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01.02.2016 | Leitlinien der DGU und des BDU

S2e-Leitlinie der Deutschen Urologen

Instrumentelle Therapie des benignen Prostatasyndroms

verfasst von: PD Dr. Dr. T. Bschleipfer, FEBU, T. Bach, R. Berges, K. Dreikorn, C. Gratzke, S. Madersbacher, M.-S. Michel, R. Muschter, M. Oelke, O. Reich, C. Tschuschke, K. Höfner

Erschienen in: Die Urologie | Ausgabe 2/2016

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Zusammenfassung

Diese Übersicht fasst die relevanten Aspekte der S2e-Leitlinie der Deutschen Urologen zur instrumentellen Therapie des benignen Prostatasyndroms (BPS) zusammen. Empfehlungen zu offenen und transurethralen Verfahren (TUR-P, bipolare TUR-P, TUI-P, HE-TUMT, TUNA und den unterschiedlichen Laserverfahren) werden gegeben. Darüber hinaus finden sich Empfehlungen zu intraprostatischen Stents und Injektionstherapien. Die Arbeit stellt zudem detailliert den Einfluss der unterschiedlichen Therapieoptionen auf die Blasenauslassobstruktion (BOO) dar.

Abrams PH (1978) The urodynamic changes after prostatectomy. Urol Int 33:181CrossRef

Abrams PH, Farrar DJ, Turner-Warwick RT et al (1979) The results of prostatectomy: a symptomatic and urodynamic analysis of 152 patients. J Urol 121:640–642PubMed

Ahmed M, Bell T, Lawrence WT et al (1997) Transurethral microwave thermotherapy (Prostatron version 2.5) compared with transurethral resection of the prostate for the treatment of benign prostatic hyperplasia: a randomized, controlled, parallel study. Br J Urol 79:181–185PubMedCrossRef

Aho TF, Gilling PJ, Kennett KM et al (2005) Holmium laser bladder neck incision versus holmium enucleation of the prostate as outpatient procedures for prostates less than 40 grams: a randomized trial. J Urol 174:210–214PubMedCrossRef

Ahyai SA, Lehrich K, Kuntz RM (2007) Holmium laser enucleation versus transurethral resection of the prostate: 3-year follow-up results of a randomized clinical trial. Eur Urol 52:1456–1463PubMedCrossRef

Armitage JN, Cathcart PJ, Rashidian A et al (2007) Epithelializing stent for benign prostatic hyperplasia: a systematic review of the literature. J Urol 177:1619–1624PubMedCrossRef

AWMF (2014) AWMF-Register-Nummer 043-035, Aktualisierung 2014. AWMF, Düsseldorf. http://www.awmf.org/uploads/tx_szleitlinien/043-035m_S2e_Therapie_benignes_Prostatatasyndrom_2014_11.pdf

AWMF (2014) AWMF, Düsseldorf. http://www.awmf.org/fileadmin/user_upload/Leitlinien/043_D_Ges_fuer_Urologie/043-035e1_S2e_Therapie_benignes_Prostatatasyndrom_2014_11.pdf

AWMF (2014) AWMF, Düsseldorf. http://www.awmf.org/fileadmin/user_upload/Leitlinien/043_D_Ges_fuer_Urologie/043-035e2_S2e_Therapie_benignes_Prostatatasyndrom_2014_11.pdf

10.

AWMF (2014) AWMF, Düsseldorf. http://www.awmf.org/fileadmin/user_upload/Leitlinien/043_D_Ges_fuer_Urologie/043-035e3_S2e_Therapie_benignes_Prostatatasyndrom_2014_11.pdf

11.

Bach T, Herrmann TR, Ganzer R et al (2007) RevoLix vaporesection of the prostate: initial results of 54 patients with a 1-year follow-up. World J Urol 25:257–262PubMedCrossRef

12.

Bach T, Herrmann TR, Haecker A et al (2009) Thulium: yttrium-aluminium-garnet laser prostatectomy in men with refractory urinary retention. BJU Int 104:361–364PubMedCrossRef

13.

Bach T, Muschter R, Sroka R et al (2012) Laser treatment of benign prostatic obstruction: basics and physical differences. Eur Urol 61:317–325PubMedCrossRef

14.

Bach T, Netsch C, Haecker A et al (2010) Thulium: YAG laser enucleation (VapoEnucleation) of the prostate: safety and durability during intermediate-term follow-up. World J Urol 28:39–43PubMedCrossRef

15.

Bach T, Netsch C, Pohlmann L et al (2011) Thulium: YAG vapoenucleation in large volume prostates. J Urol 186:2323–2327PubMedCrossRef

16.

Bach T, Wendt-Nordahl G, Michel MS et al (2009) Feasibility and efficacy of Thulium: YAG laser enucleation (VapoEnucleation) of the prostate. World J Urol 27:541–545PubMedCrossRef

17.

Berges R, Dreikorn K, Hofner K et al (2009) Therapy of benign prostate syndrome (BPS): guidelines of the German Urologists (DGU). Urologe A 48:1503–1516PubMedCrossRef

18.

