Skip to main content
Erschienen in: Herz 1/2021

02.03.2020 | Original articles

Incidence of permanent pacemaker implantation after valve replacement surgery

Cardiac structure and function at 1-year follow-up

verfasst von: Jiahui Song, M.M., Zhuo Liang, M.D., Yunlong Wang, M.D., Zhihong Han, M.D., Xuejun Ren, M.D.

Erschienen in: Herz | Sonderheft 1/2021

Einloggen, um Zugang zu erhalten

Abstract

Background

Our study aimed to explore the incidence and risk factors of permanent pacemaker implantation (PPI) after valve replacement surgery (VR). The influence of long-term pacemaker dependency on cardiac structure and function at the 1‑year follow-up was also assessed.

Methods

The demographic and surgical data of all consecutive patients who underwent VR between 2013 and 2016 were collected. Univariate and multivariate analyses were performed to identify variables independently associated with PPI after VR. A 1‑year follow-up was undertaken of patients who underwent dual-chambers pacemaker after VR because of complete atrioventricular block (AVB). Long-term pacemaker dependency and recovery of cardiac structure and function were evaluated.

Results

There were 5320 consecutive patients with VR. The incidence of postoperative PPI was 2.42%. Multivariate analysis indicated that among the 62 patients who underwent PPI due to AVB and sick sinus syndrome, isolated aortic valve replacement (AVR; OR: 2.24, p < 0.05), VR combined with ventricular septal defect (VSD) repair (OR: 6.78, p < 0.05), and VR with aortic root and arch surgery (OR: 4.14, p < 0.05) were independent predictors of PPI after surgery. In total, 89.6% (43/48) of the survivors showed pacemaker dependency. Of these 43 patients, 24 had enlarged left heart before VR. Compared with preoperative values, the left atrial and left ventricular end-diastolic diameter post-PPI decreased significantly, while left ventricular ejection fraction was not significantly different.

