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2015 | OriginalPaper | Buchkapitel

32. Infektionen

verfasst von : Matthias Klein, PD Dr., Hans-Walter Pfister, Prof. Dr., Erich Schmutzhard, Prof. Dr., Uta Meyding-Lamadé, Prof. Dr., Corinna Schranz, Dr., Gabriele Arendt, Prof. Dr., Raimund Helbok, PD Dr., Bettina Pfausler, PD Dr., André Grabowski, Dr., Bodo Kress, Prof. Dr., Ronny Beer, PD Dr.

Erschienen in: NeuroIntensiv

Verlag: Springer Berlin Heidelberg

Zusammenfassung

In diesem Kapitel werden zunächst die für die Neurointensivmedizin wesentlichen bakteriellen Infektionen (Meningitis, spinale und Hirnabszesse, Spondylodiszitis, septisch-embolische Herdenzephalitis) abgehandelt, die trotz gezielt eingesetzter Antibiotika und neurochirurgischer Therapieoptionen noch mit einer erheblichen Morbidität und Mortalität behaftet sind. Besonderheiten wie neurovaskuläre Komplikationen, die Tuberkulose des Nervensystems, Neuroborreliose, Neurosyphilis und opportunistische Infektionen bei Immunsuppressionszuständen finden hierbei besondere Berücksichtigung. Der zweite Teil dieses Kapitels behandelt akute und chronische Virusinfektionen des ZNS sowie in einem gesonderten Abschnitt die HIVInfektion und HIV-assoziierte Krankheitsbilder sowie Parasitosen und Pilzinfektionen, die in Industrieländern seit Einführung der HAART bei HIV zwar eher seltener, aber mit zunehmender Globalisierung auch in unseren Breiten immer noch anzutreffen sind.
Literatur
1.
Zurück zum Zitat Ajdukiewicz KM, Cartwright KE, Scarborough M et al (2011) Glycerol adjuvant therapy in adults with bacterial meningitis in a high HIV seroprevalence setting in Malawi: a double-blind, randomised controlled trial. Lancet Infect Dis 11:293–300PubMedPubMedCentralCrossRef Ajdukiewicz KM, Cartwright KE, Scarborough M et al (2011) Glycerol adjuvant therapy in adults with bacterial meningitis in a high HIV seroprevalence setting in Malawi: a double-blind, randomised controlled trial. Lancet Infect Dis 11:293–300PubMedPubMedCentralCrossRef
2.
Zurück zum Zitat Auburtin M, Wolff M, Charpentier J et al (2006) Detrimental role of delayed antibiotic administration and penicillin-nonsusceptible strains in adult intensive care unit patients with pneumococcal meningitis: the PNEUMOREA prospective multicenter study. Crit Care Med 34:2758–2765PubMedCrossRef Auburtin M, Wolff M, Charpentier J et al (2006) Detrimental role of delayed antibiotic administration and penicillin-nonsusceptible strains in adult intensive care unit patients with pneumococcal meningitis: the PNEUMOREA prospective multicenter study. Crit Care Med 34:2758–2765PubMedCrossRef
3.
Zurück zum Zitat Brouwer MC, Heckenberg SG, de Gans J, Spanjaard L, Reitsma JB, van de Beek D (2010) Nationwide implementation of adjunctive dexamethasone therapy for pneumococcal meningitis. Neurology 75:1533–1539PubMedCrossRef Brouwer MC, Heckenberg SG, de Gans J, Spanjaard L, Reitsma JB, van de Beek D (2010) Nationwide implementation of adjunctive dexamethasone therapy for pneumococcal meningitis. Neurology 75:1533–1539PubMedCrossRef
4.
Zurück zum Zitat Brouwer MC, McIntyre P, de Gans J, Prasad K, van de BD (2010) Corticosteroids for acute bacterial meningitis. Cochrane Database Syst Rev 9:CD004405PubMed Brouwer MC, McIntyre P, de Gans J, Prasad K, van de BD (2010) Corticosteroids for acute bacterial meningitis. Cochrane Database Syst Rev 9:CD004405PubMed
5.
Zurück zum Zitat Casado FJ, Blanco QA (2001) ProcalcitoninA new marker for bacterial infection. An Esp Pediatr 54:69–73CrossRef Casado FJ, Blanco QA (2001) ProcalcitoninA new marker for bacterial infection. An Esp Pediatr 54:69–73CrossRef
6.
Zurück zum Zitat Chaudhuri A, Martin PM, Kennedy PG et al (2008) EFNS guideline on the management of community-acquired bacterial meningitis: report of an EFNS Task Force on acute bacterial meningitis in older children and adults. Eur J Neurol 15:649–659PubMedCrossRef Chaudhuri A, Martin PM, Kennedy PG et al (2008) EFNS guideline on the management of community-acquired bacterial meningitis: report of an EFNS Task Force on acute bacterial meningitis in older children and adults. Eur J Neurol 15:649–659PubMedCrossRef
7.
Zurück zum Zitat de Gans J, van de Beek D (2002) Dexamethasone in adults with bacterial meningitis. N Engl J Med 347:1549–1556PubMedCrossRef de Gans J, van de Beek D (2002) Dexamethasone in adults with bacterial meningitis. N Engl J Med 347:1549–1556PubMedCrossRef
8.
Zurück zum Zitat Dubos F, Korczowski B, Aygun DA et al (2008) Serum procalcitonin level and other biological markers to distinguish between bacterial and aseptic meningitis in children: a European multicenter case cohort study. Arch Pediatr Adolesc Med 162:1157–1163PubMedCrossRef Dubos F, Korczowski B, Aygun DA et al (2008) Serum procalcitonin level and other biological markers to distinguish between bacterial and aseptic meningitis in children: a European multicenter case cohort study. Arch Pediatr Adolesc Med 162:1157–1163PubMedCrossRef
9.
Zurück zum Zitat Durand ML, Calderwood SB, Weber DJ et al (1993) Acute bacterial meningitis in adults. A review of 493 episodes. N Engl J Med 328:21–28PubMedCrossRef Durand ML, Calderwood SB, Weber DJ et al (1993) Acute bacterial meningitis in adults. A review of 493 episodes. N Engl J Med 328:21–28PubMedCrossRef
10.
Zurück zum Zitat Hasbun R, Abrahams J, Jekel J, Quagliarello VJ (2001) Computed tomography of the head before lumbar puncture in adults with suspected meningitis. N Engl J Med 345:1727–1733PubMedCrossRef Hasbun R, Abrahams J, Jekel J, Quagliarello VJ (2001) Computed tomography of the head before lumbar puncture in adults with suspected meningitis. N Engl J Med 345:1727–1733PubMedCrossRef
11.
Zurück zum Zitat Heckenberg SG, de Gans J, Brouwer MC et al (2008) Clinical features, outcome, and meningococcal genotype in 258 adults with meningococcal meningitis: a prospective cohort study. Medicine (Baltimore) 87:185–192CrossRef Heckenberg SG, de Gans J, Brouwer MC et al (2008) Clinical features, outcome, and meningococcal genotype in 258 adults with meningococcal meningitis: a prospective cohort study. Medicine (Baltimore) 87:185–192CrossRef
12.
Zurück zum Zitat Heckenberg SG, Brouwer MC, van der Ende A, van de Beek D (2012) Adjunctive dexamethasone in adults with meningococcal meningitis. Neurology 79:1563–1569PubMedCrossRef Heckenberg SG, Brouwer MC, van der Ende A, van de Beek D (2012) Adjunctive dexamethasone in adults with meningococcal meningitis. Neurology 79:1563–1569PubMedCrossRef
13.
Zurück zum Zitat Imohl M, van der Linden M, Mutscher C, Reinert RR (2010) Serotype distribution of invasive pneumococcal disease during the first 60 days of life. Vaccine 28:4758–4762PubMedCrossRef Imohl M, van der Linden M, Mutscher C, Reinert RR (2010) Serotype distribution of invasive pneumococcal disease during the first 60 days of life. Vaccine 28:4758–4762PubMedCrossRef
14.
Zurück zum Zitat Kastenbauer S, Pfister HW (2003) Pneumococcal meningitis in adults: spectrum of complications and prognostic factors in a series of 87 cases. Brain 126(Pt 5):1015–1025PubMedCrossRef Kastenbauer S, Pfister HW (2003) Pneumococcal meningitis in adults: spectrum of complications and prognostic factors in a series of 87 cases. Brain 126(Pt 5):1015–1025PubMedCrossRef
15.
Zurück zum Zitat Klein M, Koedel U, Pfister HW (2006) Oxidative stress in pneumococcal meningitis: a future target for adjunctive therapy? Prog Neurobiol 80:269–280PubMedCrossRef Klein M, Koedel U, Pfister HW (2006) Oxidative stress in pneumococcal meningitis: a future target for adjunctive therapy? Prog Neurobiol 80:269–280PubMedCrossRef
16.
Zurück zum Zitat Klein M, Paul R, Angele B, Popp B, Pfister HW, Koedel U (2006) Protein expression pattern in experimental pneumococcal meningitis. Microbes Infect 8:974–983PubMedCrossRef Klein M, Paul R, Angele B, Popp B, Pfister HW, Koedel U (2006) Protein expression pattern in experimental pneumococcal meningitis. Microbes Infect 8:974–983PubMedCrossRef
17.
Zurück zum Zitat Klein M, Obermaier B, Angele B et al (2008) Innate immunity to pneumococcal infection of the central nervous system depends on toll-like receptor (TLR) 2 and TLR4. J Infect Dis 198:1028–1036PubMedCrossRef Klein M, Obermaier B, Angele B et al (2008) Innate immunity to pneumococcal infection of the central nervous system depends on toll-like receptor (TLR) 2 and TLR4. J Infect Dis 198:1028–1036PubMedCrossRef
18.
Zurück zum Zitat Klein M, Pfister HW, Leib SL, Koedel U (2009) Therapy of community-acquired acute bacterial meningitis: the clock is running. Expert Opin Pharmacother 10:2609–2623PubMedCrossRef Klein M, Pfister HW, Leib SL, Koedel U (2009) Therapy of community-acquired acute bacterial meningitis: the clock is running. Expert Opin Pharmacother 10:2609–2623PubMedCrossRef
19.
Zurück zum Zitat Klein M, Koedel U, Kastenbauer S et al (2010) Delayed cerebral thrombosis after initial good recovery from pneumococcal meningitis: past as prologue: delayed stroke as a parainfectious process of bacterial meningitis? Neurology 75:193–194PubMedCrossRef Klein M, Koedel U, Kastenbauer S et al (2010) Delayed cerebral thrombosis after initial good recovery from pneumococcal meningitis: past as prologue: delayed stroke as a parainfectious process of bacterial meningitis? Neurology 75:193–194PubMedCrossRef
20.
Zurück zum Zitat Klein M, Koedel U, Pfefferkorn T, Zeller G, Woehrl B, Pfister HW (2011) Arterial cerebrovascular complications in 94 adults with acute bacterial meningitis. Crit Care 15:R281PubMedPubMedCentralCrossRef Klein M, Koedel U, Pfefferkorn T, Zeller G, Woehrl B, Pfister HW (2011) Arterial cerebrovascular complications in 94 adults with acute bacterial meningitis. Crit Care 15:R281PubMedPubMedCentralCrossRef
21.
Zurück zum Zitat Koedel U, Klein M, Pfister HW (2010) New understandings on the pathophysiology of bacterial meningitis. Curr Opin Infect Dis 23:217–223PubMedCrossRef Koedel U, Klein M, Pfister HW (2010) New understandings on the pathophysiology of bacterial meningitis. Curr Opin Infect Dis 23:217–223PubMedCrossRef
22.
Zurück zum Zitat Kramer AH, Bleck TP (2008) Neurocritical care of patients with central nervous system infections. Curr Treat Options Neurol 10:201–211PubMedCrossRef Kramer AH, Bleck TP (2008) Neurocritical care of patients with central nervous system infections. Curr Treat Options Neurol 10:201–211PubMedCrossRef
23.
Zurück zum Zitat Krysan D (2009) Serum procalcitonin levels aid in distinguishing bacterial from aseptic meningitis in children. J Pediatr 154:773PubMedCrossRef Krysan D (2009) Serum procalcitonin levels aid in distinguishing bacterial from aseptic meningitis in children. J Pediatr 154:773PubMedCrossRef
24.
Zurück zum Zitat Molyneux EM, Walsh AL, Forsyth H et al (2002) Dexamethasone treatment in childhood bacterial meningitis in Malawi: a randomised controlled trial. Lancet 360:211–218PubMedCrossRef Molyneux EM, Walsh AL, Forsyth H et al (2002) Dexamethasone treatment in childhood bacterial meningitis in Malawi: a randomised controlled trial. Lancet 360:211–218PubMedCrossRef
25.
Zurück zum Zitat Molyneux EM, Kawaza K, Phiri A et al (2014) Glycerol and Acetaminophen as Adjuvant Therapy Did Not Affect the Outcome of Bacterial Meningitis in Malawian Children. Pediatr Infect Dis J 33:214–216PubMedCrossRef Molyneux EM, Kawaza K, Phiri A et al (2014) Glycerol and Acetaminophen as Adjuvant Therapy Did Not Affect the Outcome of Bacterial Meningitis in Malawian Children. Pediatr Infect Dis J 33:214–216PubMedCrossRef
26.
Zurück zum Zitat Mourvillier B, Tubach F, van de Beek D et al (2013) Induced hypothermia in severe bacterial meningitis: a randomized clinical trial. JAMA 310:2174–2183PubMedCrossRef Mourvillier B, Tubach F, van de Beek D et al (2013) Induced hypothermia in severe bacterial meningitis: a randomized clinical trial. JAMA 310:2174–2183PubMedCrossRef
27.
Zurück zum Zitat Nathan BR, Scheld WM (2002) The potential roles of C-reactive protein and procalcitonin concentrations in the serum and cerebrospinal fluid in the diagnosis of bacterial meningitis. Curr Clin Top Infect Dis 22:155–165PubMed Nathan BR, Scheld WM (2002) The potential roles of C-reactive protein and procalcitonin concentrations in the serum and cerebrospinal fluid in the diagnosis of bacterial meningitis. Curr Clin Top Infect Dis 22:155–165PubMed
28.
Zurück zum Zitat Nguyen TH, Tran TH, Thwaites G et al (2007) Dexamethasone in Vietnamese adolescents and adults with bacterial meningitis. N Engl J Med 357:2431–2440PubMedCrossRef Nguyen TH, Tran TH, Thwaites G et al (2007) Dexamethasone in Vietnamese adolescents and adults with bacterial meningitis. N Engl J Med 357:2431–2440PubMedCrossRef
29.
Zurück zum Zitat Ntziora F, Falagas ME (2007) Linezolid for the treatment of patients with central nervous system infection. Ann Pharmacother 41:296–308PubMedCrossRef Ntziora F, Falagas ME (2007) Linezolid for the treatment of patients with central nervous system infection. Ann Pharmacother 41:296–308PubMedCrossRef
30.
Zurück zum Zitat Pfister HW, Feiden W, Einhaupl KM (1993) Spectrum of complications during bacterial meningitis in adults. Results of a prospective clinical study. Arch Neurol 50:575–581PubMedCrossRef Pfister HW, Feiden W, Einhaupl KM (1993) Spectrum of complications during bacterial meningitis in adults. Results of a prospective clinical study. Arch Neurol 50:575–581PubMedCrossRef
31.
Zurück zum Zitat Pfister HW, Bühler R, Eiffert H, Nau R, Weber JR (2012) Ambulant erworbene bakterielle (eitrige) Meningitis. Leitlinien für Diagnostik und Therapie in der Neurologie der DGN. Thieme, Stuttgart, S 494–504 Pfister HW, Bühler R, Eiffert H, Nau R, Weber JR (2012) Ambulant erworbene bakterielle (eitrige) Meningitis. Leitlinien für Diagnostik und Therapie in der Neurologie der DGN. Thieme, Stuttgart, S 494–504
32.
