Skip to main content
Erschienen in: Aesthetic Plastic Surgery 3/2024

09.11.2023 | Review

Postoperative Scar Management Protocol for Asian Patients

verfasst von: Hargaven Singh Gill, Low O-Wern, Priya Tiwari, Gurveer Kaven Singh Gill, Chance Goh, Janet Hung, Jing Tzer Lee, Thiam Chye Lim, Jane Lim, Yan Lin Yap, Vigneswaran Nallathamby

Erschienen in: Aesthetic Plastic Surgery | Ausgabe 3/2024

Einloggen, um Zugang zu erhalten

Abstract

Background

Postoperative scar formation remains a morbidity for patients even with the advent of minimally invasive techniques. Furthermore, the significant difference between the Asian and Caucasian skin results in poorer postoperative scar outcomes in Asians, supporting the need for an evidence-based scar management protocol.

Methods

Following a literature review of the PubMed and the Cochrane databases over the past 10 years, we constructed a novel postoperative scar management protocol for the Asian skin, utilized in a Singaporean tertiary healthcare institution.

Results

We describe a timeline-based scar protocol from the point of skin closure to a minimum of 1 year of follow-up. We support the use of intraoperative botulinum toxin for selected high-risk individuals upon skin closure with a follow-up regimen in the postoperative setting. For recalcitrant keloids, we have described a multimodal therapy comprising elements of intralesional steroids, botulinum toxin, lasers, surgery, and radiotherapy.

Conclusions

A consolidated postoperative scar management protocol provides the necessary guidance for improved scar outcomes in the Asian skin. There is inherent potential in expanding the protocol to include post-traumatic and burn wounds or support other skin types including the Caucasian skin.

