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European Journal of Pediatrics OnlineFirst articles

18.05.2024 | Correction

Correction to: Galectin-3 levels in children with cystic fibrosis

verfasst von:
Dilber Ademhan Tural, Nagehan Emiralioglu, Senay Akin, Didem Alboga, Beste Ozsezen, Halime Nayir Buyuksahin, Ismail Guzelkas, Merve Kasikci, Birce Sunman, Irem Gungor, Ebru Yalcin, Deniz Dogru, Nural Kiper, Ali Haydar Demirel, Ugur Ozcelik

17.05.2024 | BRIEF REPORT

Skin thickness in preterm neonates: relationship with skin bilirubin and predicted mortality

This study investigates the relationship between the thickness of skin in preterm infants and its link with bilirubin and mortality, as this may help understanding the potential deleterious effects of phototherapy. Observational, prospective …

verfasst von:
Silvia Foligno, Valeria Bisceglie, Barbara Loi, Daniele De Luca

17.05.2024 | Research

Agreement between quality of life assessed using family proxy and child self-reports among children with hematologic malignancy

Evidence-based literature recognizes that the different degrees of agreement between a child self-report and a proxy-report depend on the characteristics of the domains, the child’s age and illness, the proxy’s own perspective on QoL, and family …

verfasst von:
Thu Hang Tran Thi, Chung-Ying Lin, Mei-Chih Huang

16.05.2024 | RESEARCH

Association between preterm infant body composition in the first 3 months of life and preschool age: a cohort study

Compared with full-term infants, preterm infants have fat-free mass deficit in the first months of life, which increases the risk of metabolic diseases in the future. In this cohort of children born under 32-week gestational age or less than 1500 …

verfasst von:
Sylvia Reis Gonçalves Nehab, Letícia Duarte Villela, Andrea Dunshee Abranches, Saint Clair S. Gomes Junior, Fernanda Valente Mendes Soares, Maria Elisabeth Lopes Moreira

15.05.2024 | RESEARCH

Plasma profiles of inflammatory cytokines in children with moderate to severe traumatic brain injury: a prospective cohort study

The role of inflammatory cytokines in children with moderate to severe TBI (m-sTBI) is still incompletely understood. We aimed to investigate the associations between early plasma expression profiles of inflammatory cytokines and clinical outcomes …

verfasst von:
Haixin Huang, Guo Fu, Siwei Lu, Song Chen, Junming Huo, Yunni Ran, Changxue Xiao, Jian Chen, Dandan Pi, Fang Zhou, Hongxing Dang, Chengjun Liu, Yue-qiang Fu

Open Access 14.05.2024 | RESEARCH

Safety and efficacy of monthly high-dose vitamin D3 supplementation in children and adolescents with sickle cell disease

Little is known about the impact of vitamin D supplementation on hand grip strength (HGS) and health-related quality of life (HRQoL) in children and adolescents with sickle cell disease (SCD). We aimed to evaluate the safety and efficacy of …

verfasst von:
Diana Hanna, Doaa E. Kamal, Hebatallah M. Fawzy, Reham Abd Elkhalek

Open Access 14.05.2024 | RESEARCH

Assessing the quality of chest compressions with a DIY low-cost manikin (LoCoMan) versus a standard manikin: a quasi-experimental study in primary education

Extending the access to cardiopulmonary resuscitation (CPR) training to a wider public is an important step in increasing survivability of out-of-hospital cardiac arrest. However, often price and maintenance of CPR manikins are barriers that …

verfasst von:
Lucía Peixoto-Pino, Santiago Martínez Isasi, Martín Otero Agra, Tina Van Duijn, Javier Rico-Díaz, Antonio Rodriguez Núñez, Roberto Barcala Furelos

13.05.2024 | CORRESPONDENCE

Response to correspondence: ‘Why do children with oesophageal atresia have attention problems: complications should be considered’

verfasst von:
Anne-Fleur R. L. van Hal, Hanneke IJsselstijn, André B. Rietman

11.05.2024 | RESEARCH

Influence of morbidity, early nutritional intake, and total energy: protein ratio on longitudinal extrauterine growth restriction of very preterm newborns at term-equivalent age: an observational study

To evaluate the influence of early nutritional intake on the growth pattern of very preterm infants. This was an observational study including 109 newborns (< 32 weeks gestational age). Perinatal morbidities, nutritional therapy (first four weeks …

verfasst von:
Maria Dalva Barbosa Baker Méio, Giovana Gleysse de Miranda Salgado, Letícia Duarte Villela, Ana Carolina Carioca da Costa, Paola Azara Tabicas Lima, Brunna Grazziotti Milanesi, Maria Elisabeth Lopes Moreira

09.05.2024 | RESEARCH

Multisystemic inflammatory syndrome in children and the BNT162b2 vaccine: a nationwide cohort study

Multisystemic inflammatory syndrome in children (MIS-C) is a rare, severe, post-infectious hyperinflammatory condition that occurs after COVID-19 infection. In this study, we aimed to demonstrate the risk reduction of MIS-C and severe MIS-C after …

verfasst von:
Naama Schwartz, Ronit Ratzon, Itay Hazan, Deena Rachel Zimmerman, Shepherd Roee Singer, Janice Wasser, Tunie Dweck, Sharon Alroy-Preis

Open Access 09.05.2024 | RESEARCH

Foot and ankle problems in children and young people: a population-based cohort study

The aim of this research was to describe the epidemiology, presentation and healthcare use in primary care for foot and ankle problems in children and young people (CYP) across England. We undertook a population-based cohort study using data from …

verfasst von:
Emma Rezel-Potts, Catherine Bowen, Kate M. Dunn, Christopher I. Jones, Martin C. Gulliford, Stewart C. Morrison

