Introduction
Methods
Search strategy
EMBASE |
1. progressive supranuclear palsy/exp 2. corticobasal degeneration/exp 3. corticobasal syndrome/exp 4. tauopathy/exp 5. atypical parkinsonism/exp 6. atypical parkinsonian syndrome/exp 7. 1 OR 2 OR 3 OR 4 OR 5 OR 6 8. epidemiology/exp 9. incidence/exp 10. prevalence/exp 11. 8 OR 9 OR 10 12. 7 AND 11 |
Pubmed |
1. “progressive supranuclear palsy”[All Fields] 2. “corticobasal syndrome”[All Fields] 3. “corticobasal degeneration” [All Fields] 4. “tauopathy” [All Fields] 5. “atypical parkinsonism” [All Fields] 6. 1 OR 2 OR 3 OR 4 OR 5 7. “incidence”[All Fields] 8. “prevalence”[All Fields] 9. “epidemiology” [All Fields] 10. “population-based” [All Fields] 11. 7 OR 8 OR 9 OR 10 12. 7 AND 11 |
Study selection
Data extraction and study quality
Data analysis
Results
Identification and description of studies
Study | Case definition | Population definition | Cases | Condition studied | ||
---|---|---|---|---|---|---|
PSP | CBS | |||||
1 | Radhnakrisnan 1988 | Residents diagnosed with PSP based on clinical features of supranuclear palsy of vertical gaze, axial dystonia in extension, and pseudobulbar palsy with dysarthria and dysphagia between January 1983 and December 1986 | Population of Benghazi, Libya | 6 | Multiple neuro conditions | |
2 | Golbe 1988 | Residents alive on 1st May 1986 who met outlined criteria for PSP as follows: all of onset after 40, progressive course, bradykinesia, supranuclear gaze palsy with 3 of: dysarthria or dysphagia, axial > limb rigidity, neck in a posture of extension, tremor minimal or absent, frequent falls or early gait disturbance, pyramidal tract signs without early or prominent cerebellar signs, unexplained polyneuropathy, dysautonomia other than isolated postural hypotension | Residents of Middlesex and Somerset County, New Jersey, USA based on population data from the 1980 US Census | 11 | PSP | |
3 | De Rijk 1995 | Residents alive in June 1993, who screened positive for parkinsonism and had PSP confirmed (diagnostic criteria not specified) following structured evaluation by study physicians | Residents of Ommoord, a Rotterdam suburb, aged over 55 in June 1993 | 1 | PD | |
4 | Bower 1997 | Residents ascertained by H-ICDA codes of parkinsonism and neurodegenerative disease and diagnosed with PSP based on criteria by Collins et al. by study neurologists between 1st January 1976 and 31st December 1990 | Residents of Olmsted County between 1976–1990 | 16 | PSP and MSA | |
5 | Wermuth 1997 | Residents with parkinsonism or using dopaminergic medication and subsequently found to have Richardson’s syndrome on assessment with a study neurologist who were alive on 1st of July 1995 | Residents of the Faroe Islands alive on 1st of July 1995 | 2 | PD | |
6 | Chio 1998 | Residents identified by ICD codes of Parkinson’s disease and dopaminergic medication use found to have PSP on review with a study neurologist who were alive on 20th October 1991 | Residents of the Socio-Sanitary District of Cossato alive on 20th October 1991 | 2 | PD | |
7 | Schrag 1999 | Prevalence: Cases identified by screening of computer records for entries related to Parkinsonism and PSP who met NINDS-SPSP criteria on examination and review of video by study neurologists who were alive on 1st July 1997 Incidence: Prevalence rates divided by the mean disease duration derived from previous studies | Patients registered at 15 UK general practices in London | 6 | PSP and MSA | |
8 | Nath 2001 | (1) UK residents with a diagnosis of PSP notified to national surveillance services, patient advocacy, and Office of National Statistics(UK) who were alive on 1st January 1999 (2) UK residents identified by multiple screening methods, categorised as possible or probable PSP based on review of medical records and examination by study neurologist using the NINDS-SPSP criteria who were alive on 1st January 1999 (3) UK residents identified by screening of GP and hospital records with parkinsonism with PSP according to NINDS-SPSP criteria on review by study physician | (1) Population of the United Kingdom based on mid-1998 census figures (2) Regional population in the North of England based on mid-1998 census figures (3) Population served by 35 participating general practices in the North of England as reported by the Newcastle and North Tyneside Health Authority | (1) 577 (2) 80 (3) 17 | PSP | |