Conclusion

Isolated AVR, VR concomitant with VSD repair, and VR with aortic root and arch surgery are independent predictors of PPI after VR. The majority of patients do not recover from AVB disorders and there is no significant negative effect on recovery of cardiac structure and function.
Literatur
1.
Zurück zum Zitat Leyva F, Qiu T, McNulty D, Evison F, Marshall H, Gasparini M (2017) Long-term requirement for pacemaker implantation after cardiac valve replacement surgery. Heart Rhythm 14:529–534CrossRef Leyva F, Qiu T, McNulty D, Evison F, Marshall H, Gasparini M (2017) Long-term requirement for pacemaker implantation after cardiac valve replacement surgery. Heart Rhythm 14:529–534CrossRef
2.
Zurück zum Zitat Rene AG, Sastry A, Horowitz JM, Cheung J, Liu CF, Thomas G, Ip JE, Lerman BB, Markowitz SM (2013) Recovery of atrioventricular conduction after pacemaker placement following cardiac valvular surgery. J Cardiovasc Electrophysiol 24:1383–1387CrossRef Rene AG, Sastry A, Horowitz JM, Cheung J, Liu CF, Thomas G, Ip JE, Lerman BB, Markowitz SM (2013) Recovery of atrioventricular conduction after pacemaker placement following cardiac valvular surgery. J Cardiovasc Electrophysiol 24:1383–1387CrossRef
3.
Zurück zum Zitat Ferrari AD, Süssenbach CP, Guaragna JC, Piccoli Jda C, Gazzoni GF, Ferreira DK, Albuquerque LC, Goldani MA (2011) Atrioventricular block in the postoperative period of heart valve surgery: incidence, risk factors and hospital evolution. Rev Bras Cir Cardiovasc 26:364–372CrossRef Ferrari AD, Süssenbach CP, Guaragna JC, Piccoli Jda C, Gazzoni GF, Ferreira DK, Albuquerque LC, Goldani MA (2011) Atrioventricular block in the postoperative period of heart valve surgery: incidence, risk factors and hospital evolution. Rev Bras Cir Cardiovasc 26:364–372CrossRef
4.
Zurück zum Zitat Baraki H, Al Ahmad A, Jeng-Singh S, Saito S, Schmitto JD, Fleischer B, Haverich A, Kutschka I (2013) Pacemaker dependency after isolated aortic valve replacement: do conductance disorders recover over time? Interact Cardiovasc Thorac Surg 16:476–481CrossRef Baraki H, Al Ahmad A, Jeng-Singh S, Saito S, Schmitto JD, Fleischer B, Haverich A, Kutschka I (2013) Pacemaker dependency after isolated aortic valve replacement: do conductance disorders recover over time? Interact Cardiovasc Thorac Surg 16:476–481CrossRef
5.
Zurück zum Zitat Ribeiro V, Mota Garcia R, Frutuoso C, Melão F, Pereira M, Pinho P, Maciel MJ (2015) Permanent pacemaker implantation after aortic valve replacement: Long-term dependency or rhythm recovery? Rev Port Cardiol 34:529–533CrossRef Ribeiro V, Mota Garcia R, Frutuoso C, Melão F, Pereira M, Pinho P, Maciel MJ (2015) Permanent pacemaker implantation after aortic valve replacement: Long-term dependency or rhythm recovery? Rev Port Cardiol 34:529–533CrossRef
6.
Zurück zum Zitat Raza SS, Li JM, John R, Chen LY, Tholakanahalli VN, Mbai M, Adabag AS (2011) Long-term mortality and pacing outcomes of patients with permanent pacemaker implantation after cardiac surgery. Pacing Clin Electrophysiol 34:331–338CrossRef Raza SS, Li JM, John R, Chen LY, Tholakanahalli VN, Mbai M, Adabag AS (2011) Long-term mortality and pacing outcomes of patients with permanent pacemaker implantation after cardiac surgery. Pacing Clin Electrophysiol 34:331–338CrossRef
7.
Zurück zum Zitat Patel AM, Verma D, Jiang SF, Lau KY, Arrellano JL, Cain BS, Zaroff JG (2016) Permanent pacemaker implantation early after cardiac surgery: a descriptive study of pacemaker utility after one year of follow-up. J Card Surg 31:132–138CrossRef Patel AM, Verma D, Jiang SF, Lau KY, Arrellano JL, Cain BS, Zaroff JG (2016) Permanent pacemaker implantation early after cardiac surgery: a descriptive study of pacemaker utility after one year of follow-up. J Card Surg 31:132–138CrossRef
8.
Zurück zum Zitat Van Mieghem NM, Head SJ, de Jong W, van Domburg RT, Serruys PW, de Jaegere PP, Jordaens L, Takkenberg JJ, Bogers AJ, Kappetein AP (2012) Persistent annual permanent pacemaker implantation rate after surgical aortic valve replacement in patients with severe aortic stenosis. Ann Thorac Surg 94:1143–1149CrossRef Van Mieghem NM, Head SJ, de Jong W, van Domburg RT, Serruys PW, de Jaegere PP, Jordaens L, Takkenberg JJ, Bogers AJ, Kappetein AP (2012) Persistent annual permanent pacemaker implantation rate after surgical aortic valve replacement in patients with severe aortic stenosis. Ann Thorac Surg 94:1143–1149CrossRef
9.
Zurück zum Zitat Merin O, Ilan M, Oren A, Fink D, Deeb M, Bitran D, Silberman S (2009) Permanent pacemaker implantation following cardiac surgery: indications and long-term follow-up. Pacing Clin Electrophysiol 32:7–12CrossRef Merin O, Ilan M, Oren A, Fink D, Deeb M, Bitran D, Silberman S (2009) Permanent pacemaker implantation following cardiac surgery: indications and long-term follow-up. Pacing Clin Electrophysiol 32:7–12CrossRef
10.
Zurück zum Zitat Dawkins S, Hobson AR, Kalra PR, Tang AT, Monro JL, Dawkins KD (2008) Permanent pacemaker implantation after isolated aortic valve replacement: incidence, indications, and predictors. Ann Thorac Surg 85:108–112CrossRef Dawkins S, Hobson AR, Kalra PR, Tang AT, Monro JL, Dawkins KD (2008) Permanent pacemaker implantation after isolated aortic valve replacement: incidence, indications, and predictors. Ann Thorac Surg 85:108–112CrossRef
11.
Zurück zum Zitat Bagur R, Rodés-Cabau J, Gurvitch R, Dumont É, Velianou JL, Manazzoni J, Toggweiler S, Cheung A, Ye J, Natarajan MK, Bainey KR, DeLarochellière R, Doyle D, Pibarot P, Voisine P, Côté M, Philippon F, Webb JG (2012) Need for permanent pacemaker as a complication of transcatheter aortic valve implantation and surgical aortic valve replacement in elderly patients with severe aortic stenosis and similar baseline electrocardiographic findings. JACC Cardiovasc Interv 5:540–551CrossRef Bagur R, Rodés-Cabau J, Gurvitch R, Dumont É, Velianou JL, Manazzoni J, Toggweiler S, Cheung A, Ye J, Natarajan MK, Bainey KR, DeLarochellière R, Doyle D, Pibarot P, Voisine P, Côté M, Philippon F, Webb JG (2012) Need for permanent pacemaker as a complication of transcatheter aortic valve implantation and surgical aortic valve replacement in elderly patients with severe aortic stenosis and similar baseline electrocardiographic findings. JACC Cardiovasc Interv 5:540–551CrossRef