Open Access 09.05.2024 | RESEARCH

Early postoperative beta-blockers are associated with improved cardiac output after late complete repair of tetralogy of Fallot: a retrospective cohort study

Tetralogy of Fallot is the most common cyanotic congenital heart disease. For decades, our institution has cared for humanitarian patients with late presentation of tetralogy of Fallot. They are characterized by severe right ventricular …

verfasst von:
Guillaume Maitre, Damien Schaffner, Sebastiano A. G. Lava, Marie-Hélène Perez, Stefano Di Bernardo

08.05.2024 | Research

Continuous renal replacement therapy and therapeutic plasma exchange in pediatric liver failure

Patients with acute liver failure (ALF) and acute on chronic liver failure (ACLF) have significant morbidity and mortality. They require extracorporeal blood purification modalities like continuous renal replacement therapy (CRRT) and therapeutic …

verfasst von:
Caroline Jackson, Kristen Carlin, Niviann Blondet, Ian Jordan, Larissa Yalon, Patrick J. Healey, Jordan M. Symons, Shina Menon

Open Access 08.05.2024 | BRIEF REPORT

Cardiac output calculation using the Liljestrand and Zander formula: is this method applicable during immediate transition after birth? — A post hoc analysis

The transition from intrauterine to extrauterine life is a critical period for neonates. Assessing the cardiovascular transition during this period immediately after birth is crucial but challenging. The present study compares adjusted estimated …

verfasst von:
Daniel Pfurtscheller, Bernhard Schwaberger, Nina Höller, Nariae Baik-Schneditz, Lukas Schober, Marlies Bruckner, Christoph Schlatzer, Berndt Urlesberger, Gerhard Pichler

07.05.2024 | Correspondence

Why do children with oesophageal atresia have attention problems: complications should be considered

verfasst von:
Yahong Wang, Yali Yang, Yupeng Ruan

Open Access 06.05.2024 | Correction

Correction to: Prospective multicenter evaluation of adherence to the Dutch guideline for children aged 0–16 years with fever without a source—febrile illness in children (FINCH) study

verfasst von:
Maya W. Keuning, Nikki N. Klarenbeek, Hidde J. Bout, Amber Broer, Melvin Draaijer, Jeroen Hol, Nina Hollander, Marieke Merelle, Amara Nassar-Sheikh Rashid, Charlotte Nusman, Emma Oostenbroek, Milan L. Ridderikhof, Manouck Roelofs, Ellen van Rossem, Sophie R. D. van der Schoor, Sarah M. Schouten, Pieter Taselaar, Koen Vasse, Anne-Marie van Wermeskerken, Julia M. J. van der Zande, Roy Zuurbier, Merijn W. Bijlsma, Dasja Pajkrt, Frans B. Plötz

Open Access 06.05.2024 | RESEARCH

Fecal calprotectin and platelet count predict histologic disease activity in pediatric ulcerative colitis: results from a projection-predictive feature selection

Especially for pediatric patients, proxies of mucosal inflammation are needed. The Pediatric Ulcerative Colitis Activity Index (PUCAI) has been established to predict clinical and endoscopic disease activity. However, histologic inflammation might …

verfasst von:
B. Schiller, E. Wirthgen, F. Weber, S. Schiller, M. Radke, M. Claßen, J. Däbritz, CEDATA-GPGE Study Group

Open Access 04.05.2024 | RESEARCH

The effect of NHFOV on hemodynamics in mild and moderately preterm neonates: a randomized clinical trial

The aim of this study is to study cardio-respiratory effects of nasal high-frequency oscillatory ventilation (NHFOV) vs. NCPAP as an initial mode of ventilation in moderate-late-preterm infants. A randomized controlled trial was conducted in NICU …

verfasst von:
Marwa Mohamed Farag, Mohamed Ahmed Amen Hassan, Nader Abd EL Moneim Fasseeh, Hesham Abd EL Rahim Ghazal

Open Access 03.05.2024 | RESEARCH

Genotype and clinical phenotype of children with Marfan syndrome in Southeastern Anatolia

The cardinal phenotypic hallmarks of Marfan syndrome (MFS) include cardiac, ocular, and skeletal abnormalities. Since the clinical phenotype of MFS is highly heterogeneous, with certain symptoms appearing as children age, the diagnostic process …

verfasst von:
Murat Karaoglan, Gulper Nacarkahya, Emel Hatun Aytac, Mehmet Keskin

03.05.2024 | RESEARCH

STEP-CD study: ustekinumab use in paediatric Crohn’s disease—a multicentre retrospective study from paediatric IBD Porto group of ESPGHAN

Ustekinumab is an effective therapy for adult Crohn’s disease (CD), but data in paediatric CD patients are scarce. The aim of the study was to describe the real-life effectiveness and safety of ustekinumab in paediatric CD. This is a multicentre …

verfasst von:
Gemma Pujol-Muncunill, Víctor Manuel Navas-López, Oren Ledder, Shlomi Cohen, Marina Lekar, Dan Turner, Kaija-Leena Kolho, Arie Levine, Nicholas M. Croft, Jiri Bronsky, Dror S. Shouval, Amit Assa, Rachel Harris, Fevronia Kiparissi, Marina Aloi, Nadeem Ahmad Afzal, Christos Tzivinikos, Josefa Barrio, Christoph Norden, Maria Jesús Balboa Vega, Stephan Buderus, Ana Fernández de Valderrama, Lissy de Ridder, Ruth García-Romero, Enrique Medina, César Sánchez, Marta Velasco, Saioa Vicente, David C. Wilson, Sandhia Naik, Ondrej Hradsky, Lucia Cococcioni, Javier Martin-de-Carpi