9 | Yamada 2001 | Participants screening positive for cognitive impairment on a screening exam and subsequently diagnosed with PSP on examination by study neurologist (criteria not reported) alive on 1st January 1998 | Residents of Amino-cho, Kyoto prefecture who were alive on 1st January 1998 | 1 | Dementia | |
10 | Harvey 2003 | Residents with a diagnosis of dementia, where the illness began before the age of 65. Diagnosis of CBS based on psychiatrist review of medical records | Residents of four London boroughs aged 30–64 | 2 | Dementia | |
11 | Zhang 2003 | Residents screened positive for parkinsonism and were subsequently found to have PSP (by criteria from Collins et al.) on review by a study physician | Residents of 27 geographically defined communities in Greater Beijing, China aged over 55, and alive on 31st December 1997 | 1 | Parkinsonism | |
12 | Bergareche 2004 | Cases who screened positive for Parkinsonism and were subsequently identified as having PSP on review by a study physician alive on prevalence day in 1996 | A random sample of 2000 people aged 65 or older in two municipalities in the Bidasao region of the Basque Country | 1 | Parkinsonism | |
13 | Kawashima 2004 | Participants with PSP diagnosed by neurologists or identified as having supranuclear gaze palsy or parkinsonism with dementia and subsequently diagnosed based on the NINDS-SPSP criteria by a study neurologist | Residents of Yonago City, Japan alive on 1st April 1999 | 8 | PSP | |
14 | Tan 2004 | Participants who screened positive for Parkinson’s disease and subsequently diagnosed with PSP or CBD by a study Movement Disorders specialist using the criteria of NIND-SPSP and Kumar et al | Residents of 4 districts in Singapore aged 50 years or above | 1 | PD | |
15 | Wermuth 2008 | Residents identified as having Parkinsonism with a diagnosis of PSP (by NINDS-SPSP criteria) or CBS (based on criteria by Riley et al.) on review by a study neurologist who were alive on 1st July 2005 | Population of the Faroe Islands based on the Faroese Registry of Residents 1st January 2005 | 2 | PD | |
16 | Linder 2010 | Residents between 1st January 2004 and 31st December 2007 with parkinsonism and PSP (NINDS-SPSP criteria) or CBS (Litvan et al. criteria) on review by a study movement disorders specialist | Residents of the catchment of Umea University Hospital, Sweden, between 1st January 2004 and 31st December 2007 | 6 | Parkinsonism | |
17 | Tatari 2010 | Patients diagnosed with PSP | Residents of Buenos Aires | NR | Parkinsonism | |
18 | Winter 2010 | Residents with parkinsonism and diagnosis of PSP (based on NINDS-SPSP criteria) or CBS (based on criteria by Lang et al.) following evaluation by a study physician with a first diagnosis between 1st July 2006 and 31st December 2008 | Residents of the northeast district of Moscow between 1st July 2006 and 31st December 2008 | 5 | 1 | Parkinsonism |
19 | Osaki 2011 | Residents who were alive on 1st of November 2007with a diagnosis or suspicion of a Parkinsonian condition with a diagnosis of PSP (by NINDS-SPSP criteria) or CBS (by Kumar et al. criteria) on evaluation by a study neurologist | Residents of Koban district based on the census of 1st October 2005 | 12 | 6 | Parkinsonism |
20 | Nakashita 2011 | Residents > 65 with parkinsonism on door-to-door screening and a diagnosis of PSP (based on NINDS-SPSP criteria) who were alive on 1st October 2010 | Residents of the town of Ama-cho, aged 65 or older, alive and legally residing in the town on 1st October 2009 | 1 | Parkinsonism | |
21 | Savica 2013 | Residents identified in computer screening for Parkinsonism and specific Parkinsonian disorders with the diagnosis of PSP (based on criteria by Collins et al.) or CBD (based on criteria by Maraganore et al.) confirmed on review of records by a study movement disorders specialist where the initial diagnosis was made between 1st January 1991 to 31st December 2005 | Residents of Olmsted County, Minnesota from 1st January 1991 to 31st December 2005 | 16 | 4 | Parkinsonism |