No Level Assigned

This journal requires that authors assign a level of evidence to each submission to which Evidence-Based Medicine rankings are applicable. This excludes Review Articles, Book Reviews, and manuscripts that concern Basic Science, Animal Studies, Cadaver Studies, and Experimental Studies. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.​springer.​com/​00266.
Literatur
1.
Zurück zum Zitat Soltani AM, Francis CS, Motamed A, Karatsonyi AL, Hammoudeh JA, Sanchez-Lara PA et al (2012) Hypertrophic scarring in cleft lip repair: a comparison of incidence among ethnic groups. Clin Epidemiol 4:187–191PubMedPubMedCentral Soltani AM, Francis CS, Motamed A, Karatsonyi AL, Hammoudeh JA, Sanchez-Lara PA et al (2012) Hypertrophic scarring in cleft lip repair: a comparison of incidence among ethnic groups. Clin Epidemiol 4:187–191PubMedPubMedCentral
2.
Zurück zum Zitat Ogawa R, Dohi T, Tosa M, Aoki M, Akaishi S (2021) The latest strategy for keloid and hypertrophic scar prevention and treatment: the nippon medical school (NMS) protocol. J Nippon Med Sch 88(1):2–9PubMedCrossRef Ogawa R, Dohi T, Tosa M, Aoki M, Akaishi S (2021) The latest strategy for keloid and hypertrophic scar prevention and treatment: the nippon medical school (NMS) protocol. J Nippon Med Sch 88(1):2–9PubMedCrossRef
4.
Zurück zum Zitat Potter DA, Veitch D, Johnston GA (2019) Scarring and wound healing. Br J Hosp Med Lond 80(11):C166–C171PubMedCrossRef Potter DA, Veitch D, Johnston GA (2019) Scarring and wound healing. Br J Hosp Med Lond 80(11):C166–C171PubMedCrossRef
5.
Zurück zum Zitat Dohi T, Padmanabhan J, Akaishi S, Than PA, Terashima M, Matsumoto NN et al (2019) The interplay of mechanical stress, strain, and stiffness at the keloid periphery correlates with increased caveolin-1/ROCK signaling and scar progression. Plast Reconstr Surg 144(1):58e–67ePubMedCrossRef Dohi T, Padmanabhan J, Akaishi S, Than PA, Terashima M, Matsumoto NN et al (2019) The interplay of mechanical stress, strain, and stiffness at the keloid periphery correlates with increased caveolin-1/ROCK signaling and scar progression. Plast Reconstr Surg 144(1):58e–67ePubMedCrossRef
6.
Zurück zum Zitat Quong WL, Kozai Y, Ogawa R (2017) A case of keloids complicated by castleman’s disease: interleukin-6 as a keloid risk factor. Plast Reconstr Surg Glob Open 5(5):e1336PubMedPubMedCentralCrossRef Quong WL, Kozai Y, Ogawa R (2017) A case of keloids complicated by castleman’s disease: interleukin-6 as a keloid risk factor. Plast Reconstr Surg Glob Open 5(5):e1336PubMedPubMedCentralCrossRef
7.
Zurück zum Zitat van der Veer WM, Bloemen MC, Ulrich MM, Molema G, van Zuijlen PP, Middelkoop E et al (2009) Potential cellular and molecular causes of hypertrophic scar formation. Burns 35(1):15–29PubMedCrossRef van der Veer WM, Bloemen MC, Ulrich MM, Molema G, van Zuijlen PP, Middelkoop E et al (2009) Potential cellular and molecular causes of hypertrophic scar formation. Burns 35(1):15–29PubMedCrossRef
8.
Zurück zum Zitat Ogawa R (2017) Keloid and hypertrophic scars are the result of chronic inflammation in the reticular dermis. Int J Mol Sci 18(3):526489ADSCrossRef Ogawa R (2017) Keloid and hypertrophic scars are the result of chronic inflammation in the reticular dermis. Int J Mol Sci 18(3):526489ADSCrossRef
9.
Zurück zum Zitat Ogawa R, Okai K, Tokumura F, Mori K, Ohmori Y, Huang C et al (2012) The relationship between skin stretching/contraction and pathologic scarring: the important role of mechanical forces in keloid generation. Wound Repair Regen 20(2):149–157PubMedCrossRef Ogawa R, Okai K, Tokumura F, Mori K, Ohmori Y, Huang C et al (2012) The relationship between skin stretching/contraction and pathologic scarring: the important role of mechanical forces in keloid generation. Wound Repair Regen 20(2):149–157PubMedCrossRef
10.
Zurück zum Zitat Harn HI, Ogawa R, Hsu CK, Hughes MW, Tang MJ, Chuong CM (2019) The tension biology of wound healing. Exp Dermatol 28(4):464–471PubMedCrossRef Harn HI, Ogawa R, Hsu CK, Hughes MW, Tang MJ, Chuong CM (2019) The tension biology of wound healing. Exp Dermatol 28(4):464–471PubMedCrossRef
11.
Zurück zum Zitat Park TH, Chang CH (2012) Keloid recurrence in pregnancy. Aesthet Plast Surg 36(5):1271–1272CrossRef Park TH, Chang CH (2012) Keloid recurrence in pregnancy. Aesthet Plast Surg 36(5):1271–1272CrossRef
13.
Zurück zum Zitat Arima J, Huang C, Rosner B, Akaishi S, Ogawa R (2015) Hypertension: a systemic key to understanding local keloid severity. Wound Repair Regen. 23(2):213–221PubMedCrossRef Arima J, Huang C, Rosner B, Akaishi S, Ogawa R (2015) Hypertension: a systemic key to understanding local keloid severity. Wound Repair Regen. 23(2):213–221PubMedCrossRef