Zurück zum Zitat Proulx N, Frechette D, Toye B, Chan J, Kravcik S (2005) Delays in the administration of antibiotics are associated with mortality from adult acute bacterial meningitis. QJM 98:291–298PubMedCrossRef Proulx N, Frechette D, Toye B, Chan J, Kravcik S (2005) Delays in the administration of antibiotics are associated with mortality from adult acute bacterial meningitis. QJM 98:291–298PubMedCrossRef
33.
Zurück zum Zitat RKI (Robert Koch Institut) (2009) Empfehlung und Begründung einer postexpositionellen Meningokokken-Impfung. Epidemiol Bull 31:314–317 RKI (Robert Koch Institut) (2009) Empfehlung und Begründung einer postexpositionellen Meningokokken-Impfung. Epidemiol Bull 31:314–317
34.
Zurück zum Zitat RKI (Robert Koch Institut) (2010) Meningokokkenerkrankungen. RKI Ratgeber Infektionskrankheiten – Merkblätter für Ärzte. www.rki.de RKI (Robert Koch Institut) (2010) Meningokokkenerkrankungen. RKI Ratgeber Infektionskrankheiten – Merkblätter für Ärzte. www.​rki.​de
35.
Zurück zum Zitat RKI (Robert Koch Institut) (2011) Aktuelle Statistik meldepflichtiger Infektionskrankheiten, Deutschland. Epidemiol Bull 3:21 RKI (Robert Koch Institut) (2011) Aktuelle Statistik meldepflichtiger Infektionskrankheiten, Deutschland. Epidemiol Bull 3:21
36.
Zurück zum Zitat RKI (Robert Koch Institut) (2013) Stellungnahme der Ständigen Impfkommission (STIKO) am Robert Koch-Institut (RKI) zum Stand der Bewertung des neuen Meningokokken-B-Impfstoffs Bexsero. Epidemiol Bull 49:495–498 RKI (Robert Koch Institut) (2013) Stellungnahme der Ständigen Impfkommission (STIKO) am Robert Koch-Institut (RKI) zum Stand der Bewertung des neuen Meningokokken-B-Impfstoffs Bexsero. Epidemiol Bull 49:495–498
37.
Zurück zum Zitat RKI (Robert Koch Institut) (2014) Jahresstatistik meldepflichtiger Infektionskrankheiten, Deutschland 2013. Robert Koch Institut. Epidemiol Bull 16:144 RKI (Robert Koch Institut) (2014) Jahresstatistik meldepflichtiger Infektionskrankheiten, Deutschland 2013. Robert Koch Institut. Epidemiol Bull 16:144
38.
Zurück zum Zitat Rupprecht TA, Pfister HW (2005) Clinical experience with linezolid for the treatment of central nervous system infections. Eur J Neurol 12:536–542PubMedCrossRef Rupprecht TA, Pfister HW (2005) Clinical experience with linezolid for the treatment of central nervous system infections. Eur J Neurol 12:536–542PubMedCrossRef
39.
Zurück zum Zitat Sakushima K, Hayashino Y, Kawaguchi T, Jackson JL, Fukuhara S (2011) Diagnostic accuracy of cerebrospinal fluid lactate for differentiating bacterial meningitis from aseptic meningitis: a meta-analysis. J Infect 62:255–262PubMedCrossRef Sakushima K, Hayashino Y, Kawaguchi T, Jackson JL, Fukuhara S (2011) Diagnostic accuracy of cerebrospinal fluid lactate for differentiating bacterial meningitis from aseptic meningitis: a meta-analysis. J Infect 62:255–262PubMedCrossRef
40.
Zurück zum Zitat Schut ES, Brouwer MC, de Gans J, Florquin S, Troost D, van de Beek D (2009) Delayed cerebral thrombosis after initial good recovery from pneumococcal meningitis. Neurology 73:1988–1995PubMedCrossRef Schut ES, Brouwer MC, de Gans J, Florquin S, Troost D, van de Beek D (2009) Delayed cerebral thrombosis after initial good recovery from pneumococcal meningitis. Neurology 73:1988–1995PubMedCrossRef
41.
Zurück zum Zitat Southwick FS (1995) Septic thrombophlebitis of major dural venous sinuses. Curr Clin Top Infect Dis 15:179–203PubMed Southwick FS (1995) Septic thrombophlebitis of major dural venous sinuses. Curr Clin Top Infect Dis 15:179–203PubMed
42.
Zurück zum Zitat Stephens DS, Greenwood B, Brandtzaeg P (2007) Epidemic meningitis, meningococcaemia, and Neisseria meningitidis. Lancet 369:2196–2210PubMedCrossRef Stephens DS, Greenwood B, Brandtzaeg P (2007) Epidemic meningitis, meningococcaemia, and Neisseria meningitidis. Lancet 369:2196–2210PubMedCrossRef
43.
Zurück zum Zitat van de Beek D, de Gans J, McIntyre P, Prasad K (2007) Corticosteroids for acute bacterial meningitis. Cochrane Database Syst Rev 1:CD004405PubMed van de Beek D, de Gans J, McIntyre P, Prasad K (2007) Corticosteroids for acute bacterial meningitis. Cochrane Database Syst Rev 1:CD004405PubMed
44.
Zurück zum Zitat van de Beek D, Farrar JJ, de Gans J et al (2010) Adjunctive dexamethasone in bacterial meningitis: a meta-analysis of individual patient data. Lancet Neurol 9:254–263PubMedPubMedCentralCrossRef van de Beek D, Farrar JJ, de Gans J et al (2010) Adjunctive dexamethasone in bacterial meningitis: a meta-analysis of individual patient data. Lancet Neurol 9:254–263PubMedPubMedCentralCrossRef
45.
Zurück zum Zitat van de Beek D, Brouwer MC, Thwaites GE, Tunkel AR (2012) Advances in treatment of bacterial meningitis. Lancet 380:1693–1702PubMedCrossRef van de Beek D, Brouwer MC, Thwaites GE, Tunkel AR (2012) Advances in treatment of bacterial meningitis. Lancet 380:1693–1702PubMedCrossRef
46.
Zurück zum Zitat Weisfelt M, van de Beek D, Spanjaard L, Reitsma JB, de Gans J (2006) Clinical features, complications, and outcome in adults with pneumococcal meningitis: a prospective case series. Lancet Neurol 5:123–129PubMedCrossRef Weisfelt M, van de Beek D, Spanjaard L, Reitsma JB, de Gans J (2006) Clinical features, complications, and outcome in adults with pneumococcal meningitis: a prospective case series. Lancet Neurol 5:123–129PubMedCrossRef
47.
Zurück zum Zitat Winkler F, Kastenbauer S, Yousry TA, Maerz U, Pfister HW (2002) Discrepancies between brain CT imaging and severely raised intracranial pressure proven by ventriculostomy in adults with pneumococcal meningitis. J Neurol 249:1292–1297PubMedCrossRef Winkler F, Kastenbauer S, Yousry TA, Maerz U, Pfister HW (2002) Discrepancies between brain CT imaging and severely raised intracranial pressure proven by ventriculostomy in adults with pneumococcal meningitis. J Neurol 249:1292–1297PubMedCrossRef
48.
Zurück zum Zitat Baddley JW, Salzman D, Pappas PG (2000) Fungal brain abscess in transplant recipients: epidemiologic microbiologic, and clinical features. Clin Transplant 16:419–424CrossRef Baddley JW, Salzman D, Pappas PG (2000) Fungal brain abscess in transplant recipients: epidemiologic microbiologic, and clinical features. Clin Transplant 16:419–424CrossRef
49.
Zurück zum Zitat Bernal E, Munoz A, Nunez ML, Cano A (2010) Multidrug-resistant spinal tuberculosis and giant paraspinal abscess. Med Clin (Barc) Nov 10 (Epub ahead of print) Bernal E, Munoz A, Nunez ML, Cano A (2010) Multidrug-resistant spinal tuberculosis and giant paraspinal abscess. Med Clin (Barc) Nov 10 (Epub ahead of print)
50.
Zurück zum Zitat Boviatsis EJ, Kouyialis AT, Stranjalis G et al (2003) CT-guided stereotactic biopsies of brain stem lesions: personal experience and literature review. Neurol Sci 24:97–102PubMedCrossRef Boviatsis EJ, Kouyialis AT, Stranjalis G et al (2003) CT-guided stereotactic biopsies of brain stem lesions: personal experience and literature review. Neurol Sci 24:97–102PubMedCrossRef
51.
Zurück zum Zitat Chang MC, Wu HT, Lee CH et al (2006) Tuberculous spondylitis and pyogenic spondylitis: comparative magnetic resonance imaging features. Spine 31:782–288PubMedCrossRef Chang MC, Wu HT, Lee CH et al (2006) Tuberculous spondylitis and pyogenic spondylitis: comparative magnetic resonance imaging features. Spine 31:782–288PubMedCrossRef
52.
Zurück zum Zitat Demir MK, Hakan T, Kilicoglu G et al (2007) Bacterial brain abscesses: prognostic value of an imaging severity index. Clin Radiol 62:564–572PubMedCrossRef Demir MK, Hakan T, Kilicoglu G et al (2007) Bacterial brain abscesses: prognostic value of an imaging severity index. Clin Radiol 62:564–572PubMedCrossRef
53.
Zurück zum Zitat Greenberg BM (2008) Central nervous system infections in the intensive care unit. Semin Neurol 28:682–689PubMedCrossRef Greenberg BM (2008) Central nervous system infections in the intensive care unit. Semin Neurol 28:682–689PubMedCrossRef
54.
Zurück zum Zitat Honda H, Warren DK (2009) Central nervous system infections: meningitis and brain abscess. Infect Dis Clin North Am 23:609–623PubMedCrossRef Honda H, Warren DK (2009) Central nervous system infections: meningitis and brain abscess. Infect Dis Clin North Am 23:609–623PubMedCrossRef
55.
Zurück zum Zitat Jansson AK, Enblad P, Sjolin J (2004) Efficacy and safety of cefotaxime in combination with metronidazole for empirical treatment of brain abscess in clinical practice: a retrospective study of 66 consecutive cases. Eur J Clin Microbiol Infect Dis 23:7–14PubMedCrossRef Jansson AK, Enblad P, Sjolin J (2004) Efficacy and safety of cefotaxime in combination with metronidazole for empirical treatment of brain abscess in clinical practice: a retrospective study of 66 consecutive cases. Eur J Clin Microbiol Infect Dis 23:7–14PubMedCrossRef
56.
Zurück zum Zitat Kang K, Lim I, Roh JK (2007) Positron emission tomographic findings in a tuberculous brain abscess. Ann Nucl Med 21:303–306PubMedCrossRef Kang K, Lim I, Roh JK (2007) Positron emission tomographic findings in a tuberculous brain abscess. Ann Nucl Med 21:303–306PubMedCrossRef
57.
Zurück zum Zitat Kao PT, Tseng HK, Liu CP et al (2003) Brain abscess: clinical analysis of 53 cases. J Microbiol Immunol Infect 36:129–136PubMed Kao PT, Tseng HK, Liu CP et al (2003) Brain abscess: clinical analysis of 53 cases. J Microbiol Immunol Infect 36:129–136PubMed
58.
Zurück zum Zitat Kupila L, Rantakokoo-Jalava K, Jalava J et al (2003) Aetiological diagnosis of brain abscesses and spinal infections: application of broad range bacterial polymerase chain reaction analysis. J Neurol Neurosurg Psychiatry 74:728–733PubMedPubMedCentralCrossRef Kupila L, Rantakokoo-Jalava K, Jalava J et al (2003) Aetiological diagnosis of brain abscesses and spinal infections: application of broad range bacterial polymerase chain reaction analysis. J Neurol Neurosurg Psychiatry 74:728–733PubMedPubMedCentralCrossRef
59.
Zurück zum Zitat Kutlay M, Colak A, Yildiz S et al (2005) Stereotactic aspiration and antibiotic treatment combined with hyperbaric oxygen therapy in the management of bacterial brain abscess. Neurosurg 57:1140–1146CrossRef Kutlay M, Colak A, Yildiz S et al (2005) Stereotactic aspiration and antibiotic treatment combined with hyperbaric oxygen therapy in the management of bacterial brain abscess. Neurosurg 57:1140–1146CrossRef
60.
Zurück zum Zitat Le Moal G, Landron C, Grollier G et al (2003) Characteristics of brain abscess with isolation of anaerobic bacteria. Scand J Infect Dis 35:318–321PubMedCrossRef Le Moal G, Landron C, Grollier G et al (2003) Characteristics of brain abscess with isolation of anaerobic bacteria. Scand J Infect Dis 35:318–321PubMedCrossRef
61.
Zurück zum Zitat Leuthardt EC, Wippold FJ, Oswood MC et al (2002) Diffusion-weighted MR imaging in the preoperative assessment of brain abscesses. Surg Neurol 58:395–402PubMedCrossRef Leuthardt EC, Wippold FJ, Oswood MC et al (2002) Diffusion-weighted MR imaging in the preoperative assessment of brain abscesses. Surg Neurol 58:395–402PubMedCrossRef
62.
Zurück zum Zitat Livraghi S, Melancia JP, Antunes jL (2003) The management of brain abscesses. Adv Tech Stand Neurosurg 28:285–313PubMed Livraghi S, Melancia JP, Antunes jL (2003) The management of brain abscesses. Adv Tech Stand Neurosurg 28:285–313PubMed
63.
Zurück zum Zitat Lu CH, Chang WN, Lui CC (2006) Strategies for the management of bacterial brain abscess. J Clin Neurosci 13:979–985PubMedCrossRef Lu CH, Chang WN, Lui CC (2006) Strategies for the management of bacterial brain abscess. J Clin Neurosci 13:979–985PubMedCrossRef
64.
Zurück zum Zitat Lumbiganon P, Chaikitpinyo A (2007) Antibiotics for brain abscesses in people with cyanotic congenital heart disease. Cochrane Database Syst Rev 18:CD004469 Lumbiganon P, Chaikitpinyo A (2007) Antibiotics for brain abscesses in people with cyanotic congenital heart disease. Cochrane Database Syst Rev 18:CD004469
65.
Zurück zum Zitat McClelland S, Hall WA (2007) Postoperative central nervous system infection: incidence and associated factors in 2111 nerosurgical procedures. Clin Infect Dis 45:55–59PubMedCrossRef McClelland S, Hall WA (2007) Postoperative central nervous system infection: incidence and associated factors in 2111 nerosurgical procedures. Clin Infect Dis 45:55–59PubMedCrossRef
66.
Zurück zum Zitat Mueller-Mang C, Castillo M, Mang TG et al (2007) Fungal versus bacterial brain abscesses: is diffusion-weighted MR imaging a useful tool in the differential diagnosis? Neuroradiol 49:651–657CrossRef Mueller-Mang C, Castillo M, Mang TG et al (2007) Fungal versus bacterial brain abscesses: is diffusion-weighted MR imaging a useful tool in the differential diagnosis? Neuroradiol 49:651–657CrossRef
67.
Zurück zum Zitat Pfister HW, Feiden W, Einhäupl KM (1993) The spectrum of complications during bacterial meningitis in adults: Results of a prospective clinical study. Arch Neurol 50:575–580PubMedCrossRef Pfister HW, Feiden W, Einhäupl KM (1993) The spectrum of complications during bacterial meningitis in adults: Results of a prospective clinical study. Arch Neurol 50:575–580PubMedCrossRef
68.
Zurück zum Zitat Saez-Llorens X (2003) Brain abscess in children. Semin Pediatr Infect Dis 2003 14:108–114CrossRef Saez-Llorens X (2003) Brain abscess in children. Semin Pediatr Infect Dis 2003 14:108–114CrossRef
69.
Zurück zum Zitat Skoutelis AT, Gogos CA, Maraziotis TE et al (2000) Managment of brain abscesses with sequential intravenous/oral antibiotic therapy. Eur J Clin Microbiol Infect Dis 19:332–335PubMedCrossRef Skoutelis AT, Gogos CA, Maraziotis TE et al (2000) Managment of brain abscesses with sequential intravenous/oral antibiotic therapy. Eur J Clin Microbiol Infect Dis 19:332–335PubMedCrossRef
70.
