonio Ascierto, Rosario Pivonello, Andrea Elefante, Marialuisa Bocchino, Alberto Maria Marra, Ivan Gentile, Gianluca Benassai, Andrea Miletti, Francesca Calemma, Ermenegildo Furino, Cristina Angelis, Davide Menafra, Francesco Garifalos, Giovanni Domenico De Palma, Maria Carmela Annunziata, Maria Teresa Cantelli, Paola Nappa, Marina Vastarella, Chiara Simeoli, Michele Castoro, Nunzia Verde, Agnese Giaccone, Laura Reynaud, Antonio Riccardo Buonomo, Biagio Pinchera, Chiara Graziadio, Emanuele Filice, Roberta Modica, Rosa Pirchio, Federica Giardino, Roberta D’Assante, Ivo Iavicoli, Luca Fontana, Veruscka Leso, Caterina Nocera, Guido Iaccarino, Antonio Bianco, Eugenio Vaia, Fiore Manganelli, Lucia Ruggiero, Dario Zoppi, Fabio Tortora, Sirio Cocozza, Mario Tortora, Giovanna Muscogiuri, Luigi Barrea, Claudia Vetrani, Alessandro Sanduzzi Zamparelli, Anna Buonocore, Lorena Gallotti, Mauro Mormile, Andrea Bartolomeis, Felice Iasevoli, Annarita Barone, Simone Maurea, Arnaldo Stanzione, Martina Caruso, Claudia Bombace, Maria Triassi, Maddalena Illario, Lorenzo Mercurio, Vincenzo de Luca
New advances of the androgen receptor in prostate cancer: report from the 1st International Androgen Receptor Symposium
Sherif Mehralivand, Christian Thomas, Martin Puhr, Frank Claessens, Arjanneke F. van de Merbel, Anna Dubrovska, Guido Jenster, Christof Bernemann, Ulrich Sommer, Holger H. H. Erb
Unraveling the underlying pathogenic factors driving nonalcoholic steatohepatitis and hepatocellular carcinoma: an in-depth analysis of prognostically relevant gene signatures in hepatocellular carcinoma
Yuan Ni, Maoqing Lu, Ming Li, Xixi Hu, Feng Li, Yan Wang, Dong Xue
MTFR2-dependent mitochondrial fission promotes HCC progression
La Zhang, Xiuzhen Zhang, Haichuan Liu, Changhong Yang, Jiyao Yu, Wei Zhao, Jiao Guo, Baoyong Zhou, Ning Jiang
Hypoxia-induced P4HA1 overexpression promotes post-ischemic angiogenesis by enhancing endothelial glycolysis through downregulating FBP1
Yating Xu, Di Xia, Kai Huang, Minglu Liang
Clinical and genetic risk factors underlying severe consequence identified in 75 families with unilateral high myopia
Yi Jiang, Xueshan Xiao, Wenmin Sun, Yingwei Wang, Shiqiang Li, Xiaoyun Jia, Panfeng Wang, J. Fielding Hejtmancik, Qingjiong Zhang
MRI radiomics to monitor therapeutic outcome of sorafenib plus IHA transcatheter NK cell combination therapy in hepatocellular carcinoma
Guangbo Yu, Zigeng Zhang, Aydin Eresen, Qiaoming Hou, Emilie Elizabeth Garcia, Zeyang Yu, Nadine Abi-Jaoudeh, Vahid Yaghmai, Zhuoli Zhang
Selective SERCA2a activator as a candidate for chronic heart failure therapy
Martina Arici, Shih-Che Hsu, Mara Ferrandi, Paolo Barassi, Carlotta Ronchi, Eleonora Torre, Andrea Luraghi, Gwo-Jyh Chang, Patrizia Ferrari, Giuseppe Bianchi, Francesco Peri, Antonio Zaza, Marcella Rocchetti
Activation of mucosal insulin receptor exacerbates intestinal inflammation by promoting tissue resident memory T cells differentiation through EZH2
Teming Li, Ben Han, Liucan Wang, Lihua Sun, Yujiao Cai, Min Yu, Weidong Xiao, Hua Yang
Multi-omics integration with weighted affinity and self-diffusion applied for cancer subtypes identification
Xin Duan, Xinnan Ding, Zhuanzhe Zhao
Exploring the predictive power of jejunal microbiome composition in clinical and subclinical necrotic enteritis caused by Clostridium perfringens: insights from a broiler chicken model
Hemlata Gautam, Lisanework E. Ayalew, Noor Ahmad Shaik, Iresha Subhasinghe, Shelly Popowich, Betty Chow-Lockerbie, Alexa Dixon, Khawaja Ashfaque Ahmed, Suresh K. Tikoo, Susantha Gomis
Evaluating the long-term impact of COVID-19-associated public health interventions on zoonotic and vector-borne diseases in China: an interrupted time series analysis
Yongbin Wang, Siyu Qing, Xianxiang Lan, Lun Li, Peiping Zhou, Yue Xi, Ziyue Liang, Chenguang Zhang, Chunjie Xu
(+)-Lipoic acid reduces mitochondrial unfolded protein response and attenuates oxidative stress and aging in an in vitro model of non-alcoholic fatty liver disease
Lucia Longhitano, Alfio Distefano, Nicolò Musso, Paolo Bonacci, Laura Orlando, Sebastiano Giallongo, Daniele Tibullo, Simona Denaro, Giuseppe Lazzarino, Jessica Ferrigno, Anna Nicolosi, Amer M. Alanazi, Federico Salomone, Emanuela Tropea, Ignazio Alberto Barbagallo, Vincenzo Bramanti, Giovanni Li Volti, Giacomo Lazzarino, Daniele Torella, Angela Maria Amorini
Causal relationship between multiple sclerosis and cortical structure: a Mendelian randomization study
Dongren Sun, Rui Wang, Qin Du, Ying Zhang, Hongxi Chen, Ziyan Shi, Xiaofei Wang, Hongyu Zhou
The integration of multidisciplinary approaches revealed PTGES3 as a novel drug target for breast cancer treatment
Qinan Yin, Haodi Ma, Yirui Dong, Shunshun Zhang, Junxiang Wang, Jing Liang, Longfei Mao, Li Zeng, Xin Xiong, Xingang Chen, Jingjing Wang, Xuewei Zheng
Matrix stiffness affects tumor-associated macrophage functional polarization and its potential in tumor therapy
Jiaqiang Xiong, Rourou Xiao, Jiahui Zhao, Qiuyan Zhao, Manwen Luo, Feng Li, Wei Zhang, Meng Wu
Integrating network pharmacology and animal experimental validation to investigate the action mechanism of oleanolic acid in obesity
Tianfeng Liu, Jiliang Wang, Ying Tong, Lele Wu, Ying Xie, Ping He, Shujue Lin, Xuguang Hu
A novel sub-regional radiomics model to predict immunotherapy response in non-small cell lung carcinoma
Jie Peng, Dan Zou, Xudong Zhang, Honglian Ma, Lijie Han, Biao Yao
Prognostic and predictive value of super-enhancer-derived signatures for survival and lung metastasis in osteosarcoma
Guanyu Huang, Xuelin Zhang, Yu Xu, Shuo Chen, Qinghua Cao, Weihai Liu, Yiwei Fu, Qiang Jia, Jingnan Shen, Junqiang Yin, Jiajun Zhang
Intestinal microbiota and metabolome perturbations in ischemic and idiopathic dilated cardiomyopathy
Yusheng Wang, Yandan Xie, Gehendra Mahara, Yanling Xiong, Yalan Xiong, Qifang Zheng, Jianqin Chen, Wei Zhang, Honghao Zhou, Qing Li
A novel biomarker associated with EBV infection improves response prediction of immunotherapy in gastric cancer
Xiaoqin Li, Fen Xiong, Zhangmin Hu, Qing Tao, Yufei Yang, Xuehan Qiao, Chen Peng, Yuchun Jiang, Miao Han, Kebin Dong, Yi Hua, Wei Zhang, Min Xu, Weiguo Long, Yichuan Xiao, Deqiang Wang
Causal relationship between gut microbiota and gastrointestinal diseases: a mendelian randomization study
Kaiwen Wu, Qiang Luo, Ye Liu, Aoshuang Li, Demeng Xia, Xiaobin Sun
Hypoxia upregulating ACSS2 enhances lipid metabolism reprogramming through HMGCS1 mediated PI3K/AKT/mTOR pathway to promote the progression of pancreatic neuroendocrine neoplasms
Danyang Gu, Mujie Ye, Guoqin Zhu, Jianan Bai, Jinhao Chen, Lijun Yan, Ping Yu, Feiyu Lu, Chunhua Hu, Yuan Zhong, Pengfei Liu, Qibin He, Qiyun Tang
A systematic two-sample and bidirectional MR process highlights a unidirectional genetic causal effect of allergic diseases on COVID-19 infection/severity
Xiao-tong Chen, Shuai Zhi, Xin-yu Han, Jian-wei Jiang, Guang-ming Liu, Shi-tao Rao
Inhibitor of PD-1/PD-L1: a new approach may be beneficial for the treatment of idiopathic pulmonary fibrosis
Jie Tan, Qianfei Xue, Xiao Hu, Junling Yang
Association between the systemic immune inflammation index and periodontitis: a cross-sectional study
Junfeng Guo, Rufu Xu, Rongxing Liu, Wenjing Lai, Changpeng Hu, Haitao He, Gang Zhang, Guobing Li, Weiwei Zheng, Rong Zhang
Emerging applications of single-cell profiling in precision medicine of atherosclerosis
Huiling Lin, Ming Zhang, Mi Hu, Yangkai Zhang, WeiWei Jiang, Wanying Tang, Yuxin Ouyang, Liping Jiang, Yali Mi, Zhi Chen, Pingping He, Guojun Zhao, Xinping Ouyang
The gut microbiota participates in the effect of linaclotide in patients with irritable bowel syndrome with constipation (IBS-C): a multicenter, prospective, pre-post study
Jianyun Zhou, Haoqi Wei, An Zhou, Xu Xiao, Xia Xie, Bo Tang, Hui Lin, Li Tang, Ruiping Meng, Xiaoying Yuan, Jing Zhang, Cheng Huang, Baobao Huang, Xiping Liao, Tingting Zhong, Suyu He, Sai Gu, Shiming Yang
Fbxw7 suppresses carcinogenesis and stemness in triple-negative breast cancer through CHD4 degradation and Wnt/β-catenin pathway inhibition
Guodong Xiao, Weiping Lu, Jing Yuan, Zuyue Liu, Peili Wang, Huijie Fan
Asthma prediction via affinity graph enhanced classifier: a machine learning approach based on routine blood biomarkers
Dejing Li, Stanley Ebhohimhen Abhadiomhen, Dongmei Zhou, Xiang-Jun Shen, Lei Shi, Yubao Cui
SARS-CoV-2 neurovascular invasion supported by Mendelian randomization
Yiji Pan, Jun Zhang, Tao He
Synergistic use of anti-inflammatory ketorolac and gentamicin to target staphylococcal biofilms
Amita Sekar, Dmitry Gil, Peyton Tierney, Madeline McCanne, Vikram Daesety, Darina Trendafilova, Orhun K. Muratoglu, Ebru Oral
Association of the pathomics-collagen signature with lymph node metastasis in colorectal cancer: a retrospective multicenter study
Wei Jiang, Huaiming Wang, Xiaoyu Dong, Yandong Zhao, Chenyan Long, Dexin Chen, Botao Yan, Jiaxin Cheng, Zexi Lin, Shuangmu Zhuo, Hui Wang, Jun Yan
EXO1/P53/SREBP1 axis-regulated lipid metabolism promotes prostate cancer progression
Zefeng Wang, Zheng Chao, Qi Wang, Fan Zou, Tianbao Song, Lizhe Xu, Jinzhuo Ning, Fan Cheng
Current evidence regarding the cellular mechanisms associated with cancer progression due to cardiovascular diseases
Tanawat Attachaipanich, Siriporn C. Chattipakorn, Nipon Chattipakorn
Molecular epidemiology of pregnancy using omics data: advances, success stories, and challenges
Ali Rahnavard, Ranojoy Chatterjee, Hui Wen, Clark Gaylord, Sabina Mugusi, Kevin C. Klatt, Emily R. Smith
Immune-related lncRNAs signature and radiomics signature predict the prognosis and immune microenvironment of glioblastoma multiforme
Jixin Luan, Di Zhang, Bing Liu, Aocai Yang, Kuan Lv, Pianpian Hu, Hongwei Yu, Amir Shmuel, Chuanchen Zhang, Guolin Ma
Combination of mutations in genes controlling DNA repair and high mutational load plays a prognostic role in pancreatic ductal adenocarcinoma (PDAC): a retrospective real-life study in Sardinian population
Maria Cristina Sini, Maria Grazia Doro, Laura Frogheri, Angelo Zinellu, Panagiotis Paliogiannis, Alberto Porcu, Fabrizio Scognamillo, Daniele Delogu, Davide Adriano Santeufemia, Ivana Persico, Grazia Palomba, Giovanni Battista Maestrale, Antonio Cossu, Giuseppe Palmieri
Single-nucleus transcriptomic analysis reveals the relationship between gene expression in oligodendrocyte lineage and major depressive disorder
Yinping Xie, Lijuan Chen, Leimin Wang, Tongou Liu, Yage Zheng, Lujia Si, Hailong Ge, Hong Xu, Ling Xiao, Gaohua Wang
Measurement of cumulative high-sensitivity C-reactive protein and monocyte to high-density lipoprotein ratio in the risk prediction of type 2 diabetes: a prospective cohort study
Dan Wu, Genyuan Chen, Yulong Lan, Shuohua Chen, Xiong Ding, Chiju Wei, Lois Balmer, Wei Wang, Shouling Wu, Wencan Xu
Unraveling metagenomics through long-read sequencing: a comprehensive review
Chankyung Kim, Monnat Pongpanich, Thantrira Porntaveetus
Exosomal miR-361-3p promotes the viability of breast cancer cells by targeting ETV7 and BATF2 to upregulate the PAI-1/ERK pathway
Yao Li, Lei Fan, An Yan, Xiaotian Ren, Yanyang Zhao, Bin Hua
m6A methylation-mediated regulation of LncRNA MEG3 suppresses ovarian cancer progression through miR-885-5p and the VASH1 pathway
Yan Li, Shenghan Lou, Jian Zhang, Shilu Zhao, Ge Lou
Tirzepatide prevents neurodegeneration through multiple molecular pathways