14.
Zurück zum Zitat Dong X, Mao S, Wen H (2013) Upregulation of proinflammatory genes in skin lesions may be the cause of keloid formation (Review). Biomed Rep 1(6):833–836PubMedPubMedCentralCrossRef Dong X, Mao S, Wen H (2013) Upregulation of proinflammatory genes in skin lesions may be the cause of keloid formation (Review). Biomed Rep 1(6):833–836PubMedPubMedCentralCrossRef
15.
Zurück zum Zitat Marneros AG, Norris JE, Olsen BR, Reichenberger E (2001) Clinical genetics of familial keloids. Arch Dermatol 137(11):1429–1434PubMedCrossRef Marneros AG, Norris JE, Olsen BR, Reichenberger E (2001) Clinical genetics of familial keloids. Arch Dermatol 137(11):1429–1434PubMedCrossRef
16.
Zurück zum Zitat Nakashima M, Chung S, Takahashi A, Kamatani N, Kawaguchi T, Tsunoda T et al (2010) A genome-wide association study identifies four susceptibility loci for keloid in the Japanese population. Nat Genet 42(9):768–771PubMedCrossRef Nakashima M, Chung S, Takahashi A, Kamatani N, Kawaguchi T, Tsunoda T et al (2010) A genome-wide association study identifies four susceptibility loci for keloid in the Japanese population. Nat Genet 42(9):768–771PubMedCrossRef
17.
Zurück zum Zitat Ogawa R, Watanabe A, Than Naing B, Sasaki M, Fujita A, Akaishi S et al (2014) Associations between keloid severity and single-nucleotide polymorphisms: importance of rs8032158 as a biomarker of keloid severity. J Invest Dermatol 134(7):2041–2043PubMedCrossRef Ogawa R, Watanabe A, Than Naing B, Sasaki M, Fujita A, Akaishi S et al (2014) Associations between keloid severity and single-nucleotide polymorphisms: importance of rs8032158 as a biomarker of keloid severity. J Invest Dermatol 134(7):2041–2043PubMedCrossRef
18.
Zurück zum Zitat Fujita M, Yamamoto Y, Jiang JJ, Atsumi T, Tanaka Y, Ohki T et al (2019) NEDD4 Is involved in inflammation development during keloid formation. J Invest Dermatol 139(2):333–341PubMedCrossRef Fujita M, Yamamoto Y, Jiang JJ, Atsumi T, Tanaka Y, Ohki T et al (2019) NEDD4 Is involved in inflammation development during keloid formation. J Invest Dermatol 139(2):333–341PubMedCrossRef
19.
Zurück zum Zitat Abdu Allah AMK, Mohammed KI, Farag AGA, Hagag MM, Essam M, Tayel NR (2019) Interleukin-6 serum level and gene polymorphism in keloid patients. Cell Mol Biol Noisy Grand 65(5):43–48CrossRef Abdu Allah AMK, Mohammed KI, Farag AGA, Hagag MM, Essam M, Tayel NR (2019) Interleukin-6 serum level and gene polymorphism in keloid patients. Cell Mol Biol Noisy Grand 65(5):43–48CrossRef
20.
Zurück zum Zitat Chen Y, Gao JH, Liu XJ, Yan X, Song M (2006) Characteristics of occurrence for Han Chinese familial keloids. Burns 32(8):1052–1059PubMedCrossRef Chen Y, Gao JH, Liu XJ, Yan X, Song M (2006) Characteristics of occurrence for Han Chinese familial keloids. Burns 32(8):1052–1059PubMedCrossRef
21.
Zurück zum Zitat Hosalkar H, Greenberg J, Gaugler RL, Garg S, Dormans JP (2007) Abnormal scarring with keloid formation after osteochondroma excision in children with multiple hereditary exostoses. J Pediatr Orthop 27(3):333–337PubMedCrossRef Hosalkar H, Greenberg J, Gaugler RL, Garg S, Dormans JP (2007) Abnormal scarring with keloid formation after osteochondroma excision in children with multiple hereditary exostoses. J Pediatr Orthop 27(3):333–337PubMedCrossRef
22.
Zurück zum Zitat Miller MC, Nanchahal J (2005) Advances in the modulation of cutaneous wound healing and scarring. Bio Drugs 19(6):363–381 Miller MC, Nanchahal J (2005) Advances in the modulation of cutaneous wound healing and scarring. Bio Drugs 19(6):363–381
23.
Zurück zum Zitat Ogawa R, Miyashita T, Hyakusoku H, Akaishi S, Kuribayashi S, Tateno A (2007) Postoperative radiation protocol for keloids and hypertrophic scars: statistical analysis of 370 sites followed for over 18 months. Ann Plast Surg 59(6):688–691PubMedCrossRef Ogawa R, Miyashita T, Hyakusoku H, Akaishi S, Kuribayashi S, Tateno A (2007) Postoperative radiation protocol for keloids and hypertrophic scars: statistical analysis of 370 sites followed for over 18 months. Ann Plast Surg 59(6):688–691PubMedCrossRef
24.
Zurück zum Zitat Reiffel RS (1995) Prevention of hypertrophic scars by long-term paper tape application. Plast Reconstr Surg 96(7):1715–1718PubMedCrossRef Reiffel RS (1995) Prevention of hypertrophic scars by long-term paper tape application. Plast Reconstr Surg 96(7):1715–1718PubMedCrossRef
26.
28.
Zurück zum Zitat Monstrey S, Middelkoop E, Vranckx JJ, Bassetto F, Ziegler UE, Meaume S et al (2014) Updated scar management practical guidelines: non-invasive and invasive measures. J Plast Reconstr Aesthet Surg 67(8):1017–1025PubMedCrossRef Monstrey S, Middelkoop E, Vranckx JJ, Bassetto F, Ziegler UE, Meaume S et al (2014) Updated scar management practical guidelines: non-invasive and invasive measures. J Plast Reconstr Aesthet Surg 67(8):1017–1025PubMedCrossRef
