Erschienen in:
10.03.2017 | What's New in Intensive Care
Mechanism of ICU-acquired weakness: skeletal muscle loss in critical illness
verfasst von:
Jane Batt, Margaret Herridge, Claudia dos Santos
Erschienen in:
Intensive Care Medicine
|
Ausgabe 12/2017
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Excerpt
Survival from critical illness is often the beginning of an arduous journey of recovery from physical disability related to critical illness polyneuropathy (CIP) and myopathy (CIM) that individually, or together, comprise ICU-acquired weakness (ICUAW) [
1]. Muscle atrophy, which occurs rapidly in the critically ill patient, is a priority research focus in critical care. This discussion will highlight current knowledge of the cellular and molecular mechanisms implicated in muscle loss. …