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Japanese Journal of Ophthalmology OnlineFirst articles

Open Access 30.05.2024 | Clinical Investigation

Comparative features of superior versus inferior hemisphere microvasculature dropout in open-angle glaucoma

Glaucoma is the second most common cause of blindness worldwide [ 1 , 2 ]. In general, it is considered that high intraocular pressure (IOP) leads to damage to the lamina cribrosa where the optic nerve runs through it. Therefore, therapies aimed at …

verfasst von:
Naoki Takahashi, Kazuko Omodaka, Tsutomu Kikawa, Takahiro Ninomiya, Naoki Kiyota, Satoru Tsuda, Toru Nakazawa

25.05.2024 | Clinical Investigation

Efficacy of a wearable night-vision aid in patients with concentric peripheral visual field loss: a randomized, crossover trial

Patients with retinitis pigmentosa (RP) or advanced glaucoma experience not only night blindness, but also concentric peripheral visual field loss. Owing to concentric peripheral visual field loss, these patients have a poorer quality of life …

verfasst von:
Go Mawatari, Shogo Hiwatashi, Tsubasa Motani, Saori Nagatomo, Eri Ando, Toshiki Kuwahata, Masataka Ishizu, Yasuhiro Ikeda

Open Access 25.05.2024 | Laboratory Investigation

Trans-eyelid distribution of epinastine to the conjunctiva following eyelid application in rabbits

Topical administration of anti-allergic eye drops is the first-line treatment for treating allergic conjunctivitis, one of the common inflammatory diseases in the conjunctiva causing ocular itching, redness, and swelling [ 1 , 2 ]. However, eye …

verfasst von:
Takaharu Mochizuki, Tatsuya Hata, Naoto Mori, Takashi Yamazaki, Takahisa Noto, Hidetoshi Mano

25.05.2024 | Clinical Investigation

Efficacy of 3% diquafosol long-acting eye drops in dry eye patients treated for three months

Dry eye disease (DE) is a complex ocular condition characterized by an unstable tear film, leading to various discomfort symptoms and potential visual impairment, which can result in damage to the ocular surface [ 1 , 2 ]. The Dry Eye Workshop II …

verfasst von:
Hiroki Maehara, Ryo Mukai, Yusuke Iitaka, Tetsuju Sekiryu

18.05.2024 | Clinical Investigation

Measurement of paracentral stereopsis using a new method with the binocular open perimeter imovifa® in normal adults

When the eyes fixate on an object, a slight misalignment occurs between the two retinal images (i.e., binocular disparity) because the two eyes are horizontally separated. By fusing the misalignment, binocular stereopsis is derived and depth …

verfasst von:
Akemi Wakayama, Chota Matsumoto, Keisuke Utamura, Ryo Narita, Shunji Kusaka

Open Access 13.05.2024 | Clinical Investigation

Long-term prognosis of acute primary angle closure in an east asian cohort

Acute primary angle closure (APAC) is an important sight-threatening emergency, especially in Asia. The incidence rates of APAC in Asians are reported to be higher than in Caucasians: 59.95 cases per 1,00,000 person-years among Koreans, 114 cases …

verfasst von:
Yoon Jeong, Ki Ho Park, Jin Wook Jeoung

23.11.2019 | Clinical Investigation

Association between axial length and in vivo human crystalline lens biometry during accommodation: a swept-source optical coherence tomography study

Accommodation is the adjustment of the dioptric power of the eye to obtain clear retinal images while looking at objects at various distances [ 1 ]. Although the basic model of accommodation dates back to the 1800s [ 1 , 2 ], the mechanisms behind …

verfasst von:
Takuhei Shoji, Naoko Kato, Sho Ishikawa, Hisashi Ibuki, Norihiro Yamada, Itaru Kimura, Kei Shinoda

23.11.2019 | Clinical Investigation

Autologous transplantation of conjunctiva by modifying simple limbal epithelial transplantation for limbal stem cell deficiency

A number of hereditary and acquired diseases are associated with limbal stem cell deficiency (LSCD), resulting in conjunctivalization, neovascularization, and stromal scarring of the cornea. LSCD is a major cause of ocular surface failure leading …

verfasst von:
Tohru Sakimoto, Akira Sakimoto, Satoru Yamagami

05.11.2019 | Clinical Investigation

Predictability of intraocular lens power calculation in eyes after phototherapeutic keratectomy

Phototherapeutic keratectomy (PTK) has been recognized as an effective surgical procedure to remove the diseased tissue by excimer laser photoablation in eyes with opaque corneas, such as those with granular corneal dystrophy (GCD) and band …

verfasst von:
Ryo Yoneyama, Kazutaka Kamiya, Kei Iijima, Masahide Takahashi, Nobuyuki Shoji