29.
Zurück zum Zitat Kim S, Choi TH, Liu W, Ogawa R, Suh JS, Mustoe TA (2013) Update on scar management: guidelines for treating Asian patients. Plast Reconstr Surg 132(6):1580–1589PubMedCrossRef Kim S, Choi TH, Liu W, Ogawa R, Suh JS, Mustoe TA (2013) Update on scar management: guidelines for treating Asian patients. Plast Reconstr Surg 132(6):1580–1589PubMedCrossRef
30.
Zurück zum Zitat O’Brien L, Jones DJ (2013) Silicone gel sheeting for preventing and treating hypertrophic and keloid scars. Cochr Database Syst Rev 2013(9):003826 O’Brien L, Jones DJ (2013) Silicone gel sheeting for preventing and treating hypertrophic and keloid scars. Cochr Database Syst Rev 2013(9):003826
31.
Zurück zum Zitat Hsu KC, Luan CW, Tsai YW (2017) Review of silicone gel sheeting and silicone gel for the prevention of hypertrophic scars and keloids. Wounds 29(5):154–158PubMed Hsu KC, Luan CW, Tsai YW (2017) Review of silicone gel sheeting and silicone gel for the prevention of hypertrophic scars and keloids. Wounds 29(5):154–158PubMed
32.
Zurück zum Zitat Chan KY, Lau CL, Adeeb SM, Somasundaram S, Nasir-Zahari M (2005) A randomized, placebo-controlled, double-blind, prospective clinical trial of silicone gel in prevention of hypertrophic scar development in median sternotomy wound. Plast Reconstr Surg 116(4):1013–20PubMedCrossRef Chan KY, Lau CL, Adeeb SM, Somasundaram S, Nasir-Zahari M (2005) A randomized, placebo-controlled, double-blind, prospective clinical trial of silicone gel in prevention of hypertrophic scar development in median sternotomy wound. Plast Reconstr Surg 116(4):1013–20PubMedCrossRef
34.
Zurück zum Zitat Jourdan M, Madfes DC, Lima E, Tian Y, Seite S (2019) Skin care management for medical and aesthetic procedures to prevent scarring. Clin Cosmet Investig Dermatol 12:799–804PubMedPubMedCentralCrossRef Jourdan M, Madfes DC, Lima E, Tian Y, Seite S (2019) Skin care management for medical and aesthetic procedures to prevent scarring. Clin Cosmet Investig Dermatol 12:799–804PubMedPubMedCentralCrossRef
36.
Zurück zum Zitat Cho JW, Cho SY, Lee SR, Lee KS (2010) Onion extract and quercetin induce matrix metalloproteinase-1 in vitro and in vivo. Int J Mol Med 25(3):347–352MathSciNetPubMed Cho JW, Cho SY, Lee SR, Lee KS (2010) Onion extract and quercetin induce matrix metalloproteinase-1 in vitro and in vivo. Int J Mol Med 25(3):347–352MathSciNetPubMed
37.
Zurück zum Zitat Jenwitheesuk K, Surakunprapha P, Jenwitheesuk K, Kuptarnond C, Prathanee S, Intanoo W (2012) Role of silicone derivative plus onion extract gel in presternal hypertrophic scar protection: a prospective randomized, double blinded, controlled trial. Int Wound J 9(4):397–402PubMedCrossRef Jenwitheesuk K, Surakunprapha P, Jenwitheesuk K, Kuptarnond C, Prathanee S, Intanoo W (2012) Role of silicone derivative plus onion extract gel in presternal hypertrophic scar protection: a prospective randomized, double blinded, controlled trial. Int Wound J 9(4):397–402PubMedCrossRef
38.
Zurück zum Zitat Khansa I, Harrison B, Janis JE (2016) Evidence-based scar management: how to improve results with technique and technology. Plast Reconstr Surg 138(3 Suppl):165S-S178PubMedCrossRef Khansa I, Harrison B, Janis JE (2016) Evidence-based scar management: how to improve results with technique and technology. Plast Reconstr Surg 138(3 Suppl):165S-S178PubMedCrossRef
39.
Zurück zum Zitat Hosnuter M, Payasli C, Isikdemir A, Tekerekoglu B (2007) The effects of onion extract on hypertrophic and keloid scars. J Wound Care 16(6):251–254PubMedCrossRef Hosnuter M, Payasli C, Isikdemir A, Tekerekoglu B (2007) The effects of onion extract on hypertrophic and keloid scars. J Wound Care 16(6):251–254PubMedCrossRef
40.
Zurück zum Zitat Chung VQ, Kelley L, Marra D, Jiang SB (2006) Onion extract gel versus petrolatum emollient on new surgical scars: prospective double-blinded study. Dermatol Surg 32(2):193–197PubMed Chung VQ, Kelley L, Marra D, Jiang SB (2006) Onion extract gel versus petrolatum emollient on new surgical scars: prospective double-blinded study. Dermatol Surg 32(2):193–197PubMed
41.
Zurück zum Zitat Gold MH, Berman B, Clementoni MT, Gauglitz GG, Nahai F, Murcia C (2014) Updated international clinical recommendations on scar management: part 1–evaluating the evidence. Dermatol Surg 40(8):817–824PubMed Gold MH, Berman B, Clementoni MT, Gauglitz GG, Nahai F, Murcia C (2014) Updated international clinical recommendations on scar management: part 1–evaluating the evidence. Dermatol Surg 40(8):817–824PubMed