12.
Zurück zum Zitat Matthews IG, Fazal IA, Bates MG, Turley AJ (2011) In patients undergoing aortic valve replacement, what factors predict the requirement for permanent pacemaker implantation? Interact Cardiovasc Thorac Surg 12:475–479CrossRef Matthews IG, Fazal IA, Bates MG, Turley AJ (2011) In patients undergoing aortic valve replacement, what factors predict the requirement for permanent pacemaker implantation? Interact Cardiovasc Thorac Surg 12:475–479CrossRef
13.
Zurück zum Zitat Schurr UP, Berli J, Berdajs D, Häusler A, Dzemali O, Emmert M, Seifert B, Genoni M (2010) Incidence and risk factors for pacemaker implantation following aortic valve replacement. Interact Cardiovasc Thorac Surg 11:556–560CrossRef Schurr UP, Berli J, Berdajs D, Häusler A, Dzemali O, Emmert M, Seifert B, Genoni M (2010) Incidence and risk factors for pacemaker implantation following aortic valve replacement. Interact Cardiovasc Thorac Surg 11:556–560CrossRef
14.
Zurück zum Zitat Steyers CM 3rd, Khera R, Bhave P (2015) Pacemaker dependency after cardiac surgery: a systematic review of current evidence. PLoS ONE 10:e140340CrossRef Steyers CM 3rd, Khera R, Bhave P (2015) Pacemaker dependency after cardiac surgery: a systematic review of current evidence. PLoS ONE 10:e140340CrossRef
15.
Zurück zum Zitat Kim MH, Deeb GM, Eagle KA, Bruckman D, Pelosi F, Oral H, Sticherling C, Baker RL, Chough SP, Wasmer K, Michaud GF, Knight BP, Strickberger SA, Morady F (2001) Complete atrioventricular block after valvular heart surgery and the timing of pacemaker implantation. Am J Cardiol 87:649–651, A10CrossRef Kim MH, Deeb GM, Eagle KA, Bruckman D, Pelosi F, Oral H, Sticherling C, Baker RL, Chough SP, Wasmer K, Michaud GF, Knight BP, Strickberger SA, Morady F (2001) Complete atrioventricular block after valvular heart surgery and the timing of pacemaker implantation. Am J Cardiol 87:649–651, A10CrossRef
16.
Zurück zum Zitat Onalan O, Crystal A, Lashevsky I, Khalameizer V, Lau C, Goldman B, Fremes S, Newman D, Lukomsky M, Crystal E (2008) Determinants of pacemaker dependency after coronary and/or mitral or aortic valve surgery with long-term follow-up. Am J Cardiol 101:203–208CrossRef Onalan O, Crystal A, Lashevsky I, Khalameizer V, Lau C, Goldman B, Fremes S, Newman D, Lukomsky M, Crystal E (2008) Determinants of pacemaker dependency after coronary and/or mitral or aortic valve surgery with long-term follow-up. Am J Cardiol 101:203–208CrossRef
17.
Zurück zum Zitat Saito M, Iannaccone A, Kaye G, Negishi K, Kosmala W, Marwick TH, PROTECT-PACE investigators (2015) Effect of right ventricular pacing on right ventricular mechanics and tricuspid regurgitation in patients with high-grade atrioventricular block and sinus rhythm (from the protection of left ventricular function during right ventricular pacing study). Am J Cardiol 116:1875–1882CrossRef Saito M, Iannaccone A, Kaye G, Negishi K, Kosmala W, Marwick TH, PROTECT-PACE investigators (2015) Effect of right ventricular pacing on right ventricular mechanics and tricuspid regurgitation in patients with high-grade atrioventricular block and sinus rhythm (from the protection of left ventricular function during right ventricular pacing study). Am J Cardiol 116:1875–1882CrossRef
18.
Zurück zum Zitat Kiehl EL, Makki T, Kumar R, Gumber D, Kwon DH, Rickard JW, Kanj M, Wazni OM, Saliba WI, Varma N, Wilkoff BL, Cantillon DJ (2016) Incidence and predictors of right ventricular pacing-induced cardiomyopathy in patients with complete atrioventricular block and preserved left ventricular systolic function. Heart Rhythm 13:2272–2278CrossRef Kiehl EL, Makki T, Kumar R, Gumber D, Kwon DH, Rickard JW, Kanj M, Wazni OM, Saliba WI, Varma N, Wilkoff BL, Cantillon DJ (2016) Incidence and predictors of right ventricular pacing-induced cardiomyopathy in patients with complete atrioventricular block and preserved left ventricular systolic function. Heart Rhythm 13:2272–2278CrossRef
19.
Zurück zum Zitat Khurshid S, Epstein AE, Verdino RJ, Lin D, Goldberg LR, Marchlinski FE, Frankel DS (2014) Incidence and predictors of right ventricular pacing-induced cardiomyopathy. Heart Rhythm 11:1619–1625CrossRef Khurshid S, Epstein AE, Verdino RJ, Lin D, Goldberg LR, Marchlinski FE, Frankel DS (2014) Incidence and predictors of right ventricular pacing-induced cardiomyopathy. Heart Rhythm 11:1619–1625CrossRef
20.
Zurück zum Zitat Ebert M, Jander N, Minners J, Blum T, Doering M, Bollmann A, Hindricks G, Arentz T, Kalusche D, Richter S (2016) Long-Term Impact of Right Ventricular Pacing on Left Ventricular Systolic Function in Pacemaker Recipients With Preserved Ejection Fraction: Results From a Large Single-Center Registry. J Am Heart Assoc 5:e3485CrossRef Ebert M, Jander N, Minners J, Blum T, Doering M, Bollmann A, Hindricks G, Arentz T, Kalusche D, Richter S (2016) Long-Term Impact of Right Ventricular Pacing on Left Ventricular Systolic Function in Pacemaker Recipients With Preserved Ejection Fraction: Results From a Large Single-Center Registry. J Am Heart Assoc 5:e3485CrossRef
21.
Zurück zum Zitat Kaye GC, Linker NJ, Marwick TH, Pollock L, Graham L, Pouliot E, Poloniecki J, Gammage M, Protect-Pace trial investigators (2015) Effect of right ventricular pacing lead site on left ventricular function in patients with high-grade atrioventricular block: results of the Protect-Pace study. Eur Heart J 36:856–862CrossRef Kaye GC, Linker NJ, Marwick TH, Pollock L, Graham L, Pouliot E, Poloniecki J, Gammage M, Protect-Pace trial investigators (2015) Effect of right ventricular pacing lead site on left ventricular function in patients with high-grade atrioventricular block: results of the Protect-Pace study. Eur Heart J 36:856–862CrossRef
Metadaten
Titel
Incidence of permanent pacemaker implantation after valve replacement surgery
Cardiac structure and function at 1-year follow-up
verfasst von
Jiahui Song, M.M.
Zhuo Liang, M.D.
Yunlong Wang, M.D.
Zhihong Han, M.D.
Xuejun Ren, M.D.
Publikationsdatum
02.03.2020
Verlag
Springer Medizin
Erschienen in
Herz / Ausgabe Sonderheft 1/2021
Print ISSN: 0340-9937
Elektronische ISSN: 1615-6692
DOI
https://doi.org/10.1007/s00059-020-04895-2