Zurück zum Zitat Su TM, Lan CM, Tsai YD et al (2003) Multilocated pyogenic brain abscess: experience in 25 patients. Neurosurgery 52:1075–1079PubMedCrossRef Su TM, Lan CM, Tsai YD et al (2003) Multilocated pyogenic brain abscess: experience in 25 patients. Neurosurgery 52:1075–1079PubMedCrossRef
71.
Zurück zum Zitat Tahir MZ, Hassan RU, Enam SA (2010) Management of an extensive spinal epidural abscess from C-1 to the sacrum. J Neurosurg Spine 13:780–783PubMedCrossRef Tahir MZ, Hassan RU, Enam SA (2010) Management of an extensive spinal epidural abscess from C-1 to the sacrum. J Neurosurg Spine 13:780–783PubMedCrossRef
72.
Zurück zum Zitat Tattevin P, Bruneel F, Clair B et al (2003) Bacterial brain abscesses: a retrospective study of 94 patients admitted to an intensive care Unit (1980–1999). Am J Med 115:143–146PubMedCrossRef Tattevin P, Bruneel F, Clair B et al (2003) Bacterial brain abscesses: a retrospective study of 94 patients admitted to an intensive care Unit (1980–1999). Am J Med 115:143–146PubMedCrossRef
73.
Zurück zum Zitat The “Infection in Neurosurgery” Working Party of the British Society for Antimicrobial Therapy (2000) The rational use of antibiotics in the treatment of brain abscess. Br J Neurosurg 14:525–530CrossRef The “Infection in Neurosurgery” Working Party of the British Society for Antimicrobial Therapy (2000) The rational use of antibiotics in the treatment of brain abscess. Br J Neurosurg 14:525–530CrossRef
74.
Zurück zum Zitat Tsai YD, Chang WN, Shen CC et al (2003) Intracranial suppuration: a clinical comparison of subdural empyemas and epidural abscesses. Surg Neurol 59:191–196PubMedCrossRef Tsai YD, Chang WN, Shen CC et al (2003) Intracranial suppuration: a clinical comparison of subdural empyemas and epidural abscesses. Surg Neurol 59:191–196PubMedCrossRef
75.
Zurück zum Zitat Tseng JH, Tseng MY (2006) Brain abscess in 142 patients: factors influencing outcome and mortality. Surg Neurol 65:557–562PubMedCrossRef Tseng JH, Tseng MY (2006) Brain abscess in 142 patients: factors influencing outcome and mortality. Surg Neurol 65:557–562PubMedCrossRef
76.
Zurück zum Zitat Tung GA, Rogg JM (2003) Diffusion-Weighted Imaging of Cerebritis. Am J Neuroradiol 24:1110–1113PubMed Tung GA, Rogg JM (2003) Diffusion-Weighted Imaging of Cerebritis. Am J Neuroradiol 24:1110–1113PubMed
77.
Zurück zum Zitat Visani P, Schmutzhard E, Trinka E et al (2006) Subcortical deficit pattern after brain abscess: a neuropsychological study. Eur J Neurol 13:599–603PubMedCrossRef Visani P, Schmutzhard E, Trinka E et al (2006) Subcortical deficit pattern after brain abscess: a neuropsychological study. Eur J Neurol 13:599–603PubMedCrossRef
78.
Zurück zum Zitat Wang VY, Chou D, Chin C (2010) Spine and spinal cord emergencies: vascular and infectious causes. Neuroimaging Clin N Am 20:639–650PubMedCrossRef Wang VY, Chou D, Chin C (2010) Spine and spinal cord emergencies: vascular and infectious causes. Neuroimaging Clin N Am 20:639–650PubMedCrossRef
79.
Zurück zum Zitat Yilmaz MH, Mete B, Kantarci F et al (2007) Tuberculous, brucellar and pyogenic spondylitis: comparison of magnetic resonance imaging findings and assessment of its value. South Med J 100:613–614PubMedCrossRef Yilmaz MH, Mete B, Kantarci F et al (2007) Tuberculous, brucellar and pyogenic spondylitis: comparison of magnetic resonance imaging findings and assessment of its value. South Med J 100:613–614PubMedCrossRef
80.
Zurück zum Zitat Younis RT, Lazar RH, Anand VK (2002) Intracranial complications of sinusitis: a 15-year review of 39 cases. Ear Nose Throat J 81:636–638 (640–642, 644)PubMed Younis RT, Lazar RH, Anand VK (2002) Intracranial complications of sinusitis: a 15-year review of 39 cases. Ear Nose Throat J 81:636–638 (640–642, 644)PubMed
81.
Zurück zum Zitat Aksamit AJ (2010) Whipple’s disease of the central nervous system. Handb Clin Neurol 96:231–237PubMedCrossRef Aksamit AJ (2010) Whipple’s disease of the central nervous system. Handb Clin Neurol 96:231–237PubMedCrossRef
83.
Zurück zum Zitat Andronikou S, Smith B, Hatherhill M et al (2004) Definitive neuroradiological diagnostic features of tuberculous meningitis in children. Pediatr Radiol 34:876–885PubMedCrossRef Andronikou S, Smith B, Hatherhill M et al (2004) Definitive neuroradiological diagnostic features of tuberculous meningitis in children. Pediatr Radiol 34:876–885PubMedCrossRef
84.
Zurück zum Zitat Asselman V, Thienemann F, Pepper DJ et al (2010) Central nervous system disorders after starting antiretroviral therapy in South Africa. AIDS 24:2871–2876PubMedCrossRef Asselman V, Thienemann F, Pepper DJ et al (2010) Central nervous system disorders after starting antiretroviral therapy in South Africa. AIDS 24:2871–2876PubMedCrossRef
85.
Zurück zum Zitat Banerjee B, Petersen K (2009) Psychosis following mycoplasma pneumonia. Mil Med 174:1001–1004PubMedCrossRef Banerjee B, Petersen K (2009) Psychosis following mycoplasma pneumonia. Mil Med 174:1001–1004PubMedCrossRef
86.
Zurück zum Zitat Bhigjee AI, Padayachee R, Paruk H et al (2007) Diagnosis of tuberculous meningitis: clinical and laboratory parameters. Int J Infect Dis 11:348–354PubMedCrossRef Bhigjee AI, Padayachee R, Paruk H et al (2007) Diagnosis of tuberculous meningitis: clinical and laboratory parameters. Int J Infect Dis 11:348–354PubMedCrossRef
87.
Zurück zum Zitat Black DF, Aksamit AJ, Morris JM (2010) MR imaging of central nervous system Whipple disease: a 15-year review. AJNR Am J Neuroradiol 31:1493–1497PubMedCrossRef Black DF, Aksamit AJ, Morris JM (2010) MR imaging of central nervous system Whipple disease: a 15-year review. AJNR Am J Neuroradiol 31:1493–1497PubMedCrossRef
88.
Zurück zum Zitat Boillat N, Greub G (2007) Rickettsiosis: a clinical approach. Rev Med Suisse 16:1222–1227 Boillat N, Greub G (2007) Rickettsiosis: a clinical approach. Rev Med Suisse 16:1222–1227
89.
90.
Zurück zum Zitat Bross JE, Gordon G (1991) Nocardial Meningitis: Case Reports and Review. Rev Infect Dis 13:160–165PubMedCrossRef Bross JE, Gordon G (1991) Nocardial Meningitis: Case Reports and Review. Rev Infect Dis 13:160–165PubMedCrossRef
91.
Zurück zum Zitat Christmann D, Hansmann Y, Remy V et al (2002) Tick-borne neurological diseases. Rev Neurol 158:993–997PubMed Christmann D, Hansmann Y, Remy V et al (2002) Tick-borne neurological diseases. Rev Neurol 158:993–997PubMed
92.
Zurück zum Zitat Chotmongkol V, Teerajetgul Y, Yodwut C (2006) Cerebrospinal fluid adenosine deaminase activity for the diagnosis of tuberculous meningitis in adults. SE Asian J Trop Med Public Health 37:948–952 Chotmongkol V, Teerajetgul Y, Yodwut C (2006) Cerebrospinal fluid adenosine deaminase activity for the diagnosis of tuberculous meningitis in adults. SE Asian J Trop Med Public Health 37:948–952
93.
Zurück zum Zitat Cunha BA, Pherez FM (2009) C. pneumoniae community-acquired pneumonia (CAP) in mimicking Mycoplasma pneumonia meningoencephalitis complicated by asthma. Heart Lung 38:530–533PubMedCrossRef Cunha BA, Pherez FM (2009) C. pneumoniae community-acquired pneumonia (CAP) in mimicking Mycoplasma pneumonia meningoencephalitis complicated by asthma. Heart Lung 38:530–533PubMedCrossRef
94.
Zurück zum Zitat Dumler J, Madigan JE, Pusterlia N et al (2007) Ehrlichioses in Humans: Epidemiology, clinical Presentations, Diagnosis and Treatment. Clin Infect 45:45–51CrossRef Dumler J, Madigan JE, Pusterlia N et al (2007) Ehrlichioses in Humans: Epidemiology, clinical Presentations, Diagnosis and Treatment. Clin Infect 45:45–51CrossRef
95.
Zurück zum Zitat Fenollar F, Puechal X, Raoult D (2007) Whipple’s disease. N Engl Med 356:55–56CrossRef Fenollar F, Puechal X, Raoult D (2007) Whipple’s disease. N Engl Med 356:55–56CrossRef
96.
Zurück zum Zitat Garcia Monco JC (2006) Tuberculosis and other mycobacterial Infections. In: Noseworthy JH (Hrsg) Neurological Therapeutics – Principles and Practice, 2. Aufl. Informa Health Care Abingdon, Oxon, S 1011–1020 Garcia Monco JC (2006) Tuberculosis and other mycobacterial Infections. In: Noseworthy JH (Hrsg) Neurological Therapeutics – Principles and Practice, 2. Aufl. Informa Health Care Abingdon, Oxon, S 1011–1020
97.
Zurück zum Zitat Godia CE, Esteve CM, Campello RA et al (2007) Cerebral saltwasting syndrome due to infectious diseases of the central nervous system. Med Clin 128:278–279CrossRef Godia CE, Esteve CM, Campello RA et al (2007) Cerebral saltwasting syndrome due to infectious diseases of the central nervous system. Med Clin 128:278–279CrossRef
98.
Zurück zum Zitat Gouriet F, Lepidi H, Habib G et al (2007) From Cat Scratch disease to endocarditis, the possible natural history of Bartonella henselae infection. BMC Inf Dis 7:30–35CrossRef Gouriet F, Lepidi H, Habib G et al (2007) From Cat Scratch disease to endocarditis, the possible natural history of Bartonella henselae infection. BMC Inf Dis 7:30–35CrossRef
99.
Zurück zum Zitat Hainard A, Tiberti N, Robin X et al (2010) Matrix metalloproteinase-9 and intercellular adhesion molecule 1 are powerful staging markers for human African trypanosomiasis. Trop Med Int Health 16:119–126PubMedCrossRef Hainard A, Tiberti N, Robin X et al (2010) Matrix metalloproteinase-9 and intercellular adhesion molecule 1 are powerful staging markers for human African trypanosomiasis. Trop Med Int Health 16:119–126PubMedCrossRef
100.
Zurück zum Zitat Hongo I, Bloch KC (2006) Ehrlichia infection of the central nervous system. Curr Treat Options Neurol 8:179–184PubMedCrossRef Hongo I, Bloch KC (2006) Ehrlichia infection of the central nervous system. Curr Treat Options Neurol 8:179–184PubMedCrossRef
101.
Zurück zum Zitat Jha DK, Mishra V, Choudhary A et al (2007) Factors affecting the outcome of neuroendoscopy in patients with tuberculous meningitis hydrocephalus: a preliminary study. Surg Neurol 68:35–41PubMedCrossRef Jha DK, Mishra V, Choudhary A et al (2007) Factors affecting the outcome of neuroendoscopy in patients with tuberculous meningitis hydrocephalus: a preliminary study. Surg Neurol 68:35–41PubMedCrossRef
102.
Zurück zum Zitat Inan AS, Ceran N, Erdem I et al (2010) Neurobrucellosis with transient ischemic attack, vasculopathic changes, intracerebral granulomas and basal ganglia infarction: a case report. J Med Case Reports 4:340–342PubMedCentralCrossRef Inan AS, Ceran N, Erdem I et al (2010) Neurobrucellosis with transient ischemic attack, vasculopathic changes, intracerebral granulomas and basal ganglia infarction: a case report. J Med Case Reports 4:340–342PubMedCentralCrossRef
103.
Zurück zum Zitat Kalita J, Misra UK, Ranjan P (2007) Predictors of long-term neurological sequelae of tuberculous meningitis: a multivariate analysis. Eur J Neurol 14:33–37PubMedCrossRef Kalita J, Misra UK, Ranjan P (2007) Predictors of long-term neurological sequelae of tuberculous meningitis: a multivariate analysis. Eur J Neurol 14:33–37PubMedCrossRef
104.
Zurück zum Zitat Kazar J (2005) Coxiella burnetii infection. Ann NY Academy Sci 1063:105–114CrossRef Kazar J (2005) Coxiella burnetii infection. Ann NY Academy Sci 1063:105–114CrossRef
105.
Zurück zum Zitat Koskiniemi M (1993) CNS manifestations associated with Mycoplasma pneumoniae infections: summary of cases at the University of Helsinki and review. Clin Infect Dis 17:52–57CrossRef Koskiniemi M (1993) CNS manifestations associated with Mycoplasma pneumoniae infections: summary of cases at the University of Helsinki and review. Clin Infect Dis 17:52–57CrossRef
106.
107.
Zurück zum Zitat Lee CH, Lui CC, Liu JW (2007) Immune reconstitution syndrome in a patient with AIDS with paradoxically deteriorating brain tuberculoma. AIDS Patient Care 21:234–239CrossRef Lee CH, Lui CC, Liu JW (2007) Immune reconstitution syndrome in a patient with AIDS with paradoxically deteriorating brain tuberculoma. AIDS Patient Care 21:234–239CrossRef
108.
Zurück zum Zitat Lin JJ, Harn JH, Hsu YD et al (1995) Rapid diagnosis of tuberculous meningitis by polymerase chain reaction assay of cerebrospinal fluid. J Neurol 242:147–152PubMedCrossRef Lin JJ, Harn JH, Hsu YD et al (1995) Rapid diagnosis of tuberculous meningitis by polymerase chain reaction assay of cerebrospinal fluid. J Neurol 242:147–152PubMedCrossRef
109.
Zurück zum Zitat Mahajan SK, Rolain JM, Kanga A, Raoult D (2010) Scrub typhus involving central nervous system, India, 2004–2006. Emerg Infect Dis 16:1641–1643PubMedPubMedCentralCrossRef Mahajan SK, Rolain JM, Kanga A, Raoult D (2010) Scrub typhus involving central nervous system, India, 2004–2006. Emerg Infect Dis 16:1641–1643PubMedPubMedCentralCrossRef
110.
Zurück zum Zitat Masoodi I, Farooq O, Ahmad I et al (2010) Acute disseminated encephalomyelitis as the first presentation of CNS tuberculosis: report of a case with brief review. Ger Med Sci 8:1–4 Masoodi I, Farooq O, Ahmad I et al (2010) Acute disseminated encephalomyelitis as the first presentation of CNS tuberculosis: report of a case with brief review. Ger Med Sci 8:1–4
111.
Zurück zum Zitat Noyola DE, Holder DL, Fishman MA et al (1999) Recurrent encephalopathy in cat-scratch disease. Pediatr Infect Dis 18:567–568CrossRef Noyola DE, Holder DL, Fishman MA et al (1999) Recurrent encephalopathy in cat-scratch disease. Pediatr Infect Dis 18:567–568CrossRef
112.
Zurück zum Zitat Pappas G, Papadimitriou P, Akriditis N et al (2006) The new global map of human brucellosis. Lancet Infect Dis 6:91–99PubMedCrossRef Pappas G, Papadimitriou P, Akriditis N et al (2006) The new global map of human brucellosis. Lancet Infect Dis 6:91–99PubMedCrossRef
113.
