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19615 Suchergebnisse für:

Epstein-Barr-Virus 

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  1. 01.05.2024 | OriginalPaper

    Clinicopathological characteristics and prognosis of Epstein-Barr virus–associated gastric cancer

    Gastric cancer (GC), which is the sixth-most-common cancer and the third leading cause of cancer-related death worldwide, is a significant public health concern, particularly in East Asia [ 1 ]. Thus, the role of Epstein-Barr virus (EBV) and …

  2. 03.05.2024 | Online First

    Highly sensitive detection of Epstein-Barr virus-infected cells by EBER flow FISH

    When Epstein-Barr virus (EBV) infection is suspected, identification of infected cells is important to understand the pathogenesis, determinine the treatment strategy, and predict the prognosis. We used the PrimeFlow™ RNA Assay Kit with a probe to …

  3. 01.04.2024 | OriginalPaper

    Single-Cell Transcriptomic Analysis of Epstein-Barr Virus-Associated Hemophagocytic Lymphohistiocytosis

    Epstein-Barr virus (EBV) infection can lead to infectious mononucleosis (EBV-IM) and, more rarely, EBV-associated hemophagocytic lymphohistiocytosis (EBV-HLH), which is characterized by a life-threatening hyperinflammatory cytokine storm with …

  4. 24.04.2024 | Online First

    EpsteinBarr virus positive gastric cancer: the pathological basis of CT findings and radiomics models prediction

    Gastric cancer (GC) is the fifth most common cancer and the fourth leading cause of cancer death globally [ 1 ]. The Cancer Genome Atlas (TCGA) project proposed a new molecular classification of GC in nature [ 2 ]. EpsteinBarr virus (EBV)-positive …

  5. 20.03.2024 | OriginalPaper

    A retrospective cohort study of Epstein-Barr virus infection status and systemic lupus erythematosus

    Systemic lupus erythematosus (SLE) is a devastating systemic autoimmune disease caused by immune dysregulation and characterized by the production of a large number of autoantibodies leading to multiple organ involvement. Signs and symptoms of SLE …

  6. 15.04.2024 | Online First

    Spontaneous regression of multiple solitary plasmacytoma harboring EpsteinBarr virus: a case report and literature review

    We report a rare case of spontaneous regression (SR) in an elderly untreated patient with multiple solitary plasmacytoma (MSP). Diagnosis of MSP was confirmed through surgical resection of the left nasal cavity mass and subsequent biopsy of the …

  7. 12.03.2024 | OriginalPaper

    Secondary hemophagocytic lymphohistiocytosis in pediatric patients with visceral leishmaniasis and Epstein-Barr virus infection

    Visceral leishmaniasis-associated hemophagocytic lymphohistiocytosis (VL-HLH) is indistinguishable from those of HLH of other etiologies due to the overlap symptoms, posing a serious threat to life. In this study, we aimed to provide insights for …

  8. 04.03.2024 | OriginalPaper

    Reactivation of EpsteinBarr virus among intensive care patients: a prospective observational study

    In recent years, studies have focused on the viral reactivation of cytomegalovirus (CMV) and herpes simplex virus (HSV) among immunocompetent patients in the intensive care unit (ICU). These studies have reported increased morbidity and mortality …

  9. Open Access 01.12.2024 | OriginalPaper

    Impact of plasma EpsteinBarr virus DNA in posttreatment nasopharyngeal carcinoma patients after SARS-CoV-2 infection

    Coronavirus disease 2019, commonly known as COVID-19, is a highly contagious respiratory illness caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) [ 1 ]. COVID-19 was first reported in December 2019 and has severely affected …

  10. Open Access 01.12.2024 | OriginalPaper

    Epstein-Barr virus-positive iris diffuse large B-cell lymphoma detected by metagenomic next-generation sequencing

    Intraocular lymphoma is a rare type of ocular malignancy and has two types: primary and secondary. Primary intraocular lymphoma (PIOL), a subset of primary central system lymphoma (PCNSL), affects the vitreous, retina, iris, ciliary body, choroid …