Weitere Artikel der Sonderheft 1/2021

Herz 1/2021 Zur Ausgabe

„Jeder Fall von plötzlichem Tod muss obduziert werden!“

17.05.2024 Plötzlicher Herztod Nachrichten

Ein signifikanter Anteil der Fälle von plötzlichem Herztod ist genetisch bedingt. Um ihre Verwandten vor diesem Schicksal zu bewahren, sollten jüngere Personen, die plötzlich unerwartet versterben, ausnahmslos einer Autopsie unterzogen werden.

Hirnblutung unter DOAK und VKA ähnlich bedrohlich

17.05.2024 Direkte orale Antikoagulanzien Nachrichten

Kommt es zu einer nichttraumatischen Hirnblutung, spielt es keine große Rolle, ob die Betroffenen zuvor direkt wirksame orale Antikoagulanzien oder Marcumar bekommen haben: Die Prognose ist ähnlich schlecht.

Schlechtere Vorhofflimmern-Prognose bei kleinem linken Ventrikel

17.05.2024 Vorhofflimmern Nachrichten

Nicht nur ein vergrößerter, sondern auch ein kleiner linker Ventrikel ist bei Vorhofflimmern mit einer erhöhten Komplikationsrate assoziiert. Der Zusammenhang besteht nach Daten aus China unabhängig von anderen Risikofaktoren.

Semaglutid bei Herzinsuffizienz: Wie erklärt sich die Wirksamkeit?

17.05.2024 Herzinsuffizienz Nachrichten

Bei adipösen Patienten mit Herzinsuffizienz des HFpEF-Phänotyps ist Semaglutid von symptomatischem Nutzen. Resultiert dieser Benefit allein aus der Gewichtsreduktion oder auch aus spezifischen Effekten auf die Herzinsuffizienz-Pathogenese? Eine neue Analyse gibt Aufschluss.

Update Kardiologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.