Berges R, Dreikorn K, Höfner K et al (2009) Diagnostik und Differenzialdiagnostik des benignen Prostatasyndroms (BPS): Leitlinien der Deutschen Urologen. Urologe A 48:1356–1360 (1362–1354)PubMedCrossRef

19.

Berges R, Dreikorn K, Höfner K et al (2009) Therapie des benignen Prostatasyndroms (BPS): Leitlinien der Deutschen Urologen. Urologe A 48:1503–1516PubMedCrossRef

20.

Bouchier-Hayes DM, Van Appledorn S, Bugeja P et al (2010) A randomized trial of photoselective vaporization of the prostate using the 80-W potassium-titanyl-phosphate laser vs transurethral prostatectomy, with a 1-year follow-up. BJU Int 105:964–969PubMedCrossRef

21.

Bouza C, Lopez T, Magro A et al (2006) Systematic review and meta-analysis of Transurethral Needle Ablation in symptomatic Benign Prostatic Hyperplasia. BMC Urol 6:14PubMedPubMedCentralCrossRef

22.

Brubaker L, Richter HE, Visco A et al (2008) Refractory idiopathic urge urinary incontinence and botulinum A injection. J Urol 180:217–222PubMedPubMedCentralCrossRef

23.

Bryan NP, Hastie KJ, Chapple CR (2000) Randomised prospective trial of contact laser prostatectomy (CLAP) versus visual laser coagulation of the prostate (VLAP) for the treatment of benign prostatic hyperplasia. 2-year follow-up. Eur Urol 38:265–271PubMedCrossRef

24.

Campo B, Bergamaschi F, Corrada P et al (1997) Transurethral needle ablation (TUNA) of the prostate: a clinical and urodynamic evaluation. Urology 49:847–850PubMedCrossRef

25.

Cannon A, Wildt M de, Abrams PH et al (1995) Urodynamics and laser prostatectomy. World J Urol 13:134–136PubMedCrossRef

26.

Capitan C, Blazquez C, Martin MD et al (2011) GreenLight HPS120-W laser vaporization versus transurethral resection of the prostate for the treatment of lower urinary tract symptoms due to benign prostatic hyperplasia: a randomized clinical trial with 2-year follow-up. Eur Urol 60:734–739PubMedCrossRef

27.

Castro JE (1973) The effect of prostatectomy on the symptoms and signs of benign prostatic hypertrophy. Br J Urol 45:428–431PubMedCrossRef

28.

Cavarretta L, Scremin E, Cucciarre G et al (2003) High-energy microwave thermotherapy in the treatment of benign prostatic hyperplasia. Urol Int 71:10–15PubMedCrossRef

29.

Chiang PH, Chen CH, Kang CH et al (2010) GreenLight HPS laser 120-W versus diode laser 200-W vaporization of the prostate: comparative clinical experience. Lasers Surg Med 42:624–629PubMedCrossRef

30.

Choe JM, Sirls LT (1996) High-energy visual laser ablation of the prostate in men with urinary retention: pressure-flow analysis. Urology 48:584–588PubMedCrossRef

31.

Cummings JM, Parra RO, Boullier JA (1995) Laser prostatectomy: initial experience and urodynamic follow-up. Urology 45:414–418 (discussion 418–420)PubMedCrossRef

32.

Dahlstrand C, Grundtman S, Pettersson S (1997) High-energy transurethral microwave thermotherapy for large severely obstructing prostates and the use of biodegradable stents to avoid catheterization after treatment. Br J Urol 79:907–909PubMedCrossRef

33.

Dmochowski R, Chapple C, Nitti VW et al (2010) Efficacy and safety of onabotulinumtoxinA for idiopathic overactive bladder: a double-blind, placebo controlled, randomized, dose ranging trial. J Urol 184:2416–2422PubMedCrossRef

34.

Dorflinger T, Jensen FS, Krarup T et al (1992) Transurethral prostatectomy compared with incision of the prostate in the treatment of prostatism caused by small benign prostate glands. Scand J Urol Nephrol 26:333–338PubMedCrossRef

35.

Dunsmuir WD, McFarlane JP, Tan A et al (2003) Gyrus bipolar electrovaporization vs transurethral resection of the prostate: a randomized prospective single-blind trial with 1 y follow-up. Prostate Cancer Prostatic Dis 6:182–186PubMedCrossRef

36.

Edwards L, Powell C (1982) An objective comparison of transurethral resection and bladder neck incision in the treatment of prostatic hypertrophy. J Urol 128:325–327PubMed

37.

Elmansy HM, Elzayat E, Elhilali MM (2010) Holmium laser ablation versus photoselective vaporization of prostate less than 60 cc: long-term results of a randomized trial. J Urol 184:2023–2028PubMedCrossRef

38.

Elzayat E, Habib E, Elhilali M (2006) Holmium laser enucleation of the prostate in patients on anticoagulant therapy or with bleeding disorders. J Urol 175:1428–1432PubMedCrossRef

39.