42.
Zurück zum Zitat Shin TM, Bordeaux JS (2012) The role of massage in scar management: a literature review. Dermatol Surg 38(3):414–423PubMedCrossRef Shin TM, Bordeaux JS (2012) The role of massage in scar management: a literature review. Dermatol Surg 38(3):414–423PubMedCrossRef
43.
Zurück zum Zitat Aarabi S, Bhatt KA, Shi Y, Paterno J, Chang EI, Loh SA et al (2007) Mechanical load initiates hypertrophic scar formation through decreased cellular apoptosis. Faseb J 21(12):3250–3261PubMedCrossRef Aarabi S, Bhatt KA, Shi Y, Paterno J, Chang EI, Loh SA et al (2007) Mechanical load initiates hypertrophic scar formation through decreased cellular apoptosis. Faseb J 21(12):3250–3261PubMedCrossRef
44.
Zurück zum Zitat Berman B, Viera MH, Amini S, Huo R, Jones IS (2008) Prevention and management of hypertrophic scars and keloids after burns in children. J Craniofac Surg 19(4):989–1006PubMedCrossRef Berman B, Viera MH, Amini S, Huo R, Jones IS (2008) Prevention and management of hypertrophic scars and keloids after burns in children. J Craniofac Surg 19(4):989–1006PubMedCrossRef
45.
Zurück zum Zitat Ai JW, Liu JT, Pei SD, Liu Y, Li DS, Lin HM et al (2017) The effectiveness of pressure therapy (15–25 mmHg) for hypertrophic burn scars: a systematic review and meta-analysis. Sci Rep 7:40185ADSPubMedPubMedCentralCrossRef Ai JW, Liu JT, Pei SD, Liu Y, Li DS, Lin HM et al (2017) The effectiveness of pressure therapy (15–25 mmHg) for hypertrophic burn scars: a systematic review and meta-analysis. Sci Rep 7:40185ADSPubMedPubMedCentralCrossRef
46.
Zurück zum Zitat Macintyre L, Baird M (2006) Pressure garments for use in the treatment of hypertrophic scars—a review of the problems associated with their use. Burns 32(1):10–15PubMedCrossRef Macintyre L, Baird M (2006) Pressure garments for use in the treatment of hypertrophic scars—a review of the problems associated with their use. Burns 32(1):10–15PubMedCrossRef
47.
Zurück zum Zitat Ketchum LD, Smith J, Robinson DW, Masters FW (1966) The treatment of hypertrophic scar, keloid and scar contracture by triamcinolone acetonide. Plast Reconstr Surg 38(3):209–218PubMedCrossRef Ketchum LD, Smith J, Robinson DW, Masters FW (1966) The treatment of hypertrophic scar, keloid and scar contracture by triamcinolone acetonide. Plast Reconstr Surg 38(3):209–218PubMedCrossRef
48.
Zurück zum Zitat Morelli Coppola M, Salzillo R, Segreto F, Persichetti P (2018) Triamcinolone acetonide intralesional injection for the treatment of keloid scars: patient selection and perspectives. Clin Cosmet Investig Dermatol 11:387–396PubMedPubMedCentralCrossRef Morelli Coppola M, Salzillo R, Segreto F, Persichetti P (2018) Triamcinolone acetonide intralesional injection for the treatment of keloid scars: patient selection and perspectives. Clin Cosmet Investig Dermatol 11:387–396PubMedPubMedCentralCrossRef
49.
Zurück zum Zitat Roques C, Teot L (2008) The use of corticosteroids to treat keloids: a review. Int J Low Extrem Wounds 7(3):137–145PubMedCrossRef Roques C, Teot L (2008) The use of corticosteroids to treat keloids: a review. Int J Low Extrem Wounds 7(3):137–145PubMedCrossRef
50.
Zurück zum Zitat Tan CWX, Tan WD, Srivastava R, Yow AP, Wong DWK, Tey HL (2019) Dissolving triamcinolone-embedded microneedles for the treatment of keloids: a single-blinded intra-individual controlled clinical trial. Dermatol Ther Heidelb 9(3):601–611PubMedPubMedCentralCrossRef Tan CWX, Tan WD, Srivastava R, Yow AP, Wong DWK, Tey HL (2019) Dissolving triamcinolone-embedded microneedles for the treatment of keloids: a single-blinded intra-individual controlled clinical trial. Dermatol Ther Heidelb 9(3):601–611PubMedPubMedCentralCrossRef
51.
Zurück zum Zitat Kasyanju Carrero LM, Ma WW, Liu HF, Yin XF, Zhou BR (2019) Botulinum toxin type A for the treatment and prevention of hypertrophic scars and keloids: Updated review. J Cosmet Dermatol 18(1):10–15PubMedCrossRef Kasyanju Carrero LM, Ma WW, Liu HF, Yin XF, Zhou BR (2019) Botulinum toxin type A for the treatment and prevention of hypertrophic scars and keloids: Updated review. J Cosmet Dermatol 18(1):10–15PubMedCrossRef
52.
Zurück zum Zitat Li YH, Yang J, Liu JQ, Xie ST, Zhang YJ, Zhang W et al (2018) A randomized, placebo-controlled, double-blind, prospective clinical trial of botulinum toxin type A in prevention of hypertrophic scar development in median sternotomy wound. Aesthetic Plast Surg 42(5):1364–1369PubMedCrossRef Li YH, Yang J, Liu JQ, Xie ST, Zhang YJ, Zhang W et al (2018) A randomized, placebo-controlled, double-blind, prospective clinical trial of botulinum toxin type A in prevention of hypertrophic scar development in median sternotomy wound. Aesthetic Plast Surg 42(5):1364–1369PubMedCrossRef