22 | Caslake 2014 | Participants with suspected new onset parkinsonism between April 2006 and April 2009 with a diagnosis of PSP (based on NINDS-SPSP criteria) or CBS (criteria not specified) following assessment by a study physician | People registered with one of 37 primary care practices in Aberdeen between April 2006 and April 2009 | 20 | 2 | Parkinsonism |
23 | Withall 2014 | Residents with a history of memory, behavioural, and/or language symptoms before the age of 65 years and persistent cognitive impairment for at least 6 months with confirmation of PSP/CBS diagnosis based on medical note review using DSM-IV criteria | Residents of four local government areas in Eastern Sydney < 65 years of age | 3 | 1 | Dementia |
24 | Khedr 2015 | Participants who scored positive for parkinsonism on a screening questionnaire and had a diagnosis of PSP/CBS confirmed on review by a study neurologist according to DSM-IV criteria (CBS) and based on criteria by Boeve et al. (PSP) who were alive on 31st August 2013 | A random sample of households in 10 areas of the Qena governate, Egypt | 2 | Parkinsonism | |
25 | Coyle-Gilchrist 2016 | Prevalence: Residents with a diagnosis of frontotemporal lobar degeneration including PSP (by NNIPPS criteria) or CBS (by Armstrong criteria) alive on 1st January 2014 Incidence: Residents with a diagnosis of frontotemporal lobar degeneration including PSP (by NNIPPS criteria) or CBS (by Armstrong criteria) first diagnosed between 1st January 2013 and 31st December 2014 | The population of a catchment area including Cambridgeshire and Norfolk according to the 2013 UK Office for National Statistics midyear estimate | 48 | 48 | FTLD |
26 | Takigawa 2016 | Residents alive on 1st October 2010 and with diagnoses of Parkinson’s disease or atypical Parkinsonism and diagnosis of PSP (based on NINDS-SPSP criteria or by Williams et al. for variant subtypes) at interview with a study neurologist | Residents of Yonago City, Japan who were alive on 1st October 2010 | 25 | PSP | |
27 | Fleury 2018 | Prevalence: Residents diagnosed with parkinsonism including PSP (according to NINS-SPSP criteria) and CBS (by Armstrong et al. criteria) who were alive on 1st January 2013 (in the case of prevalence) Incidence: Residents who were diagnosed with parkinsonism including PSP (according to NINS-SPSP criteria) and CBS (by Armstrong et al. criteria) diagnosed between 1st January 2009 to 31st December 2012 (in the case of incidence) | Residents of the canton of Geneva from 1st January 2003 to 31st December 2012 | 39 | 14 | Parkinsonism |
28 | Calo-Perxas 2019 | Diagnoses of PSP reported to the Registry of Dementias of Girona (ReDeGi), between 2007 and 2016 | Population served by the Health Region of Girona in Northeastern Catalonia between based on census figures between 2007 and 2016 | 33 | Uncommon Dementias including PSP and CBS | |
29 | Logroscino 2019 | Residents with new diagnoses of frontotemporal lobar degeneration between 1st January 2017 and 31st December 2017, with diagnoses of PSP (defined by NINDS-SPSP criteria) or CBS (Armstrong et al. criteria) confirmed on review by a study dementia expert | Residents of Lecce and Brescia between 1st January 2017 and 31st December 2017 | 9 | 7 | FTLD |
30 | Stang 2020 | Residents with new diagnoses of Parkinsonism from 1st January 1991 to 31st December 2005 and subsequently diagnosed as PSP (by MDS 2017 criteria) or CBS (by Armstrong et al. criteria) by review of medical records by a study movement disorders expert | Residents of Olmsted County, Minnesota with the person-years at risk extrapolated from the Rochester Epidemiology Project | 8 | 3 | PSP/CBS |
31 | Viscidi 2020 | Patients in a national electronic medical record database with 1 or more codes for PSP | Patients registered in a national electronic medical record database (CPRD GOLD) | 704 | PSP | |
32 | Viscidi 2021 | Patients registered in the MarketScan databases with ≥ 1 month of enrolment between 1st October 2015 and 31st October 2017 with ICD-10 (G23.1) and ICD-9 (333.0) codes corresponding to a diagnosis of PSP | People registered in large set of US insurance databases with a month or more of enrolment between 1st October 2015 and 31st October 2017 | 630 | PSP |