Elzayat EA, Al-Mandil MS, Khalaf I et al (2009) Holmium laser ablation of the prostate versus photoselective vaporization of prostate 60 cc or less: short-term results of a prospective randomized trial. J Urol 182:133–138PubMedCrossRef

40.

Elzayat EA, Habib EI, Elhilali MM (2005) Holmium laser enucleation of the prostate: a size-independent new „gold standard“. Urology 66:108–113PubMedCrossRef

41.

Fagerstrom T, Nyman CR, Hahn RG (2010) Bipolar transurethral resection of the prostate causes less bleeding than the monopolar technique: a single-centre randomized trial of 202 patients. BJU Int 105:1560–1564PubMedCrossRef

42.

Flynn MK, Amundsen CL, Perevich M et al (2009) Outcome of a randomized, double-blind, placebo controlled trial of botulinum A toxin for refractory overactive bladder. J Urol 181:2608–2615PubMedPubMedCentralCrossRef

43.

Fu WJ, Zhang X, Yang Y et al (2010) Comparison of 2-microm continuous wave laser vaporesection of the prostate and transurethral resection of the prostate: a prospective nonrandomized trial with 1-year follow-up. Urology 75:194–199PubMedCrossRef

44.

Gallucci M, Puppo P, Perachino M et al (1998) Transurethral electrovaporization of the prostate vs. transurethral resection. Results of a multicentric, randomized clinical study on 150 patients. Eur Urol 33:359–364PubMedCrossRef

45.

Gemeinsamer Bundesausschuss ‚G-BA‘ (2010) Nichtmedikamentöse lokale Verfahren zur Behandlung des benignen Prostatasyndroms. Abschlussbericht. G-BA, Berlin

46.

Gesenberg A, Sintermann R (1998) Management of benign prostatic hyperplasia in high risk patients: long-term experience with the Memotherm stent. J Urol 160:72–76PubMedCrossRef

47.

Ghalayini IF, Al-Ghazo MA, Pickard RS (2005) A prospective randomized trial comparing transurethral prostatic resection and clean intermittent self-catheterization in men with chronic urinary retention. BJU Int 96:93–97PubMedCrossRef

48.

Gill HS, Kabalin JN (1993) Urodynamic evaluation of patients in a randomized study of transurethral resection versus laser prostatectomy: pre-operative and one year follow-up. Neurourol Urodyn 12:372

49.

Gilling PJ, Cass CB, Malcolm A et al (1998) Holmium laser resection of the prostate versus neodymium:yttrium-aluminum-garnet visual laser ablation of the prostate: a randomized prospective comparison of two techniques for laser prostatectomy. Urology 51:573–577PubMedCrossRef

50.

Gilling PJ, Kennett KM, Fraundorfer MR (2000) Holmium laser resection v transurethral resection of the prostate: results of a randomized trial with 2 years of follow-up. J Endourol 14:757–760PubMedCrossRef

51.

Gilling PJ, Mackey M, Cresswell M et al (1999) Holmium laser versus transurethral resection of the prostate: a randomized prospective trial with 1-year followup. J Urol 162:1640–1644PubMedCrossRef

52.

Gilling PJ, Wilson LC, King CJ et al (2012) Long-term results of a randomized trial comparing holmium laser enucleation of the prostate and transurethral resection of the prostate: results at 7 years. BJU Int 109:408–411PubMedCrossRef

53.

Gotoh M, Yoshikawa Y, Kondo AS et al (1999) Prognostic value of pressure-flow study in surgical treatment of benign prostatic obstruction. World J Urol 17:274–278PubMedCrossRef

54.

Gratzke C, Schlenker B, Seitz M et al (2007) Complications and early postoperative outcome after open prostatectomy in patients with benign prostatic enlargement: results of a prospective multicenter study. J Urol 177:1419–1422PubMedCrossRef

55.

Guazzoni G, Bergamaschi F, Montorsi F et al (1993) Prostatic UroLume Wallstent for benign prostatic hyperplasia patients at poor operative risk: clinical, uroflowmetric and ultrasonographic patterns. J Urol 150:1641–1646 (discussion 1646–1647)PubMed

56.

Guazzoni G, Montorsi F, Coulange C et al (1994) A modified prostatic UroLume Wallstent for healthy patients with symptomatic benign prostatic hyperplasia: a European Multicenter Study. Urology 44:364–370PubMedCrossRef

57.

Gupta N, Sivaramakrishna, Kumar R et al (2006) Comparison of standard transurethral resection, transurethral vapour resection and holmium laser enucleation of the prostate for managing benign prostatic hyperplasia of > 40 g. BJU Int 97:85–89PubMedCrossRef

58.

Hamann MF, Naumann CM, Seif C et al (2008) Functional outcome following photoselective vaporisation of the prostate (PVP): urodynamic findings within 12 months follow-up. Eur Urol 54:902–907PubMedCrossRef

59.

Hamidi Madani A, Enshaei A, Heidarzadeh A et al (2013) Transurethral intraprostatic Botulinum toxin-A injection: a novel treatment for BPH refractory to current medical therapy in poor surgical candidates. World J Urol 31:235–239CrossRef

60.