Zurück zum Zitat Pfister HW (2002) Meningits. Kohlhammer, Stuttgart Pfister HW (2002) Meningits. Kohlhammer, Stuttgart
114.
Zurück zum Zitat Prasad K, Singh MB (2008) Corticosteroids for managing tuberculous meningitis. Cochrane Database Syst Rev 2008:CD002244 Prasad K, Singh MB (2008) Corticosteroids for managing tuberculous meningitis. Cochrane Database Syst Rev 2008:CD002244
115.
Zurück zum Zitat Przybojewski AS, Wilmshurst J (2006) Objective CT criteria to determine the presence of abnormal basal enhancement in children with suspected tuberculous meningitis. Pediatr Radiol 36:687–696PubMedCrossRef Przybojewski AS, Wilmshurst J (2006) Objective CT criteria to determine the presence of abnormal basal enhancement in children with suspected tuberculous meningitis. Pediatr Radiol 36:687–696PubMedCrossRef
116.
Zurück zum Zitat Rafi W, Venkataswamy MM, Ravi V et al (2007) Rapid diagnosis of tuberculous meningitis: a comparative evaluation of in-house PCR assays involving three mycobacterial DNA sequences, IS6110-MPB-64 and 65 kDa antigen. J Neurol Sci 252:163–168PubMedCrossRef Rafi W, Venkataswamy MM, Ravi V et al (2007) Rapid diagnosis of tuberculous meningitis: a comparative evaluation of in-house PCR assays involving three mycobacterial DNA sequences, IS6110-MPB-64 and 65 kDa antigen. J Neurol Sci 252:163–168PubMedCrossRef
117.
Zurück zum Zitat Raoult D, Birg MI, La Scola B et al (2000) Cultivation of the bacillus of Whipple’s disease. N Engl J Med 342:620–625PubMedCrossRef Raoult D, Birg MI, La Scola B et al (2000) Cultivation of the bacillus of Whipple’s disease. N Engl J Med 342:620–625PubMedCrossRef
118.
119.
Zurück zum Zitat Roca B, Bahamonde D (2006) Tuberulous Meningitis Presenting with Unusually Severe Hyponatremia. The Mount Sinai J Med 73:1029–1030 Roca B, Bahamonde D (2006) Tuberulous Meningitis Presenting with Unusually Severe Hyponatremia. The Mount Sinai J Med 73:1029–1030
120.
Zurück zum Zitat Schiffer JT, Sterling TR (2007) Timing of antiretroviral therapy initiation in tuberculosis patients with AIDS: a decision analysis. J Acquir Immune Defic Syndr 44:229–234PubMedCrossRef Schiffer JT, Sterling TR (2007) Timing of antiretroviral therapy initiation in tuberculosis patients with AIDS: a decision analysis. J Acquir Immune Defic Syndr 44:229–234PubMedCrossRef
121.
Zurück zum Zitat Schmutzhard E et al (2008) Atypische erregerbedingte Meningoencephalitis. In: Diener HC (Hrsg) Leitlinien für Diagnostik und Therapie in der Neurologie, 4. Aufl. Thieme, Stuttgart Schmutzhard E et al (2008) Atypische erregerbedingte Meningoencephalitis. In: Diener HC (Hrsg) Leitlinien für Diagnostik und Therapie in der Neurologie, 4. Aufl. Thieme, Stuttgart
122.
Zurück zum Zitat Schmutzhard E, Pfister HW (2001) Seltene bakterielle Infektionen des Nervensystems. Akt Neurol 28:373–382CrossRef Schmutzhard E, Pfister HW (2001) Seltene bakterielle Infektionen des Nervensystems. Akt Neurol 28:373–382CrossRef
123.
Zurück zum Zitat Schoeman J, Mansvelt E, Springer P et al (2007) Coagulant and fibrinolytic status in tuberculous meningitis. Pediatr Infect Di J 26:428–431CrossRef Schoeman J, Mansvelt E, Springer P et al (2007) Coagulant and fibrinolytic status in tuberculous meningitis. Pediatr Infect Di J 26:428–431CrossRef
124.
Zurück zum Zitat Skiba V, Barner KC (2009) Central nervous system manifestations of Q fever responsive to steroids. Mil Med 174:857–859PubMedCrossRef Skiba V, Barner KC (2009) Central nervous system manifestations of Q fever responsive to steroids. Mil Med 174:857–859PubMedCrossRef
125.
Zurück zum Zitat Socan M (1994) Chlamydia pneumoniae and meningoencephalitis. N Engl J Med 11:331–406 Socan M (1994) Chlamydia pneumoniae and meningoencephalitis. N Engl J Med 11:331–406
126.
Zurück zum Zitat Srikanth SG, Taly AB, Nagarajan K et al (2007) Clinicoradiological features of tuberculous meningitis in patients over 50 years of age. J Neurol Neurosurg Psychiatr 78:536–538PubMedCrossRef Srikanth SG, Taly AB, Nagarajan K et al (2007) Clinicoradiological features of tuberculous meningitis in patients over 50 years of age. J Neurol Neurosurg Psychiatr 78:536–538PubMedCrossRef
127.
Zurück zum Zitat Tezer H, Kara A, Haliloglu G et al (2008) Mycoplasma pneumonia-associated transverse myelitis with unexpected rapid response to macrolide therapy: a case report. Turk J Pediatr 50:585–588PubMed Tezer H, Kara A, Haliloglu G et al (2008) Mycoplasma pneumonia-associated transverse myelitis with unexpected rapid response to macrolide therapy: a case report. Turk J Pediatr 50:585–588PubMed
128.
Zurück zum Zitat Thurtell MJ, Keed AB, Yan M et al (2007) Tuberculous cranial pachymeningitis. Neurology 68:298–300PubMedCrossRef Thurtell MJ, Keed AB, Yan M et al (2007) Tuberculous cranial pachymeningitis. Neurology 68:298–300PubMedCrossRef
129.
Zurück zum Zitat Wang VY, Chou D, Chin C (2010) Spine and spinal cord emergencies: vascular and infectious causes. Neuroimaging Clin N Am 20:639–650PubMedCrossRef Wang VY, Chou D, Chin C (2010) Spine and spinal cord emergencies: vascular and infectious causes. Neuroimaging Clin N Am 20:639–650PubMedCrossRef
130.
Zurück zum Zitat Yis U, Kurul SH, Cakmakci H, Dirik E (2008) Mycoplasma pneumonia: nervous system complications in childhood and review of the literature. Eur J Pediatr 167:973–978PubMedCrossRef Yis U, Kurul SH, Cakmakci H, Dirik E (2008) Mycoplasma pneumonia: nervous system complications in childhood and review of the literature. Eur J Pediatr 167:973–978PubMedCrossRef
132.
Zurück zum Zitat Blank LJ, Rompalo AM, Erbelding EJ, Zenilman JM, Ghanem KG (2011) Treatment of syphilis in HIV-infected subjects: a systematic review of the literature. Sex Transm Infect 87:9–16PubMedCrossRef Blank LJ, Rompalo AM, Erbelding EJ, Zenilman JM, Ghanem KG (2011) Treatment of syphilis in HIV-infected subjects: a systematic review of the literature. Sex Transm Infect 87:9–16PubMedCrossRef
133.
Zurück zum Zitat Ghanem KG (2010) Review: Neurosyphilis: A historical perspective and review. CNS Neurosci Ther 16:157–168CrossRef Ghanem KG (2010) Review: Neurosyphilis: A historical perspective and review. CNS Neurosci Ther 16:157–168CrossRef
134.
Zurück zum Zitat Hajjaj KN (2010) Status epilepticus revealing syphilitic meningoencephalitis. Acta Neurol Belg 110:263–267PubMed Hajjaj KN (2010) Status epilepticus revealing syphilitic meningoencephalitis. Acta Neurol Belg 110:263–267PubMed
135.
Zurück zum Zitat Halperin JJ (2007) Diagnosis and treatment of the neuromuscular manifestations of Lyme disease. Curr Treat Options Neuro 9:93–100CrossRef Halperin JJ (2007) Diagnosis and treatment of the neuromuscular manifestations of Lyme disease. Curr Treat Options Neuro 9:93–100CrossRef
136.
137.
Zurück zum Zitat Halperin JJ, Shapiro ED, Logigian E et al (2007) Practice parameter: treatment of nervous system Lyme disease (an evidence based review): report of the Quality of Standards Subcommittee of the American Academy of Neurology. Neurology 69:91–102PubMedCrossRef Halperin JJ, Shapiro ED, Logigian E et al (2007) Practice parameter: treatment of nervous system Lyme disease (an evidence based review): report of the Quality of Standards Subcommittee of the American Academy of Neurology. Neurology 69:91–102PubMedCrossRef
138.
Zurück zum Zitat Jenke AC, Stoek LM, Zilbauer M, Wirth S, Borusiak P (2011) Facial palsy: Etiology, outcome and management in children. Eur J Paediatr Neurol 15:209–213PubMedCrossRef Jenke AC, Stoek LM, Zilbauer M, Wirth S, Borusiak P (2011) Facial palsy: Etiology, outcome and management in children. Eur J Paediatr Neurol 15:209–213PubMedCrossRef
139.
Zurück zum Zitat Kobayashi J, Nakagawa Y, Tobisawa S, Isozaki E, Koide R (2011) Deterioration of MRI findings related to Jarisch-Herxheimer reaction in a patient with neurosyphilis. J Neurol 258:699–701PubMedCrossRef Kobayashi J, Nakagawa Y, Tobisawa S, Isozaki E, Koide R (2011) Deterioration of MRI findings related to Jarisch-Herxheimer reaction in a patient with neurosyphilis. J Neurol 258:699–701PubMedCrossRef
140.
Zurück zum Zitat Makhani N, Morris SK, Page AV et al (2011) A Twist On Lyme: The challenge of Diagnosing European Lyme Neuroborreliosis. J Clin Microbiol 49:455–457PubMedCrossRef Makhani N, Morris SK, Page AV et al (2011) A Twist On Lyme: The challenge of Diagnosing European Lyme Neuroborreliosis. J Clin Microbiol 49:455–457PubMedCrossRef
141.
Zurück zum Zitat Richter D, Postic D, Sertour N et al (2006) Delineation of Borrelia burgdorferi sensu lato species by multilocus sequence analysis and confirmation of the delineation of Borrelia spielmanii sp. nov. Int J Syst Evol Microbiol 56:873–881PubMedCrossRef Richter D, Postic D, Sertour N et al (2006) Delineation of Borrelia burgdorferi sensu lato species by multilocus sequence analysis and confirmation of the delineation of Borrelia spielmanii sp. nov. Int J Syst Evol Microbiol 56:873–881PubMedCrossRef
142.
Zurück zum Zitat Robertson J, Guy E, Andrews N et al (2000) European multicenter study of immunoblotting in serodiagnosis of lyme borreliosis. J Clin Microbiol 38:2097–2102PubMedPubMedCentral Robertson J, Guy E, Andrews N et al (2000) European multicenter study of immunoblotting in serodiagnosis of lyme borreliosis. J Clin Microbiol 38:2097–2102PubMedPubMedCentral
143.
Zurück zum Zitat Roos K (2006) Neurosyphilis. In: Noseworthy JH (Hrsg) Neurological Therapeutics-Principles and Practice, 2. Aufl. Informa Health Care, Abingdon, Oxon, S 1021–1024 Roos K (2006) Neurosyphilis. In: Noseworthy JH (Hrsg) Neurological Therapeutics-Principles and Practice, 2. Aufl. Informa Health Care, Abingdon, Oxon, S 1021–1024
144.
Zurück zum Zitat Schmutzhard E, Pfausler B, Gasse T et al (1995) Verlauf und Langzeitfolgen der chronischen Neuroborreliose. Wien Med Wochenschr 145:183–186PubMed Schmutzhard E, Pfausler B, Gasse T et al (1995) Verlauf und Langzeitfolgen der chronischen Neuroborreliose. Wien Med Wochenschr 145:183–186PubMed
145.
Zurück zum Zitat van Burgel ND, Oosterloo M, Kroon FP, van Dam AP (2010) Severe course of Lyme neuroborreliosis in an HIV-1 positive patient; case report and review of the literature. BMC Neurol 10:117–121PubMedPubMedCentralCrossRef van Burgel ND, Oosterloo M, Kroon FP, van Dam AP (2010) Severe course of Lyme neuroborreliosis in an HIV-1 positive patient; case report and review of the literature. BMC Neurol 10:117–121PubMedPubMedCentralCrossRef
146.
147.
Zurück zum Zitat Wilske B, Fingerle V, Schulte-Spechtel U (2007) Microbiological and serological diagnosis of Lyme Borreliosis. FEMS Immunol Med Microbiol 49:13–21PubMedCrossRef Wilske B, Fingerle V, Schulte-Spechtel U (2007) Microbiological and serological diagnosis of Lyme Borreliosis. FEMS Immunol Med Microbiol 49:13–21PubMedCrossRef
148.
Zurück zum Zitat Workowski KA, Berman SM (2010) Sexually transmitted diseases treatment. Guidelines 59(RR12):1–110 Workowski KA, Berman SM (2010) Sexually transmitted diseases treatment. Guidelines 59(RR12):1–110
149.
Zurück zum Zitat Wormser GP, Nadelman RB, Dattwyler RJ et al (2000) Practice guidelines for the treatment of Lyme disease. The Infectious Diseases Society of America. Clin Infect Dis 31:1–14PubMedCrossRef Wormser GP, Nadelman RB, Dattwyler RJ et al (2000) Practice guidelines for the treatment of Lyme disease. The Infectious Diseases Society of America. Clin Infect Dis 31:1–14PubMedCrossRef
150.
Zurück zum Zitat Abzug MJ, Cloud G, Bradley J, Sanchez PJ, Romero J, Powel D, Lepow M, Mani C, Capparelli EV, Blount S, Lakeman F, Whitley RJ, Kimberlin DW (2003) Double blind placebo-controlled trial of pleconaril in infants with enterovirus meningitis. Pediatr Infect Dis J 22:335–341PubMed Abzug MJ, Cloud G, Bradley J, Sanchez PJ, Romero J, Powel D, Lepow M, Mani C, Capparelli EV, Blount S, Lakeman F, Whitley RJ, Kimberlin DW (2003) Double blind placebo-controlled trial of pleconaril in infants with enterovirus meningitis. Pediatr Infect Dis J 22:335–341PubMed
151.
Zurück zum Zitat Adamo MA, Deshaies EM (2008) Emergency decompressive craniectomy for fulminating infectious encephalitis. J Neurosurg 108:174–176PubMedCrossRef Adamo MA, Deshaies EM (2008) Emergency decompressive craniectomy for fulminating infectious encephalitis. J Neurosurg 108:174–176PubMedCrossRef
152.
Zurück zum Zitat Armangue T, Leypoldt F, Dalmau J (2014) Autoimmune encephalitis as differential diagnosis of infectious encephalitis. Curr Opin Neurol 27:361–368PubMedPubMedCentralCrossRef Armangue T, Leypoldt F, Dalmau J (2014) Autoimmune encephalitis as differential diagnosis of infectious encephalitis. Curr Opin Neurol 27:361–368PubMedPubMedCentralCrossRef
153.
154.
Zurück zum Zitat Baringer JR, Pisani P (1994) Herpes simplex virus genomes in human nervous system tissue analyzed by polymerase chain reaction. Ann Neurol 36:823–829PubMedCrossRef Baringer JR, Pisani P (1994) Herpes simplex virus genomes in human nervous system tissue analyzed by polymerase chain reaction. Ann Neurol 36:823–829PubMedCrossRef
155.
Zurück zum Zitat Bossart KN, Zhu Z, Middleton D et al (2009) A neutralizing human monoclonal antibody protects against lethal disease in a new ferret model of acute nipah virus infection. Plos Pathog 5:e1000642PubMedPubMedCentralCrossRef Bossart KN, Zhu Z, Middleton D et al (2009) A neutralizing human monoclonal antibody protects against lethal disease in a new ferret model of acute nipah virus infection. Plos Pathog 5:e1000642PubMedPubMedCentralCrossRef
156.
