International Journal of Clinical Pharmacy OnlineFirst articles

Open Access 01.06.2024 | Research Article

Protocols versus practice: unravelling clinical checking variations in community pharmacies in England—a multi-method study

Pharmacists deviate from SOPs during clinical checks, and these deviations were observed in controlled, quiet conditions, suggesting a cultural inclination to depart from standard procedures despite the absence of external influences. The practice …

verfasst von:: Ali Elgebli, Jason Hall, Denham L. Phipps

PDF-Version jetzt herunterladen Zum Volltext

01.06.2024 | Research Article

Medication Literacy Test for Older Adults: psychometric analysis and standardization of the new instrument

The TELUMI may be used for pharmacoepidemiological research, allowing more accurate measures of medication literacy in older adults, to understand its relationship with adherence and self-efficacy. The TELUMI can be used in pharmaceutical clinical …

verfasst von:: Laís Lessa Neiva Pantuzza, Adriano Max Moreira Reis, Stephanie Ferreira Botelho, Ana Luiza Pereira da Rocha, Maria Auxiliadora Parreiras Martins, Mariana Martins Gonzaga do Nascimento, Liliana Batista Vieira, Ronara Camila de Souza Groia Veloso, Elizabeth do Nascimento

30.05.2024 | Research Article

Impact of intra-patient variability of tacrolimus on allograft function and CD4 + /CD8 + ratio in kidney transplant recipients: a retrospective single-center study

Tacrolimus intra-patient variation (IPV) is significantly correlated with kidney function in transplant recipients, as evidenced by its strong association with the serum creatinine clearance rate and the estimated glomerular filtration rate. High …

verfasst von:: Xuebin Wang, Zhengyue Liu, Jingxia Chen, Yuhui Chai, Xueqing Shao, Wenmin Xie, Kaile Zheng, Jia You, Zhuo Wang, Meiqing Feng

Open Access 30.05.2024 | Research Article

Economic cost-benefit analysis of person-centred medicines reviews by general practice pharmacists

Integration of pharmacists into general practice to deliver structured person-centred medicines reviews is economically dominant, delivering a return on investment far above expenditure on service delivery. General practice pharmacist-led medicines …

verfasst von:: Cian O’Mahony, Kieran Dalton, Leon O’Hagan, Kevin D. Murphy, Clare Kinahan, Emma Coyle, Laura J. Sahm, Stephen Byrne, Ciara Kirke

PDF-Version jetzt herunterladen Zum Volltext

30.05.2024 | Research Article

Economic evaluation of camrelizumab plus rivoceranib versus sorafenib as first-line therapy for unresectable hepatocellular carcinoma in the United States and China

Compared with sorafenib, camrelizumab plus rivoceranib is suggested for the unresectable hepatocellular carcinoma due to its efficacy and economic sustainability for the Chinese healthcare system. The price simulation was conducted involving …

verfasst von:: Jingxuan Wei, Kai Xu, Yingtao Lin, Qiang Liu, Chongchong Zhou, Pei Zhang, Rui Ma, Mengdie Zhang, Lingli Zhang, Xin Li

28.05.2024 | Research Article

Measuring the impact of pharmaceutical care bundle delivery on patient outcomes: an observational study

This study measures the extent of individual and bundled pharmaceutical care for patients in a real-world context and demonstrates reductions in unplanned re-admission within 30 days at hospitals where bundled activities are delivered to a higher …

verfasst von:: Martin Luke Canning, Ross McDougall, Stephanie Yerkovich, Michael Barras, Ian Coombes, Clair Sullivan, Karen Whitfield

16.05.2024 | Research Article

Developing a machine learning model for predicting venlafaxine active moiety concentration: a retrospective study using real-world evidence

We found five influential variables that affect venlafaxine concentration, which were venlafaxine daily dose, sex, age, hyperlipidemia, and adenosine deaminase. To the best of our knowledge, this is the first machine-learning model to predict the …

verfasst von:: Luyao Chang, Xin Hao, Jing Yu, Jinyuan Zhang, Yimeng Liu, Xuxiao Ye, Ze Yu, Fei Gao, Xiaolu Pang, Chunhua Zhou

Open Access 16.05.2024 | Research Article

Development and Delphi consensus validation of the Medication-Related Fall screening and scoring tool

The MRF tool is an informative tool that can be used in different healthcare settings to evaluate and optimise medications to reduce falls and fall-related negative outcomes. The MRF tool can help to standardise clinical practice and guidelines on …

verfasst von:: Dima Saeed, Gillian Carter, Ruth Miller, Carmel Darcy, Karen Miller, Kevin Madden, Hilary McKee, Jayne Agnew, Paula Crawford, Carole Parsons

PDF-Version jetzt herunterladen Zum Volltext

Open Access 16.05.2024 | Research Article

Preliminary feasibility assessment of a targeted, pharmacist-led intervention for older adults with polypharmacy: a mixed-methods study

A pharmacist-led intervention was evaluated in a primary care setting, demonstrating its feasibility. The findings suggest a potentially promising strategy to address problematic polypharmacy in older adults, paving the way for a comprehensive …

verfasst von:: Lisheng Liu, Bernadette Brokenshire, Deborah Davies, Jeff Harrison

PDF-Version jetzt herunterladen Zum Volltext

11.05.2024 | Research Article

Personalized venlafaxine dose prediction using artificial intelligence technology: a retrospective analysis based on real-world data