Harbour R, Miller J (2001) A new system for grading recommendations in evidence based guidelines. BMJ 323:334–336PubMedPubMedCentralCrossRef

61.

Hauser S, Rogenhofer S, Ellinger J et al (2012) Thulium laser (Revolix) vapoenucleation of the prostate is a safe procedure in patients with an increased risk of hemorrhage. Urol Int 88:390–394PubMedCrossRef

62.

Hellstrom P, Lukkarinen O, Kontturi M (1986) Bladder neck incision or transurethral electroresection for the treatment of urinary obstruction caused by a small benign prostate? A randomized urodynamic study. Scand J Urol Nephrol 20:187–192PubMedCrossRef

63.

Hochreiter W, Hugonnet C, Studer UE (1999) Transurethral resection of the prostate with the Holmium contact laser. Progress in treatment of benign prostatic hypertrophy? Urologe A 38:156–161PubMedCrossRef

64.

Höfner K, Bach T, Berges R et al (2014) S2e Leitlinie, Therapie des Benignen Prostatasyndroms (BPS), Aktualisierung 2014. Arbeitskreis Benignes Prostatasyndrom (AK BPS) (Hrsg), Books on Demand, ISBN 978-3-95780-025-1

65.

Horasanli K, Silay MS, Altay B et al (2008) Photoselective potassium titanyl phosphate (KTP) laser vaporization versus transurethral resection of the prostate for prostates larger than 70 mL: a short-term prospective randomized trial. Urology 71:247–251PubMedCrossRef

66.

Horninger W, Janetschek G, Watson G et al (1997) Are contact laser, interstitial laser, and transurethral ultrasound-guided laser-induced prostatectomy superior to transurethral prostatectomy? Prostate 31:255–263PubMedCrossRef

67.

Huidobro C, Larson B, Mynderse S et al (2009) Characterizing Prostiva RF treatments of the prostate for BPH with gadolinium-enhanced MRI. ScientificWorldJournal 9:10–16PubMedCrossRef

68.

Hung CT, Lin AT, Chen KK et al (1995) The subjective assessment and pressure-flow study of outcome of surgical treatment for patients with prostatism and high voiding pressure. Zhonghua Yi Xue Za Zhi (Taipei) 56:186–191

69.

Iori F, Franco G, Leonardo C et al (2008) Bipolar transurethral resection of prostate: clinical and urodynamic evaluation. Urology 71:252–255PubMedCrossRef

70.

Issa MM (2008) Technological advances in transurethral resection of the prostate: bipolar versus monopolar TURP. J Endourol 22:1587–1595PubMedCrossRef

71.

James MJ, Harriss DR, Ceccherini A et al (1995) A urodynamic study of laser ablation of the prostate and a comparison of techniques. Br J Urol 76:179–183PubMedCrossRef

72.

Jensen KM, Jorgensen JB, Mogensen P (1988) Urodynamics in prostatism. I. Prognostic value of uroflowmetry. Scand J Urol Nephrol 114 (Suppl):63–71

73.

Jensen KM, Jorgensen TB, Mogensen P (1996) Long-term predictive role of urodynamics: an 8-year follow-up of prostatic surgery for lower urinary tract symptoms. Br J Urol 78:213–218PubMedCrossRef

74.

Johnson TMJ, Busby-Whitehead J, Ashford-Works C et al (1998) Promoting help-seeking behavior for urinary inconctince. J Appl Gerontol 17:419–441CrossRef

75.

Jung P, Schäfer W, Jakse G (1995) Visual laser ablation of the prostate. Efficacy according to prostate size evaluated by urodynamics and compared to TUR. Neurourol Urodyn 14:570

76.

Kabalin JN, Gill HS, Bite G et al (1995) Comparative study of laser versus electrocautery prostatic resection: 18-month followup with complex urodynamic assessment. J Urol 153:94–97PubMedCrossRef

77.

Kaplan SA, Chiou RK, Morton WJ et al (1995) Long-term experience utilizing a new balloon expandable prostatic endoprosthesis: the Titan stent. North American Titan Stent Study Group. Urology 45:234–240PubMedCrossRef

78.

Karaman MI, Kaya C, Ozturk M et al (2005) Comparison of transurethral vaporization using PlasmaKinetic energy and transurethral resection of prostate: 1-year follow-up. J Endourol 19:734–737PubMedCrossRef

79.

Kaya C, Ilktac A, Gokmen E et al (2007) The long-term results of transurethral vaporization of the prostate using plasmakinetic energy. BJU Int 99:845–848PubMedCrossRef

80.

Krambeck AE, Handa SE, Lingeman JE (2010) Holmium laser enucleation of the prostate for prostates larger than 175 grams. J Endourol 24:433–437PubMedCrossRef

81.

Kuntz RM (2006) Current role of lasers in the treatment of benign prostatic hyperplasia (BPH). Eur Urol 49:961–969PubMedCrossRef

82.

Kuntz RM, Ahyai S, Lehrich K et al (2004) Transurethral holmium laser enucleation of the prostate versus transurethral electrocautery resection of the prostate: a randomized prospective trial in 200 patients. J Urol 172:1012–1016PubMedCrossRef

83.