Zurück zum Zitat Casrouge A, Zhang SY, Eidenschenk C et al (2006) Herpes simplex virus encephalitis in human UNC-93B deficiency. Science 314:308–312PubMedCrossRef Casrouge A, Zhang SY, Eidenschenk C et al (2006) Herpes simplex virus encephalitis in human UNC-93B deficiency. Science 314:308–312PubMedCrossRef
157.
Zurück zum Zitat Center for Disease Control, Prevention (2004) Recovery of a Patient from Clinical Rabies. MMW 53:1171–1173 Center for Disease Control, Prevention (2004) Recovery of a Patient from Clinical Rabies. MMW 53:1171–1173
158.
Zurück zum Zitat C D C (1999) Update: Outbreak of Nipah virus – Malaysia and Singapore. MMWR 48:335–337 C D C (1999) Update: Outbreak of Nipah virus – Malaysia and Singapore. MMWR 48:335–337
159.
161.
Zurück zum Zitat Cinque P, Bossolasco S, Lundkvist A (2003) Molecular analysis of cerebrospinal fluid in viral diseases of the central nervous system. J Clin Virol 26:1–28PubMedCrossRef Cinque P, Bossolasco S, Lundkvist A (2003) Molecular analysis of cerebrospinal fluid in viral diseases of the central nervous system. J Clin Virol 26:1–28PubMedCrossRef
162.
Zurück zum Zitat Collaborative Antiviral Study Group, http://clinicaltrials.gov/show/NCT00031486: A Phase III Double-Blind, Placebo-Controlled Trial of Long Term Therapy of Herpes Simplex Encephalitis (HSE): An Evaluation of Valacyclovir (CASG-204), lead sponsor National Institute of Allergy and Infectious Diseases (NIAID) Collaborative Antiviral Study Group, http://​clinicaltrials.​gov/​show/​NCT00031486: A Phase III Double-Blind, Placebo-Controlled Trial of Long Term Therapy of Herpes Simplex Encephalitis (HSE): An Evaluation of Valacyclovir (CASG-204), lead sponsor National Institute of Allergy and Infectious Diseases (NIAID)
163.
Zurück zum Zitat Corssmit EP, Leverstein-van Hall MA, Portegies P, Bakker P (1997) Severe neurological complications in association with Epstein-Barr virus infection. J Neurovirol 3:460–464PubMedCrossRef Corssmit EP, Leverstein-van Hall MA, Portegies P, Bakker P (1997) Severe neurological complications in association with Epstein-Barr virus infection. J Neurovirol 3:460–464PubMedCrossRef
164.
Zurück zum Zitat Defang GN, Khetawat D, Broder CC, Quinnan GV Jr. (2010) Induction of neutralizing antibodies to Hendra and Nipah glycoproteins using a Venezuelan equine encephalitis virus in vivo expression system. Vaccine 29:212–220PubMedPubMedCentralCrossRef Defang GN, Khetawat D, Broder CC, Quinnan GV Jr. (2010) Induction of neutralizing antibodies to Hendra and Nipah glycoproteins using a Venezuelan equine encephalitis virus in vivo expression system. Vaccine 29:212–220PubMedPubMedCentralCrossRef
165.
Zurück zum Zitat DGN – Deutsche Gesellschaft für Neurologie (2012) Leitlinie „Virale Meningoenzephalitiden“ DGN – Deutsche Gesellschaft für Neurologie (2012) Leitlinie „Virale Meningoenzephalitiden“
166.
Zurück zum Zitat Falcone S, Post MJ (2000) Encephalitis, cerebritis, and brain abscess: pathophysiology and imaging findings. Neuroimaging Clin N Am 10:333–353PubMed Falcone S, Post MJ (2000) Encephalitis, cerebritis, and brain abscess: pathophysiology and imaging findings. Neuroimaging Clin N Am 10:333–353PubMed
167.
Zurück zum Zitat Fusco D, Krawitz P, LaRussa P, Steinberg S, Gershon A (2010) Jacobs J VZV meningitis following varicella vaccine. J Clin Virol 48:275–277PubMedCrossRef Fusco D, Krawitz P, LaRussa P, Steinberg S, Gershon A (2010) Jacobs J VZV meningitis following varicella vaccine. J Clin Virol 48:275–277PubMedCrossRef
168.
Zurück zum Zitat Granerod J, Cunningham R, Zuckerman M et al (2010) Causality in acute encephalitis: defining aetiologies. Epidemiol Infect 138:783–800PubMedCrossRef Granerod J, Cunningham R, Zuckerman M et al (2010) Causality in acute encephalitis: defining aetiologies. Epidemiol Infect 138:783–800PubMedCrossRef
169.
Zurück zum Zitat Granerod J, Tam CC, Crowcroft NS, Davies NWS, Borchert M, Thomas SL (2010) Challenge of the unknown: A systematic review of acute encephalitis in non-outbreak situations. Neurology 75:924–932PubMedCrossRef Granerod J, Tam CC, Crowcroft NS, Davies NWS, Borchert M, Thomas SL (2010) Challenge of the unknown: A systematic review of acute encephalitis in non-outbreak situations. Neurology 75:924–932PubMedCrossRef
170.
Zurück zum Zitat Gurley ES, Montgomery JM, Hossain MJ et al (2007) Person-to-person transmission of Nipah virus in Bangladeshi community. Emerg Infect Dis 13(7):1031–1037PubMedPubMedCentralCrossRef Gurley ES, Montgomery JM, Hossain MJ et al (2007) Person-to-person transmission of Nipah virus in Bangladeshi community. Emerg Infect Dis 13(7):1031–1037PubMedPubMedCentralCrossRef
171.
Zurück zum Zitat Hacohen Y, Deiva K, Pettingill P, Waters P, Siddiqui A, Chretien P, Menson E, Lin JP, Tardieu M, Vincent A, Lim MJ (2014) N-methyl-D-aspartate receptor antibodies in post-herpes simplex virus encephalitis neurological relapse. Mov Disord 29:90–96PubMedCrossRef Hacohen Y, Deiva K, Pettingill P, Waters P, Siddiqui A, Chretien P, Menson E, Lin JP, Tardieu M, Vincent A, Lim MJ (2014) N-methyl-D-aspartate receptor antibodies in post-herpes simplex virus encephalitis neurological relapse. Mov Disord 29:90–96PubMedCrossRef
172.
Zurück zum Zitat Haglund M, Forsgren M, Lindh G, Lindquist L (1996) A 10-year follow-up study of tick-borne encephalitis in the Stockholm area and a review of the literature: need for a vaccination strategy. Scand J Infect Dis 28:217–224PubMedCrossRef Haglund M, Forsgren M, Lindh G, Lindquist L (1996) A 10-year follow-up study of tick-borne encephalitis in the Stockholm area and a review of the literature: need for a vaccination strategy. Scand J Infect Dis 28:217–224PubMedCrossRef
173.
Zurück zum Zitat Hauser SL (2006) Harrison’s Neurology in Clinical Medicine. McGraw-Hill, New York Hauser SL (2006) Harrison’s Neurology in Clinical Medicine. McGraw-Hill, New York
174.
Zurück zum Zitat Henquell C, Chambon M, Bailly JL, Alcaraz S, De Champs C, Archimbaud C, Labbe A, Charbonne F, Peigue-Lafeuille H (2001) Prospective analysis of 61 cases of enteroviral meningitis: interest of systematic genome detection in cerebrospinal fluid irrespective of cytologic examination results. J Clin Virol 21:29–35PubMedCrossRef Henquell C, Chambon M, Bailly JL, Alcaraz S, De Champs C, Archimbaud C, Labbe A, Charbonne F, Peigue-Lafeuille H (2001) Prospective analysis of 61 cases of enteroviral meningitis: interest of systematic genome detection in cerebrospinal fluid irrespective of cytologic examination results. J Clin Virol 21:29–35PubMedCrossRef
175.
Zurück zum Zitat Kaiser R (2002) Tick-borne encephalitis (TBE) in Germany and clinical course of the disease. Int J Med Microbiol 291(33):58–61PubMedCrossRef Kaiser R (2002) Tick-borne encephalitis (TBE) in Germany and clinical course of the disease. Int J Med Microbiol 291(33):58–61PubMedCrossRef
176.
Zurück zum Zitat Kaiser R (2011) Langzeitprognose bei primär myelitischer Manifestation der FSME. Eine Verlaufsanalyse über 10 Jahre. Nervenarzt 82:1020–1025PubMedCrossRef Kaiser R (2011) Langzeitprognose bei primär myelitischer Manifestation der FSME. Eine Verlaufsanalyse über 10 Jahre. Nervenarzt 82:1020–1025PubMedCrossRef
177.
Zurück zum Zitat Kamei S (2006) Trends in the management of herpes simplex encephalitis. Rinsho Shinkeigaku 46:950–953PubMed Kamei S (2006) Trends in the management of herpes simplex encephalitis. Rinsho Shinkeigaku 46:950–953PubMed
179.
Zurück zum Zitat Kutleša M, Baršić B (2012) Therapeutic hypothermia for severe adult Herpes simplex virus encephalitis. Wien Klin Wochenschr 124:855–858PubMedCrossRef Kutleša M, Baršić B (2012) Therapeutic hypothermia for severe adult Herpes simplex virus encephalitis. Wien Klin Wochenschr 124:855–858PubMedCrossRef
180.
Zurück zum Zitat Lee KE, Umapathi T, Tan CB et al (1999) The neurological manifestations of Nipah virus encephalitis, a novel paramyxovirus. Ann Neurol 464:28–32 Lee KE, Umapathi T, Tan CB et al (1999) The neurological manifestations of Nipah virus encephalitis, a novel paramyxovirus. Ann Neurol 464:28–32
182.
Zurück zum Zitat Leypoldt F, Titulaer MJ, Aguilar E, Walther J, Bönstrup M, Havemeister S, Teegen B, Lütgehetmann M, Rosenkranz M, Magnus T, Dalmau J (2013) Herpes simplex virus-1 encephalitis can trigger anti-NMDA receptor encephalitis: case report. Neurology 81:1637–1639PubMedPubMedCentralCrossRef Leypoldt F, Titulaer MJ, Aguilar E, Walther J, Bönstrup M, Havemeister S, Teegen B, Lütgehetmann M, Rosenkranz M, Magnus T, Dalmau J (2013) Herpes simplex virus-1 encephalitis can trigger anti-NMDA receptor encephalitis: case report. Neurology 81:1637–1639PubMedPubMedCentralCrossRef
183.
Zurück zum Zitat Livorsi D, Anderson E, Qureshi S, Howard M, Wang YF, Paredes F-C (2010) Brainstem encephalitis: an unusual presentation of herpes simplex virus infection. J Neurol 257:1432–1437PubMedCrossRef Livorsi D, Anderson E, Qureshi S, Howard M, Wang YF, Paredes F-C (2010) Brainstem encephalitis: an unusual presentation of herpes simplex virus infection. J Neurol 257:1432–1437PubMedCrossRef
184.
Zurück zum Zitat Martinez-Torres F, Menon S, Pritsch M, Victor N, Jenetzky E, Jensen K, Schielke E, Schmutzhard E, de Gans J, Chung CH, Luntz S, Hacke W, Meyding-Lamadé U (2008) Protocol for German trial of Acyclovir and corticosteroids in Herpes-simplex-virus-encephalitis (GACHE): a multicenter, multinational, randomized, double-blind, placebo-controlled German, Austrian and Dutch trial. BMC Neurol 8:40PubMedPubMedCentralCrossRef Martinez-Torres F, Menon S, Pritsch M, Victor N, Jenetzky E, Jensen K, Schielke E, Schmutzhard E, de Gans J, Chung CH, Luntz S, Hacke W, Meyding-Lamadé U (2008) Protocol for German trial of Acyclovir and corticosteroids in Herpes-simplex-virus-encephalitis (GACHE): a multicenter, multinational, randomized, double-blind, placebo-controlled German, Austrian and Dutch trial. BMC Neurol 8:40PubMedPubMedCentralCrossRef
185.
Zurück zum Zitat Meyding-Lamade UK, Lamade WR, Wildemann BT, Sarto K, Hacke W (1999) Herpes simplex virus encephalitis: chronic progressive cerebral magnetic resonance imaging abnormalities in patients despite good clinical recovery. Clin Infect Dis 28:148–149PubMedCrossRef Meyding-Lamade UK, Lamade WR, Wildemann BT, Sarto K, Hacke W (1999) Herpes simplex virus encephalitis: chronic progressive cerebral magnetic resonance imaging abnormalities in patients despite good clinical recovery. Clin Infect Dis 28:148–149PubMedCrossRef
186.
Zurück zum Zitat Meyding-Lamadé U, Strank C (2012) Herpesvirus infections of the central nervous system in immunocompromised patients. Ther Adv Neurol Disord 5:279–296PubMedPubMedCentralCrossRef Meyding-Lamadé U, Strank C (2012) Herpesvirus infections of the central nervous system in immunocompromised patients. Ther Adv Neurol Disord 5:279–296PubMedPubMedCentralCrossRef
187.
Zurück zum Zitat Ooi MH, Wong SC, Lewthwaite P, Cardosa MJ, Solomon T (2010) Clinical features, diagnosis, and management of enterovirus 71. Lancet Neurol 9:1097–1105PubMedCrossRef Ooi MH, Wong SC, Lewthwaite P, Cardosa MJ, Solomon T (2010) Clinical features, diagnosis, and management of enterovirus 71. Lancet Neurol 9:1097–1105PubMedCrossRef
188.
Zurück zum Zitat Porotto M, Rockx B, Yokoyama CC, Talekar A, Devito I, Palermo LM, Liu J, Cortese R, Lu M, Feldmann H, Pessi A (2010) Moscona A Inhibition of Nipah virus infection in vivo: targeting an early stage of paramyxovirus fusion activation during viral entr. PLoS Pathog 6:e1001168PubMedPubMedCentralCrossRef Porotto M, Rockx B, Yokoyama CC, Talekar A, Devito I, Palermo LM, Liu J, Cortese R, Lu M, Feldmann H, Pessi A (2010) Moscona A Inhibition of Nipah virus infection in vivo: targeting an early stage of paramyxovirus fusion activation during viral entr. PLoS Pathog 6:e1001168PubMedPubMedCentralCrossRef
189.
Zurück zum Zitat Reiber H, Felgenhauer K (1987) Protein transfer at the blood cerebrospinal fluid barrier and the quantitation of the humoral immune response within the central nervous system. Clin Chim Acta 163:319–328PubMedCrossRef Reiber H, Felgenhauer K (1987) Protein transfer at the blood cerebrospinal fluid barrier and the quantitation of the humoral immune response within the central nervous system. Clin Chim Acta 163:319–328PubMedCrossRef
191.
Zurück zum Zitat Robert-Koch-Institut RKI– (2014) FSME: Risikogebiete in Deutschland. Epidemiol Bull 15:121–136 Robert-Koch-Institut RKI– (2014) FSME: Risikogebiete in Deutschland. Epidemiol Bull 15:121–136
192.
Zurück zum Zitat Romero JR, Newland JG (2003) Viral meningitis and encephalitis: traditional and emerging viral agents. Semin Pediatr Infect Dis 14:72–82PubMedCrossRef Romero JR, Newland JG (2003) Viral meningitis and encephalitis: traditional and emerging viral agents. Semin Pediatr Infect Dis 14:72–82PubMedCrossRef
193.
Zurück zum Zitat Schmutzhard E (2001) Viral infections of the CNS with special emphasis on herpes simplex infections. J Neurol 248:469–477PubMedCrossRef Schmutzhard E (2001) Viral infections of the CNS with special emphasis on herpes simplex infections. J Neurol 248:469–477PubMedCrossRef
194.
Zurück zum Zitat Schwab S, Junger E, Spranger M, Dorfler A, Albert F, Steiner HH, Hacke W (1997) Craniectomy: an aggressive treatment approach in severe encephalitis. Neurology 48:412–417PubMedCrossRef Schwab S, Junger E, Spranger M, Dorfler A, Albert F, Steiner HH, Hacke W (1997) Craniectomy: an aggressive treatment approach in severe encephalitis. Neurology 48:412–417PubMedCrossRef
195.