Rosaria Anna Fontanella, Puja Ghosh, Ada Pesapane, Fatemeh Taktaz, Armando Puocci, Martina Franzese, Maria Federica Feliciano, Giovanni Tortorella, Lucia Scisciola, Eduardo Sommella, Concetta Ambrosino, Giuseppe Paolisso, Michelangela Barbieri
Exosomes: potential targets for the diagnosis and treatment of neuropsychiatric disorders
Haorao Li, Yanling Yuan, Qinglian Xie, Zaiquan Dong
Exploration of a hypoxia-immune-related microenvironment gene signature and prediction model for hepatitis C-induced early-stage fibrosis
Chuwen Chen, Haozheng Cai, Junyi Shen, Xiaoyun Zhang, Wei Peng, Chuan Li, Haopeng Lv, Tianfu Wen
PITPNC1 Suppress CD8+ T cell immune function and promote radioresistance in rectal cancer by modulating FASN/CD155
Junxian Liang, Limin Liao, Lang Xie, WenWen Tang, Xiang Yu, Yinghao Lu, Hongzhen Chen, Juanli Xu, Lei Sun, Huanmei Wu, Chunhui Cui, Yujing Tan
Correction to: Increased co-expression of PD1 and TIM3 is associated with poor prognosis and immune microenvironment heterogeneity in gallbladder cancer
Xing He, Yaorong Peng, Gui He, Huilin Ye, Liqiang Liu, Qixian Zhou, Juanyi Shi, Sha Fu, Jie Wang, Zhenyu Zhou, Wenbin Li
Circulating vitamin D level before initiating chemotherapy impacts on the time-to-outcome in metastatic colorectal cancer patients: systematic review and meta-analysis
Alessandro Ottaiano, Maria Lucia Iacovino, Mariachiara Santorsola, Sergio Facchini, Domenico Iervolino, Francesco Perri, Guglielmo Nasti, Vincenzo Quagliariello, Nicola Maurea, Andrea Ronchi, Bianca Arianna Facchini, Alessia Bignucolo, Massimiliano Berretta
New insights on collagen structural organization and spatial distribution around dental implants: a comparison between machined and laser-treated surfaces
Alessia Belloni, Giulio Argentieri, Giulia Orilisi, Valentina Notarstefano, Elisabetta Giorgini, Gianmaria D’Addazio, Giovanna Orsini, Sergio Caputi, Bruna Sinjari
A novel online calculator based on clinical features and hematological parameters to predict total skin clearance in patients with moderate to severe psoriasis
Yuxiong Jiang, Dawei Huang, Qianyu Chen, Yingyuan Yu, Yifan Hu, Yu Wang, Rongfen Chen, Lingling Yao, Xiaoyuan Zhong, Luyang Kong, Qian Yu, Jiajing Lu, Ying Li, Yuling Shi
Adverse clinical outcomes and immunosuppressive microenvironment of RHO-GTPase activation pattern in hepatocellular carcinoma
Qi Yang, Zewei Zhuo, Xinqi Qiu, Ruibang Luo, Kehang Guo, Huihuan Wu, Rui Jiang, Jingwei Li, Qizhou Lian, Pengfei Chen, Weihong Sha, Hao Chen
The occurrence and development mechanisms of esophageal stricture: state of the art review
Fang Yang, Yiwei Hu, Zewen Shi, Mujie Liu, Kefeng Hu, Guoliang Ye, Qian Pang, Ruixia Hou, Keqi Tang, Yabin Zhu
Plasma fibroblast activation protein is decreased in acute heart failure despite cardiac tissue upregulation
Marta Delgado-Arija, Patricia Genovés, Lorena Pérez-Carrillo, Irene González-Torrent, Isaac Giménez-Escamilla, Luis Martínez-Dolz, Manuel Portolés, Estefanía Tarazón, Esther Roselló-Lletí
Changes in microbial composition and interaction patterns of female urogenital tract and rectum in response to HPV infection
Yong-Hong Dong, Yu-Hua Luo, Chen-Jian Liu, Wen-Yu Huang, Lin Feng, Xing-Yuan Zou, Jin-Yan Zhou, Xiao-Ran Li
Repurposing of Zika virus live-attenuated vaccine (ZIKV-LAV) strains as oncolytic viruses targeting human glioblastoma multiforme cells
Carla Bianca Luena Victorio, Wisna Novera, Arun Ganasarajah, Joanne Ong, Melisyaa Thomas, Jonas Wu, Hilary Si Yin Toh, Alfred Xuyang Sun, Eng Eong Ooi, Ann-Marie Chacko
Prediction of complete regression in fertility-sparing patients with endometrial cancer and apical hyperplasia: the GLOBAL model in a large Chinese cohort
Xingchen Li, Yiqin Wang, Jiaqi Wang, Yuan Fan, Jianliu Wang
DNMT3L inhibits hepatocellular carcinoma progression through DNA methylation of CDO1: insights from big data to basic research
Xiaokai Yan, Yao Qi, Xinyue Yao, Nanjing Zhou, Xinxin Ye, Xing Chen
Several implications for the pathogenesis and treatment of thrombosis in PNH patients according to multiomics analysis
Yingying Chen, Xiaorui Meng, Yinxing Wang, Chunyan Liu, Rong Fu
Harnessing the potential of HLA-G in cancer therapy: advances, challenges, and prospects
Siyuan Wang, Jiaxin Wang, Yu Xia, Le Zhang, Yueqiang Jiang, Man Liu, Qinglei Gao, Cuntai Zhang
Pathogenomics for accurate diagnosis, treatment, prognosis of oncology: a cutting edge overview
Xiaobing Feng, Wen Shu, Mingya Li, Junyu Li, Junyao Xu, Min He
Integrating cfDNA liquid biopsy and organoid-based drug screening reveals PI3K signaling as a promising therapeutic target in colorectal cancer
Huan Yang, Xing Xiao, Leli Zeng, Haiteng Zeng, Yueyuan Zheng, Jingshu Wang, Guanghua Li, Weigang Dai, Yulong He, Suihai Wang, Jianjun Peng, Wei Chen
Wnt/β-catenin signalling activates IMPDH2-mediated purine metabolism to facilitate oxaliplatin resistance by inhibiting caspase-dependent apoptosis in colorectal cancer
Yuting Huang, Szehoi Chan, Shuna Chen, Xueqi Liu, Miao Li, Liyuan Zheng, Zhaoxia Dong, Ziyi Yang, Zixuan Liu, Disheng Zhou, Xingding Zhang, Bo Zhang
Single-cell transcriptome analysis reveals immunosuppressive landscape in overweight and obese colorectal cancer
Guozhong Xiao, Yihui Zheng, Huaxian Chen, Minyi Luo, Chaoxin Yang, Donglin Ren, Pengfei Qin, Heng Zhang, Hongcheng Lin
Tumor mutational burden predictability in head and neck squamous cell carcinoma patients treated with immunotherapy: systematic review and meta-analysis
Juan P. Rodrigo, Mario Sánchez-Canteli, María Otero-Rosales, Pablo Martínez-Camblor, Francisco Hermida-Prado, Juana M. García-Pedrero
Standardizing digital biobanks: integrating imaging, genomic, and clinical data for precision medicine
Valentina Brancato, Giuseppina Esposito, Luigi Coppola, Carlo Cavaliere, Peppino Mirabelli, Camilla Scapicchio, Rita Borgheresi, Emanuele Neri, Marco Salvatore, Marco Aiello
The siRNA-mediated knockdown of AP-1 restores the function of the pulmonary artery and the right ventricle by reducing perivascular and interstitial fibrosis and key molecular players in cardiopulmonary disease
Ioana Karla Comarița, Gabriela Tanko, Iliuță Laurențiu Anghelache, Adriana Georgescu
Genetic evidence of the causal relationship between chronic liver diseases and musculoskeletal disorders
Zhengjie Lu, Xuefei Li, Yongjian Qi, Bin Li, Liaobin Chen
The mechanistic functional landscape of retinitis pigmentosa: a machine learning-driven approach to therapeutic target discovery
Marina Esteban-Medina, Carlos Loucera, Kinza Rian, Sheyla Velasco, Lorena Olivares-González, Regina Rodrigo, Joaquin Dopazo, Maria Peña-Chilet
Ensemble methods of rank-based trees for single sample classification with gene expression profiles
Min Lu, Ruijie Yin, X. Steven Chen
Cancer testis antigen burden (CTAB): a novel biomarker of tumor-associated antigens in lung cancer
R. J. Seager, Maria-Fernanda Senosain, Erik Van Roey, Shuang Gao, Paul DePietro, Mary K. Nesline, Durga Prasad Dash, Shengle Zhang, Heidi Ko, Stephanie B. Hastings, Kyle C. Strickland, Rebecca A. Previs, Taylor J. Jensen, Marcia Eisenberg, Brian J. Caveney, Eric A. Severson, Shakti Ramkissoon, Jeffrey M. Conroy, Sarabjot Pabla
Analysis of differences in intestinal flora associated with different BMI status in colorectal cancer patients
Yongqi Huang, Xiaoliang Huang, Zhen Wang, Fuhai He, Zigui Huang, Chuanbin Chen, Binzhe Tang, Mingjian Qin, Yongzhi Wu, Chenyan Long, Weizhong Tang, Xianwei Mo, Jungang Liu
Enhanced molecular release from elderly bone samples using collagenase I: insights into fatty acid metabolism alterations
Amir Mohammad Malvandi, Esra Halilaj, Martina Faraldi, Laura Mangiavini, Simone Cristoni, Valerio Leoni, Giovanni Lombardi
COSMIC-based mutation database enhances identification efficiency of HLA-I immunopeptidome
Fangzhou Wang, Zhenpeng Zhang, Mingsong Mao, Yudai Yang, Ping Xu, Shichun Lu
High-fat and high-sucrose diet impairs female reproduction by altering ovarian transcriptomic and metabolic signatures
Congcong Liu, Yunde Dou, Mengge Zhang, Shan Han, Shourui Hu, Yuxuan Li, Zhiheng Yu, Yue Liu, Xiaofan Liang, Zi-Jiang Chen, Han Zhao, Yuqing Zhang
The application of time-to-event analysis in machine learning prognostic models
Zi-He Peng, Zhi-Xin Huang, Juan-Hua Tian, Tie Chong, Zhao-Lun Li
Emerging evidence linking stress and glucocorticoid signaling with cancer phenotypes
Anthony S. Zannas
ROS-mediated up-regulation of SAE1 by Helicobacter pylori promotes human gastric tumor genesis and progression
Liu Shi, Jianfang Shangguan, Ying Lu, Jianfang Rong, Qinyu Yang, Yihan Yang, Chuan Xie, Xu Shu
Very low-calorie ketogenic diet (VLCKD) in the management of hidradenitis suppurativa (Acne Inversa): an effective and safe tool for improvement of the clinical severity of disease. Results of a pilot study
Ludovica Verde, Sara Cacciapuoti, Giuseppina Caiazzo, Matteo Megna, Fabrizio Martora, Annarita Cavaliere, Maria Mattera, Maria Maisto, Gian Carlo Tenore, Annamaria Colao, Silvia Savastano, Giovanna Muscogiuri, Luigi Barrea
Comparison of standard mismatch repair deficiency and microsatellite instability tests in a large cancer series
Maja L. Nádorvári, István Kenessey, András Kiss, Tamás Barbai, Janina Kulka, Erzsébet Rásó, József Tímár
From the identification of actionable molecular targets to the generation of faithful neuroblastoma patient-derived preclinical models
Mario Capasso, Chiara Brignole, Vito A. Lasorsa, Veronica Bensa, Sueva Cantalupo, Enrico Sebastiani, Alessandro Quattrone, Eleonora Ciampi, Marianna Avitabile, Angela R. Sementa, Katia Mazzocco, Barbara Cafferata, Gabriele Gaggero, Valerio G. Vellone, Michele Cilli, Enzo Calarco, Elena Giusto, Patrizia Perri, Sanja Aveic, Doriana Fruci, Annalisa Tondo, Roberto Luksch, Rossella Mura, Marco Rabusin, Francesco De Leonardis, Monica Cellini, Paola Coccia, Achille Iolascon, Maria V. Corrias, Massimo Conte, Alberto Garaventa, Loredana Amoroso, Mirco Ponzoni, Fabio Pastorino
Development and validation of a novel scoring system for acute ischemic stroke
Rui Xu, Shixin Peng, Yulong Qiu, Ji Zhu, Xiaodong Zhang, Li Jiang
Recent advances of m6A methylation in skeletal system disease
Jianhui Liang, Qian Yi, Yang Liu, Jiachen Li, Zecheng Yang, Wei Sun, Weichao Sun
Tubulointerstitial nephritis antigen-like 1 from cancer-associated fibroblasts contribute to the progression of diffuse-type gastric cancers through the interaction with integrin β1
Dagyeong Lee, In-Hye Ham, Hye Jeong Oh, Dong Min Lee, Jung Hwan Yoon, Sang-Yong Son, Tae-Min Kim, Jae-Young Kim, Sang-Uk Han, Hoon Hur
Fucoidan modulates SIRT1 and NLRP3 to alleviate hypertensive retinopathy: in vivo and in vitro insights
Jing Li, Xiaochen Wang, Jie Bai, Huangzhao Wei, Wenbo Wang, Shuai Wang
Autophagy inhibition improves the targeted radionuclide therapy efficacy of 131I-FAP-2286 in pancreatic cancer xenografts
Xingyu Liu, Danni Li, Tianbao Ma, Xiu Luo, Ye Peng, Tao Wang, Changjing Zuo, Jianming Cai
Exploring the role of ubiquitin regulatory X domain family proteins in cancers: bioinformatics insights, mechanisms, and implications for therapy
Enyu Yang, Xiaowei Fan, Haihan Ye, Xiaoyang Sun, Qing Ji, Qianyun Ding, Shulian Zhong, Shuo Zhao, Cheng Xuan, Meiyu Fang, Xianfeng Ding, Jun Cao
Potential crosstalk between SPP1 + TAMs and CD8 + exhausted T cells promotes an immunosuppressive environment in gastric metastatic cancer
Yan Du, Yilin Lin, Lin Gan, Shuo Wang, Shuang Chen, Chen Li, Sen Hou, Bozhi Hu, Bo Wang, Yingjiang Ye, Zhanlong Shen
High CD133 expression in proximal tubular cells in diabetic kidney disease: good or bad?