Kuntz RM, Lehrich K, Ahyai SA (2008) Holmium laser enucleation of the prostate versus open prostatectomy for prostates greater than 100 grams: 5-year follow-up results of a randomised clinical trial. Eur Urol 53:160–166PubMedCrossRef

84.

Kuo HC (2005) Prostate botulinum A toxin injection – an alternative treatment for benign prostatic obstruction in poor surgical candidates. Urology 65:670–674PubMedCrossRef

85.

Kuo HC, Liu HT (2009) Therapeutic effects of add-on botulinum toxin A on patients with large benign prostatic hyperplasia and unsatisfactory response to combined medical therapy. Scand J Urol Nephrol 43:206–211PubMedCrossRef

86.

Larsen EH, Dorflinger T, Gasser TC et al (1987) Transurethral incision versus transurethral resection of the prostate for the treatment of benign prostatic hypertrophy. A preliminary report. Scand J Urol Nephrol 104 (Suppl):83–86

87.

Larson BT, Netto N, Huidobro C et al (2006) Intraprostatic injection of alcohol gel for the treatment of benign prostatic hyperplasia: preliminary clinical results. ScientificWorldJournal 6:2474–2480PubMedCrossRef

88.

Leonardi R (2009) Preliminary results on selective light vaporization with the side-firing 980 nm diode laser in benign prostatic hyperplasia: an ejaculation sparing technique. Prostate Cancer Prostatic Dis 12:277–280PubMedCrossRef

89.

Lourenco T, Armstrong N, N’Dow J et al (2008) Systematic review and economic modelling of effectiveness and cost utility of surgical treatments for men with benign prostatic enlargement. Health Technol Assess 12:iii (ix–x 1–146, 169–515)PubMedCrossRef

90.

Lourenco T, Pickard R, Vale L et al (2008) Minimally invasive treatments for benign prostatic enlargement: systematic review of randomised controlled trials. BMJ 337:1662CrossRef

91.

Lourenco T, Shaw M, Fraser C et al (2010) The clinical effectiveness of transurethral incision of the prostate: a systematic review of randomised controlled trials. World J Urol 28:23–32PubMedCrossRef

92.

Lukacs B, Loeffler J, Bruyere F et al (2012) Photoselective vaporization of the prostate with greenlight 120-W laser compared with monopolar transurethral resection of the prostate: a multicenter randomized controlled trial. Eur Urol 61:1165–1173PubMedCrossRef

93.

Madersbacher S, Marberger M (1999) Is transurethral resection of the prostate still justified? BJU Int 83:227–237PubMedCrossRef

94.

Mamoulakis C, Trompetter M, Rosette J de la (2009) Bipolar transurethral resection of the prostate: the ‚golden standard‘ reclaims its leading position. Curr Opin Urol 19:26–32PubMedCrossRef

95.

Mamoulakis C, Ubbink DT, Rosette JJ de la (2009) Bipolar versus monopolar transurethral resection of the prostate: a systematic review and meta-analysis of randomized controlled trials. Eur Urol 56:798–809PubMedCrossRef

96.

Manieri C, Tubaro A, Trucchi A et al (1995) Urodynamic evaluation of high energy transurethral microwave thermotherapy (v. 2.5) in the treatment of BPH. Urodinamica 5:127

97.

Marberger M, Chartier-Kastler E, Egerdie B et al (2013) A randomized double-blind placebo-controlled phase 2 dose-ranging study of onabotulinumtoxinA in men with benign prostatic hyperplasia. Eur Urol 63:496–503PubMedCrossRef

98.

Marchal C, Perez JE, Herrera B et al (2012) The use of Botulinum toxin in benign prostatic hyperplasia. Neurourol Urodyn 31:86–92PubMedCrossRef

99.

Matsuta Y, Ichioka K, Terada N et al (2003) Interstitial laser coagulation for benign prostatic hyperplasia: clinical results of the Indigo diode laser system. Hinyokika Kiyo 49:195–200PubMed

100.

Mattiasson A, Wagrell L, Schelin S et al (2007) Five-year follow-up of feedback microwave thermotherapy versus TURP for clinical BPH: a prospective randomized multicenter study. Urology 69:91–96PubMedCrossRef

101.

McVary KT, Roehrborn CG, Avins AL et al (2011) Update on AUA guideline on the management of benign prostatic hyperplasia. J Urol 185:1793–1803PubMedCrossRef

102.

Meyhoff HH, Gleason DM, Bottaccini MR (1989) The effects of transurethral resection on the urodynamics of prostatism. J Urol 142:785–789PubMed

103.

Meyhoff HH, Nordling J, Hald T (1984) Urodynamic evaluation of transurethral versus transvesical prostatectomy. A randomized study. Scand J Urol Nephrol 18:27–35PubMedCrossRef

104.

Minardi D, Garofalo F, Yehia M et al (2001) Pressure-flow studies in men with benign prostatic hypertrophy before and after treatment with transurethral needle ablation. Urol Int 66:89–93PubMedCrossRef

105.

