Ausgabe 6/2023
Inhalt (12 Artikel)
Molecular integrators of stress and aging: the example of FKBP5
Anthony S. Zannas
Physiological β-amyloid clearance by the liver and its therapeutic potential for Alzheimer’s disease
Yuan Cheng, Chen-Yang He, Ding-Yuan Tian, Si-Han Chen, Jun-Rong Ren, Hao-Lun Sun, Man-Yu Xu, Cheng-Rong Tan, Dong-Yu Fan, Jie-Ming Jian, Pu-Yang Sun, Gui-Hua Zeng, Ying-Ying Shen, An-Yu Shi, Wang-Sheng Jin, Xian-Le Bu, Hong-Ming Liu, Yu-Ming Xu, Jun Wang, Yan-Jiang Wang
TREM2 gene expression associations with Alzheimer’s disease neuropathology are region-specific: implications for cortical versus subcortical microglia
Rebecca L. Winfree, Mabel Seto, Logan Dumitrescu, Vilas Menon, Philip De Jager, Yanling Wang, Julie Schneider, David A. Bennett, Angela L. Jefferson, Timothy J. Hohman
Defects in lysosomal function and lipid metabolism in human microglia harboring a TREM2 loss of function mutation
Fabia Filipello, Shih-Feng You, Farzaneh S. Mirfakhar, Sidhartha Mahali, Bryan Bollman, Mariana Acquarone, Olena Korvatska, Jacob A. Marsh, Anirudh Sivaraman, Rita Martinez, Claudia Cantoni, Luca De Feo, Laura Ghezzi, Miguel A. Minaya, Arun Renganathan, Anil G. Cashikar, Jun-Ichi Satoh, Wandy Beatty, Abhirami K. Iyer, Marina Cella, Wendy H. Raskind, Laura Piccio, Celeste M. Karch
Loss of hypothalamic MCH decreases food intake in amyotrophic lateral sclerosis
Matei Bolborea, Pauline Vercruysse, Tselmen Daria, Johanna C. Reiners, Najwa Ouali Alami, Simon J. Guillot, Stéphane Dieterlé, Jérôme Sinniger, Jelena Scekic-Zahirovic, Amela Londo, Hippolyte Arcay, Marc-Antoine Goy, Claudia Nelson de Tapia, Dietmar R. Thal, Kazumoto Shibuya, Ryo Otani, Kimihito Arai, Satoshi Kuwabara, Albert C. Ludolph, Francesco Roselli, Deniz Yilmazer-Hanke, Luc Dupuis
C-terminal frameshift variant of TDP-43 with pronounced aggregation-propensity causes rimmed vacuole myopathy but not ALS/FTD
Pedro Ervilha Pereira, Nika Schuermans, Antoon Meylemans, Pontus LeBlanc, Lauren Versluys, Katie E. Copley, Jack D. Rubien, Christopher Altheimer, Myra Peetermans, Elke Debackere, Olivier Vanakker, Sandra Janssens, Jonathan Baets, Kristof Verhoeven, Martin Lammens, Sofie Symoens, Boel De Paepe, Sami J. Barmada, James Shorter, Jan L. De Bleecker, Elke Bogaert, Bart Dermaut
Ganglioglioma with adverse clinical outcome and atypical histopathological features were defined by alterations in PTPN11/KRAS/NF1 and other RAS-/MAP-Kinase pathway genes
Lucas Hoffmann, Roland Coras, Katja Kobow, Javier A. López-Rivera, Dennis Lal, Costin Leu, Imad Najm, Peter Nürnberg, Jochen Herms, Patrick N. Harter, Christian G. Bien, Thilo Kalbhenn, Markus Müller, Tom Pieper, Till Hartlieb, Manfred Kudernatsch, Hajo Hamer, Sebastian Brandner, Karl Rössler, Ingmar Blümcke, Samir Jabari
Transcriptome analysis stratifies second-generation non-WNT/non-SHH medulloblastoma subgroups into clinically tractable subtypes
Andrey Korshunov, Konstantin Okonechnikov, Daniel Schrimpf, Svenja Tonn, Martin Mynarek, Jan Koster, Philipp Sievers, Till Milde, Felix Sahm, David T. W. Jones, Andreas von Deimling, Stefan M. Pfister, Marcel Kool
Clinical applicability of miR517a detection in liquid biopsies of ETMR patients
Sibylle Madlener, Julia Furtner, Natalia Stepien, Daniel Senfter, Lisa Mayr, Maximilian Zeyda, Leon Gramss, Barbara Aistleitner, Sabine Spiegl-Kreinecker, Elisa Rivelles, Christian Dorfer, Karl Rössler, Thomas Czech, Amedeo A. Azizi, Andreas Peyrl, Daniela Lötsch-Gojo, Leonhard Müllauer, Christine Haberler, Irene Slavc, Johannes Gojo
The perils of contact sport: pathologies of diffuse brain swelling and chronic traumatic encephalopathy neuropathologic change in a 23-year-old rugby union player
Edward B. Lee, Claire Kennedy-Dietrich, Jennian F. Geddes, James A. R. Nicoll, Tamas Revesz, Douglas H. Smith, William Stewart
Correction to: Ganglioglioma with adverse clinical outcome and atypical histopathological features were defined by alterations in PTPN11/KRAS/NF1 and other RAS-/MAP-Kinase pathway genes
Lucas Hoffmann, Roland Coras, Katja Kobow, Javier A. López-Rivera, Dennis Lal, Costin Leu, Imad Najm, Peter Nürnberg, Jochen Herms, Patrick N. Harter, Christian G. Bien, Thilo Kalbhenn, Markus Müller, Tom Pieper, Till Hartlieb, Manfred Kudernatsch, Hajo Hamer, Sebastian Brandner, Karl Rössler, Ingmar Blümcke, Samir Jabari
Correction to: Dysregulation of astrocytic Ca2+ signaling and gliotransmitter release in mouse models of α-synucleinopathies
Carmen Nanclares, Jonah Poynter, Hector A. Martell-Martinez, Scott Vermilyea, Alfonso Araque, Paulo Kofuji, Michael K. Lee, Ana Covelo