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Erschienen in: Herz 1/2015

01.03.2015 | Review article

Mechanisms of new-onset atrial fibrillation complicating acute coronary syndrome

verfasst von: J. Wang, Y.-M. Yang, J. Zhu

Erschienen in: Herz | Sonderheft 1/2015

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Abstract

Atrial fibrillation (AF) is one of the most common arrhythmia complications of acute coronary syndrome (ACS). The incidence of new-onset AF is 2.3–37 %, and it is an important predictor of a patient’s morbidity, mortality, and prolonged hospitalization. Various risk factors for the development of new-onset AF after ACS have been identified, including: old age, higher Killip class, relevant history (e.g., hypertension), and enlarged left atrium. Insights into the pathophysiological mechanisms of new-onset AF have been provided by both experimental and clinical investigations and show that new-onset AF is multifactorial, involving atrial ischemia and atrial stretch, inflammation, autonomic nervous system activity, and hormone activation. An understanding of the mechanisms underlying new-onset AF complicating ACS can provide new insight of therapeutic importance.
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Metadaten
Titel
Mechanisms of new-onset atrial fibrillation complicating acute coronary syndrome
verfasst von
J. Wang
Y.-M. Yang
J. Zhu
Publikationsdatum
01.03.2015
Verlag
Urban & Vogel
Erschienen in
Herz / Ausgabe Sonderheft 1/2015
Print ISSN: 0340-9937
Elektronische ISSN: 1615-6692
DOI
https://doi.org/10.1007/s00059-014-4149-3

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