Yuhan Zhang, Lusi Xu, Congcong Guo, Xianzhi Li, Yutian Tian, Lin Liao, Jianjun Dong
Association between modifiable lifestyle factors and telomere length: a univariable and multivariable Mendelian randomization study
Miao Chen, Zhen Wang, Hongfei Xu, Peng Teng, Weidong Li, Liang Ma
Endothelium-specific deletion of p62 causes organ fibrosis and cardiac dysfunction
Jing Feng, Yan Li, Yu Zhang, Shengnan Sun, Jian Sun, Quanlin Xu, Xingzhao Ji, Yi Liu, Qiang Wan
Technological Vanguard: the outstanding performance of the LTY-CNN model for the early prediction of epileptic seizures
Yang Yang, Tianyun Luan, Zhangjun Yu, Min Zhang, Fengtian Li, Xing Chen, Fei Gao, Zhijun Zhang
A single-domain antibody for the detection of pathological Tau protein in the early stages of oligomerization
Nicolas De Leiris, Pascale Perret, Charlotte Lombardi, Bülent Gözel, Sabine Chierici, Philippe Millet, Marlène Debiossat, Sandrine Bacot, Benjamin B. Tournier, Patrick Chames, Jean-Luc Lenormand, Catherine Ghezzi, Daniel Fagret, Marcelle Moulin
A novel complement C3 inhibitor CP40-KK protects against experimental pulmonary arterial hypertension via an inflammasome NLRP3 associated pathway
Lei Dai, Yu Chen, Jinhua Wu, Zhen He, Yueqi Zhang, Wenjun Zhang, Yang Xie, Hesong Zeng, Xiaodan Zhong
Association between dietary vitamin B1 intake and cognitive function among older adults: a cross-sectional study
Weiai Jia, Hemei Wang, Chao Li, Jingpu Shi, Fangfang Yong, Huiqun Jia
Prevention of neointimal hyperplasia after coronary artery bypass graft via local delivery of sirolimus and rosuvastatin: network pharmacology and in vivo validation
Ji-yeon Ryu, Eui Hwa Jang, JiYong Lee, Jung-Hwan Kim, Young-Nam Youn
Intranasal delivery of mitochondria targeted neuroprotective compounds for traumatic brain injury: screening based on pharmacological and physiological properties
Jignesh D. Pandya, Sudeep Musyaju, Hiren R. Modi, Starlyn L. Okada-Rising, Zachary S. Bailey, Anke H. Scultetus, Deborah A. Shear
Engineered bone marrow mesenchymal stem cell-derived exosomes loaded with miR302 through the cardiomyocyte specific peptide can reduce myocardial ischemia and reperfusion (I/R) injury
Jianjun Gu, Jia You, Hao Liang, Jiacai Zhan, Xiang Gu, Ye Zhu
Solobacterium moorei promotes the progression of adenomatous polyps by causing inflammation and disrupting the intestinal barrier
Shoujuan Yu, Xifan Wang, Ziyang Li, Dekui Jin, Mengyang Yu, Jingnan Li, Yixuan Li, Xiaoxue Liu, Qi Zhang, Yinghua Liu, Rong Liu, Xiaoyu Wang, Bing Fang, Chengying Zhang, Ran Wang, Fazheng Ren
RBBP7, regulated by SP1, enhances the Warburg effect to facilitate the proliferation of hepatocellular carcinoma cells via PI3K/AKT signaling
Yuan Fang, WeiQiang Tang, Siming Qu, ZhiTao Li, XiaoLi Zhang, YingLei Miao, Zhong Zeng, HanFei Huang
Combined therapy of CAR-IL-15/IL-15Rα-T cells and GLIPR1 knockdown in cancer cells enhanced anti-tumor effect against gastric cancer
Jianbin Ye, Qiaoyuan Liu, Yunxuan He, Zhenkun Song, Bao Lin, Zhiwei Hu, Juanyuan Hu, Yunshan Ning, Cheguo Cai, Yan Li
Gut microbial metabolites SCFAs and chronic kidney disease
Meng He, Wenqian Wei, Yichen Zhang, Zhouxia Xiang, Dan Peng, Ayijiaken Kasimumali, Shu Rong
The innovative checkpoint inhibitors of lung adenocarcinoma, cg09897064 methylation and ZBP1 expression reduction, have implications for macrophage polarization and tumor growth in lung cancer
Ailing Wang, Wei-sha Zheng, Zhen Luo, Lian Bai, Shi Zhang
Diffuse large B-cell lymphoma: the significance of CD8+ tumor-infiltrating lymphocytes exhaustion mediated by TIM3/Galectin-9 pathway
Qiqi Zhu, Yiming Yang, Kexin Chen, Qiaoyu Zhang, Yifan Huang, Shunhai Jian
Multi-omic profiling reveals associations between the gut microbiome, host genome and transcriptome in patients with colorectal cancer
Shaomin Zou, Chao Yang, Jieping Zhang, Dan Zhong, Manqi Meng, Lu Zhang, Honglei Chen, Lekun Fang
Senescent fibroblast facilitates re-epithelization and collagen deposition in radiation-induced skin injury through IL-33-mediated macrophage polarization
Yan Chen, Le Ma, Zhuo Cheng, Zhihe Hu, Yang Xu, Jie Wu, Yali Dai, Chunmeng Shi
Autoinducer-2 promotes the colonization of Lactobacillus rhamnosus GG to improve the intestinal barrier function in a neonatal mouse model of antibiotic-induced intestinal dysbiosis
Riqiang Hu, Ting Yang, Qing Ai, Yuan Shi, Yanchun Ji, Qian Sun, Bei Tong, Jie Chen, Zhengli Wang
HuR promotes castration-resistant prostate cancer progression by altering ERK5 activation via posttranscriptional regulation of BCAT1
Hang You, Guojing Song, Zhizhen Xu, Saipeng Chen, Wenhao Shen, Heting Liu, Bingqian Deng, Jun Li, Gang Huang
Exploring the interplay of gut microbiota, inflammation, and LDL-cholesterol: a multiomics Mendelian randomization analysis of their causal relationship in acute pancreatitis and non-alcoholic fatty liver disease
Congzhi Yan, Jingxia Bao, Jinji Jin
Advances in free fatty acid profiles in gestational diabetes mellitus
Haoyi Du, Danyang Li, Laura Monjowa Molive, Na Wu
Expanding the reach of commercial cell therapies requires changes at medical centers
David F. Stroncek, Nan Zhang, Jiaqiang Ren, Rob Somerville, Anh Dinh
DeepRisk network: an AI-based tool for digital pathology signature and treatment responsiveness of gastric cancer using whole-slide images
Mengxin Tian, Zhao Yao, Yufu Zhou, Qiangjun Gan, Leihao Wang, Hongwei Lu, Siyuan Wang, Peng Zhou, Zhiqiang Dai, Sijia Zhang, Yihong Sun, Zhaoqing Tang, Jinhua Yu, Xuefei Wang
An angel or a devil? Current view on the role of CD8+ T cells in the pathogenesis of myasthenia gravis
Yong Peng, Huan Yang, Quan Chen, Hong Jin, Ya-hui Xue, Miao-qiao Du, Shu Liu, Shun-yu Yao
High somatic mutations in circulating tumor DNA predict response of metastatic pancreatic ductal adenocarcinoma to first-line nab-paclitaxel plus S-1: prospective study
Lei Huang, Yao Lv, Shasha Guan, Huan Yan, Lu Han, Zhikuan Wang, Quanli Han, Guanghai Dai, Yan Shi
Clinical data mining: challenges, opportunities, and recommendations for translational applications
Huimin Qiao, Yijing Chen, Changshun Qian, You Guo
Characterizing hub biomarkers for post-transplant renal fibrosis and unveiling their immunological functions through RNA sequencing and advanced machine learning techniques
Xinhao Niu, Cuidi Xu, Yin Celeste Cheuk, Xiaoqing Xu, Lifei Liang, Pingbao Zhang, Ruiming Rong
Multi-modal assessment of a cardiac stem cell therapy reveals distinct modulation of regional scar properties
Moritz Schweins, Ralf Gäbel, Matti Raitza, Praveen Vasudevan, Heiko Lemcke, Markus Joksch, Anna Schildt, Jens Kurth, Tobias Lindner, Felix G. Meinel, Alper Öner, Hüseyin Ince, Brigitte Vollmar, Bernd Joachim Krause, Robert David, Cajetan Immanuel Lang
A proteomic classifier panel for early screening of colorectal cancer: a case control study
Hanju Hua, Tingting Wang, Liangxuan Pan, Xiaoyao Du, Tianxue Xia, Zhenzhong Fa, Lei Gu, Fei Gao, Chaohui Yu, Feng Gao, Lujian Liao, Zhe Shen
Genomic and transcriptomic profiling of combined small-cell lung cancer through microdissection: unveiling the transformational pathway of mixed subtype
Wenjuan Ma, Ting Zhou, Mengmeng Song, Jiaqing Liu, Gang Chen, Jianhua Zhan, Liyan Ji, Fan Luo, Xuan Gao, Pansong Li, Xuefeng Xia, Yan Huang, Li Zhang
A community challenge to predict clinical outcomes after immune checkpoint blockade in non-small cell lung cancer
Mike Mason, Óscar Lapuente-Santana, Anni S. Halkola, Wenyu Wang, Raghvendra Mall, Xu Xiao, Jacob Kaufman, Jingxin Fu, Jacob Pfeil, Jineta Banerjee, Verena Chung, Han Chang, Scott D. Chasalow, Hung Ying Lin, Rongrong Chai, Thomas Yu, Francesca Finotello, Tuomas Mirtti, Mikko I. Mäyränpää, Jie Bao, Emmy W. Verschuren, Eiman I. Ahmed, Michele Ceccarelli, Lance D. Miller, Gianni Monaco, Wouter R. L. Hendrickx, Shimaa Sherif, Lin Yang, Ming Tang, Shengqing Stan Gu, Wubing Zhang, Yi Zhang, Zexian Zeng, Avinash Das Sahu, Yang Liu, Wenxian Yang, Davide Bedognetti, Jing Tang, Federica Eduati, Teemu D. Laajala, William J. Geese, Justin Guinney, Joseph D. Szustakowski, Benjamin G. Vincent, David P. Carbone
Fatigue and symptom-based clusters in post COVID-19 patients: a multicentre, prospective, observational cohort study
Merel E. B. Cornelissen, Lizan D. Bloemsma, Anouk W. Vaes, Nadia Baalbaki, Qichen Deng, Rosanne J. H. C. G. Beijers, Lieke C. E. Noij, Laura Houweling, Somayeh Bazdar, Martijn A. Spruit, Anke H. Maitland-van der Zee
ZSWIM4 inhibition improves chemosensitivity in epithelial ovarian cancer cells by suppressing intracellular glycine biosynthesis
Kunxiang Gong, Yinger Huang, Yanqin Zheng, Wenbo Hao, Kun Shi
Ubiquitin-specific protease 14 targets PFKL-mediated glycolysis to promote the proliferation and migration of oral squamous cell carcinoma
Xingming Zhang, Lou Geng, Yi Tang, Yingying Wang, Youping Zhang, Chujiao Zhu, Hu Lei, Hanzhang Xu, Qi Zhu, Yingli Wu, Wenli Gu
Rab32 facilitates Schwann cell pyroptosis in rats following peripheral nerve injury by elevating ROS levels
Jiayi Wang, Pin Chen, Guanjie Han, Yongjie Zhou, Xingdong Xiang, Mengxuan Bian, Lei Huang, Xiang Wang, Binfeng He, Shunyi Lu
From pixels to patient care: deep learning-enabled pathomics signature offers precise outcome predictions for immunotherapy in esophageal squamous cell cancer
Butuo Li, Wenru Qin, Linlin Yang, Haoqian Li, Chao Jiang, Yueyuan Yao, Shuping Cheng, Bing Zou, Bingjie Fan, Taotao Dong, Linlin Wang
ACACA reduces lipid accumulation through dual regulation of lipid metabolism and mitochondrial function via AMPK- PPARα- CPT1A axis
Jian Dong, Muzi Li, Runsheng Peng, Yuchuan Zhang, Zilin Qiao, Na Sun
Adaptation of a standardized lifestyle intervention to maximize health outcomes in adolescent metabolic and bariatric surgery patients
Maral Misserian, Alicia Wheelington, Rashon King, Jackson Francis, M. Sunil Mathew, Marlyn A. Allicock, Bethany R. Cartwright, Adejumoke Adewunmi, Aparajita Chandrasekhar, Dhatri Polavarapu, Faisal G. Qureshi, Sarah E. Barlow, Sarah E. Messiah
Magnetic resonance imaging-based approaches for detecting the efficacy of combining therapy following VEGFR-2 and PD-1 blockade in a colon cancer model
Xi Xu, Mengjie Ma, Kunlin Ye, Dong Zhang, Xinhui Chen, Jiayang Wu, Xukai Mo, Zeyu Xiao, Changzheng Shi, Liangping Luo
Inhibition of ferroptosis reverses heart failure with preserved ejection fraction in mice
Yixiao Xiong, Xin Liu, Ling Jiang, Tao Hao, Yanyan Wang, Tao Li
Acute venous thromboembolism plasma and red blood cell metabolomic profiling reveals potential new early diagnostic biomarkers: observational clinical study
Cláudia Febra, Joana Saraiva, Fátima Vaz, João Macedo, Hamza Mohammad Al-Hroub, Mohammad Harb Semreen, Rui Maio, Vitor Gil, Nelson Soares, Deborah Penque
Cytosolic Cadherin 4 promotes angiogenesis and metastasis in papillary thyroid cancer by suppressing the ubiquitination/degradation of β-catenin
Luyao Wu, Jian Xiao, Dandan Yi, Haoran Ding, Ru Wang, Zehua Duan, Zhijian Liu, Xianbiao Shi, Meiping Shen, Jianfeng Sang
Altered gut mycobiome in patients with end-stage renal disease and its correlations with serum and fecal metabolomes
Yi Ren, Lei Chen, Ruochun Guo, Shiyang Ma, Shenghui Li, Yue Zhang, Hongli Jiang, Haitao Shi, Pan Zhang
Decoding the transcriptional heterogeneity, differentiation lineage, clinical significance in tissue-resident memory CD8 T cell of the small intestine by single-cell analysis
Jialing Fang, Jun Lei, Boxiao He, Yankang Wu, Peng Chen, Zaiqiao Sun, Ning Wu, Yafei Huang, Pengcheng Wei, Lei Yin, Yongshun Chen
RGS6 drives cardiomyocyte death following nucleolar stress by suppressing Nucleolin/miRNA-21
Abhishek Singh Sengar, Manish Kumar, Chetna Rai, Sreemoyee Chakraborti, Dinesh Kumar, Pranesh Kumar, Sukhes Mukherjee, Kausik Mondal, Adele Stewart, Biswanath Maity
Association of dietary flavonoid intakes with prevalence of chronic respiratory diseases in adults
Runmiao Wu, Xu Zhu, Gongchang Guan, Qianwei Cui, Ling Zhu, Yujie Xing, Jingsha Zhao
Integrative single-cell transcriptomic analyses reveal the cellular ontological and functional heterogeneities of primary and metastatic liver tumors
Menghui Gui, Shilin Huang, Shizhou Li, Yuying Chen, Furong Cheng, Yulin Liu, Ji-ao Wang, Yuting Wang, Rui Guo, Yiming Lu, Pengbo Cao, Gangqiao Zhou
Emerging roles of circular RNAs in tumorigenesis, progression, and treatment of gastric cancer
Qiang Ma, Feifei Yang, Bin Xiao, Xiaolan Guo
Targeting of mitochondrial fission through natural flavanones elicits anti-myeloma activity
Roberta Torcasio, Maria Eugenia Gallo Cantafio, Claudia Veneziano, Carmela De Marco, Ludovica Ganino, Ilenia Valentino, Maria Antonietta Occhiuzzi, Ida Daniela Perrotta, Teresa Mancuso, Filomena Conforti, Bruno Rizzuti, Enrica Antonia Martino, Massimo Gentile, Antonino Neri, Giuseppe Viglietto, Fedora Grande, Nicola Amodio
DLGAP5 promotes lung adenocarcinoma growth via upregulating PLK1 and serves as a therapeutic target
Maojian Chen, Shaoping Zhang, Fan Wang, Junyi He, Wei Jiang, Li Zhang
Metabolic heterogeneity in clear cell renal cell carcinoma revealed by single-cell RNA sequencing and spatial transcriptomics
Guanwen Yang, Jiangting Cheng, Jiayi Xu, Chenyang Shen, Xuwei Lu, Chang He, Jiaqi Huang, Minke He, Jie Cheng, Hang Wang
A multi-dimensional approach to unravel the intricacies of lactylation related signature for prognostic and therapeutic insight in colorectal cancer
Huixia Huang, Keji Chen, Yifei Zhu, Zijuan Hu, Yaxian Wang, Jiayu Chen, Yuxue Li, Dawei Li, Ping Wei
TBC1D5 reverses the capability of HIF-2α in tumor progression and lipid metabolism in clear cell renal cell carcinoma by regulating the autophagy
Yu Huang, Zhiyong Xiong, Jianjun Wang, Yafen Gao, Qi Cao, Decai Wang, Jian Shi, Zhixian Chen, Xiong Yang
Role of Hippo pathway dysregulation from gastrointestinal premalignant lesions to cancer
Giulia Schiavoni, Beatrice Messina, Stefano Scalera, Lorenzo Memeo, Cristina Colarossi, Marzia Mare, Giovanni Blandino, Gennaro Ciliberto, Giulia Bon, Marcello Maugeri-Saccà