Montorsi F, Naspro R, Salonia A et al (2004) Holmium laser enucleation versus transurethral resection of the prostate: results from a 2-center, prospective, randomized trial in patients with obstructive benign prostatic hyperplasia. J Urol 172:1926–1929PubMedCrossRef

106.

Moody JA, Lingeman JE (2001) Holmium laser enucleation for prostate adenoma greater than 100 gm.: comparison to open prostatectomy. J Urol 165:459–462PubMedCrossRef

107.

Mottet N, Anidjar M, Bourdon O et al (1999) Randomized comparison of transurethral electroresection and holmium: YAG laser vaporization for symptomatic benign prostatic hyperplasia. J Endourol 13:127–130PubMedCrossRef

108.

Naspro R, Suardi N, Salonia A et al (2006) Holmium laser enucleation of the prostate versus open prostatectomy for prostates > 70 g: 24-month follow-up. Eur Urol 50:563–568PubMedCrossRef

109.

Neal DE, Ramsden PD, Sharples L et al (1989) Outcome of elective prostatectomy (see comments). BMJ 299:762–767PubMedPubMedCentralCrossRef

110.

Netsch C, Bach T, Pohlmann L et al (2012) Comparison of 120–200 W 2 mum thulium:yttrium-aluminum-garnet vapoenucleation of the prostate. J Endourol 26:224–229PubMedCrossRef

111.

Netsch C, Pohlmann L, Herrmann TR et al (2012) 120-W 2-microm thulium:yttrium-aluminium-garnet vapoenucleation of the prostate: 12-month follow-up. BJU Int 110:96–101PubMedCrossRef

112.

Nielsen H (1988) Transurethral prostatomy versus transurethral prostatectomy in benign prostatic hypertrophy. a prospective randomised study. Br J Urol 61:435–438PubMedCrossRef

113.

Oelke M, Bachmann A, Descazeaud A et al (2012) Guidelines on management of male lower urinary tract symptoms (LUTS), incl. benign prostatic obstruction (BPO). In: Office Members of the European Association of Urology (EAU) Guidelines (Hrsg) EAU Guidelines, edition presented at the 27th EAU Annual Congress, Paris

114.

Oesterling JE, Kaplan SA, Epstein HB et al (1994) The North American experience with the UroLume endoprosthesis as a treatment for benign prostatic hyperplasia: long-term results. The North American UroLume Study Group. Urology 44:353–362PubMedCrossRef

115.

Ou R, You M, Tang P et al (2010) A randomized trial of transvesical prostatectomy versus transurethral resection of the prostate for prostate greater than 80 mL. Urology 76:958–961PubMedCrossRef

116.

Pereira-Correia JA, Moraes Sousa KD de, Santos JB et al (2012) GreenLight HPS120-W laser vaporization vs transurethral resection of the prostate (60 mL): a 2-year randomized double-blind prospective urodynamic investigation. BJU Int 110:1184–1189PubMedCrossRef

117.

Reich O, Bachmann A, Siebels M et al (2005) High power (80 W) potassium-titanyl-phosphate laser vaporization of the prostate in 66 high risk patients. J Urol 173:158–160PubMedCrossRef

118.

Reich O, Gratzke C, Bachmann A et al (2008) Morbidity, mortality and early outcome of transurethral resection of the prostate: a prospective multicenter evaluation of 10,654 patients. J Urol 180:246–249PubMedCrossRef

119.

Reich O, Gratzke C, Stief CG (2006) Techniques and long-term results of surgical procedures for BPH. Eur Urol 49:970–978PubMedCrossRef

120.

Riehmann M, Knes JM, Heisey D et al (1995) Transurethral resection versus incision of the prostate: a randomized, prospective study. Urology 45:768–775PubMedCrossRef

121.

Rieken M, Ebinger Mundorff N, Bonkat G et al (2010) Complications of laser prostatectomy: a review of recent data. World J Urol 28:53–62PubMedCrossRef

122.

Rigatti L, Naspro R, Salonia A et al (2006) Urodynamics after TURP and HoLEP in urodynamically obstructed patients: are there any differences at 1 year of follow-up? Urology 67:1193–1198PubMedCrossRef

123.

Roehrborn CG, Burkhard FC, Bruskewitz RC et al (1999) The effects of transurethral needle ablation and resection of the prostate on pressure flow urodynamic parameters: analysis of the United States randomized study. J Urol 162:92–97PubMedCrossRef

124.

Roos NP, Wennberg JE, Malenka DJ et al (1989) Mortality and reoperation after open and transurethral resection of the prostate for benign prostatic hyperplasia. N Engl J Med 320:1120–1124PubMedCrossRef

125.

Rosario DJ, Woo H, Potts KL et al (1997) Safety and efficacy of transurethral needle ablation of the prostate for symptomatic outlet obstruction. Br J Urol 80:579–586PubMedCrossRef

126.

Rosette JJ de la, Wildt MJ de, Hofner K et al (1996) High energy thermotherapy in the treatment of benign prostatic hyperplasia: results of the European Benign Prostatic Hyperplasia Study Group. J Urol 156:97–102PubMedCrossRef

127.