53.
Zurück zum Zitat Huang RL, Ho CK, Tremp M, Xie Y, Li Q, Zan T (2019) Early postoperative application of botulinum toxin type A prevents hypertrophic scarring after epicanthoplasty: a split-face, double-blind. Randomized Trial Plast Reconstr Surg 144(4):835–844PubMedCrossRef Huang RL, Ho CK, Tremp M, Xie Y, Li Q, Zan T (2019) Early postoperative application of botulinum toxin type A prevents hypertrophic scarring after epicanthoplasty: a split-face, double-blind. Randomized Trial Plast Reconstr Surg 144(4):835–844PubMedCrossRef
54.
Zurück zum Zitat Bi M, Sun P, Li D, Dong Z, Chen Z (2019) Intralesional injection of botulinum toxin type A compared with intralesional injection of corticosteroid for the treatment of hypertrophic scar and keloid: a systematic review and meta-analysis. Med Sci Monit 25:2950–2958PubMedPubMedCentralCrossRef Bi M, Sun P, Li D, Dong Z, Chen Z (2019) Intralesional injection of botulinum toxin type A compared with intralesional injection of corticosteroid for the treatment of hypertrophic scar and keloid: a systematic review and meta-analysis. Med Sci Monit 25:2950–2958PubMedPubMedCentralCrossRef
55.
Zurück zum Zitat Wu WTL (2011) Skin resurfacing with Microbotox and the treatment of keloids. In: Benedetto AV (ed) Botulinum toxins in clinical aesthetic practice, 2nd edn. Informa Health Care, pp 190–205 Wu WTL (2011) Skin resurfacing with Microbotox and the treatment of keloids. In: Benedetto AV (ed) Botulinum toxins in clinical aesthetic practice, 2nd edn. Informa Health Care, pp 190–205
56.
Zurück zum Zitat Khoury JG, Saluja R, Goldman MP (2008) The effect of botulinum toxin type A on full-face intense pulsed light treatment: a randomized, double-blind, split-face study. Dermatol Surg 34(8):1062–1069PubMed Khoury JG, Saluja R, Goldman MP (2008) The effect of botulinum toxin type A on full-face intense pulsed light treatment: a randomized, double-blind, split-face study. Dermatol Surg 34(8):1062–1069PubMed
57.
Zurück zum Zitat Gamil HD, Khattab FM, El Fawal MM, Eldeeb SE (2020) Comparison of intralesional triamcinolone acetonide, botulinum toxin type A, and their combination for the treatment of keloid lesions. J Dermatol Treat 31(5):535–544CrossRef Gamil HD, Khattab FM, El Fawal MM, Eldeeb SE (2020) Comparison of intralesional triamcinolone acetonide, botulinum toxin type A, and their combination for the treatment of keloid lesions. J Dermatol Treat 31(5):535–544CrossRef
58.
Zurück zum Zitat Bouzari N, Davis SC, Nouri K (2007) Laser treatment of keloids and hypertrophic scars. Int J Dermatol 46(1):80–88PubMedCrossRef Bouzari N, Davis SC, Nouri K (2007) Laser treatment of keloids and hypertrophic scars. Int J Dermatol 46(1):80–88PubMedCrossRef
59.
Zurück zum Zitat Al-Mohamady Ael S, Ibrahim SM, Muhammad MM (2016) Pulsed dye laser versus long-pulsed Nd:YAG laser in the treatment of hypertrophic scars and keloid: a comparative randomized split-scar trial. J Cosmet Laser Ther 18(4):208–212CrossRef Al-Mohamady Ael S, Ibrahim SM, Muhammad MM (2016) Pulsed dye laser versus long-pulsed Nd:YAG laser in the treatment of hypertrophic scars and keloid: a comparative randomized split-scar trial. J Cosmet Laser Ther 18(4):208–212CrossRef
60.
Zurück zum Zitat Kono T, Ercocen AR, Nakazawa H, Honda T, Hayashi N, Nozaki M (2003) The flashlamp-pumped pulsed dye laser (585 nm) treatment of hypertrophic scars in Asians. Ann Plast Surg 51(4):366–371PubMedCrossRef Kono T, Ercocen AR, Nakazawa H, Honda T, Hayashi N, Nozaki M (2003) The flashlamp-pumped pulsed dye laser (585 nm) treatment of hypertrophic scars in Asians. Ann Plast Surg 51(4):366–371PubMedCrossRef
61.
Zurück zum Zitat Jin R, Huang X, Li H, Yuan Y, Li B, Cheng C et al (2013) Laser therapy for prevention and treatment of pathologic excessive scars. Plast Reconstr Surg 132(6):1747–1758PubMedCrossRef Jin R, Huang X, Li H, Yuan Y, Li B, Cheng C et al (2013) Laser therapy for prevention and treatment of pathologic excessive scars. Plast Reconstr Surg 132(6):1747–1758PubMedCrossRef
62.
Zurück zum Zitat Koike S, Akaishi S, Nagashima Y, Dohi T, Hyakusoku H, Ogawa R (2014) Nd:YAG laser treatment for keloids and hypertrophic scars: an analysis of 102 cases. Plast Reconstr Surg Glob Open 2(12):e272PubMedCrossRef Koike S, Akaishi S, Nagashima Y, Dohi T, Hyakusoku H, Ogawa R (2014) Nd:YAG laser treatment for keloids and hypertrophic scars: an analysis of 102 cases. Plast Reconstr Surg Glob Open 2(12):e272PubMedCrossRef
63.