Multi-omics approaches for drug-response characterization in primary biliary cholangitis and autoimmune hepatitis variant syndrome
Fan Yang, Leyu Zhou, Yi Shen, Xianglin Wang, Xiaoli Fan, Li Yang
Quality appraisal and descriptive analysis of clinical practice guidelines for self-managed non-pharmacological interventions of cardiovascular diseases: a systematic review
Yun Qian, Jing-Yu (Benjamin) Tan, Tao Wang, Daniel Bressington, Hong-Juan Zhou, Meng-Yuan Li, Xian-Liang Liu
Ubiquitylation of RUNX3 by RNA-binding ubiquitin ligase MEX3C promotes tumorigenesis in lung adenocarcinoma
Zelai He, Huijun Zhang, Haibo Xiao, Xiangyu Zhang, Hongbo Xu, Ruifen Sun, Siwen Li
Correction: Excitatory neurons in the lateral parabrachial nucleus mediate the interruptive effect of inflammatory pain on a sustained attention task
Huan-Yu Zheng, Yu-Meng Chen, Yao Xu, Cheng Cen, Yun Wang
Neutrophil CD64 index as a new early predictive biomarker for infected pancreatic necrosis in acute pancreatitis
Xiangping Huang, Ling Wu, Qianhui Ouyang, Ying Huang, Lanhui Hong, Sixiang Liu, Kongzhi Yang, Ding Ning, Chao Chao Tan
Deciphering the omicron variant: integrated omics analysis reveals critical biomarkers and pathophysiological pathways
Qianyue Yang, Zhiwei Lin, Mingshan Xue, Yueting Jiang, Libing Chen, Jiahong Chen, Yuhong Liao, Jiali Lv, Baojun Guo, Peiyan Zheng, Huimin Huang, Baoqing Sun
Gentulizumab, a novel anti-CD47 antibody with potent antitumor activity and demonstrates a favorable safety profile
Tao Wang, Si-Qin Wang, Yin-Xiao Du, Dan-Dan Sun, Chang Liu, Shuang Liu, Ying-Ying Sun, Hai-Long Wang, Chun-Sheng Zhang, Hai-Long Liu, Lei Jin, Xiao-Ping Chen
Thyroid hormone protects human lung epithelial cells from cold preservation and warm reperfusion-induced injury
Dejan Bojic, Tanroop Aujla, Junichi Sugihara, Aaron Wong, Shaf Keshavjee, Mingyao Liu
Gut microbiota dynamics and fecal SCFAs after colonoscopy: accelerating microbiome stabilization by Clostridium butyricum
Zhenhui Chen, Lu Yu, Jiaxin Liu, Jingjing Kong, Xiaoshi Deng, Xiaotong Guo, Jiamin Shan, Daixuan Zhou, Wendan Li, Yangfan Lin, Wanwen Huang, Weisen Zeng, Xinlong Shi, Yang Bai, Hongying Fan
Epigenetic remodeling to improve the efficacy of immunotherapy in human glioblastoma: pre-clinical evidence for development of new immunotherapy approaches
Maria Fortunata Lofiego, Francesca Piazzini, Francesca Pia Caruso, Francesco Marzani, Laura Solmonese, Emma Bello, Fabrizio Celesti, Maria Claudia Costa, Teresa Noviello, Roberta Mortarini, Andrea Anichini, Michele Ceccarelli, Sandra Coral, Anna Maria Di Giacomo, Michele Maio, Alessia Covre
3D-printed PCL framework assembling ECM-inspired multi-layer mineralized GO-Col-HAp microscaffold for in situ mandibular bone regeneration
Yanqing Yang, Huan He, Fang Miao, Mingwei Yu, Xixi Wu, Yuanhang Liu, Jie Fu, Junwei Chen, Liya Ma, Xiangru Chen, Ximing Peng, Zhen You, Chuchao Zhou
The clinical efficacy and safety of berberine in the treatment of non-alcoholic fatty liver disease: a meta-analysis and systematic review
Qilong Nie, Mingyang Li, Caiyang Huang, Yongwei Yuan, Qiuyan Liang, Xiaojun Ma, Tengyu Qiu, Jianhong Li
Conditional generative adversarial network driven radiomic prediction of mutation status based on magnetic resonance imaging of breast cancer
Zi Huai Huang, Lianghong Chen, Yan Sun, Qian Liu, Pingzhao Hu
Cell therapy for retinal degenerative disorders: a systematic review and three-level meta-analysis
Alireza Soltani Khaboushan, Negar Ebadpour, Mohammad Mehdi Johari Moghadam, Zahra Rezaee, Abdol-Mohammad Kajbafzadeh, Masoumeh Majidi Zolbin
Silencing PinX1 enhances radiosensitivity and antitumor-immunity of radiotherapy in non-small cell lung cancer
Jieping Qiu, Ying Xia, Yawei Bao, Jingjing Cheng, Lei Liu, Dong Qian
Advances in metabolic reprogramming of NK cells in the tumor microenvironment on the impact of NK therapy
Linxuan Miao, Chenglin Lu, Bin Zhang, Huili Li, Xu Zhao, Haoran Chen, Ying Liu, Xiaonan Cui
Therapeutic potential of mitochondrial transplantation in modulating immune responses post-cardiac arrest: a narrative review
Tomoaki Aoki, Yusuke Endo, Eriko Nakamura, Cyrus E. Kuschner, Jacob Kazmi, Parmeshar Singh, Tai Yin, Lance B. Becker, Kei Hayashida
Senescent cancer-associated fibroblasts facilitate tumor associated neutrophil recruitment suppressing tumor immunity
Dongqi Lin, Xiaoqian Zhai, Xinxin Qi, Qinghua Zhou, Yanyang Liu, Yiyun Lin, Jiewei Liu
Validation of the Meet-URO score in metastatic clear cell renal cell carcinoma patients receiving second or third-line tyrosine kinase inhibitors-immune checkpoint inhibitors combination therapy
Sike He, Haoyang Liu, Junru Chen, Hao Zeng
CDSKNNXMBD: a novel clustering framework for large-scale single-cell data based on a stable graph structure
Jun Ren, Xuejing Lyu, Jintao Guo, Xiaodong Shi, Ying Zhou, Qiyuan Li
CRISPR/Cas9-edited ROS1 + non-small cell lung cancer cell lines highlight differential drug sensitivity in 2D vs 3D cultures while reflecting established resistance profiles
Marc Terrones, Christophe Deben, Felicia Rodrigues-Fortes, Anne Schepers, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer
Keratinocyte-derived circulating microRNAs in extracellular vesicles: a novel biomarker of psoriasis severity and potential therapeutic target
Young Joon Park, Dong Chan Kim, Soo-Jin Lee, Han Seul Kim, Ji Young Pak, Junho Kim, Jae Youn Cheong, Eun-So Lee
Development and validation of a machine learning-based predictive model for assessing the 90-day prognostic outcome of patients with spontaneous intracerebral hemorrhage
Zhi Geng, Chaoyi Yang, Ziye Zhao, Yibing Yan, Tao Guo, Chaofan Liu, Aimei Wu, Xingqi Wu, Ling Wei, Yanghua Tian, Panpan Hu, Kai Wang
The interaction between intratumoral bacteria and metabolic distortion in hepatocellular carcinoma
Chen Xue, Xinyu Gu, Qingmiao Shi, Xiao Ma, Junjun Jia, Yuanshuai Su, Zhengyi Bao, Juan Lu, Lanjuan Li
Mitochondrial metabolism in neural stem cells and implications for neurodevelopmental and neurodegenerative diseases
C. Garone, F. De Giorgio, S. Carli
Spatial insights into immunotherapy response in non-small cell lung cancer (NSCLC) by multiplexed tissue imaging
James Monkman, Afshin Moradi, Joseph Yunis, Geoff Ivison, Aaron Mayer, Rahul Ladwa, Ken O’Byrne, Arutha Kulasinghe
MORN2 regulates the morphology and energy metabolism of mitochondria and is required for male fertility in mice
Yining Liu, Tongtong Li, Mingze Shi, Yanling Wan, Hanzhen Li, Mingyu Zhang, Ziqi Wang, Shiyu Wang, Yue Lv, Gang Lu, Hongbin Liu, Haobo Zhang, Tao Huang
Comparing anti-tumor and anti-self immunity in a patient with melanoma receiving immune checkpoint blockade
Shuming Chen, Tracee L. McMiller, Abha Soni, Farah Succaria, John-William Sidhom, Laura C. Cappelli, Livia A. Casciola-Rosen, Isaac R. Morales, Preethi Sankaran, Alan E. Berger, Julie Stein Deutsch, Qingfeng C. Zhu, Robert A. Anders, Jody E. Hooper, Drew M. Pardoll, Evan J. Lipson, Janis M. Taube, Suzanne L. Topalian
Sex-related differences in serum biomarker levels predict the activity and efficacy of immune checkpoint inhibitors in advanced melanoma and non-small cell lung cancer patients
Giulia Pasello, Aline S. C. Fabricio, Paola Del Bianco, Valentina Salizzato, Adolfo Favaretto, Luisa Piccin, Fable Zustovich, Alessio Fabozzi, Costanza De Rossi, Jacopo Pigozzo, Mattia De Nuzzo, Elia Cappelletto, Laura Bonanno, Dario Palleschi, Gian Luca De Salvo, Valentina Guarneri, Massimo Gion, Vanna Chiarion-Sileni
Integrative analysis of chromatin accessibility and transcriptome landscapes in the induction of peritoneal fibrosis by high glucose
Qiong Song, Pengbo Wang, Huan Wang, Meijing Pan, Xiujuan Li, Zhuan’e Yao, Wei Wang, Guangbo Tang, Sen Zhou
Prediction model for EBV infection following HLA haploidentical matched hematopoietic stem cell transplantation
Xun-Hong Cao, Ze-Ying Fan, Ying-Jun Chang, Lan-Ping Xu, Xiao-Hui Zhang, Xiao-Jun Huang, Xiang-Yu Zhao
WNT-inhibitory factor 1-mediated glycolysis protects photoreceptor cells in diabetic retinopathy
Bolin Chen, Jing Zou, Lihui Xie, Yinjun Cai, Bowen Li, Wei Tan, Jinhaohao Huang, Fangling Li, Huizhuo Xu
Impaired balance between neutrophil extracellular trap formation and degradation by DNases in COVID-19 disease
Geoffrey Garcia, Sylvie Labrouche-Colomer, Alexandre Duvignaud, Etienne Clequin, Charles Dussiau, David-Alexandre Trégouët, Denis Malvy, Renaud Prevel, Atika Zouine, Isabelle Pellegrin, Julien Goret, Maria Mamani-Matsuda, Antoine Dewitte, Chloe James
Characterization of the proteome of stable and unstable carotid atherosclerotic plaques using data-independent acquisition mass spectrometry
Zhichao Lai, Chaonan Wang, Xiaoyan Liu, Haidan Sun, Zhengguang Guo, Jiang Shao, Kang Li, Junye Chen, Jiaxian Wang, Xiangling Lei, Keqiang Shu, Yuyao Feng, Deqiang Kong, Wei Sun, Bao Liu
Inhibition of OGFOD1 by FG4592 confers neuroprotection by activating unfolded protein response and autophagy after ischemic stroke
Jian Xie, Yuan Zhang, Bin Li, Wen Xi, Yu Wang, Lu Li, Chenchen Liu, Ling Shen, Bing Han, Yan Kong, HongHong Yao, Zhijun Zhang
PLA2G4A and ACHE modulate lipid profiles via glycerophospholipid metabolism in platinum-resistant gastric cancer
Menglin Chen, Cancan Zhang, Huaizhi Li, Shanshan Zheng, Yaqi Li, Mengyun Yuan, Yuxuan Chen, Jian Wu, Qingmin Sun
Inducing expression of ICOS-L by oncolytic adenovirus to enhance tumor-specific bi-specific antibody efficacy
Neshat Saffarzadeh, Emelie Foord, Eoghan O’Leary, Rand Mahmoun, Thomas Birkballe Hansen, Victor Levitsky, Thomas Poiret, Michael Uhlin
CircGLIS3 promotes gastric cancer progression by regulating the miR-1343-3p/PGK1 pathway and inhibiting vimentin phosphorylation
Yongxin Zhang, Xiaofeng Wang, Wenwei Liu, Tianxiang Lei, Tang Qiao, Wei Feng, Wu Song
Association of domain-specific physical activity with albuminuria among prediabetes and diabetes: a large cross-sectional study
Bingquan Xiong, Yufan Wang, Juan He, Lisha Wang, Rui He, Min Zhu, Jiaxing Wang, Yingrui Li, Bin Liu, Kaihu Xiao, Qiang She
Integrated mRNA- and miRNA-sequencing analyses unveil the underlying mechanism of tobacco pollutant-induced developmental toxicity in zebrafish embryos
Jiasheng Chen, Yuxin Lin, Deyi Gen, Wanxian Chen, Rui Han, Hao Li, Shijie Tang, Shukai Zheng, Xiaoping Zhong
PTEN deficiency potentiates HBV-associated liver cancer development through augmented GP73/GOLM1
Fuqiang Huang, Jing Guo, Na Zhao, Mengjie Hou, Xiaochen Gai, Shuhui Yang, Pei Cai, Yanan Wang, Qian Ma, Qi Zhao, Li Li, Huayu Yang, Yanling Jing, Di Jin, Zhongdong Hu, Xiaojun Zha, Hongyang Wang, Yilei Mao, Fangming Liu, Hongbing Zhang
Identification and functional activity of Nik related kinase (NRK) in benign hyperplastic prostate
Weixiang He, Zelin Tian, Bingchen Dong, Yitong Cao, Wei Hu, Peng Wu, Lei Yu, Xinhua Zhang, Shanshan Guo
Multi-omics analysis of the gut microbiome and metabolites associated with the psychoneurological symptom cluster in children with cancer receiving chemotherapy
Jinbing Bai, Ronald Eldridge, Madelyn Houser, Melissa Martin, Christie Powell, Kathryn S. Sutton, Hye In Noh, Yuhua Wu, Thomas Olson, Konstantinos T. Konstantinidis, Deborah W. Bruner
Characterizing neuroinflammation and identifying prenatal diagnostic markers for neural tube defects through integrated multi-omics analysis
Wenshuang Wang, Yanhong Ji, Zhexu Dong, Zheran Liu, Shuang Chen, Lei Dai, Xiaolan Su, Qingyuan Jiang, Hongxin Deng
Incorporating genetic similarity of auxiliary samples into eGene identification under the transfer learning framework
Shuo Zhang, Zhou Jiang, Ping Zeng
Amino acid profile alteration in age-related atrial fibrillation
Yunying Huang, Qiuzhen Lin, Yong Zhou, Jiayi Zhu, Yingxu Ma, Keke Wu, Zuodong Ning, Zixi Zhang, Na Liu, Mohan Li, Yaozhong Liu, Tao Tu, Qiming Liu
HERVs may perform as the initial trigger for acquired aplastic anemia
Ting Wang, Nianbin Li, Heng Wu, Rong Fu
Proteomic analysis of mitochondria associated membranes in renal ischemic reperfusion injury
Yi Li, Hua-bin Wang, Jin-long Cao, Wen-jun Zhang, Hai-long Wang, Chang-hong Xu, Kun-peng Li, Yi Liu, Ji-rong Wang, Hua-lan Ha, Sheng-jun Fu, Li Yang
A strategy to pioneer key agent(s) in Cephalotaxus alkaloids against pan-cancer via filtering methodology based on integrated pharmacology
Ki-Kwang Oh, Sang-Jun Yoon, Jung-A Eom, Kyeong Jin Lee, Goo-Hyun Kwon, Dong Joon Kim, Ki-Tae Suk
ANGPTL3 is a novel HDL component that regulates HDL function
Longyan Yang, Yan Wang, Yongsong Xu, Kun Li, Ruili Yin, Lijie Zhang, Di Wang, Lingling Wei, Jianan Lang, Yanan Cheng, Lu Wang, Jing Ke, Dong Zhao
Exosomal circRNAs in the plasma serve as novel biomarkers for IPF diagnosis and progression prediction
Wenhua Gan, Wenwen Song, Yujuan Gao, Xuexue Zheng, Fengjuan Wang, Zirui Zhang, Ke Zen, Hongwei Liang, Xin Yan
Predicting long-term progression of Alzheimer’s disease using a multimodal deep learning model incorporating interaction effects
Yifan Wang, Ruitian Gao, Ting Wei, Luke Johnston, Xin Yuan, Yue Zhang, Zhangsheng Yu
Routine evaluation of HBV-specific T cell reactivity in chronic hepatitis B using a broad-spectrum T-cell epitope peptide library and ELISpot assay
Yandan Wu, Xiaotao Liu, Yuan Mao, Ruixue Ji, Lingzhi Xia, Zining Zhou, Yan Ding, Pinqing Li, Yu Zhao, Min Peng, Jie Qiu, Chuanlai Shen
Kynurenine in IDO1high cancer cell-derived extracellular vesicles promotes angiogenesis by inducing endothelial mitophagy in ovarian cancer
Xiang Ying, Xiaocui Zheng, Xiaoqian Zhang, Yujia Yin, Xipeng Wang
Systematic integration of molecular and clinical approaches in HCV-induced hepatocellular carcinoma
Ciniso Sylvester Shabangu, Wen-Hsiu Su, Chia-Yang Li, Ming-Lung Yu, Chia-Yen Dai, Jee-Fu Huang, Wan-Long Chuang, Shu-Chi Wang
Bacterial DnaK reduces the activity of anti-cancer drugs cisplatin and 5FU
Francesca Benedetti, Emmanuel F. Mongodin, Jonathan H. Badger, Arshi Munawwar, Ashley Cellini, Weirong Yuan, Giovannino Silvestri, Carl N. Kraus, Simone Marini, Chozha V. Rathinam, Marco Salemi, Hervé Tettelin, Robert C. Gallo, Davide Zella