Zurück zum Zitat Sener RN (2002) Diffusion MRI in Rasmussen’s encephalitis, herpes simplex encephalitis, and bacterial meningoencephalitis. Comput Med Imaging Graph 26:327–332PubMedCrossRef Sener RN (2002) Diffusion MRI in Rasmussen’s encephalitis, herpes simplex encephalitis, and bacterial meningoencephalitis. Comput Med Imaging Graph 26:327–332PubMedCrossRef
196.
197.
Zurück zum Zitat Sköldenberg B, Forsgren M, Alestig K, Bergström T, Burman L, Dahlqvist E, Forkman A, Frydén A, Lövgren K, Norlin K et al (1984) Acyclovir versus vidarabine in herpes simplex encephalitis. Randomised multicentre study in consecutive Swedish patients. Lancet 29:707–711CrossRef Sköldenberg B, Forsgren M, Alestig K, Bergström T, Burman L, Dahlqvist E, Forkman A, Frydén A, Lövgren K, Norlin K et al (1984) Acyclovir versus vidarabine in herpes simplex encephalitis. Randomised multicentre study in consecutive Swedish patients. Lancet 29:707–711CrossRef
198.
Zurück zum Zitat Solomon T, Michael BD, Smith PE, Sanderson F, Davies NWS, Hart IJ, Holland M, Easton A, Buckley C, Kneen R, Beeching (2012) Management of suspected viral encephalitis in adults – Association of British Neurologists and British Infection Association National Guidelines. J Infection 64:347–373CrossRef Solomon T, Michael BD, Smith PE, Sanderson F, Davies NWS, Hart IJ, Holland M, Easton A, Buckley C, Kneen R, Beeching (2012) Management of suspected viral encephalitis in adults – Association of British Neurologists and British Infection Association National Guidelines. J Infection 64:347–373CrossRef
199.
Zurück zum Zitat Sommer JB, Heckmann JG, Kraus J, Neundörfer B, Erbguth FJ (2000) Generalized brain edema in non-purulent meningoencephalitis. The anti-edema effect of therapy with dexamethasone. Nervenarzt 71:112–115PubMedCrossRef Sommer JB, Heckmann JG, Kraus J, Neundörfer B, Erbguth FJ (2000) Generalized brain edema in non-purulent meningoencephalitis. The anti-edema effect of therapy with dexamethasone. Nervenarzt 71:112–115PubMedCrossRef
200.
Zurück zum Zitat Steiner I, Budka H, Chaudhuri A, Koskiniemi M, Sainio K, Salonen O, Kennedy PG (2010) Viral meningoencephalitis: a review of diagnostic methods and guidelines for management. Eur J Neurol 17(999) Steiner I, Budka H, Chaudhuri A, Koskiniemi M, Sainio K, Salonen O, Kennedy PG (2010) Viral meningoencephalitis: a review of diagnostic methods and guidelines for management. Eur J Neurol 17(999)
201.
Zurück zum Zitat Tan CT, Goh KJ, Wong KT et al (2002) Relapsed and late-onset Nipah encephalitis. Ann Neurol 51:703–708PubMedCrossRef Tan CT, Goh KJ, Wong KT et al (2002) Relapsed and late-onset Nipah encephalitis. Ann Neurol 51:703–708PubMedCrossRef
202.
Zurück zum Zitat Taskin E, Turgut M, Kilic M et al (2004) Serum procalcitonin and cerebrospinal fluid cytokines level in children with meningitis. Mediators of Inflammation 13:269–273PubMedPubMedCentralCrossRef Taskin E, Turgut M, Kilic M et al (2004) Serum procalcitonin and cerebrospinal fluid cytokines level in children with meningitis. Mediators of Inflammation 13:269–273PubMedPubMedCentralCrossRef
203.
Zurück zum Zitat Thakur KT, Motta M, Asemota AO, Kirsch HL, Benavides D, Schneider EB, McArthur JC, Geocadin RG, Venkatesan A (2013) Predictors of outcome in acute encephalitis. Neurology 81:793–800PubMedPubMedCentralCrossRef Thakur KT, Motta M, Asemota AO, Kirsch HL, Benavides D, Schneider EB, McArthur JC, Geocadin RG, Venkatesan A (2013) Predictors of outcome in acute encephalitis. Neurology 81:793–800PubMedPubMedCentralCrossRef
204.
Zurück zum Zitat Thomson RB Jr., Bertram H (2001) Laboratory diagnosis of central nervous system infections. Infect Dis Clin North Am 15:1047–1071PubMedCrossRef Thomson RB Jr., Bertram H (2001) Laboratory diagnosis of central nervous system infections. Infect Dis Clin North Am 15:1047–1071PubMedCrossRef
205.
Zurück zum Zitat Tyler KL (2004) Update on herpes simplex encephalitis. Rev Neurol Dis 1:169–178PubMed Tyler KL (2004) Update on herpes simplex encephalitis. Rev Neurol Dis 1:169–178PubMed
206.
207.
Zurück zum Zitat Utley TF, Ogden JA, Gibb A, McGrath N, Anderson NE (1997) The long-term neuropsychological outcome of herpes simplex encephalitis in a series of unselected survivors. Neuropsychiatry Neuropsychol Behav Neurol 10:180–189PubMed Utley TF, Ogden JA, Gibb A, McGrath N, Anderson NE (1997) The long-term neuropsychological outcome of herpes simplex encephalitis in a series of unselected survivors. Neuropsychiatry Neuropsychol Behav Neurol 10:180–189PubMed
208.
Zurück zum Zitat Wagner I, Staykov D, Volbers B, Kloska S, Dörfler A, Schwab S, Bardutzky J (2011) Mild hypothermia for space-occupying Herpes simplex virus encephalitis. Minerva Anestesiol 77:371–374PubMed Wagner I, Staykov D, Volbers B, Kloska S, Dörfler A, Schwab S, Bardutzky J (2011) Mild hypothermia for space-occupying Herpes simplex virus encephalitis. Minerva Anestesiol 77:371–374PubMed
209.
Zurück zum Zitat Whitley RJ, Lakeman AD, Nahmias A, Roizman B (1982) Dna restriction-enzyme analysis of herpes simplex virus isolates obtained from patients with encephalitis. N Engl J Med 307:1060–1062PubMedCrossRef Whitley RJ, Lakeman AD, Nahmias A, Roizman B (1982) Dna restriction-enzyme analysis of herpes simplex virus isolates obtained from patients with encephalitis. N Engl J Med 307:1060–1062PubMedCrossRef
210.
Zurück zum Zitat Whitley RJ, Alford CA, Hirsch MS, Schooley RT, Luby JP, Aoki FY, Hanley D, Nahmias AJ, Soong SJ (1986) Vidarabine versus acyclovir therapy in herpes simplex encephalitis. N Engl J Med 314:144–149PubMedCrossRef Whitley RJ, Alford CA, Hirsch MS, Schooley RT, Luby JP, Aoki FY, Hanley D, Nahmias AJ, Soong SJ (1986) Vidarabine versus acyclovir therapy in herpes simplex encephalitis. N Engl J Med 314:144–149PubMedCrossRef
211.
Zurück zum Zitat Whitley RJ, Gnann JW (2002) Viral encephalitis: familiar infections and emerging pathogens. Lancet 359:507–513PubMedCrossRef Whitley RJ, Gnann JW (2002) Viral encephalitis: familiar infections and emerging pathogens. Lancet 359:507–513PubMedCrossRef
213.
Zurück zum Zitat Wildemann B, Ehrhart K, Storch-Hagenlocher B, Meyding-Lamade U, Steinvorth S, Hacke W, Haas J (1997) Quantitation of herpes simplex virus type 1 DNA in cells of cerebrospinal fluid of patients with herpes simplex virus encephalitis. Neurology 48:1341–1346PubMedCrossRef Wildemann B, Ehrhart K, Storch-Hagenlocher B, Meyding-Lamade U, Steinvorth S, Hacke W, Haas J (1997) Quantitation of herpes simplex virus type 1 DNA in cells of cerebrospinal fluid of patients with herpes simplex virus encephalitis. Neurology 48:1341–1346PubMedCrossRef
214.
Zurück zum Zitat Wong M, Connolly AM, Noetzel MJ (1999) Poliomyelitis-like syndrome associated with Epstein-Barr virus infection. Pediatr Neurol 20:235–237PubMedCrossRef Wong M, Connolly AM, Noetzel MJ (1999) Poliomyelitis-like syndrome associated with Epstein-Barr virus infection. Pediatr Neurol 20:235–237PubMedCrossRef
215.
Zurück zum Zitat Wong KT, Shieh WJ, Kumar S et al (2002) Nipah Virus Pathology Working Group. Nipah virus Infection: pathology and pathogenesis of an emerging paramyxoviral zoonosis. Am J Pathol 161:2153–2167PubMedPubMedCentralCrossRef Wong KT, Shieh WJ, Kumar S et al (2002) Nipah Virus Pathology Working Group. Nipah virus Infection: pathology and pathogenesis of an emerging paramyxoviral zoonosis. Am J Pathol 161:2153–2167PubMedPubMedCentralCrossRef
216.
Zurück zum Zitat Berger JR, Aksamit AJ, Clifford DB et al (2013) PML diagnostic criteria: consensus statement from the AAN neuroinfectious disease section. Neurology 80:1430–1438PubMedPubMedCentralCrossRef Berger JR, Aksamit AJ, Clifford DB et al (2013) PML diagnostic criteria: consensus statement from the AAN neuroinfectious disease section. Neurology 80:1430–1438PubMedPubMedCentralCrossRef
218.
Zurück zum Zitat Brew BJ, Davies NW, Cinque P, Clifford DB, Nath A (2010) Progressive multifocal leukencephalopathy and other forms of JC virus disease. Nat Rev Neurol 6:667–679PubMedCrossRef Brew BJ, Davies NW, Cinque P, Clifford DB, Nath A (2010) Progressive multifocal leukencephalopathy and other forms of JC virus disease. Nat Rev Neurol 6:667–679PubMedCrossRef
219.
Zurück zum Zitat Campbell H, Andrews N, Brown KE, Miller E (2007) Review of the effect of measles vaccination on the epidemiology of SSPE. Int J Epidemiol 36:1334–1348PubMedCrossRef Campbell H, Andrews N, Brown KE, Miller E (2007) Review of the effect of measles vaccination on the epidemiology of SSPE. Int J Epidemiol 36:1334–1348PubMedCrossRef
220.
Zurück zum Zitat Clifford DB, Yiannoutsos C, Glicksman M, Simpson DM, Singer EJ, Piliero PJ, Marra CM, Francis GS, McArthur JC, Tyler KL, Tselis AC, Hyslop NE (1999) HAART improves prognosis in HIV-associated progressive multifocal leukoencephalopathy. Neurology 52:623–625PubMedCrossRef Clifford DB, Yiannoutsos C, Glicksman M, Simpson DM, Singer EJ, Piliero PJ, Marra CM, Francis GS, McArthur JC, Tyler KL, Tselis AC, Hyslop NE (1999) HAART improves prognosis in HIV-associated progressive multifocal leukoencephalopathy. Neurology 52:623–625PubMedCrossRef
221.
Zurück zum Zitat Clifford DB, Nath A, Cinque P, Brew BJ, Zivadinov R, Gorelik L, Zhao Z, Duda P (2013) A study of mefloquine treatment for progressive multifocal leukoencephalopathy: results and exploration of predic- tors of PML outcomes. J Neurovirol 19:351–358PubMedPubMedCentralCrossRef Clifford DB, Nath A, Cinque P, Brew BJ, Zivadinov R, Gorelik L, Zhao Z, Duda P (2013) A study of mefloquine treatment for progressive multifocal leukoencephalopathy: results and exploration of predic- tors of PML outcomes. J Neurovirol 19:351–358PubMedPubMedCentralCrossRef
222.
Zurück zum Zitat Dahlhaus S, Hoepner R, Chan A, Kleiter I, Adams O, Lukas C, Hellwig K, Gold R (2013) Disease course and outcome of 15 monocentrically treated natalizumab-associated progressive multifocal leukencephalopathy patients. J Neurol Neurosurg Psychiatry 84:1068–1074PubMedPubMedCentralCrossRef Dahlhaus S, Hoepner R, Chan A, Kleiter I, Adams O, Lukas C, Hellwig K, Gold R (2013) Disease course and outcome of 15 monocentrically treated natalizumab-associated progressive multifocal leukencephalopathy patients. J Neurol Neurosurg Psychiatry 84:1068–1074PubMedPubMedCentralCrossRef
223.
Zurück zum Zitat Gasnault J, Costagliola D, Hendel-Chavez H, Dulioust A, Pakianather S, Mazet AA, de Goer de Herve MG, Lancar R, Lascaux AS, Porte L, Delfraissy JF, Taoufik Y, ANRS 125 Trial Team (2011) Improved survival of HIV-1-infected patients with progressive multifocal leukoencephalopathy receiving early 5-drug combination antiretroviral therapy. PLoS One 6(6):e20967–125PubMedPubMedCentralCrossRef Gasnault J, Costagliola D, Hendel-Chavez H, Dulioust A, Pakianather S, Mazet AA, de Goer de Herve MG, Lancar R, Lascaux AS, Porte L, Delfraissy JF, Taoufik Y, ANRS 125 Trial Team (2011) Improved survival of HIV-1-infected patients with progressive multifocal leukoencephalopathy receiving early 5-drug combination antiretroviral therapy. PLoS One 6(6):e20967–125PubMedPubMedCentralCrossRef
224.
Zurück zum Zitat Gorelik L, Lerner M, Bixler S et al (2010) Anti-JCV Antibodies: Implications for PML Risk Stratification. Ann Neurol 68:295–303PubMedCrossRef Gorelik L, Lerner M, Bixler S et al (2010) Anti-JCV Antibodies: Implications for PML Risk Stratification. Ann Neurol 68:295–303PubMedCrossRef
225.
Zurück zum Zitat Hauser S et al (2006) Harrison’s Neurology in Clinical Medicine. McGraw-Hill, New York Hauser S et al (2006) Harrison’s Neurology in Clinical Medicine. McGraw-Hill, New York
226.
Zurück zum Zitat Helbok R, Broessner G, Pfauler B, Schmutzhard E (2009) Chronic meningitis. J Neurol 256:168–175PubMedCrossRef Helbok R, Broessner G, Pfauler B, Schmutzhard E (2009) Chronic meningitis. J Neurol 256:168–175PubMedCrossRef
227.
Zurück zum Zitat Khanna N, Elzi L, Mueller NJ, Garzoni C, Cavassini M, Fux CA, Vernazza P, Bernasconi E, Battegay M, Hirsch HH, Swiss HIV Cohort Study (2009) Incidence and outcome of progressive multifocal leukoencephalopathy over 20 years of the Swiss HIV Cohort Study. Clin Infect Dis (48):1459–1466 Khanna N, Elzi L, Mueller NJ, Garzoni C, Cavassini M, Fux CA, Vernazza P, Bernasconi E, Battegay M, Hirsch HH, Swiss HIV Cohort Study (2009) Incidence and outcome of progressive multifocal leukoencephalopathy over 20 years of the Swiss HIV Cohort Study. Clin Infect Dis (48):1459–1466
228.
Zurück zum Zitat Manning L, Laman M, Edoni H, Mueller I, Karunajeewa HA, Smith D, Hwaiwhanje I, Siba PM, Davis TM (2011) Subacute sclerosing panencephalitis in papua new guinean children: the cost of continuing inadequate measles vaccine coverage. PLoS Negl Trop Dis 5:e932PubMedPubMedCentralCrossRef Manning L, Laman M, Edoni H, Mueller I, Karunajeewa HA, Smith D, Hwaiwhanje I, Siba PM, Davis TM (2011) Subacute sclerosing panencephalitis in papua new guinean children: the cost of continuing inadequate measles vaccine coverage. PLoS Negl Trop Dis 5:e932PubMedPubMedCentralCrossRef
229.