This study marks the first use of artificial intelligence techniques to estimate venlafaxine doses for patients with depression, providing valuable information for clinical drug recommendations. The model demonstrated robust prediction performance …

verfasst von:: Yimeng Liu, Ze Yu, Xuxiao Ye, Jinyuan Zhang, Xin Hao, Fei Gao, Jing Yu, Chunhua Zhou

11.05.2024 | Research Article

A randomised, crossover trial exploring the patient perspective and effectiveness of biosimilar adalimumab transition: IBD reference and biosimilar adalimumab cross over study (iBaSS)

Biosimilar medicines are critical to ensuring sustainability of healthcare systems, improving access to treatment and fostering innovation. Patient satisfaction is critical to the successful implementation of these medicines and a better …

verfasst von:: David Young, Clare Harris, Sohail Rahmany, Inês Iria, João Gonçalves, Janet Addison, Justin Harvey, Sue Latter, Fraser Cummings

11.05.2024 | Review Article

Medication errors in emergency departments: a systematic review and meta-analysis of prevalence and severity

Medication errors in emergency departments may contribute to adverse health outcomes, longer hospital stays and increased healthcare costs. Efforts to address these errors are essential for enhancing patient care and alleviating healthcare system …

verfasst von:: Phuong Thi Lan Nguyen, Thu Anh Thi Phan, Van Bich Ngoc Vo, Nhi T. N. Ngo, Ha Thi Nguyen, Toi Lam Phung, Mai Thi Tuyet Kieu, Thao Huong Nguyen, Khanh N. C. Duong

10.05.2024 | Research Article

Optimisation of medication reconciliation using queueing theory: a computer experiment

Queueing theory, the mathematical study of waiting lines, or queues, can be used in the safe environment of a computer experiment to test various interventions to optimise the medication reconciliation process in the hospital pharmacy. Strategic …

verfasst von:: W. J. Kruik-Kollöffel, G. A. W. Moltman, M. D. Wu, A. Braaksma, F. Karapinar, R. J. Boucherie

Open Access 10.05.2024 | Research Article

Investigating practice integration of independent prescribing by community pharmacists using normalization process theory: a cross-sectional survey

Independent prescribing (IP) by pharmacists exists in several countries and can impact positively patient services but its integration into community pharmacy (CP) has not been extensively investigated. The use of theory positively impacts the …

verfasst von:: L. Karim, T. McIntosh, T. Jebara, D. Pfleger, A. Osprey, S. Cunningham

PDF-Version jetzt herunterladen Zum Volltext

10.05.2024 | Research Article

Global trends in pharmacovigilance-related events: a 30-year analysis from the 2019 global burden of disease study

A key challenge lies in evaluating the effectiveness of pharmacovigilance policies on patient safety across nations with diverse developmental levels. Accurately assessing this impact is crucial for enhancing global patient safety standards. The …

verfasst von:: Shuzhi Lin, Shuang Lei, Wei Liu, Xiaoying Zhu, Lin Yin, Qian Liu, Bianling Feng

Open Access 05.05.2024 | Review Article

The influence of patients’ beliefs about medicines and the relationship with suboptimal medicine use in community-dwelling older adults: a systematic review of quantitative studies

The relationship between medication beliefs and adherence is multifaceted and can vary based on patient populations and other contextual factors. Stronger beliefs in the necessity of medications and reduced concerns appear to positively influence …

verfasst von:: Eman Rafhi, Malath Al-Juhaishi, Ieva Stupans, Julie E. Stevens, Joon Soo Park, Kate N. Wang

PDF-Version jetzt herunterladen Zum Volltext

05.05.2024 | Short Research Report

Prevalence and trends in polypharmacy and excessive polypharmacy: a retrospective national database analysis (2012–2021)

National claims data are a valuable tool to monitor prevalence and temporal trends of polypharmacy and excessive polypharmacy, enabling proactive healthcare management and policy development. Regional disparities in medication usage in Belgium …

verfasst von:: Lorenz Van der Linden, Jos Tournoy

Open Access 25.04.2024 | Research Article

The role of community pharmacists and pharmacies in physical activity promotion: an interdisciplinary e-Delphi study

Consensual interprofessional perspectives on the role of community pharmacists and pharmacies on physical activity promotion offer a foundation for the development of policies and guidelines more likely to gain support from healthcare …

verfasst von:: Ruben Viegas, Mara Pereira Guerreiro, Filipa Duarte-Ramos, Romeu Mendes, Filipa Alves da Costa

PDF-Version jetzt herunterladen Zum Volltext

25.04.2024 | Review Article

Intraclass comparison of inhaled corticosteroids for the risk of pneumonia in chronic obstructive pulmonary airway disorder: a network meta-analysis and meta-regression

Clinicians should consider dosage, body mass index, and exacerbation history while prescribing inhalational corticosteroids to mitigate the risk of pneumonia. Pharmacists should educate patients about the risk of pneumonia while dispensing …

verfasst von:: Kannan Sridharan, Gowri Sivaramakrishnan

20.04.2024 | Research Article

Cost-effectiveness analysis of fruquintinib in Chinese patients with refractory metastatic colorectal cancer

Reevaluation of Fruquintinib's Cost-Effectiveness: The study’s findings suggest that fruquintinib, following price reductions and policy changes in China, should be reassessed for its cost-effectiveness in treating refractory metastatic colorectal …

verfasst von:: Zijia Huang, Lingyan Zhou, Hanrui Zheng, Mei Zhan

Live-Webinar "Urologie und Sexualmedizin in der Praxis"

Springer Medizin