Shifting the paradigm: engaging multicellular networks for cancer therapy
Joyce Hu, Paolo Ascierto, Alessandra Cesano, Volker Herrmann, Francesco M. Marincola
Investigation of the acute pathogenesis of spondyloarthritis/HLA-B27-associated anterior uveitis based on genome-wide association analysis and single-cell transcriptomics
Shuming Chen, Weidi Huang, Qiaoqian Wan, Zichun Tang, Xie Li, Fang Zeng, Shuyan Zheng, Zhuo Li, Xiao Liu
HBV DNA polymerase upregulates the transcription of PD-L1 and suppresses T cell activity in hepatocellular carcinoma
Yan Jia, Jianing Zhao, Chunqing Wang, Jing Meng, Liqing Zhao, Hongwei Yang, Xiaoqing Zhao
CAR T cells and T cells phenotype and function are impacted by glucocorticoid exposure with different magnitude
Thomas Poiret, Sara Vikberg, Esther Schoutrop, Jonas Mattsson, Isabelle Magalhaes
CD19/CD20 dual-targeted chimeric antigen receptor-engineered natural killer cells exhibit improved cytotoxicity against acute lymphoblastic leukemia
Na Yang, Caili Zhang, Yingchun Zhang, Yuting Fan, Jing Zhang, Xiaojin Lin, Ting Guo, Yangzuo Gu, Jieheng Wu, Jianmei Gao, Xing Zhao, Zhixu He
Impact of myelofibrosis on patients with myelodysplastic syndromes following allogeneic hematopoietic stem cell transplantation
Panpan Zhu, Xiaoyu Lai, Lizhen Liu, Jimin Shi, Jian Yu, Yanmin Zhao, Luxin Yang, Tingting Yang, Weiyan Zheng, Jie Sun, Wenjun Wu, Yi Zhao, Zhen Cai, He Huang, Yi Luo
Exosomal-miRNas expression and growth factors released by mononuclear cells of CLAD patients in response to extracorporeal photopheresis
Sara Bozzini, Eleonora Bozza, Cecilia Bagnera, Claudia Del Fante, Eugenio Barone, Simona De Vitis, Mara De Amici, Giorgia Testa, Stefania Croce, Chiara Valsecchi, Maria A Avanzini, Rosalia Cacciatore, Cristina Mortellaro, Gianluca Viarengo, Cesare Perotti, Federica Meloni
Correction: Mesenchymal–epithelial transition in lymph node metastases of oral squamous cell carcinoma is accompanied by ZEB1 expression
Kai Horny, Christoph Sproll, Lukas Peiffer, Frauke Furtmann, Patricia Gerhardt, Jan Gravemeyer, Nikolas H. Stoecklein, Ivelina Spassova, Jürgen C. Becker
CLPs-miR-103a-2-5p inhibits proliferation and promotes cell apoptosis in AML cells by targeting LILRB3 and Nrf2/HO-1 axis, regulating CD8 + T cell response
Qingyan Cen, Jianyu Chen, Jiaxin Guo, Mu Chen, Hao Wang, Suwan Wu, Honghao Zhang, Xiaoling Xie, Yuhua Li
The epitome of tailor-made short positively charged peptides against HCC via integrated pharmacology
Ki-Kwang Oh, Jung-A Eom, Kyeong Jin Lee, Goo-Hyun Kwon, Sang-Jun Yoon, Seol Hee Song, Jeong Ha Park, Jeong Su Kim, Dong Joon Kim, Ki-Tae Suk
Cancer-associated fibroblast-secreted FGF7 as an ovarian cancer progression promoter
Songwei Feng, Bo Ding, Zhu Dai, Han Yin, Yue Ding, Sicong Liu, Ke Zhang, Hao Lin, Zhongdang Xiao, Yang Shen
Identification of therapeutic targets in osteoarthritis by combining heterogeneous transcriptional datasets, drug-induced expression profiles, and known drug-target interactions
Maria Claudia Costa, Claudia Angelini, Monica Franzese, Concetta Iside, Marco Salvatore, Luigi Laezza, Francesco Napolitano, Michele Ceccarelli
OralExplorer: a web server for exploring the mechanisms of oral inflammatory diseases
Weiyin Lin, Hong Yang, Jiayu Lin, Xia Yang, Zhihao Liao, Yifan Zheng, Peng Luo, Chufeng Liu
Hypoxia promotes metastasis by relieving miR-598-3p-restricted glycolysis in gastric cancer
Wei Zhou, Mengyuan Tang, Dan He, Yi Shen, Ziwei Huang, Wenxin Xia, Zhiyun Wu, Wenxiang Wei, Hui Zheng, Qi Wang, Weifeng Shi, Jingting Jiang
Predictive biomarkers for anti-TNF alpha therapy in IBD patients
Manoj Kumar, Selvasankar Murugesan, Nazira Ibrahim, Mamoun Elawad, Souhaila Al Khodor
Lactate infusion elevates cardiac output through increased heart rate and decreased vascular resistance: a randomised, blinded, crossover trial in a healthy porcine model
Oskar Kjærgaard Hørsdal, Niels Moeslund, Kristoffer Berg-Hansen, Roni Nielsen, Niels Møller, Hans Eiskjær, Henrik Wiggers, Nigopan Gopalasingam
Low-intensity pulsed ultrasound delays the progression of osteoarthritis by regulating the YAP–RIPK1–NF-κB axis and influencing autophagy
Chunran Pan, Fan Lu, Xiaoxia Hao, Xiaofeng Deng, Jiawei Liu, Kai Sun, Wenjie Hou, Xingru Shang, Ruimin Chi, Fengjing Guo, Tao Xu
Redox proteomics of PANC-1 cells reveals the significance of HIF-1 signaling protein oxidation in pancreatic ductal adenocarcinoma pathogenesis
Chaochao Tan, Lichun Chen, Xiaoyu Guan, Wenyi Huang, Yinhong Feng, Ziyi Li, Ling Wu, Xiangping Huang, Qianhui Ouyang, Sixiang Liu, Ying Huang, Jiliang Hu
Single-cell transcriptomic sequencing data reveal aberrant DNA methylation in SMAD3 promoter region in tumor-associated fibroblasts affecting molecular mechanism of radiosensitivity in non-small cell lung cancer
Fushi Han, Shuzhen Chen, Kangwei Zhang, Kunming Zhang, Meng Wang, Peijun Wang
Development and validation of predictive models for myopia onset and progression using extensive 15-year refractive data in children and adolescents
Jing Zhao, Yanze Yu, Yiming Li, Feng Li, Zhe Zhang, Weijun Jian, Zhi Chen, Yang Shen, Xiaoying Wang, Zhengqiang Ye, Chencui Huang, Xingtao Zhou
The role of DGAT1 and DGAT2 in regulating tumor cell growth and their potential clinical implications
Boer Deng, Weimin Kong, Xiaochang Shen, Chao Han, Ziyi Zhao, Shuning Chen, Chunxiao Zhou, Victoria Bae-Jump
Modulation of hippocampal protein expression by a brain penetrant biologic TNF-α inhibitor in the 3xTg Alzheimer’s disease mice
Nataraj Jagadeesan, G. Chuli Roules, Devaraj V. Chandrashekar, Joshua Yang, Sanjana Kolluru, Rachita K. Sumbria
Epigenetic MLH1 silencing concurs with mismatch repair deficiency in sporadic, naturally occurring colorectal cancer in rhesus macaques
Simon Deycmar, Brendan J. Johnson, Karina Ray, George W. Schaaf, Declan Patrick Ryan, Cassandra Cullin, Brandy L. Dozier, Betsy Ferguson, Benjamin N. Bimber, John D. Olson, David L. Caudell, Christopher T. Whitlow, Kiran Kumar Solingapuram Sai, Emily C. Romero, Francois J. Villinger, Armando G. Burgos, Hannah C. Ainsworth, Lance D. Miller, Gregory A. Hawkins, Jeff W. Chou, Bruno Gomes, Michael Hettich, Maurizio Ceppi, Jehad Charo, J. Mark Cline
Potential anti-tumor effects of regulatory T cells in the tumor microenvironment: a review
Yu Li, Cangang Zhang, Aimin Jiang, Anqi Lin, Zaoqu Liu, Xiangshu Cheng, Wanting Wang, Quan Cheng, Jian Zhang, Ting Wei, Peng Luo
Underrated aspects of a true Mediterranean diet: understanding traditional features for worldwide application of a “Planeterranean” diet
Justyna Godos, Francesca Scazzina, Corrado Paternò Castello, Francesca Giampieri, José L. Quiles, Mercedes Briones Urbano, Maurizio Battino, Fabio Galvano, Licia Iacoviello, Giovanni de Gaetano, Marialaura Bonaccio, Giuseppe Grosso
AURKB promotes bladder cancer progression by deregulating the p53 DNA damage response pathway via MAD2L2
Linzhi Li, Pengcheng Jiang, Weimin Hu, Fan Zou, Ming Li, Ting Rao, Yuan Ruan, Weimin Yu, Jinzhuo Ning, Fan Cheng
Correction: Detecting the percent of peripheral blood mononuclear cells displaying p-STAT-3 in malignant glioma patients
William Humphries, Yongtao Wang, Wei Qiao, Chantal Reina-Ortiz, Mohamed K. Abou-Ghazal, Lamonne M. Crutcher, Jun Wei, Ling-Yuan Kong, Raymond Sawaya, Ganesh Rao, Jeffrey Weinberg, Sujit S. Prabhu, Gregory N. Fuller, Amy B. Heimberger
HTRA1-driven detachment of type I collagen from endoplasmic reticulum contributes to myocardial fibrosis in dilated cardiomyopathy
Hongjie Shi, Ming Yuan, Jie Cai, Lan Lan, Yumou Wang, Wei Wang, Jianliang Zhou, Bin Wang, Wenjun Yu, Zhe Dong, Dawei Deng, Qiaofeng Qian, Yang Li, Xianwu Zhou, Jinping Liu
Statins as a risk factor for diabetic retinopathy: a Mendelian randomization and cross-sectional observational study
Chengming Chen, Huan Zhang, Yanyan Lan, Weiming Yan, Sida Liu, Yixuan Chen, Tingke Xie, Jiayi Ning, Xiaolong Yan, Lei Shang, Jing Han
Acylcarnitines promote gallbladder cancer metastasis through lncBCL2L11-THOC5-JNK axis
Yang Yang, Huaifeng Li, Ke Liu, Lu Zou, Shanshan Xiang, Yajun Geng, Xuechuan Li, Shimei Qiu, Jiahua Yang, Xuya Cui, Lin li, Yang Li, Weijian Li, Siyuan Yan, Liguo Liu, Xiangsong Wu, Fatao Liu, Wenguang Wu, Shili Chen, Yingbin Liu
Immunological profile of lactylation-related genes in Crohn’s disease: a comprehensive analysis based on bulk and single-cell RNA sequencing data
Jingtong Wu, Yinyin Lv, Pei Hao, Ziyi Zhang, Yongtian Zheng, Ermei Chen, Yanyun Fan
An integrated metabo-lipidomics profile of induced sputum for the identification of novel biomarkers in the differential diagnosis of asthma and COPD
Serena Correnti, Mariaimmacolata Preianò, Fabia Gamboni, Daniel Stephenson, Corrado Pelaia, Girolamo Pelaia, Rocco Savino, Angelo D’Alessandro, Rosa Terracciano
Integrative multi-omics analysis identifies genetically supported druggable targets and immune cell specificity for myasthenia gravis
Jiao Li, Fei Wang, Zhen Li, Jingjing Feng, Yi Men, Jinming Han, Jiangwei Xia, Chen Zhang, Yilai Han, Teng Chen, Yinan Zhao, Sirui Zhou, Yuwei Da, Guoliang Chai, Junwei Hao
Correction: Enhanced molecular release from elderly bone samples using collagenase I: insights into fatty acid metabolism alterations
Amir Mohammad Malvandi, Esra Halilaj, Martina Faraldi, Laura Mangiavini, Simone Cristoni, Valerio Leoni, Giovanni Lombardi
Caffeic acid phenethyl ester inhibits neuro-inflammation and oxidative stress following spinal cord injury by mitigating mitochondrial dysfunction via the SIRT1/PGC1α/DRP1 signaling pathway
Yanan Zhang, Qian Deng, Hongxiang Hong, Zhanyang Qian, Bowen Wan, Mingjie Xia
Extracorporeal photopheresis reduces inflammation and joint damage in a rheumatoid arthritis murine model
Yuwei Lin, Zhanrui Cheng, Yan Zhong, Yinting Zhao, Guifen Xiang, Ling Li, Li Tian, Zhong Liu
Single-cell RNA sequencing reveals recruitment of the M2-like CCL8high macrophages in Lewis lung carcinoma-bearing mice following hypofractionated radiotherapy
Haonan Yang, Zheng Lei, Jiang He, Lu Zhang, Tangmin Lai, Liu Zhou, Nuohan Wang, Zheng Tang, Jiangdong Sui, Yongzhong Wu
Transcriptome and open chromatin analysis reveals the process of myocardial cell development and key pathogenic target proteins in Long QT syndrome type 7
Peipei Chen, Junyu Long, Tianrui Hua, Zhifa Zheng, Ying Xiao, Lianfeng Chen, Kang Yu, Wei Wu, Shuyang Zhang
Protective effect of synbiotic combination of Lactobacillus plantarum SC-5 and olive oil extract tyrosol in a murine model of ulcerative colitis
Fazheng Yu, Xueyu Hu, HongLin Ren, Xiaoxu Wang, Ruoran Shi, Jian Guo, Jiang Chang, Xiaoshi Zhou, Yuanyuan Jin, Yansong Li, Zengshan Liu, Pan Hu
Dihydromyricetin ameliorates hepatic steatosis and insulin resistance via AMPK/PGC-1α and PPARα-mediated autophagy pathway
Yan Yang, Wen Qiu, Jiyuan Xiao, Jie Sun, Xuan Ren, Luxia Jiang
Exosomes from senescent epithelial cells activate pulmonary fibroblasts via the miR-217-5p/Sirt1 axis in paraquat-induced pulmonary fibrosis
Min Zhang, Xiang Xue, Zhenshuai Lou, Yanhong Lin, Qian Li, Changbao Huang
Identifying flaws in the GWAS datasets of a published Mendelian randomization study: complementary re-evaluation and suggestion for analytical refinements
Jia-Cheng Xiang, Yi-Fan Xiong, Shao-Gang Wang, Qi-Dong Xia
Bulk RNA sequencing for analysis of post COVID-19 condition in adolescents and young adults
Silke Lauren Sommen, Zhi Zhao, Sunniva Segtnan, Tonje Stiansen-Sonerud, Joel Selvakumar, Lise Beier Havdal, Johannes Gjerstad, Vegard Bruun Bratholm Wyller, Lise Lund Berven
Recent advances in endothelial colony-forming cells: from the transcriptomic perspective
Yaqiong Liu, Caomhán J. Lyons, Christine Ayu, Timothy O’Brien
Identification of novel protein biomarkers from the blood and urine for the early diagnosis of bladder cancer via proximity extension analysis
Tong Kong, Yang Qu, Taowa Zhao, Zitong Niu, Xiuyi Lv, Yiting Wang, Qiaojiao Ding, Pengyao Wei, Jun Fu, Liang Wang, Jing Gao, Cheng Zhou, Suying Wang, Junhui Jiang, Jianping Zheng, Kaizhe Wang, Kerong Wu
Characterizing and forecasting neoantigens-resulting from MUC mutations in COAD
Min Chen, Xin Zhang, Zihe Ming, Lingyu, Xiaorong Feng, Zhenguo Han, Han-Xiang An
Propofol improves survival in a murine model of sepsis via inhibiting Rab5a-mediated intracellular trafficking of TLR4
Bo-Wei Zhou, Wen-Juan Zhang, Fang-Ling Zhang, Xiao Yang, Yu-Qi Ding, Zhi-Wen Yao, Zheng-Zheng Yan, Bing-Cheng Zhao, Xiao-Dong Chen, Cai Li, Ke-Xuan Liu
Getting more bang for their buck: BCL2 inhibitors boost dendritic-cell function to enhance anti-cancer immune surveillance
Alfredo E. Montes-Gómez, Stephen W. G. Tait
Enhanced predictive validity of integrative models for refractory hyperthyroidism considering baseline and early therapy characteristics: a prospective cohort study
Xinpan Wang, Tiantian Li, Yue Li, Qiuyi Wang, Yun Cai, Zhixiao Wang, Yun Shi, Tao Yang, Xuqin Zheng
Language and cultural bias in AI: comparing the performance of large language models developed in different countries on Traditional Chinese Medicine highlights the need for localized models
Lingxuan Zhu, Weiming Mou, Yancheng Lai, Junda Lin, Peng Luo
Focused ultrasound-mediated blood–brain barrier opening is safe and feasible with moderately hypofractionated radiotherapy for brainstem diffuse midline glioma
Masih Tazhibi, Nicholas McQuillan, Hong-Jian Wei, Matthew Gallitto, Ethan Bendau, Andrea Webster Carrion, Xander Berg, Danae Kokossis, Xu Zhang, Zhiguo Zhang, Chia-Ing Jan, Akiva Mintz, Robyn D. Gartrell, Hasan R. Syed, Adriana Fonseca, Jovana Pavisic, Luca Szalontay, Elisa E. Konofagou, Stergios Zacharoulis, Cheng-Chia Wu
An integrated framework for prognosis prediction and drug response modeling in colorectal liver metastasis drug discovery
Xiuman Zhou, Yuzhen Qian, Chen Ling, Zhuoying He, Peishang Shi, Yanfeng Gao, Xinghua Sui
Very low-calorie ketogenic diet (VLCKD): a therapeutic nutritional tool for acne?