Rosette JJ de la, Wildt MJ de, Hofner K et al (1996) Pressure-flow study analyses in patients treated with high energy thermotherapy. J Urol 156:1428–1433PubMedCrossRef

128.

Ruszat R, Seitz M, Wyler SF et al (2008) GreenLight laser vaporization of the prostate: single-center experience and long-term results after 500 procedures. Eur Urol 54:893–901PubMedCrossRef

129.

Ruszat R, Wyler S, Forster T et al (2007) Safety and effectiveness of photoselective vaporization of the prostate (PVP) in patients on ongoing oral anticoagulation. Eur Urol 51:1031–1041PubMedCrossRef

130.

Saemi AM, Folsom JB, Plante MK (2008) Injection therapy for prostatic disease: a renaissance concept. Indian J Urol 24:329–335PubMedPubMedCentralCrossRef

131.

Sahai A, Khan MS, Dasgupta P (2007) Efficacy of botulinum toxin-A for treating idiopathic detrusor overactivity: results from a single center, randomized, double-blind, placebo controlled trial. J Urol 177:2231–2236PubMedCrossRef

132.

Saporta L, Aridogan IA, Erlich N et al (1996) Objective and subjective comparison of transurethral resection, transurethral incision and balloon dilatation of the prostate. A prospective study. Eur Urol 29:439–445PubMed

133.

Seitz M, Sroka R, Gratzke C et al (2007) The diode laser: a novel side-firing approach for laser vaporisation of the human prostate – immediate efficacy and 1-year follow-up. Eur Urol 52:1717–1722PubMedCrossRef

134.

Seki N, Nomura H, Yamaguchi A et al (2008) Effects of photoselective vaporization of the prostate on urodynamics in patients with benign prostatic hyperplasia. J Urol 180:1024–1029PubMedCrossRef

135.

Shah DK, Paul EM, Badlani GH et al (2003) 11-year outcome analysis of endourethral prosthesis for the treatment of recurrent bulbar urethral stricture. J Urol 170:1255–1258PubMedCrossRef

136.

Sirls LT, Ganabathi K, Zimmern PE et al (1993) Transurethral incision of the prostate: an objective and subjective evaluation of long-term efficacy. J Urol 150:1615–1621PubMed

137.

Skolarikos A, Papachristou C, Athanasiadis G et al (2008) Eighteen-month results of a randomized prospective study comparing transurethral photoselective vaporization with transvesical open enucleation for prostatic adenomas greater than 80 cc. J Endourol 22:2333–2340PubMedCrossRef

138.

Soonawalla PF, Pardanani DS (1992) Transurethral incision versus transurethral resection of the prostate. A subjective and objective analysis. Br J Urol 70:174–177PubMedCrossRef

139.

Spangberg A, Teriö H, Ask P et al (1991) Pressure/flow studies preoperatively and postoperatively in patients with benign prostatic hypertrophy: estimation of the urethral pressure/flow relation and urethral elasticity. Neurourol Urodyn 10:139CrossRef

140.

Steele GS, Sleep DJ (1997) Transurethral needle ablation of the prostate: a urodynamic based study with 2-year followup. J Urol 158:1834–1838PubMedCrossRef

141.

Szlauer R, Gotschl R, Razmaria A et al (2009) Endoscopic vaporesection of the prostate using the continuous-wave 2-microm thulium laser: outcome and demonstration of the surgical technique. Eur Urol 55:368–375PubMedCrossRef

142.

Tan A, Liao C, Mo Z et al (2007) Meta-analysis of holmium laser enucleation versus transurethral resection of the prostate for symptomatic prostatic obstruction. Br J Surg 94:1201–1208PubMedCrossRef

143.

Tan AH, Gilling PJ, Kennett KM et al (2003) A randomized trial comparing holmium laser enucleation of the prostate with transurethral resection of the prostate for the treatment of bladder outlet obstruction secondary to benign prostatic hyperplasia in large glands (40–200 grams). J Urol 170:1270–1274PubMedCrossRef

144.

Slaa E te, Mooibroek JJ, Reijke TM de et al (1996) Laser treatment of the prostate using the Urolase fiber: the Dutch experience. J Urol 156:420–425CrossRef

145.

Thangasamy IA, Chalasani V, Bachmann A et al (2012) Photoselective vaporisation of the prostate using 80-W and 120-W laser versus transurethral resection of the prostate for benign prostatic hyperplasia: a systematic review with meta-analysis from 2002 to 2012. Eur Urol 62:315–323PubMedCrossRef

146.

Thomas AW, Cannon A, Bartlett E et al (2005) The natural history of lower urinary tract dysfunction in men: minimum 10-year urodynamic followup of transurethral resection of prostate for bladder outlet obstruction. J Urol 174:1887–1891PubMedCrossRef

147.

Tincello DG, Slack MC, Kenyon S et al (2011) Botulinum toxin-A for refractory detrusor overactivity in women: a 240 patient randomised placebo controlled trial. Eur Urol 10 (Suppl):191CrossRef

148.