Zurück zum Zitat Mentzer D, Prestel J, Adams O et al (2012) Case definition for progressive multifocal leukoencephalopathy following treatment with monoclonal antibodies. J Neurol Neurosurg Psychiatry 83:927–933PubMedCrossRef Mentzer D, Prestel J, Adams O et al (2012) Case definition for progressive multifocal leukoencephalopathy following treatment with monoclonal antibodies. J Neurol Neurosurg Psychiatry 83:927–933PubMedCrossRef
230.
Zurück zum Zitat Molloy ES, Calabrese LH (2008) Progressive multifocal leukoencephalopathy in patients with rheumatic diseases: are patients with systemic lupus erythematosus at particular risk? Autoimmun Rev 8:144–146PubMedCrossRef Molloy ES, Calabrese LH (2008) Progressive multifocal leukoencephalopathy in patients with rheumatic diseases: are patients with systemic lupus erythematosus at particular risk? Autoimmun Rev 8:144–146PubMedCrossRef
231.
Zurück zum Zitat Nagoshi K, Sadakane A, Nakamura Y, Yamada M, Mizusawa H (2011) Duration of Prion Disease is Longer in Japan Than in Other Countries. J Epidemiol May 28, Epub ahead of print Nagoshi K, Sadakane A, Nakamura Y, Yamada M, Mizusawa H (2011) Duration of Prion Disease is Longer in Japan Than in Other Countries. J Epidemiol May 28, Epub ahead of print
232.
Zurück zum Zitat Owens GP, Ritchie AM, Gilden DH, Borgoon MP, Becker D, Bennet JL (2007) Measles virus-specific plasma cells are prominent in subacute sclerosing panencephalitis CSF. Neurology 68:1815–1819PubMedPubMedCentralCrossRef Owens GP, Ritchie AM, Gilden DH, Borgoon MP, Becker D, Bennet JL (2007) Measles virus-specific plasma cells are prominent in subacute sclerosing panencephalitis CSF. Neurology 68:1815–1819PubMedPubMedCentralCrossRef
233.
Zurück zum Zitat Schönberger K, Ludwig MS, Wildner M, Weissbrich B (2013) Epidemiology of subacute sclerosing panencephalitis (SSPE) in Germany from 2003 to 2009: a risk estimation. PLoS One 2013 Jul 9;8(7) Schönberger K, Ludwig MS, Wildner M, Weissbrich B (2013) Epidemiology of subacute sclerosing panencephalitis (SSPE) in Germany from 2003 to 2009: a risk estimation. PLoS One 2013 Jul 9;8(7)
234.
Zurück zum Zitat Schwab N, Schneider-Hohendorf T, Posevitz V et al (2013) L-Selectin is a possible biomarker for individual PML risk in natalizumab-treated MS patients. Neurology 81:865–871PubMedCrossRef Schwab N, Schneider-Hohendorf T, Posevitz V et al (2013) L-Selectin is a possible biomarker for individual PML risk in natalizumab-treated MS patients. Neurology 81:865–871PubMedCrossRef
235.
Zurück zum Zitat Sharma S, Kumar S (2010) Case report: Cervical spinal cord signal changes in a case of adult-onset subacute sclerosing panencephalitis. Indian J Radiol Imaging 20:202–204PubMedPubMedCentralCrossRef Sharma S, Kumar S (2010) Case report: Cervical spinal cord signal changes in a case of adult-onset subacute sclerosing panencephalitis. Indian J Radiol Imaging 20:202–204PubMedPubMedCentralCrossRef
236.
Zurück zum Zitat Simpson DM (2011) HIV-associated PML: Changing epidemiology and clinical approach. Cleve Clin J Med 78:24–27CrossRef Simpson DM (2011) HIV-associated PML: Changing epidemiology and clinical approach. Cleve Clin J Med 78:24–27CrossRef
237.
Zurück zum Zitat Tatli B, Ekici B, Ozmen M (2010) Flurpirtine may Stopp the progressive course of subacute sclerosing panencephalitis. Med Hypotheses 75:576–577PubMedCrossRef Tatli B, Ekici B, Ozmen M (2010) Flurpirtine may Stopp the progressive course of subacute sclerosing panencephalitis. Med Hypotheses 75:576–577PubMedCrossRef
238.
Zurück zum Zitat Warnke C, Menge T, Hartung HP, Racke MK, Cravens PD, Bennett JL, Frohman EM, Greenberg BM, Zamvil SS, Gold R, Hemmer B, Kieseier BC, Stüve O (2010) Natalizumab and progressive multifocal leukencephalopathy: what are the causal factors and can it be avoided? Arch Neurol 67:923–930PubMedPubMedCentralCrossRef Warnke C, Menge T, Hartung HP, Racke MK, Cravens PD, Bennett JL, Frohman EM, Greenberg BM, Zamvil SS, Gold R, Hemmer B, Kieseier BC, Stüve O (2010) Natalizumab and progressive multifocal leukencephalopathy: what are the causal factors and can it be avoided? Arch Neurol 67:923–930PubMedPubMedCentralCrossRef
239.
Zurück zum Zitat Warnke C, von Geldern G, Markwerth P, et al. (2014) Cerebrospinal Fluid JC Virus Antibody Index for Diagnosis of Natalizumab-Associated Progressive Multifocal Leukoencephalopathy. Ann Neurol 2014, Apr 11 (epub ahead of print) Warnke C, von Geldern G, Markwerth P, et al. (2014) Cerebrospinal Fluid JC Virus Antibody Index for Diagnosis of Natalizumab-Associated Progressive Multifocal Leukoencephalopathy. Ann Neurol 2014, Apr 11 (epub ahead of print)
240.
Zurück zum Zitat Wattjes MP, Vennegoor A, Moster J, van Oosten BW, Barkhof F, Killestein J (2014) Diagnosis of asymptomatic natalizumab-associated PML: are we between a rock and a hard place? J Neurol 261:1139PubMedCrossRef Wattjes MP, Vennegoor A, Moster J, van Oosten BW, Barkhof F, Killestein J (2014) Diagnosis of asymptomatic natalizumab-associated PML: are we between a rock and a hard place? J Neurol 261:1139PubMedCrossRef
242.
Zurück zum Zitat Yilmaz C, Caksen H, Yilmaz N, Güven HS, Bayram I (2007) Two cases of Subacute Sclerosing Panencephalitis associated with Brainstem involvement. Trop Pediatr 53:280–283CrossRef Yilmaz C, Caksen H, Yilmaz N, Güven HS, Bayram I (2007) Two cases of Subacute Sclerosing Panencephalitis associated with Brainstem involvement. Trop Pediatr 53:280–283CrossRef
243.
Zurück zum Zitat Yousry TA, Pelletier D, Cadavid D et al (2012) MRI pattern in natalizumab-associated progressive multifocal leukencephalopathy. Ann Neurol 72:779–787PubMedCrossRef Yousry TA, Pelletier D, Cadavid D et al (2012) MRI pattern in natalizumab-associated progressive multifocal leukencephalopathy. Ann Neurol 72:779–787PubMedCrossRef
244.
Zurück zum Zitat Anduze-Faris BM, Fillet AM, Gozlan J, Lancar R, Boukli N, Gasnault J, Caumes E, Livartowsky J, Matheron S, Leport C, Salmon D, Costagliola D, Katlama C (2000) Induction and maintenance therapy of cytomegalovirus central nervous system infection in HIV-infected patients. Aids 14:517–524PubMedCrossRef Anduze-Faris BM, Fillet AM, Gozlan J, Lancar R, Boukli N, Gasnault J, Caumes E, Livartowsky J, Matheron S, Leport C, Salmon D, Costagliola D, Katlama C (2000) Induction and maintenance therapy of cytomegalovirus central nervous system infection in HIV-infected patients. Aids 14:517–524PubMedCrossRef
245.
Zurück zum Zitat Arendt G (2013) Neurologische Komplikationen der HIV-Infektion in der Ära antiretroviraler Kombinationstherapien (cART). Retroviren Bulletin 1:2013 Arendt G (2013) Neurologische Komplikationen der HIV-Infektion in der Ära antiretroviraler Kombinationstherapien (cART). Retroviren Bulletin 1:2013
246.
Zurück zum Zitat Babiker AG, Emery S, Fätkenheuer G, Gordin FM, Grund B, Lundgren JD, Neaton JD, Pett SL, Phillips A, Touloumi G et al (2013) Considerations in the rationale, design and methods of the Strategic Timing of AntiRetroviral Treatment (START) study. Clin Trials 10(1):5–S36CrossRef Babiker AG, Emery S, Fätkenheuer G, Gordin FM, Grund B, Lundgren JD, Neaton JD, Pett SL, Phillips A, Touloumi G et al (2013) Considerations in the rationale, design and methods of the Strategic Timing of AntiRetroviral Treatment (START) study. Clin Trials 10(1):5–S36CrossRef
247.
Zurück zum Zitat Bucher HC, Griffith L, Guyatt GH, Opravil M (1997) Meta-analysis of prophylactic treatments againts pneumocystis carinii and toxoplasma encephalitis. J Acquir Immune Defic Syndr Hum Retrovirol 15:104–114PubMedCrossRef Bucher HC, Griffith L, Guyatt GH, Opravil M (1997) Meta-analysis of prophylactic treatments againts pneumocystis carinii and toxoplasma encephalitis. J Acquir Immune Defic Syndr Hum Retrovirol 15:104–114PubMedCrossRef
248.
Zurück zum Zitat Cardo DM, Culver DH, Ciesielsky CA, Srivastava PU, Marcus R, Abiteboul D, Heptonstall J, Ippolito G, Lot F, McKibben PS, Bell DM (1997) A case-control study of HIVseroconversion in health care workers after percutaneous exposure. Centers for Disease Control and Prevention Needlestick Surveillance Group. N Engl J Med 337:1485–1490PubMedCrossRef Cardo DM, Culver DH, Ciesielsky CA, Srivastava PU, Marcus R, Abiteboul D, Heptonstall J, Ippolito G, Lot F, McKibben PS, Bell DM (1997) A case-control study of HIVseroconversion in health care workers after percutaneous exposure. Centers for Disease Control and Prevention Needlestick Surveillance Group. N Engl J Med 337:1485–1490PubMedCrossRef
249.
Zurück zum Zitat Centers for Disease Control (1992) 1993 revised classification system for HIV infection and expanded surveillance case definition for AIDS among adolescents and adults. Morbidity and Mortality Weekly Report 41 (RR-17): 1–19 Centers for Disease Control (1992) 1993 revised classification system for HIV infection and expanded surveillance case definition for AIDS among adolescents and adults. Morbidity and Mortality Weekly Report 41 (RR-17): 1–19
250.
Zurück zum Zitat Chaisson RE, Keruly JC, Moore RD (2000) Association of initial CD4 cell count and viral load with response to highly active antiretroviral therapy. J Am Med Assoc 248:3128–3129CrossRef Chaisson RE, Keruly JC, Moore RD (2000) Association of initial CD4 cell count and viral load with response to highly active antiretroviral therapy. J Am Med Assoc 248:3128–3129CrossRef
251.
Zurück zum Zitat Dworkin MS, Wan PC, Hanson DL, Jones JL (1999) Progressive multifocal leucoencephalopathy: improved survival of human immunodeficiency virus-infected patients in the protease inhibitor era. J Infect Dis 180:621–625PubMedCrossRef Dworkin MS, Wan PC, Hanson DL, Jones JL (1999) Progressive multifocal leucoencephalopathy: improved survival of human immunodeficiency virus-infected patients in the protease inhibitor era. J Infect Dis 180:621–625PubMedCrossRef
252.
Zurück zum Zitat Henderson DK (1999) Postexposure chemoprophylaxis for occupational exposures to the human immunodeficiency virus. J Am Med Assoc 281:931–936CrossRef Henderson DK (1999) Postexposure chemoprophylaxis for occupational exposures to the human immunodeficiency virus. J Am Med Assoc 281:931–936CrossRef
253.
Zurück zum Zitat Hoffmann C, Rockstroh JK, Kamps BS (Hrsg) (2007) HIV.Net 2007. www.hiv.net. Steinhäuser, Wuppertal-Beyenburg Hoffmann C, Rockstroh JK, Kamps BS (Hrsg) (2007) HIV.Net 2007. www.hiv.net. Steinhäuser, Wuppertal-Beyenburg
254.
Zurück zum Zitat Joint United Nations Programme on HIV/AIDS (UNAIDS) and World Health Organization (2010) UNAIDS Report on the global AIDS Epidemic 2010 Joint United Nations Programme on HIV/AIDS (UNAIDS) and World Health Organization (2010) UNAIDS Report on the global AIDS Epidemic 2010
255.
Zurück zum Zitat Letendre S, Marquie-Beck J, Capparelli E, Best B, Clifford D, Collier AC, Gelman BB, McArthur JC, McCutchan JA, Morgello S et al (2008) Validation of the CNS Penetration-Effectiveness rank for quantifying antiretroviral penetration into the central nervous system. Arch Neurol 65:65–70PubMedPubMedCentralCrossRef Letendre S, Marquie-Beck J, Capparelli E, Best B, Clifford D, Collier AC, Gelman BB, McArthur JC, McCutchan JA, Morgello S et al (2008) Validation of the CNS Penetration-Effectiveness rank for quantifying antiretroviral penetration into the central nervous system. Arch Neurol 65:65–70PubMedPubMedCentralCrossRef
256.
Zurück zum Zitat Louie M, Markowitz M (2002) Goals and milestones during treatment of HIV-1 infection with antiretroviral therapy: a pathogenesis-based perspective. Antiviral Res 55:15–25PubMedCrossRef Louie M, Markowitz M (2002) Goals and milestones during treatment of HIV-1 infection with antiretroviral therapy: a pathogenesis-based perspective. Antiviral Res 55:15–25PubMedCrossRef
257.
Zurück zum Zitat Mellors JW, Rinaldo CRJ, Gupta P, White RM, Todd JA, Kingsley LA (1996) Prognosis in HIV-1 infection predicted by the quantity of virus in plasma. Science 272:1167–1170PubMedCrossRef Mellors JW, Rinaldo CRJ, Gupta P, White RM, Todd JA, Kingsley LA (1996) Prognosis in HIV-1 infection predicted by the quantity of virus in plasma. Science 272:1167–1170PubMedCrossRef
258.
Zurück zum Zitat Panel on Antiretroviral Guidelines for Adult and Adolescents (2006) Guidelines for the use of antiretroviral agents in HIV-infected adults and adolescents. Department of Health and Human Services. October 10, 2006: 1–113 Panel on Antiretroviral Guidelines for Adult and Adolescents (2006) Guidelines for the use of antiretroviral agents in HIV-infected adults and adolescents. Department of Health and Human Services. October 10, 2006: 1–113
259.
Zurück zum Zitat Portegies P, Solod L, Cinque P, Chaudhuri A, Begovac J, Everall I, Weber T, Bojar M, Martinez-Martin P, Kennedy PG (2004) Guidelines for the diagnosis and management of neurological complications of HIV infection. Eur J Neurol 11:297–304PubMedCrossRef Portegies P, Solod L, Cinque P, Chaudhuri A, Begovac J, Everall I, Weber T, Bojar M, Martinez-Martin P, Kennedy PG (2004) Guidelines for the diagnosis and management of neurological complications of HIV infection. Eur J Neurol 11:297–304PubMedCrossRef
260.
Zurück zum Zitat Saag MS, Graybill RJ, Larsen RA, Pappas PG, Perfect JR, Powderly WG, Sobel JD, Dismukes WE (2000) Practice guidelines for the management of cryptococcal disease. Infectious diseases Society of America. Clin Infect Dis 30:710–718PubMedCrossRef Saag MS, Graybill RJ, Larsen RA, Pappas PG, Perfect JR, Powderly WG, Sobel JD, Dismukes WE (2000) Practice guidelines for the management of cryptococcal disease. Infectious diseases Society of America. Clin Infect Dis 30:710–718PubMedCrossRef
261.
Zurück zum Zitat Sackto N, McArthur JC (1997) Prospects for therapy of HIV-associated neurologic diseases. J Neurovirol 3:89–101CrossRef Sackto N, McArthur JC (1997) Prospects for therapy of HIV-associated neurologic diseases. J Neurovirol 3:89–101CrossRef
262.