Ludovica Verde, Evelyn Frias-Toral, Sara Cacciapuoti, Daniel Simancas-Racines, Matteo Megna, Giuseppina Caiazzo, Luca Potestio, Maria Maisto, Gian Carlo Tenore, Annamaria Colao, Silvia Savastano, Giovanna Muscogiuri, Luigi Barrea
MicroRNA-21a-5p inhibition alleviates systemic sclerosis by targeting STAT3 signaling
Jin-Sil Park, Chongtae Kim, JeongWon Choi, Ha Yeon Jeong, Young-Mee Moon, Hoin Kang, Eun Kyung Lee, Mi-La Cho, Sung-Hwan Park
Complement networks in gene-edited pig xenotransplantation: enhancing transplant success and addressing organ shortage
Yinglin Yuan, Yuanyuan Cui, Dayue Zhao, Yuan Yuan, Yanshuang Zhao, Danni Li, Xiaomei Jiang, Gaoping Zhao
A redeemed strategy for molecular autopsy in unexplained infant deaths
Yuqi Yang, Haixin Li, Jingyu Zhao, Hui Huang, Bin Yu
Correlation of distribution characteristics and dynamic changes of gut microbiota with the efficacy of immunotherapy in EGFR-mutated non-small cell lung cancer
Wei-Chi Luo, Shi-Qi Mei, Zi-Jian Huang, Zhi-Hong Chen, Yi-Chen Zhang, Ming-Yi Yang, Jia-Qi Liu, Jing-Yan Xu, Xiao-Rong Yang, Ri-Wei Zhong, Li-Bo Tang, Lin-Xi Yin, Yu Deng, Ying-Long Peng, Chang Lu, Bao-Long Chen, Dong-Xian Ke, Hai-Yan Tu, Jin-Ji Yang, Chong-Rui Xu, Yi-Long Wu, Qing Zhou
Regulatory role of PI16 in autoimmune arthritis and intestinal inflammation: implications for Treg cell differentiation and function
Yuankai Sun, Shiyu Lin, Hui Wang, Lei Wang, Yulu Qiu, Feifei Zhang, Nannan Hao, Fang Wang, Wenfeng Tan
Double-negative T cells ameliorate psoriasis by selectively inhibiting IL-17A-producing γδlow T cells
Yunxiong Wei, Guangyong Sun, Yang Yang, Mingyang Li, Shimeng Zheng, Xiyu Wang, Xinjie Zhong, Zihan Zhang, Xiaotong Han, Haiyan Cheng, Dong Zhang, Xueling Mei
CD137+ and regulatory T cells as independent prognostic factors of survival in advanced non-oncogene addicted NSCLC patients treated with immunotherapy as first-line
Alain Gelibter, Angela Asquino, Lidia Strigari, Ilaria Grazia Zizzari, Lucrezia Tuosto, Fabio Scirocchi, Angelica Pace, Marco Siringo, Elisa Tramontano, Serena Bianchini, Filippo Bellati, Andrea Botticelli, Donatella Paoli, Daniele Santini, Marianna Nuti, Aurelia Rughetti, Chiara Napoletano
Systematic proteome-wide Mendelian randomization using the human plasma proteome to identify therapeutic targets for lung adenocarcinoma
Long Zhang, Yajun Xiong, Jie Zhang, Yuying Feng, Aiguo Xu
Development and validation of a model and nomogram for breast cancer diagnosis based on quantitative analysis of serum disease-specific haptoglobin N-glycosylation
Linrong Li, Yali Xu, Zhizhen Lai, Dan Li, Qiang Sun, Zhili Li, Yidong Zhou
Intestinal Piezo1 aggravates intestinal barrier dysfunction during sepsis by mediating Ca2+ influx
Zimeng Yan, Lei Niu, Shangyuan Wang, Chengjin Gao, Shuming Pan
Edge-based relative entropy as a sensitive indicator of critical transitions in biological systems
Renhao Hong, Yuyan Tong, Huisheng Liu, Pei Chen, Rui Liu
Publisher Correction to: An integrated metabo‑lipidomics profile of induced sputum for the identification of novel biomarkers in the differential diagnosis of asthma and COPD
Serena Correnti, Mariaimmacolata Preianò, Fabia Gamboni, Daniel Stephenson, Corrado Pelaia, Girolamo Pelaia, Rocco Savino, Angelo D’Alessandro, Rosa Terracciano
CDC45 promotes the stemness and metastasis in lung adenocarcinoma by affecting the cell cycle
Yafeng Liu, Tao Han, Zhi Xu, Jing Wu, Jiawei Zhou, Jianqiang Guo, Rui Miao, Yingru Xing, Deyong Ge, Ying Bai, Dong Hu
Melanocytes in regenerative medicine applications and disease modeling
Kelly Coutant, Brice Magne, Karel Ferland, Aurélie Fuentes-Rodriguez, Olivier Chancy, Andrew Mitchell, Lucie Germain, Solange Landreville
Wnt, glucocorticoid and cellular prion protein cooperate to drive a mesenchymal phenotype with poor prognosis in colon cancer
Sophie Mouillet-Richard, Angélique Gougelet, Bruno Passet, Camille Brochard, Delphine Le Corre, Caterina Luana Pitasi, Camille Joubel, Marine Sroussi, Claire Gallois, Julien Lavergne, Johan Castille, Marthe Vilotte, Nathalie Daniel-Carlier, Camilla Pilati, Aurélien de Reyniès, Fatima Djouadi, Sabine Colnot, Thierry André, Julien Taieb, Jean-Luc Vilotte, Béatrice Romagnolo, Pierre Laurent-Puig
SIRPB1 regulates inflammatory factor expression in the glioma microenvironment via SYK: functional and bioinformatics insights
Ren Geng, Yao Zhao, Wanzhen Xu, Xiaoshan Ma, Yining Jiang, Xuefei Han, Liyan Zhao, Yunqian Li
Liposomes, transfersomes and niosomes: production methods and their applications in the vaccinal field
Domenico Riccardi, Lucia Baldino, Ernesto Reverchon
Overexpression of TNFSF11 reduces GPX4 levels and increases sensitivity to ferroptosis inducers in lung adenocarcinoma
Zizhen Li, Wenhua Lu, Feng Yin, Peiting Zeng, Heping Li, Amin Huang
In situ chemoimmunotherapy hydrogel elicits immunogenic cell death and evokes efficient antitumor immune response
Qin Liu, Rui Xu, Jingwen Shen, Yaping Tao, Jingyi Shao, Yaohua Ke, Baorui Liu
Longitudinal study of the impact of the COVID-19 pandemic on diet and physical activity among Latinos of Mexican ancestry
Giovanna Muscogiuri, Lindsay Kohler, Oscar Parra, Lisa Soltani, Douglas Spegman, Dawn Coletta, Lawrence J. Mandarino
Association of circulating biomarkers with illness severity measures differentiates myalgic encephalomyelitis/chronic fatigue syndrome and post-COVID-19 condition: a prospective pilot cohort study
Joan Carles Domingo, Federica Battistini, Begoña Cordobilla, Maria Cleofé Zaragozá, Ramón Sanmartin-Sentañes, Jose Alegre-Martin, Trinitat Cambras, Jesus Castro-Marrero
Lack of shared neoantigens in prevalent mutations in cancer
Concetta Ragone, Beatrice Cavalluzzo, Angela Mauriello, Maria Tagliamonte, Luigi Buonaguro
Increased risk of psychiatric disorder in patients with hearing loss: a nationwide population-based cohort study
Qun-Yi Nian, Chun-An Cheng, Li-Hsiang Cheng, Yuan-Yung Lin, Chin-Hung Wang, Wu-Chien Chien, Yueng-Hsiang Chu, Cheng-Ping Shih, Chao-Yin Kuo, Hsin-Chien Chen, Jih-Chin Lee, Chi-Hsiang Chung, Wei-Chuan Shangkuan, Hung-Che Lin
The integration of single-cell and bulk RNA-seq atlas reveals ERS-mediated acinar cell damage in acute pancreatitis
Kaige Yang, Rongli Xie, Guohui Xiao, Zhifeng Zhao, Min Ding, Tingyu Lin, Yiu Sing Tsang, Ying Chen, Dan Xu, Jian Fei
THOC7-AS1/OCT1/FSTL1 axis promotes EMT and serves as a therapeutic target in cutaneous squamous cell carcinoma
Site Yu, Xu Cui, Situo Zhou, Yun Li, Wenjie Feng, Xiangjun Zhang, Yuhui Zhong, Pihong Zhang
Immersed in a reservoir of potential: amniotic fluid-derived extracellular vesicles
Ishara Atukorala, Natalie Hannan, Lisa Hui
Development of nanobodies targeting hepatocellular carcinoma and application of nanobody-based CAR-T technology
Keming Lin, Baijin Xia, Xuemei Wang, Xin He, Mo Zhou, Yingtong Lin, Yidan Qiao, Rong Li, Qier Chen, Yuzhuang Li, Jinzhu Feng, Tao Chen, Cancan Chen, Xinyu Li, Hui Zhang, Lijuan Lu, Bingfeng Liu, Xu Zhang
Nicotine restores olfactory function by activation of prok2R/Akt/FoxO3a axis in Parkinson’s disease
Qinglong Guo, Yi Wang, Liangchen Yu, Liao Guan, Xuefei Ji, Xiaohui Li, Gang Pang, Zhenhua Ren, Lei Ye, Hongwei Cheng
Stromal cartilage oligomeric matrix protein as a tumorigenic driver in ovarian cancer via Notch3 signaling and epithelial-to-mesenchymal transition
Gilar Gorji-Bahri, B. Madhu Krishna, Catharina Hagerling, Akira Orimo, Karin Jirström, Konstantinos S. Papadakos, Anna M. Blom
Quinic acid regulated TMA/TMAO-related lipid metabolism and vascular endothelial function through gut microbiota to inhibit atherosclerotic
Qiao Jin, Chiyuan Zhang, Ran Chen, Luping Jiang, Hongli Li, Pengcui Wu, Liang Li
Architecting the metabolic reprogramming survival risk framework in LUAD through single-cell landscape analysis: three-stage ensemble learning with genetic algorithm optimization
Xinti Sun, Minyu Nong, Fei Meng, Xiaojuan Sun, Lihe Jiang, Zihao Li, Peng Zhang
Application of high-precision 3D scanner in keloids evaluation to improve patients’ compliance: a questionnaire-based study
Huayi Wu, Zixi Jiang, Xiang Chen, Shuang Zhao, Zeyu Chen
Polygenic risk score-based phenome-wide association for glaucoma and its impact on disease susceptibility in two large biobanks
Jae-Seung Yun, Sang-Hyuk Jung, Su-Nam Lee, Seung Min Jung, Daniel J. Rader, Marylyn D. Ritchie, JoEllen Weaver, Nawar Naseer, Giorgio Sirugo, Afiya Poindexter, Yi-An Ko, Kyle P. Nerz, Meghan Livingstone, Fred Vadivieso, Stephanie DerOhannessian, Teo Tran, Julia Stephanowski, Salma Santos, Ned Haubein, Joseph Dunn, Anurag Verma, Colleen Morse Kripke, Marjorie Risman, Renae Judy, Colin Wollack, Anurag Verma, Shefali S. Verma, Scott Damrauer, Yuki Bradford, Scott Dudek, Theodore Drivas, Hong-Hee Won, Dokyoon Kim, Jin A. Choi
Enhancing prediction accuracy of coronary artery disease through machine learning-driven genomic variant selection
Z. Alireza, M. Maleeha, M. Kaikkonen, V. Fortino
Desmosomes in heart and skin: friends or foes?
Giuseppina Caiazzo, Rosa Redenta De Simone, Emanuele Monda, Ferdinando Barretta, Fabiana Uomo, Cristina Mazzaccara, Matteo Megna, Limongelli Giuseppe, Giulia Frisso
Machine learning and optical coherence tomography-derived radiomics analysis to predict persistent diabetic macular edema in patients undergoing anti-VEGF intravitreal therapy
Zhishang Meng, Yanzhu Chen, Haoyu Li, Yue Zhang, Xiaoxi Yao, Yongan Meng, Wen Shi, Youling Liang, Yuqian Hu, Dan Liu, Manyun Xie, Bin Yan, Jing Luo
Single-cell transcriptomics dissects the transcriptome alterations of hematopoietic stem cells in myelodysplastic neoplasms
Xiangzong Zeng, Yichen Wang, Min Dai, Wei Li, Qingtian Huang, Lingsha Qin, Yuquan Li, Yanwen Yan, Xiangjun Xue, Fang Yi, Wenhao Li, Langyu He, Qifa Liu, Ling Qi
Landscapes of gut bacterial and fecal metabolic signatures and their relationship in severe preeclampsia
Xianxian Liu, Xiaoming Zeng, Xing Li, Siming Xin, Feng Zhang, Faying Liu, Yang Zeng, Jilin Wu, Yang Zou, Xinwei Xiong
Prevalence of diverse colorectal polyps and risk factors for colorectal carcinoma in situ and neoplastic polyps
Xiaojuan Li, Mengting Hu, Zhangjun Wang, Mei Liu, Ying Chen
DB-1310, an ADC comprised of a novel anti-HER3 antibody conjugated to a DNA topoisomerase I inhibitor, is highly effective for the treatment of HER3-positive solid tumors
Xi Li, Jun Yao, Chen Qu, Lan Luo, Bing Li, Yu Zhang, Zhongyuan Zhu, Yang Qiu, Haiqing Hua
IL-33 regulates adipogenesis via Wnt/β-catenin/PPAR-γ signaling pathway in preadipocytes
Danning Xu, Siqi Zhuang, Hongzhi Chen, Mengjie Jiang, Ping Jiang, Qian Wang, Xuemei Wang, Ruohong Chen, Haoneng Tang, Lingli Tang
Integrated lipid metabolomics and proteomics analysis reveal the pathogenesis of polycystic ovary syndrome
Yu Qian, Yun Tong, Yaqiong Zeng, Jingyu Huang, Kailu Liu, Ying Xie, Juan Chen, Mengya Gao, Li Liu, Juan Zhao, Yanli Hong, Xiaowei Nie
Tumor immune dysfunction and exclusion subtypes in bladder cancer and pan-cancer: a novel molecular subtyping strategy and immunotherapeutic prediction model
Kun Zheng, Youlong Hai, Hongqi Chen, Yukun Zhang, Xiaoyong Hu, Kai Ni
An early-onset specific polygenic risk score optimizes age-based risk estimate and stratification of prostate cancer: population-based cohort study
Yifei Cheng, Lang Wu, Junyi Xin, Shuai Ben, Silu Chen, Huiqin Li, Lingyan Zhao, Meilin Wang, Gong Cheng, Mulong Du
Mesothelin-based CAR-T cells exhibit potent antitumor activity against ovarian cancer
Jing Guo, Xiaozhu Zeng, Yongjie Zhu, Dong Yang, Xudong Zhao
The development of chimeric antigen receptor T-cells against CD70 for renal cell carcinoma treatment
Qinghui Xiong, Haiying Wang, Qiushuang Shen, Yan Wang, Xiujie Yuan, Guangyao Lin, Pengfei Jiang
Short-chain fatty acid-producing bacterial strains attenuate experimental ulcerative colitis by promoting M2 macrophage polarization via JAK/STAT3/FOXO3 axis inactivation
Hailan Zhao, Youlian Zhou, Jing Xu, Yong Zhang, Hong Wang, Chong Zhao, Hongli Huang, Jing Yang, Chen Huang, Yingfei Li, Lisheng Wang, Yuqiang Nie
Discovery of a novel and highly selective JAK3 inhibitor as a potent hair growth promoter
Md Mehedi Hossain, Arfan Khalid, Zaheen Akhter, Sabra Parveen, Mir Owais Ayaz, Aadil Qadir Bhat, Neetu Badesra, Farheen Showket, Mohmmad Saleem Dar, Farhan Ahmed, Sumit Dhiman, Mukesh Kumar, Umed Singh, Razak Hussain, Pankaj Keshari, Ghulam Mustafa, Amit Nargorta, Neha Taneja, Somesh Gupta, Riyaz A. Mir, Aravind Singh Kshatri, Utpal Nandi, Nooruddin Khan, P. Ramajayan, Govind Yadav, Zabeer Ahmed, Parvinder Pal Singh, Mohd Jamal Dar
The interaction of platelet-related factors with tumor cells promotes tumor metastasis
Jie Xue, Jianzhao Deng, Hongwei Qin, Songxia Yan, Zhen Zhao, Lifeng Qin, Jiao Liu, Haiyan Wang
Implications of ZNF334 gene in lymph node metastasis of lung SCC: potential bypassing of cellular senescence
Khalil Khashei Varnamkhasti, Mehdi Moghanibashi, Sirous Naeimi
Dissecting the shared genetic landscape of anxiety, depression, and schizophrenia
Yiming Tao, Rui Zhao, Bin Yang, Jie Han, Yongsheng Li
Mutational landscape of inflammatory breast cancer