Tkocz M, Prajsner A (2002) Comparison of long-term results of transurethral incision of the prostate with transurethral resection of the prostate, in patients with benign prostatic hypertrophy. Neurourol Urodyn 21:112–116PubMedCrossRef

149.

Tubaro A, Carter S, Hind A et al (2001) A prospective study of the safety and efficacy of suprapubic transvesical prostatectomy in patients with benign prostatic hyperplasia. J Urol 166:172–176PubMedCrossRef

150.

Tuhkanen K, Heino A, Aaltomaa S et al (2003) Long-term results of contact laser versus transurethral resection of the prostate in the treatment of benign prostatic hyperplasia with small or moderately enlarged prostates. Scand J Urol Nephrol 37:487–493PubMedCrossRef

151.

Tuhkanen K, Heino A, Alaopas M (1999) Hybrid laser treatment compared with transurethral resection of the prostate for symptomatic bladder outlet obstruction caused by a large benign prostate: a prospective, randomized trial with a 6-month follow-up. BJU Int 84:805–809PubMedCrossRef

152.

Van Melick HH, Van Venrooij GE, Eckhardt MD et al (2002) A randomized controlled trial comparing transurethral resection of the prostate, contact laser prostatectomy and electrovaporization in men with benign prostatic hyperplasia: urodynamic effects. J Urol 168:1058–1062CrossRef

153.

Varkarakis I, Kyriakakis Z, Delis A et al (2004) Long-term results of open transvesical prostatectomy from a contemporary series of patients. Urology 64:306–310PubMedCrossRef

154.

Varkarakis J, Bartsch G, Horninger W (2004) Long-term morbidity and mortality of transurethral prostatectomy: a 10-year follow-up. Prostate 58:248–251PubMedCrossRef

155.

Wagenlehner FM, Bescherer K, Wagenlehner C et al (2011) Urodynamic impact of acute urinary retention in patients with benign prostatic hyperplasia: a 2-year follow-up after transurethral resection of the prostate. Urol Int 86:73–79PubMedCrossRef

156.

Wagrell L, Schelin S, Nordling J et al (2002) Feedback microwave thermotherapy versus TURP for clinical BPH–a randomized controlled multicenter study. Urology 60:292–299PubMedCrossRef

157.

Westenberg A, Gilling P, Kennett K et al (2004) Holmium laser resection of the prostate versus transurethral resection of the prostate: results of a randomized trial with 4-year minimum long-term followup. J Urol 172:616–619PubMedCrossRef

158.

Wildt MJ de, Te Slaa E, Rosier PF et al (1995) Urodynamic results of laser treatment in patients with benign prostatic hyperplasia. Can outlet obstruction be relieved? J Urol 154:174–180PubMedCrossRef

159.

Wilson LC, Gilling PJ, Williams A et al (2006) A randomised trial comparing holmium laser enucleation versus transurethral resection in the treatment of prostates larger than 40 grams: results at 2 years. Eur Urol 50:569–573PubMedCrossRef

160.

Witjes WPJ, Robertson A, Rosier PF et al (1997) Urodynamic and clinical effects of noninvasive and minimally invasive treatments in elderly men with lower urinary tract symptoms stratified according to the grade of obstruction. Urology 50:55–61PubMedCrossRef

161.

Xia SJ, Zhuo J, Sun XW et al (2008) Thulium laser versus standard transurethral resection of the prostate: a randomized prospective trial. Eur Urol 53:382–389PubMedCrossRef

162.

Yang Q, Peters TJ, Donovan JL et al (2001) Transurethral incision compared with transurethral resection of the prostate for bladder outlet obstruction: a systematic review and meta-analysis of randomized controlled trials. J Urol 165:1526–1532PubMedCrossRef

163.

Zhang F, Shao Q, Herrmann TR et al (2012) Thulium laser versus holmium laser transurethral enucleation of the prostate: 18-month follow-up data of a single center. Urology 79:869–874PubMedCrossRef

Titel: S2e-Leitlinie der Deutschen Urologen
Instrumentelle Therapie des benignen Prostatasyndroms
verfasst von: PD Dr. Dr. T. Bschleipfer, FEBU
T. Bach
R. Berges
K. Dreikorn
C. Gratzke
S. Madersbacher
M.-S. Michel
R. Muschter
M. Oelke
O. Reich
C. Tschuschke
K. Höfner
Publikationsdatum: 01.02.2016
Verlag: Springer Berlin Heidelberg
Erschienen in: Die Urologie / Ausgabe 2/2016
Print ISSN: 2731-7064
Elektronische ISSN: 2731-7072
DOI: https://doi.org/10.1007/s00120-015-3983-0

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S2e-Leitlinie der Deutschen Urologen

Instrumentelle Therapie des benignen Prostatasyndroms

Zusammenfassung

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Mit dem Seitenschneider gegen das Reißverschluss-Malheur

Patrone im Penis bringt Urologen in Gefahr

15% bedauern gewählte Blasenkrebs-Therapie

Costims – das nächste heiße Ding in der Krebstherapie?

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