Zurück zum Zitat Tsai CH, Kao HK, Akaishi S, An-Jou Lin J, Ogawa R (2020) Combination of 1,064-nm neodymium-doped yttrium aluminum garnet laser and steroid tape decreases the total treatment time of hypertrophic scars: an analysis of 40 cases of cesarean-section scars. Dermatol Surg 46(8):1062–1067PubMedCrossRef Tsai CH, Kao HK, Akaishi S, An-Jou Lin J, Ogawa R (2020) Combination of 1,064-nm neodymium-doped yttrium aluminum garnet laser and steroid tape decreases the total treatment time of hypertrophic scars: an analysis of 40 cases of cesarean-section scars. Dermatol Surg 46(8):1062–1067PubMedCrossRef
64.
Zurück zum Zitat Khatri KA, Mahoney DL, McCartney MJ (2011) Laser scar revision: a review. J Cosmet Laser Ther 13(2):54–62PubMedCrossRef Khatri KA, Mahoney DL, McCartney MJ (2011) Laser scar revision: a review. J Cosmet Laser Ther 13(2):54–62PubMedCrossRef
65.
Zurück zum Zitat Seegenschmiedt MH, Micke O, Niewald M, Mucke R, Eich HT, Kriz J et al (2015) Degro guidelines for the radiotherapy of non-malignant disorders: part III: hyperproliferative disorders. Strahlenther Onkol 191(7):541–548PubMedCrossRef Seegenschmiedt MH, Micke O, Niewald M, Mucke R, Eich HT, Kriz J et al (2015) Degro guidelines for the radiotherapy of non-malignant disorders: part III: hyperproliferative disorders. Strahlenther Onkol 191(7):541–548PubMedCrossRef
66.
Zurück zum Zitat Ogawa R, Tosa M, Dohi T, Akaishi S, Kuribayashi S (2019) Surgical excision and postoperative radiotherapy for keloids. Scars Burn Heal. 5:2059513119891113PubMedPubMedCentral Ogawa R, Tosa M, Dohi T, Akaishi S, Kuribayashi S (2019) Surgical excision and postoperative radiotherapy for keloids. Scars Burn Heal. 5:2059513119891113PubMedPubMedCentral
67.
Zurück zum Zitat Ogawa R (2022) The most current algorithms for the treatment and prevention of hypertrophic scars and keloids: a 2020 update of the algorithms published 10 years ago. Plast Reconstr Surg 149(1):79e–94ePubMedCrossRef Ogawa R (2022) The most current algorithms for the treatment and prevention of hypertrophic scars and keloids: a 2020 update of the algorithms published 10 years ago. Plast Reconstr Surg 149(1):79e–94ePubMedCrossRef
68.
Zurück zum Zitat Arima J, Dohi T, Kuribayashi S, Akaishi S, Ogawa R (2019) Z-plasty and postoperative radiotherapy for anterior chest wall keloids: an analysis of 141 patients. Plast Reconstr Surg Glob Open 7(3):e2177PubMedPubMedCentralCrossRef Arima J, Dohi T, Kuribayashi S, Akaishi S, Ogawa R (2019) Z-plasty and postoperative radiotherapy for anterior chest wall keloids: an analysis of 141 patients. Plast Reconstr Surg Glob Open 7(3):e2177PubMedPubMedCentralCrossRef
69.
Zurück zum Zitat Dohi T, Kuribayashi S, Tosa M, Aoki M, Akaishi S, Ogawa R (2019) Z-plasty and postoperative radiotherapy for upper-arm keloids: an analysis of 38 patients. Plast Reconstr Surg Glob Open 7(11):e2496PubMedPubMedCentralCrossRef Dohi T, Kuribayashi S, Tosa M, Aoki M, Akaishi S, Ogawa R (2019) Z-plasty and postoperative radiotherapy for upper-arm keloids: an analysis of 38 patients. Plast Reconstr Surg Glob Open 7(11):e2496PubMedPubMedCentralCrossRef
70.
Zurück zum Zitat Al Aradi IK, Alawadhi SA, Alkhawaja FA, Alaradi I (2013) Earlobe keloids: a pilot study of the efficacy of keloidectomy with core fillet flap and adjuvant intralesional corticosteroids. Dermatol Surg 39(10):1514–1519PubMedCrossRef Al Aradi IK, Alawadhi SA, Alkhawaja FA, Alaradi I (2013) Earlobe keloids: a pilot study of the efficacy of keloidectomy with core fillet flap and adjuvant intralesional corticosteroids. Dermatol Surg 39(10):1514–1519PubMedCrossRef
71.
Zurück zum Zitat Akita S, Akino K, Yakabe A, Imaizumi T, Tanaka K, Anraku K et al (2007) Combined surgical excision and radiation therapy for keloid treatment. J Craniofac Surg 18(5):1164–1169PubMedCrossRef Akita S, Akino K, Yakabe A, Imaizumi T, Tanaka K, Anraku K et al (2007) Combined surgical excision and radiation therapy for keloid treatment. J Craniofac Surg 18(5):1164–1169PubMedCrossRef
73.
Zurück zum Zitat Alhady SM, Sivanantharajah K (1969) Keloids in various races. A review of 175 cases. Plast Reconstr Surg 44(6):564–6PubMedCrossRef Alhady SM, Sivanantharajah K (1969) Keloids in various races. A review of 175 cases. Plast Reconstr Surg 44(6):564–6PubMedCrossRef
Metadaten
Titel
Postoperative Scar Management Protocol for Asian Patients
verfasst von
Hargaven Singh Gill
Low O-Wern
Priya Tiwari
Gurveer Kaven Singh Gill
Chance Goh
Janet Hung
Jing Tzer Lee
Thiam Chye Lim
Jane Lim
Yan Lin Yap
Vigneswaran Nallathamby
Publikationsdatum
09.11.2023
Verlag
Springer US
Erschienen in
Aesthetic Plastic Surgery / Ausgabe 3/2024
Print ISSN: 0364-216X
Elektronische ISSN: 1432-5241
DOI
https://doi.org/10.1007/s00266-023-03696-2