François Bertucci, Florence Lerebours, Michele Ceccarelli, Arnaud Guille, Najeeb Syed, Pascal Finetti, José Adélaïde, Steven Van Laere, Anthony Goncalves, Patrice Viens, Daniel Birnbaum, Emilie Mamessier, Céline Callens, Davide Bedognetti
The redox-active defensive Selenoprotein T as a novel stress sensor protein playing a key role in the pathophysiology of heart failure
Anna De Bartolo, Teresa Pasqua, Naomi Romeo, Vittoria Rago, Ida Perrotta, Francesca Giordano, Maria Concetta Granieri, Alessandro Marrone, Rosa Mazza, Maria Carmela Cerra, Benjamin Lefranc, Jérôme Leprince, Youssef Anouar, Tommaso Angelone, Carmine Rocca
Correction to: COSMIC‑based mutation database enhances identification efficiency of HLA‑I immunopeptidome
Fangzhou Wang, Zhenpeng Zhang, Mingsong Mao, Yudai Yang, Ping Xu, Shichun Lu
Assessment of cephalometric parameters and correlation with the severity of the obstructive sleep apnea syndrome
Eugenio Garofalo, Giuseppe Neri, Lucilla Maria Perri, Nicola Lombardo, Giovanna Piazzetta, Alessandro Antonelli, Eugenio Biamonte, Vincenzo Bosco, Caterina Battaglia, Corrado Pelaia, Francesco Manti, Annalisa Pitino, Giovanni Tripepi, Andrea Bruni, Michele Morelli, Amerigo Giudice, Federico Longhini, Selene Barone, Antonio Caroleo, Angela Corea, Giusy Guzzi, Lucia Lentini, Sebastiano Macheda, Pietro Maglio, Helenia Mastrangelo, Alessandra Pasqua, Marianna Salviati, Marco Tescione
Arginine-linked HPV-associated E7 displaying bacteria-derived outer membrane vesicles as a potent antigen-specific cancer vaccine
Suyang Wang, Chao-Cheng Chen, Ming-Hung Hu, Michelle Cheng, Hsin-Fang Tu, Ya-Chea Tsai, Jr-Ming Yang, T. C. Wu, Chuan-Hsiang Huang, Chien-Fu Hung
Predictive significance of FGFR4 p.G388R polymorphism in metastatic colorectal cancer patients receiving trifluridine/tipiracil (TAS-102) treatment
Alessandro Ottaiano, Mariachiara Santorsola, Monica Ianniello, Anna Ceccarelli, Marika Casillo, Francesco Sabbatino, Nadia Petrillo, Marco Cascella, Francesco Caraglia, Carmine Picone, Francesco Perri, Roberto Sirica, Silvia Zappavigna, Guglielmo Nasti, Giovanni Savarese, Michele Caraglia
Integrating spatial transcriptomics and single-cell RNA-sequencing reveals the alterations in epithelial cells during nodular formation in benign prostatic hyperplasia
Xiawei Fei, Jican Liu, Junyan Xu, Hongyan Jing, Zhonglin Cai, Jiasheng Yan, Zhenqi Wu, Huifeng Li, Zhong Wang, Yanting Shen
Integrated multi-omics analysis and machine learning developed a prognostic model based on mitochondrial function in a large multicenter cohort for Gastric Cancer
Yimeng Ma, Jingjing Jin, Zixuan Xue, Jungang Zhao, Weiyang Cai, Wanli Zhang
Understanding the matrix: collagen modifications in tumors and their implications for immunotherapy
Rowie Borst, Linde Meyaard, M. Ines Pascoal Ramos
AZGP1 deficiency promotes angiogenesis in prostate cancer
Ru M. Wen, Zhengyuan Qiu, G. Edward W. Marti, Eric E. Peterson, Fernando Jose Garcia Marques, Abel Bermudez, Yi Wei, Rosalie Nolley, Nathan Lam, Alex LaPat Polasko, Chun-Lung Chiu, Dalin Zhang, Sanghee Cho, Grigorios Marios Karageorgos, Elizabeth McDonough, Chrystal Chadwick, Fiona Ginty, Kyeong Joo Jung, Raghu Machiraju, Parag Mallick, Laura Crowley, Jonathan R. Pollack, Hongjuan Zhao, Sharon J. Pitteri, James D. Brooks
Deciphering the importance of culture pH on CD22 CAR T-cells characteristics
Michaela Prochazkova, Alexandra Dreyzin, Lipei Shao, Pam Garces, Yihua Cai, Rongye Shi, Alejandra Pelayo, Yong Soo Kim, Victoria Pham, Sue Ellen Frodigh, Shannon Fenton, Catherine Karangwa, Yan Su, Kathryn Martin, Nan Zhang, Steven L. Highfill, Robert P. Somerville, Nirali N. Shah, David F. Stroncek, Ping Jin
Retraction Note: Palmitoyl transferases act as novel drug targets for pancreatic cancer
Zhiqing Lin, Ziru Lv, Xin Liu, Keke Huang
A PCR-independent approach for mtDNA enrichment and next-generation sequencing: comprehensive evaluation and clinical application
Dong Liang, Lin Zhu, Yuqing Zhu, Mingtao Huang, Ying Lin, Hang Li, Ping Hu, Jun Zhang, Bin Shen, Zhengfeng Xu
xWAS analysis in neuropsychiatric disorders by integrating multi-molecular phenotype quantitative trait loci and GWAS summary data
Lingxue Luo, Tao Pang, Haohao Zheng, Chao Liufu, Suhua Chang
Recent advances in the discovery and development of drugs targeting the kallikrein-kinin system
Petra Wisniewski, Tanja Gangnus, Bjoern B. Burckhardt
Deciphering the role of FUS::DDIT3 expression and tumor microenvironment in myxoid liposarcoma development
Parmida Ranji, Emma Jonasson, Lisa Andersson, Stefan Filges, Manuel Luna Santamaría, Christoffer Vannas, Soheila Dolatabadi, Anna Gustafsson, Ola Myklebost, Joakim Håkansson, Henrik Fagman, Göran Landberg, Pierre Åman, Anders Ståhlberg
CAV3 alleviates diabetic cardiomyopathy via inhibiting NDUFA10-mediated mitochondrial dysfunction
Ping Guo, Shuiqing Hu, Xiaohui Liu, Miaomiao He, Jie Li, Tingqiong Ma, Man Huang, Qin Fang, Yan Wang
HIF-1α-mediated LAMC1 overexpression is an unfavorable predictor of prognosis for glioma patients: evidence from pan-cancer analysis and validation experiments
Jianrong Bai, Yangyang Zhao, Kaijia Shi, Yonghao Fan, Yanping Ha, Yan Chen, Botao Luo, Yanda Lu, Wei Jie, Zhihua Shen
Large-scale genome-wide association studies reveal the genetic causal etiology between air pollutants and autoimmune diseases
Jie Wen, Jingwei Zhang, Hao Zhang, Nan Zhang, Ruoyan Lei, Yujia Deng, Quan Cheng, He Li, Peng Luo
Comprehensive analysis of bulk and single-cell transcriptomic data reveals a novel signature associated with endoplasmic reticulum stress, lipid metabolism, and liver metastasis in pancreatic cancer
Xiaohong Liu, Bo Ren, Yuan Fang, Jie Ren, Xing Wang, Minzhi Gu, Feihan Zhou, Ruiling Xiao, Xiyuan Luo, Lei You, Yupei Zhao
CD8+ T cell-based cancer immunotherapy
Yanxia Chen, Dingning Yu, Hui Qian, Yinghong Shi, Zhimin Tao
Therapeutic efficacy of a novel self-assembled immunostimulatory siRNA combining apoptosis promotion with RIG-I activation in gliomas
Junxiao Chen, Ziyuan Liu, Haiting Fang, Qing Su, Yiqi Fan, Luyao Song, Shuai He
Relationship between vaginal and oral microbiome in patients of human papillomavirus (HPV) infection and cervical cancer
Wei Zhang, Yanfei Yin, Yisha Jiang, Yangyang Yang, Wentao Wang, Xiaoya Wang, Yan Ge, Bin Liu, Lihe Yao
Artificial intelligence assists identification and pathologic classification of glomerular lesions in patients with diabetic nephropathy
Qunjuan Lei, Xiaoshuai Hou, Xumeng Liu, Dongmei Liang, Yun Fan, Feng Xu, Shaoshan Liang, Dandan Liang, Jing Yang, Guotong Xie, Zhihong Liu, Caihong Zeng
Changes in blood metabolomes as potential markers for severity and prognosis in doxorubicin-induced cardiotoxicity: a study in HER2-positive and HER2-negative breast cancer patients
Chanisa Thonusin, Nichanan Osataphan, Krit Leemasawat, Wichwara Nawara, Sirawit Sriwichaiin, Siriporn Supakham, Siriluck Gunaparn, Nattayaporn Apaijai, Areewan Somwangprasert, Arintaya Phrommintikul, Siriporn C. Chattipakorn, Nipon Chattipakorn
Potential value of CT-based comprehensive nomogram in predicting occult lymph node metastasis of esophageal squamous cell paralaryngeal nerves: a two-center study
Ting Xue, Xinyi Wan, Taohu Zhou, Qin Zou, Chao Ma, Jieqiong Chen
Correction: Implementation of genomic medicine for rare disease in a tertiary healthcare system: Mayo Clinic Program for Rare and Undiagnosed Diseases (PRaUD)
Filippo Pinto e Vairo, Jennifer L. Kemppainen, Carolyn R. Rohrer Vitek, Denise A. Whalen, Kayla J. Kolbert, Kaitlin J. Sikkink, Sarah A. Kroc, Teresa Kruisselbrink, Gabrielle F. Shupe, Alyssa K. Knudson, Elizabeth M. Burke, Elle C. Loftus, Lorelei A. Bandel, Carri A. Prochnow, Lindsay A. Mulvihill, Brittany Thomas, Dale M. Gable, Courtney B. Graddy, Giovanna G. Moreno Garzon, Idara U. Ekpoh, Eva M. Carmona Porquera, Fernando C. Fervenza, Marie C. Hogan, Mireille El Ters, Kenneth J. Warrington, John M. Davis III, Matthew J. Koster, Amir B. Orandi, Matthew L. Basiaga, Adrian Vella, Seema Kumar, Ana L. Creo, Aida N. Lteif, Siobhan T. Pittock, Peter J. Tebben, Ejigayehu G. Abate, Avni Y. Joshi, Elizabeth H. Ristagno, Mrinal S. Patnaik, Lisa A. Schimmenti, Radhika Dhamija, Sonia M. Sabrowsky, Klaas J. Wierenga, Mira T. Keddis, Niloy Jewel J. Samadder, Richard J. Presutti, Steven I. Robinson, Michael C. Stephens, Lewis R. Roberts, William A. Faubion Jr., Sherilyn W. Driscoll, Lily C. Wong-Kisiel, Duygu Selcen, Eoin P. Flanagan, Vijay K. Ramanan, Lauren M. Jackson, Michelle L. Mauermann, Victor E. Ortega, Sarah A. Anderson, Stacy L. Aoudia, Eric W. Klee, Tammy M. McAllister, Konstantinos N. Lazaridis
Fusobacterium periodonticum BCT protein targeting glucose metabolism to promote the epithelial-mesenchymal transition of esophageal cancer cells by lactic acid
Xinxin Guo, Ping Wan, Weitao Shen, Mingjun Sun, Zhenyan Peng, Yinghao Liao, Yang Huang, Ran Liu
Targeting interleukin-6 as a treatment approach for peritoneal carcinomatosis
Neda Dadgar, Christopher Sherry, Jenna Zimmerman, Hyun Park, Catherine Lewis, Albert Donnenberg, Ali H. Zaidi, Yong Fan, Kunhong Xiao, David Bartlett, Vera Donnenberg, Patrick L. Wagner
The association of ROS1 mutation with cancer immunity and its impact on the efficacy of pan-cancer immunotherapy
Yingying Li, Hong Zhao, Jinyuan Huang, Huimeng Yan, Bin Zhao
Comprehensive mendelian randomization analysis of plasma proteomics to identify new therapeutic targets for the treatment of coronary heart disease and myocardial infarction
Ziyi Sun, Zhangjun Yun, Jianguo Lin, Xiaoning Sun, Qingqing Wang, Jinlong Duan, Cheng Li, Xiaoxiao Zhang, Siyu Xu, Zeqi Wang, Xingjiang Xiong, Kuiwu Yao
Developing and validating a clinlabomics-based machine-learning model for early detection of retinal detachment in patients with high myopia
Shengjie Li, Meiyan Li, Jianing Wu, Yingzhu Li, Jianping Han, Yunxiao Song, Wenjun Cao, Xingtao Zhou
Blockade of PI3K/AKT signaling pathway by Astragaloside IV attenuates ulcerative colitis via improving the intestinal epithelial barrier
Xinhui Zhang, Fan Zhang, Yan Li, Na Fan, Ke Zhao, Anding Zhang, Jiefang Kang, Yan Lin, Xiaochang Xue, Xun Jiang
PGRN is involved in macrophage M2 polarization regulation through TNFR2 in periodontitis
Liguo Zhang, Fujiao Nie, Jingjing Zhao, Shutong Li, Wenchuan Liu, Hongmei Guo, Pishan Yang
Exosomes in the pathogenesis and treatment of cancer-related cachexia
Qin Ru, Lin Chen, Guodong Xu, Yuxiang Wu
Type 2 diabetic mellitus related osteoporosis: focusing on ferroptosis
Yili Chen, Wen Zhao, An Hu, Shi Lin, Ping Chen, Bing Yang, Zhirong Fan, Ji Qi, Wenhui Zhang, Huanhuan Gao, Xiubing Yu, Haiyun Chen, Luyuan Chen, Haizhou Wang
Measurable residual disease monitoring by ddPCR in the early posttransplant period complements the traditional MFC method to predict relapse after HSCT in AML/MDS: a multicenter retrospective study
Weihao Chen, Jingtao Huang, Yeqian Zhao, Luo Huang, Zhiyang Yuan, Miner Gu, Xiaojun Xu, Jimin Shi, Yi Luo, Jian Yu, Xiaoyu Lai, Lizhen Liu, Huarui Fu, Chenhui Bao, Xin Huang, Zhongzheng Zheng, He Huang, Xiaoxia Hu, Yanmin Zhao
Tribulations and future opportunities for artificial intelligence in precision medicine
Claudio Carini, Attila A. Seyhan
Removal of endothelial surface-associated von villebrand factor suppresses accelerate datherosclerosis after myocardial infarction
Koya Ozawa, William Packwood, Matthew A Muller, Yue Qi, Aris Xie, Oleg Varlamov, Owen J. McCarty, Dominic Chung, José A. López, Jonathan R. Lindner
The potential and promise for clinical application of adoptive T cell therapy in cancer
Yinqi Li, Yeteng Zheng, Taiqing Liu, Chuanyun Liao, Guobo Shen, Zhiyao He
Genomic landscape and distinct molecular subtypes of primary testicular lymphoma
Weilong Zhang, Ping Yang, Yaru Yang, Shuozi Liu, Yongdeng Xu, Chaoling Wu, Jing Wang, Cuiling Liu, Hui Liu, Shuangshuang Li, Wei Huang, Hongmei Jing
Correction to: Silencing PinX1 enhances radiosensitivity and antitumor-immunity of radiotherapy in non-small cell lung cancer
Jieping Qiu, Ying Xia, Yawei Bao, Jingjing Cheng, Lei Liu, Dong Qian
Mechanism of action, potency and efficacy: considerations for cell therapies
Carl G. Simon Jr., Erich H. Bozenhardt, Christina M. Celluzzi, David Dobnik, Melanie L. Grant, Uma Lakshmipathy, Thiana Nebel, Linda Peltier, Anthony Ratcliffe, James L. Sherley, Glyn N. Stacey, Rouzbeh R. Taghizadeh, Eddie H. P. Tan, Sandrine Vessillier
Impact of fundamental components of the Mediterranean diet on the microbiota composition in blood pressure regulation
Ana Karina Zambrano, Santiago Cadena-Ullauri, Viviana A. Ruiz-Pozo, Rafael Tamayo-Trujillo, Elius Paz-Cruz, Patricia Guevara-Ramírez, Evelyn Frias-Toral, Daniel Simancas-Racines
Targeting histone deacetylases in head and neck squamous cell carcinoma: molecular mechanisms and therapeutic targets
Mengchen Xu, Yiming Hou, Na Li, Wenqian Yu, Lei Chen
VEGFR2 blockade inhibits glioblastoma cell proliferation by enhancing mitochondrial biogenesis
Min Guo, Junhao Zhang, Jiang Han, Yingyue Hu, Hao Ni, Juan Yuan, Yang Sun, Meijuan Liu, Lifen Gao, Wangjun Liao, Chunhong Ma, Yaou Liu, Shuijie Li, Nailin Li
Correction to: Role of Hippo pathway dysregulation from gastrointestinal premalignant lesions to cancer