  11. Open Access 01.04.2024 | Letter

    Monozygotic Twins with MAGT1 Deficiency and EpsteinBarr virus-positive Classic Hodgkin Lymphoma Receiving anti-CD30 CAR T-cell Immunotherapy: A case Report

    Epstein-Barr virus (EBV)-positive classical Hodgkin lymphoma (cHL) is the most common malignancy in patients with “X-linked immunodeficiency with magnesium defect, EBV infection, and neoplasia” (XMEN). Aberrant expression of MAGT1 leads to XMEN, a …

  12. Open Access 01.12.2024 | OriginalPaper

    Recognizing the role of Epstein-Barr virus in gastric cancer: transcriptomic insights into malignancy modulation

    Gastric cancer (GC) remains a substantial global health issue, with over one million new cases reported in 2020 and an estimated 769,000 associated deaths [ 1 ]. Molecular studies related to this disease have shown that, like other cancers …

  13. Open Access 01.12.2024 | OriginalPaper

    Epstein-Barr virus-positive inflammatory follicular dendritic cell sarcoma with significant granuloma: case report and literature review

    Epstein-Barr virus-positive inflammatory follicular dendritic cell sarcoma (EBV+ IFDCS), also known as inflammatory pseudotumor-like follicular dendritic cell sarcoma (IPT-like FDCS), is a rare, low-grade malignant tumor that is infrequently …

  14. Open Access 01.12.2024 | OriginalPaper

    Retinitis after haematopoietic stem cell transplantation with multiple intraocular viral infections (cytomegalovirus, EpsteinBarr virus and herpes simplex virus)- a case report

    Acute lymphocytic leukaemia is a blood malignancy caused by malignant proliferation of lymphocytes in the blood and bone marrow [ 1 ]. The manifestations of acute lymphoblastic leukaemia is vary. Chemotherapy and haematopoietic stem cell …

  15. Open Access 11.01.2024 | OriginalPaper

    Sex-dependent different clinicopathological characterization of EpsteinBarr virus-associated gastric carcinoma: a large-scale study

    Although aggressive endoscopic screening in South Korea has led to a dramatic increase in early detection and treatment success rates over the past few decades, gastric cancer (GC) remains one of the most prevalent cancers not only in South Korea …

  16. Open Access 29.12.2023 | OriginalPaper

    Clinical characteristics and outcomes of Epstein-Barr virus viral load after allogeneic hematopoietic stem cell transplantation

    Epstein-Barr virus (EBV) reactivation can occur following allogenic hematopoietic stem cell transplantation (allo-HSCT). However, the clinical characteristics and outcomes of EBV-viral load are not well known. Thus, we retrospectively analyzed the …

  17. 12.09.2023 | OriginalPaper

    Prevalence of Epstein Barr Virus and Herpes Simplex Virus Among Human Papillomavirus Negative Oral Cancer Patients: A Cross-Sectional Study from South India

    The high incidence of oral carcinomas is due to its multifactorial etiology and the presence of various risk factors. Human Papillomavirus (HPV) has a proven role in the pathogenesis of oral carcinomas, but in the recent times there has been an …

  18. Open Access 01.02.2024 | OriginalPaper

    Presence of EpsteinBarr virus (EBV) antigens detected by sensitive methods has no influence on local immune environment in diffuse large B cell lymphoma

    EBV+ diffuse large B cell lymphoma (DLBCL) not otherwise specified (NOS) is a new entity confirmed by the World Health Organization (WHO) in 2017. In this new entity, the virus may contribute to a tolerogenic microenvironment. Traces of the virus

  19. 30.10.2023 | OriginalPaper

    Characterizing Epstein-Barr virus infection of the central nervous system in Zambian adults living with HIV

    The significance of Epstein-Barr virus (EBV) detection in the cerebrospinal spinal fluid (CSF) in people living with HIV (PLWH) is not entirely understood. The detection of EBV DNA may represent active central nervous system (CNS) infection …

  20. 07.08.2023 | Mononukleose | BriefCommunication

    Jüngere Geschwister schützen vor multipler Sklerose durch frühe Epstein-Barr-Virus-Primärexposition

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