Weitere Artikel der Ausgabe 3/2024

Aesthetic Plastic Surgery 3/2024 Zur Ausgabe

Häusliche Gewalt in der orthopädischen Notaufnahme oft nicht erkannt

28.05.2024 Häusliche Gewalt Nachrichten

In der Notaufnahme wird die Chance, Opfer von häuslicher Gewalt zu identifizieren, von Orthopäden und Orthopädinnen offenbar zu wenig genutzt. Darauf deuten die Ergebnisse einer Fragebogenstudie an der Sahlgrenska-Universität in Schweden hin.

Fehlerkultur in der Medizin – Offenheit zählt!

28.05.2024 Fehlerkultur Podcast

Darüber reden und aus Fehlern lernen, sollte das Motto in der Medizin lauten. Und zwar nicht nur im Sinne der Patientensicherheit. Eine negative Fehlerkultur kann auch die Behandelnden ernsthaft krank machen, warnt Prof. Dr. Reinhard Strametz. Ein Plädoyer und ein Leitfaden für den offenen Umgang mit kritischen Ereignissen in Medizin und Pflege.

Mehr Frauen im OP – weniger postoperative Komplikationen

21.05.2024 Allgemeine Chirurgie Nachrichten

Ein Frauenanteil von mindestens einem Drittel im ärztlichen Op.-Team war in einer großen retrospektiven Studie aus Kanada mit einer signifikanten Reduktion der postoperativen Morbidität assoziiert.

TAVI versus Klappenchirurgie: Neue Vergleichsstudie sorgt für Erstaunen

21.05.2024 TAVI Nachrichten

Bei schwerer Aortenstenose und obstruktiver KHK empfehlen die Leitlinien derzeit eine chirurgische Kombi-Behandlung aus Klappenersatz plus Bypass-OP. Diese Empfehlung wird allerdings jetzt durch eine aktuelle Studie infrage gestellt – mit überraschender Deutlichkeit.

Update Chirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

S3-Leitlinie „Diagnostik und Therapie des Karpaltunnelsyndroms“

Karpaltunnelsyndrom BDC Leitlinien Webinare
CME: 2 Punkte

Das Karpaltunnelsyndrom ist die häufigste Kompressionsneuropathie peripherer Nerven. Obwohl die Anamnese mit dem nächtlichen Einschlafen der Hand (Brachialgia parästhetica nocturna) sehr typisch ist, ist eine klinisch-neurologische Untersuchung und Elektroneurografie in manchen Fällen auch eine Neurosonografie erforderlich. Im Anfangsstadium sind konservative Maßnahmen (Handgelenksschiene, Ergotherapie) empfehlenswert. Bei nicht Ansprechen der konservativen Therapie oder Auftreten von neurologischen Ausfällen ist eine Dekompression des N. medianus am Karpaltunnel indiziert.

Prof. Dr. med. Gregor Antoniadis
Berufsverband der Deutschen Chirurgie e.V.

S2e-Leitlinie „Distale Radiusfraktur“

Radiusfraktur BDC Leitlinien Webinare
CME: 2 Punkte

Das Webinar beschäftigt sich mit Fragen und Antworten zu Diagnostik und Klassifikation sowie Möglichkeiten des Ausschlusses von Zusatzverletzungen. Die Referenten erläutern, welche Frakturen konservativ behandelt werden können und wie. Das Webinar beantwortet die Frage nach aktuellen operativen Therapiekonzepten: Welcher Zugang, welches Osteosynthesematerial? Auf was muss bei der Nachbehandlung der distalen Radiusfraktur geachtet werden?

PD Dr. med. Oliver Pieske
Dr. med. Benjamin Meyknecht
Berufsverband der Deutschen Chirurgie e.V.

S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“

Appendizitis BDC Leitlinien Webinare
CME: 2 Punkte

Inhalte des Webinars zur S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“ sind die Darstellung des Projektes und des Erstellungswegs zur S1-Leitlinie, die Erläuterung der klinischen Relevanz der Klassifikation EAES 2015, die wissenschaftliche Begründung der wichtigsten Empfehlungen und die Darstellung stadiengerechter Therapieoptionen.

Dr. med. Mihailo Andric
Berufsverband der Deutschen Chirurgie e.V.