Giulia Schiavoni, Beatrice Messina, Stefano Scalera, Lorenzo Memeo, Cristina Colarossi, Marzia Mare, Giovanni Blandino, Gennaro Ciliberto, Giulia Bon, Marcello Maugeri-Saccà
Immune checkpoint inhibitors induce acute interstitial nephritis in mice with increased urinary MCP1 and PD-1 glomerular expression
Laura Martinez Valenzuela, Francisco Gómez-Preciado, Jordi Guiteras, Paula Antón Pampols, Montserrat Gomà, Xavier Fulladosa, Josep Maria Cruzado, Joan Torras, Juliana Draibe
Integrative analyses of bulk and single-cell transcriptomics reveals the infiltration and crosstalk of cancer-associated fibroblasts as a novel predictor for prognosis and microenvironment remodeling in intrahepatic cholangiocarcinoma
Yan-Jie Zhong, Xi-Mei Luo, Fei Liu, Zhi-Qiang He, Si-Qi Yang, Wen-Jie Ma, Jun-Ke Wang, Yu-Shi Dai, Rui-Qi Zou, Ya-Fei Hu, Tian-Run Lv, Fu-Yu Li, Hai-Jie Hu
Comprehensive characterization of stemness-related lncRNAs in triple-negative breast cancer identified a novel prognostic signature related to treatment outcomes, immune landscape analysis and therapeutic guidance: a silico analysis with in vivo experiments
Min Zhang, Fangxu Zhang, Jianfeng Wang, Qian Liang, Weibing Zhou, Jian Liu
Differences of skin carotenoids and adherence to the Mediterranean Diet pattern in adults from Southern Italy and Dominican Republic
Giuseppina Augimeri, Manuel Soto, Fabrizio Ceraudo, Giovanna Caparello, Melisa Villegas Figueroa, Mirko Cesario, Lorenzo S. Caputi, Berniza Calderón, Daniela Bonofiglio
Genetic association and causal relationship between multiple modifiable risk factors and autoimmune liver disease: a two-sample mendelian randomization study
Weize Gao, Chong Peng, Zhan Wang, Yongxin Li, Mingjun Liu
Engineering PD-1-targeted small protein variants for in vitro diagnostics and in vivo PET imaging
Joanna Maria Mierzwicka, Hana Petroková, Leona Rašková Kafková, Petr Kosztyu, Jiří Černý, Milan Kuchař, Miloš Petřík, Kateřina Bendová, Kristýna Krasulová, Yaroslava Groza, Lucie Vaňková, Shiv Bharadwaj, Natalya Panova, Michal Křupka, Jozef Škarda, Milan Raška, Petr Malý
Exosome-transported circ_0061407 and circ_0008103 play a tumour-repressive role and show diagnostic value in non-small-cell lung cancer
Zhenhua Chen, Xinyi Ma, Ziyuan Chen, Wei Chen, Leyi Li, Yichen Lin, Yulin Hu, Yue Shang, Yikai Zhao, Jinxian He, Chengwei Zhou, Xiaodan Meng
Novel genome-wide DNA methylation profiling reveals distinct epigenetic landscape, prognostic model and cellular composition of early-stage lung adenocarcinoma
Junwen Gan, Meng Huang, Weishi Wang, Guining Fu, Mingyuan Hu, Hongcheng Zhong, Xin Ye, Qingdong Cao
Chronic atrophic gastritis and risk of incident upper gastrointestinal cancers: a systematic review and meta-analysis
Junqiu Li, Jielu Pan, Dinghong Xiao, Nan Shen, Ruiqing Wang, Hongyv Miao, Peimin Pu, Haiyan Zhang, Xiao Yv, Lianjun Xing
Passive immunotherapy for Alzheimer’s disease: challenges & future directions
Ling Xiao Yi, Eng King Tan, Zhi Dong Zhou
Multiomics analysis identifies oxidative phosphorylation as a cancer vulnerability arising from myristoylation inhibition
Erwan Beauchamp, Jay M. Gamma, Christopher R. Cromwell, Eman W. Moussa, Rony Pain, Morris A. Kostiuk, Claudia Acevedo-Morantes, Aishwarya Iyer, Megan Yap, Krista M. Vincent, Lynne M. Postovit, Olivier Julien, Basil P. Hubbard, John R. Mackey, Luc G. Berthiaume
Predicting humoral responses to primary and booster SARS-CoV-2 mRNA vaccination in people living with HIV: a machine learning approach
Giorgio Montesi, Matteo Augello, Jacopo Polvere, Giulia Marchetti, Donata Medaglini, Annalisa Ciabattini
Role of gut microbiota in doxorubicin-induced cardiotoxicity: from pathogenesis to related interventions
Chao Huang, Xiaoxia Li, Hanqing Li, Ruolan Chen, Zhaoqing Li, Daisong Li, Xiaojian Xu, Guoliang Zhang, Luning Qin, Bing Li, Xian-Ming Chu
Deep learning imaging phenotype can classify metabolic syndrome and is predictive of cardiometabolic disorders
Jacob S. Leiby, Matthew E. Lee, Manu Shivakumar, Eun Kyung Choe, Dokyoon Kim
Advances and challenges of the cell-based therapies among diabetic patients
Ramin Raoufinia, Hamid Reza Rahimi, Ehsan Saburi, Meysam Moghbeli
FGF21 attenuates neuroinflammation following subarachnoid hemorrhage through promoting mitophagy and inhibiting the cGAS-STING pathway
Yue Ma, Zhiqin Liu, Lele Deng, Jingjing Du, Zenghui Fan, Tian Ma, Jing Xiong, Xue Xiuyun, Naibing Gu, Zhengli Di, Yu Zhang
Fluorinated hydroxyapatite conditions a favorable osteo-immune microenvironment via triggering metabolic shift from glycolysis to oxidative phosphorylation
Kaidi Chen, Seongmin Ha, Leyao Xu, Chengwu Liu, Yuanxiang Liu, Xiayi Wu, Zhipeng Li, Shiyu Wu, Bo Yang, Zhuofan Chen
Deep learning based digital pathology for predicting treatment response to first-line PD-1 blockade in advanced gastric cancer
Yifan Liu, Wei Chen, Ruiwen Ruan, Zhimei Zhang, Zhixiong Wang, Tianpei Guan, Qi Lin, Wei Tang, Jun Deng, Zhao Wang, Guanghua Li
IL-2RG as a possible immunotherapeutic target in CRC predicting poor prognosis and regulated by miR-7-5p and miR-26b-5p
Ehsan Gharib, Leili Rejali, Moein Piroozkhah, Elham Zonoobi, Parinaz Nasri Nasrabadi, Zahra Arabsorkhi, Kaveh Baghdar, Elahe Shams, Amir Sadeghi, Peter J. K. Kuppen, Zahra Salehi, Ehsan Nazemalhosseini-Mojarad
MiR-146a reduces fibrosis after glaucoma filtration surgery in rats
Ruiqi Han, Huimin Zhong, Yang Zhang, Huan Yu, Yumeng Zhang, Shouyue Huang, Zijian Yang, Yisheng Zhong
The microtubule targeting agent ST-401 triggers cell death in interphase and prevents the formation of polyploid giant cancer cells
Juan Jesus Vicente, Kainat Khan, Grant Tillinghast, José L. McFaline-Figueroa, Yasemin Sancak, Nephi Stella
Choline metabolism reprogramming mediates an immunosuppressive microenvironment in non-small cell lung cancer (NSCLC) by promoting tumor-associated macrophage functional polarization and endothelial cell proliferation
Bijing Xiao, Guanjun Li, Haimiti Gulizeba, Hong Liu, Xiaoxian Sima, Ting Zhou, Yan Huang
Keratin 17 modulates the immune topography of pancreatic cancer
Lyanne Delgado-Coka, Michael Horowitz, Mariana Torrente-Goncalves, Lucia Roa-Peña, Cindy V. Leiton, Mahmudul Hasan, Sruthi Babu, Danielle Fassler, Jaymie Oentoro, Ji-Dong K Bai, Emanuel F. Petricoin III, Lynn M. Matrisian, Edik Matthew Blais, Natalia Marchenko, Felicia D. Allard, Wei Jiang, Brent Larson, Andrew Hendifar, Chao Chen, Shahira Abousamra, Dimitris Samaras, Tahsin Kurc, Joel Saltz, Luisa F. Escobar-Hoyos, Kenneth R. Shroyer
Transcript and protein signatures derived from shared molecular interactions across cancers are associated with mortality
Yelin Zhao, Xinxiu Li, Joseph Loscalzo, Martin Smelik, Oleg Sysoev, Yunzhang Wang, A. K. M. Firoj Mahmud, Dina Mansour Aly, Mikael Benson
Multi-omics integration highlights the role of ubiquitination in endometriosis fibrosis
Mengjie Yang, Hong Jiang, Xinyu Ding, Lu Zhang, Huaying Zhang, Jiahao Chen, Lijun Li, Xinqin He, Zhixiong Huang, Qionghua Chen
Synergistic effect of mesenchymal stem cell-derived extracellular vesicle and miR-137 alleviates autism-like behaviors by modulating the NF-κB pathway
Qian Qin, Zhiyan Shan, Lei Xing, Yutong Jiang, Mengyue Li, Linlin Fan, Xin Zeng, Xinrui Ma, Danyang Zheng, Han Wang, Hui Wang, Hao Liu, Shengjun Liang, Lijie Wu, Shuang Liang
Neuroprotective effects of apigenin on retinal ganglion cells in ischemia/reperfusion: modulating mitochondrial dynamics in in vivo and in vitro models
Jiawen Wu, Daowei zhang, Hongli Liu, Jufeng Li, Ting Li, Jihong Wu, Shenghai Zhang
Lipidomic studies revealing serological markers associated with the occurrence of retinopathy in type 2 diabetes
Mingqian He, Guixue Hou, Mengmeng Liu, Zhaoyi Peng, Hui Guo, Yue Wang, Jing Sui, Hui Liu, Xiaoming Yin, Meng Zhang, Ziyi Chen, Patrick C.N. Rensen, Liang Lin, Yanan Wang, Bingyin Shi
Lysosomal dysfunction and overload of nucleosides in thymidine phosphorylase deficiency of MNGIE
Jixiang Du, Fuchen Liu, Xihan Liu, Dandan Zhao, Dongdong Wang, Hongsheng Sun, Chuanzhu Yan, Yuying Zhao
Estetrol/GPER/SERPINB2 transduction signaling inhibits the motility of triple-negative breast cancer cells
Francesca Cirillo, Asia Spinelli, Marianna Talia, Domenica Scordamaglia, Maria Francesca Santolla, Fedora Grande, Bruno Rizzuti, Marcello Maggiolini, Céline Gérard, Rosamaria Lappano
Comprehensive genetic analysis of facioscapulohumeral muscular dystrophy by Nanopore long-read whole-genome sequencing
Mingtao Huang, Qinxin Zhang, Jiao Jiao, Jianquan Shi, Yiyun Xu, Cuiping Zhang, Ran Zhou, Wenwen Liu, Yixuan Liang, Hao Chen, Yan Wang, Zhengfeng Xu, Ping Hu
The multifaceted role of extracellular vesicles (EVs) in colorectal cancer: metastasis, immune suppression, therapy resistance, and autophagy crosstalk
Soheil Rahmati, Aysan Moeinafshar, Nima Rezaei
Differentially expressed genes associated with high metabolic tumor volume served as diagnostic markers and potential therapeutic targets for pancreatic cancer
Baek Gil Kim, Sung Hwan Lee, Yeonsue Jang, Suki Kang, Chang Moo Kang, Nam Hoon Cho
Defining albumin as a glycoprotein with multiple N-linked glycosylation sites
Kishore Garapati, Anu Jain, Benjamin J. Madden, Dong-Gi Mun, Jyoti Sharma, Rohit Budhraja, Akhilesh Pandey
Development of a machine learning-based model to predict prognosis of alpha-fetoprotein-positive hepatocellular carcinoma
Bingtian Dong, Hua Zhang, Yayang Duan, Senbang Yao, Yongjian Chen, Chaoxue Zhang
Autoimmune hepatitis displays distinctively high multi-antennary sialylation on plasma N-glycans compared to other liver diseases
Tamas Pongracz, Maaike Biewenga, Anna Eva Charlotte Stoelinga, Marco René Bladergroen, Simone Nicolardi, Leendert Adrianus Trouw, Manfred Wuhrer, Noortje de Haan, Bart van Hoek
Resveratrol attenuates inflammation and fibrosis in rheumatoid arthritis-associated interstitial lung disease via the AKT/TMEM175 pathway
Nannan Liu, Xuefei Fan, Yubao Shao, Suhuan Chen, Taorong Wang, Tao Yao, Xiaoyu Chen
PAX6/CXCL14 regulatory axis promotes the repair of corneal injury by enhancing corneal epithelial cell proliferation
Ruijue Ma, Yingxi Li, Xiaoli Dong, Yiming Zhang, Xiaosu Chen, Yue Zhang, Haohan Zou, Yan Wang
Unveiling heterogeneity in MSCs: exploring marker-based strategies for defining MSC subpopulations
Si Chen, Bowei Liang, Jianyong Xu
CCT6A facilitates lung adenocarcinoma progression and glycolysis via STAT1/HK2 axis
Shao-Kun Yu, Tao Yu, Yu-Ming Wang, Ao Sun, Jia Liu, Kai-Hua Lu
Presence of BAG3 protein in serum samples from patients affected by psoriasis
Antonia Falco, Anna Basile, Annunziata Raimondo, Giulia Guglielmi, Alessandra Rosati, Margot De Marco, Maria Caterina Turco, Maria Pascale, Serena Lembo
Combining germline, tissue and liquid biopsy analysis by comprehensive genomic profiling to improve the yield of actionable variants in a real-world cancer cohort
I. Vanni, L. Pastorino, V. Andreotti, D. Comandini, G. Fornarini, M. Grassi, A. Puccini, E. T. Tanda, A. Pastorino, V. Martelli, L. Mastracci, F. Grillo, F. Cabiddu, A. Guadagno, S. Coco, E. Allavena, F. Barbero, W. Bruno, B. Dalmasso, S. E. Bellomo, C. Marchiò, F. Spagnolo, S. Sciallero, E. Berrino, P. Ghiorzo
Enhanced anti-tumor efficacy with multi-transgene armed mesenchymal stem cells for treating peritoneal carcinomatosis
Yoon Khei Ho, Jun Yung Woo, Kin Man Loke, Lih-Wen Deng, Heng-Phon Too
Considerations from the organoid perspective of hepatocytes: culture organoid of bone or cartilage
Xiaofei Wang, Jihang Dai, Wenyong Fei, Hengjun Gao, Jingcheng Wang
Aberrant expression of NEDD4L disrupts mitochondrial homeostasis by downregulating CaMKKβ in diabetic kidney disease
Fei Han, Shi Wu, Ya Dong, Yanjie Liu, Bei Sun, Liming Chen
Microglia-derived exosomes selective sorted by YB-1 alleviate nerve damage and cognitive outcome in Alzheimer’s disease
Hong Wei, Zhuzhi Zhu, Yuhao Xu, Li Lin, Qi Chen, Yueqin Liu, Yuefeng Li, Xiaolan Zhu
Osteoarthritis patients exhibit an autonomic dysfunction with indirect sympathetic dominance
Rebecca Sohn, Tina Assar, Isabelle Kaufhold, Marco Brenneis, Sebastian Braun, Marius Junker, Frank Zaucke, Georg Pongratz, Zsuzsa Jenei-Lanzl
Revealing the pathogenesis of gastric intestinal metaplasia based on the mucosoid air-liquid interface
Simeng Liu, Huijuan Wen, Fazhan Li, Xia Xue, Xiangdong Sun, Fuhao Li, Ruoyu Hu, Huayuan Xi, Francesco Boccellato, Thomas F Meyer, Yang Mi, Pengyuan Zheng
Long non-coding RNA RP11-197K6.1 as ceRNA promotes colorectal cancer progression via miR-135a-5p/DLX5 axis
Mingkun Wang, Xuben Niu, Maihuan Wang, Peng Zheng, Xiaoya Liu, Zhen Cao, Chaojun Zhang
Immune repertoire sequencing for precision diagnosis in kidney transplantation
Lifei Liang, TingTing Chen, Tongyu Zhu, Cheng Yang
Dynamic radiological features predict pathological response after neoadjuvant immunochemotherapy in esophageal squamous cell carcinoma
Yuli Ruan, Yue Ma, Ming Ma, Chao Liu, Dan Su, Xin Guan, Rui Yang, Hong Wang, Tianqin Li, Yang Zhou, Jianqun Ma, Yanqiao Zhang
A multi-parametric prognostic model based on clinicopathologic features: vessels encapsulating tumor clusters and hepatic plates predict overall survival in hepatocellular carcinoma patients
Si-Ping Xiong, Chun-Hua Wang, Mei-fang Zhang, Xia Yang, Jing-Ping Yun, Li-Li Liu