Zurück zum Zitat Schabet M, Herrlinger U, Weller M, Bamberg M, Clemens R, Dichgans J (1997) Neue Entwicklungen in Diagnostik und Therapie primärer Non-Hodgkin-Lymphome des zentralen Nervensystems. Nervenarzt 68:298–308PubMedCrossRef Schabet M, Herrlinger U, Weller M, Bamberg M, Clemens R, Dichgans J (1997) Neue Entwicklungen in Diagnostik und Therapie primärer Non-Hodgkin-Lymphome des zentralen Nervensystems. Nervenarzt 68:298–308PubMedCrossRef
263.
Zurück zum Zitat Wildemann B, Haas J, Lynen N, Stingele K, Storch-Hagenlocher B (1998) Diagnosis of cytomegalovirus encephalitis in patients with AIDS by quantitation of cytomegalovirus genomes in cells of cerebrospinal fluid. Neurology 50:693–697PubMedCrossRef Wildemann B, Haas J, Lynen N, Stingele K, Storch-Hagenlocher B (1998) Diagnosis of cytomegalovirus encephalitis in patients with AIDS by quantitation of cytomegalovirus genomes in cells of cerebrospinal fluid. Neurology 50:693–697PubMedCrossRef
270.
Zurück zum Zitat Balasegaram M, Harris S, Checchi F et al (2006) Melarsoprol versus eflornithine for treating late-stage Gambian trypanosomiasis in the Republic of the Congo. Bulletin WHO 84:783–791 Balasegaram M, Harris S, Checchi F et al (2006) Melarsoprol versus eflornithine for treating late-stage Gambian trypanosomiasis in the Republic of the Congo. Bulletin WHO 84:783–791
271.
Zurück zum Zitat Birbeck GL, Beare N, Lewallen S et al (2010) Identification of malaria retinopathy improves the specificity of the clinical diagnosis of cerebral malaria: findings from a prospective cohort study. Am J Trop Med Hyg 82:231–234PubMedPubMedCentralCrossRef Birbeck GL, Beare N, Lewallen S et al (2010) Identification of malaria retinopathy improves the specificity of the clinical diagnosis of cerebral malaria: findings from a prospective cohort study. Am J Trop Med Hyg 82:231–234PubMedPubMedCentralCrossRef
272.
Zurück zum Zitat Birbeck GL, Molyneux ME, Kaplan PW et al (2010) Blantyre Malaria Project Epilepsy Study (BMPES) of neurological outcomes in retinopathy-positive paediatric cerebral malaria survivors: a prospective cohort study. Lancet Neurol 9:1173–1181PubMedPubMedCentralCrossRef Birbeck GL, Molyneux ME, Kaplan PW et al (2010) Blantyre Malaria Project Epilepsy Study (BMPES) of neurological outcomes in retinopathy-positive paediatric cerebral malaria survivors: a prospective cohort study. Lancet Neurol 9:1173–1181PubMedPubMedCentralCrossRef
273.
Zurück zum Zitat Braakman H, Fred MM, van de Molengraft JJ et al (2006) Lethal African trypanosomiasis in a traveler: MRI and neuropathology. Neurology 66:1094–1096PubMedCrossRef Braakman H, Fred MM, van de Molengraft JJ et al (2006) Lethal African trypanosomiasis in a traveler: MRI and neuropathology. Neurology 66:1094–1096PubMedCrossRef
274.
Zurück zum Zitat Burgos JM, Begher S, Silva HM et al (2008) Molecular identification of Trypanosoma cruzi I tropism for central nervous system in Chagas reactivation due to AIDS. Am J Trop Med Hyg 78:294–297PubMed Burgos JM, Begher S, Silva HM et al (2008) Molecular identification of Trypanosoma cruzi I tropism for central nervous system in Chagas reactivation due to AIDS. Am J Trop Med Hyg 78:294–297PubMed
275.
Zurück zum Zitat Carod-Artal FJ (2009) Tropical causes of epilepsy. Rev Neurol 49:475–482PubMed Carod-Artal FJ (2009) Tropical causes of epilepsy. Rev Neurol 49:475–482PubMed
276.
Zurück zum Zitat Chacko G (2010) Parasitic diseases of the central nervous system. Semin Diagn Pathol 27:167–185PubMedCrossRef Chacko G (2010) Parasitic diseases of the central nervous system. Semin Diagn Pathol 27:167–185PubMedCrossRef
277.
Zurück zum Zitat Córdova E, Maiolo E, Corti M, Orduna T (2010) Neurological manifestations of Chagas’ disease. Neurol Res 32:238–244PubMedCrossRef Córdova E, Maiolo E, Corti M, Orduna T (2010) Neurological manifestations of Chagas’ disease. Neurol Res 32:238–244PubMedCrossRef
278.
Zurück zum Zitat Corpelet C, Vacher P, Coudore F et al (2005) Role of quinine in life-threatening Babesia divergens infection successfully treated with clindamycin. Eur J Clin Microbiol Infect Dis 24:74–75PubMedCrossRef Corpelet C, Vacher P, Coudore F et al (2005) Role of quinine in life-threatening Babesia divergens infection successfully treated with clindamycin. Eur J Clin Microbiol Infect Dis 24:74–75PubMedCrossRef
279.
Zurück zum Zitat Dauriac-Le Masson V, Chochon F, Demeret S et al (2005) Toxocara canis meningomyelitis. J Neurol 252:1267–1268PubMedCrossRef Dauriac-Le Masson V, Chochon F, Demeret S et al (2005) Toxocara canis meningomyelitis. J Neurol 252:1267–1268PubMedCrossRef
280.
Zurück zum Zitat Davis TME, White NJ, Looareesuwan S, Silamut K, Warrell DA (1988) Quinine pharmacokinetics in cerebral malaria: predicted plasma concentrations after rapid intravenous loading using a two compartment mode. Trans R Soc Trop Med Hyg 82:542–547PubMedCrossRef Davis TME, White NJ, Looareesuwan S, Silamut K, Warrell DA (1988) Quinine pharmacokinetics in cerebral malaria: predicted plasma concentrations after rapid intravenous loading using a two compartment mode. Trans R Soc Trop Med Hyg 82:542–547PubMedCrossRef
281.
Zurück zum Zitat Del Brutto OH, Roos KL, Coffey CS et al (2006) Meta-Analysis: Cysticidal Drugs for Neurocysticercosis: Albendazole and Praziquantel. Ann Intern Med 145:43–51PubMedCrossRef Del Brutto OH, Roos KL, Coffey CS et al (2006) Meta-Analysis: Cysticidal Drugs for Neurocysticercosis: Albendazole and Praziquantel. Ann Intern Med 145:43–51PubMedCrossRef
282.
Zurück zum Zitat Deo I, Robledo L, Meza A et al (2000) Encephalitis due to a free-living amoeba (Balamuthia mandrillaris), case report with literature review. Surg Neurol 53:611–616CrossRef Deo I, Robledo L, Meza A et al (2000) Encephalitis due to a free-living amoeba (Balamuthia mandrillaris), case report with literature review. Surg Neurol 53:611–616CrossRef
283.
Zurück zum Zitat Dondorp AM, Fanello CI, Hendriksen IC et al (2010) Artesunate versus quinine in the treatment of severe falciparum malaria in African children (AQUAMAT): an open-label, randomized trial. Lancet 376:1647–1657PubMedPubMedCentralCrossRef Dondorp AM, Fanello CI, Hendriksen IC et al (2010) Artesunate versus quinine in the treatment of severe falciparum malaria in African children (AQUAMAT): an open-label, randomized trial. Lancet 376:1647–1657PubMedPubMedCentralCrossRef
284.
Zurück zum Zitat Dondorp A, Nosten F, Stepniewska K et al (2005) Artesunate versus quinine for treatment of severe falciparum malaria: a randomised trial. Lancet 366:717–725PubMedCrossRef Dondorp A, Nosten F, Stepniewska K et al (2005) Artesunate versus quinine for treatment of severe falciparum malaria: a randomised trial. Lancet 366:717–725PubMedCrossRef
285.
Zurück zum Zitat Ellrodt A, Halfon P, Le Bras P, Halimi P, Bouree P, Desi M, Caquet R (1987) Multifocal central nervous system lesions in three patients with trichinosis. Arch Neurol 44:432–434PubMedCrossRef Ellrodt A, Halfon P, Le Bras P, Halimi P, Bouree P, Desi M, Caquet R (1987) Multifocal central nervous system lesions in three patients with trichinosis. Arch Neurol 44:432–434PubMedCrossRef
287.
Zurück zum Zitat Elsheikha HM, Khan NA (2010) Protozoa traversal of the blood-brain barrier to invade the central nervous system. FEMS Microbiol 34:532–553CrossRef Elsheikha HM, Khan NA (2010) Protozoa traversal of the blood-brain barrier to invade the central nervous system. FEMS Microbiol 34:532–553CrossRef
289.
Zurück zum Zitat Feely NM, Waghorn DJ, Dexter T, Gallen I, Chioidini P (2010) Strongyloides stercoralis hyperinfection: difficulties in diagnosis and treatment. Anaesthesia 65:298–301PubMedCrossRef Feely NM, Waghorn DJ, Dexter T, Gallen I, Chioidini P (2010) Strongyloides stercoralis hyperinfection: difficulties in diagnosis and treatment. Anaesthesia 65:298–301PubMedCrossRef
290.
Zurück zum Zitat Garcia HH, Pretell EJ, Gilman RH et al (2004) A trial of antiparasitic treatment to reduce the rate of seizures due to cerebral cysticercosis. N Engl J Med 350:249–258PubMedCrossRef Garcia HH, Pretell EJ, Gilman RH et al (2004) A trial of antiparasitic treatment to reduce the rate of seizures due to cerebral cysticercosis. N Engl J Med 350:249–258PubMedCrossRef
291.
Zurück zum Zitat Golenser J, McQuillain J, Hee L et al (2006) Conventional and experimental treatment of cerebral malaria. Internat J Parasitol 36:583–593CrossRef Golenser J, McQuillain J, Hee L et al (2006) Conventional and experimental treatment of cerebral malaria. Internat J Parasitol 36:583–593CrossRef
292.
Zurück zum Zitat Hainard A, Tiberti N, Robin X et al (2011) Matrix metalloproteinase-9 and intercellulara adhesion molecule 1 are powerful staging markers for human African Trypanosomiasis. Trop Med Int Health 16:119–126PubMedCrossRef Hainard A, Tiberti N, Robin X et al (2011) Matrix metalloproteinase-9 and intercellulara adhesion molecule 1 are powerful staging markers for human African Trypanosomiasis. Trop Med Int Health 16:119–126PubMedCrossRef
293.
Zurück zum Zitat Helbok R, Brenneis C, Beer R et al (2007) A rare case of Toxocara canis cerebral vasculitis. Europ J Neurol 14:117–120CrossRef Helbok R, Brenneis C, Beer R et al (2007) A rare case of Toxocara canis cerebral vasculitis. Europ J Neurol 14:117–120CrossRef
295.
Zurück zum Zitat Häselbarth K, Tenter AM, Brade V et al (2007) First case of human babesiosis in Germany – Clinical presentation and molecular characterisation of the pathogen. Internat J Med Microbiol 297:197–204CrossRef Häselbarth K, Tenter AM, Brade V et al (2007) First case of human babesiosis in Germany – Clinical presentation and molecular characterisation of the pathogen. Internat J Med Microbiol 297:197–204CrossRef
296.
297.
Zurück zum Zitat Katchanov J, Nawa Y (2010) Helminthic invasion of the central nervous system: many roads lead to Rome. Parasitol Int 59:491–496PubMedCrossRef Katchanov J, Nawa Y (2010) Helminthic invasion of the central nervous system: many roads lead to Rome. Parasitol Int 59:491–496PubMedCrossRef
299.
Zurück zum Zitat Krishnan A, Karnad DR (2003) Severe falciparum malaria: an important cause of multiple organ failure in Indian intensive care unit patients. Crit Care Med 31:2278–2284PubMedCrossRef Krishnan A, Karnad DR (2003) Severe falciparum malaria: an important cause of multiple organ failure in Indian intensive care unit patients. Crit Care Med 31:2278–2284PubMedCrossRef
300.
Zurück zum Zitat Khan NA (2010) Novel in vitro and in vivo models to study central nervous system infections due to Acanthamoeba spp. Exp Parasitol 126:69–72PubMedCrossRef Khan NA (2010) Novel in vitro and in vivo models to study central nervous system infections due to Acanthamoeba spp. Exp Parasitol 126:69–72PubMedCrossRef
301.
Zurück zum Zitat Kristensson K, Nygard M, Bertini G, Bentivoglio (2010) African trypanosome infections of the nervous system: parasite entry and effects on sleep and synaptic functions. Prog Neurobiol 91:152–171PubMedCrossRef Kristensson K, Nygard M, Bertini G, Bentivoglio (2010) African trypanosome infections of the nervous system: parasite entry and effects on sleep and synaptic functions. Prog Neurobiol 91:152–171PubMedCrossRef
302.
Zurück zum Zitat Lackner P, Beer R, Broessner G et al (2010) Acute granulomatous acanthamoeba encephalitis in an immunocompetent patient. Neurocrit Care 12:91–94PubMedCrossRef Lackner P, Beer R, Broessner G et al (2010) Acute granulomatous acanthamoeba encephalitis in an immunocompetent patient. Neurocrit Care 12:91–94PubMedCrossRef
303.
305.
Zurück zum Zitat Lv S, Zhang Y, Steinmann P, Utzinger J (2010) Helminth infections of the central nervous system occurring in Southeast Asia and the Far East. Adv Parasitol 72:351–408PubMedCrossRef Lv S, Zhang Y, Steinmann P, Utzinger J (2010) Helminth infections of the central nervous system occurring in Southeast Asia and the Far East. Adv Parasitol 72:351–408PubMedCrossRef
306.
Zurück zum Zitat Mace SE (2010) Central nervous system infections as a cause of an altered mental status? What is the pathogen growing in your central nervous system? Emerg Med Clin North Am 28:535–570PubMedCrossRef Mace SE (2010) Central nervous system infections as a cause of an altered mental status? What is the pathogen growing in your central nervous system? Emerg Med Clin North Am 28:535–570PubMedCrossRef
307.
Zurück zum Zitat Marr JJ, Docampo R (1986) Chemotherapy for Chagas’ disease: a perspective of current therapy and considerations for future research. Rev Infect Dis 8:884–903PubMedCrossRef Marr JJ, Docampo R (1986) Chemotherapy for Chagas’ disease: a perspective of current therapy and considerations for future research. Rev Infect Dis 8:884–903PubMedCrossRef
308.
Zurück zum Zitat Michal A, Regli F, Campiche R, Cavallo RJ, de Crousaz G, Oberson R, Rabinowicz T (1977) Cerebral coenurosis. Report of a case with arteritis. J Neurol 216:265–272PubMedCrossRef Michal A, Regli F, Campiche R, Cavallo RJ, de Crousaz G, Oberson R, Rabinowicz T (1977) Cerebral coenurosis. Report of a case with arteritis. J Neurol 216:265–272PubMedCrossRef
309.
Zurück zum Zitat Michelet L, Fleury A, Sciutto E et al (2011) Human neurocysticercosis: Comparision of different diagnostic tests in cerebrospinal fluid. J Clin Microbiol 49:195–200PubMedCrossRef Michelet L, Fleury A, Sciutto E et al (2011) Human neurocysticercosis: Comparision of different diagnostic tests in cerebrospinal fluid. J Clin Microbiol 49:195–200PubMedCrossRef
310.
Zurück zum Zitat Molyneux ME, Taylor TE, Wirima JJ, Borgstein A (1989) Clinical features and prognostic indicators in paediatric cerebral malaria: a study of 131 comatose Malawian children. O J Med 71:441–459 Molyneux ME, Taylor TE, Wirima JJ, Borgstein A (1989) Clinical features and prognostic indicators in paediatric cerebral malaria: a study of 131 comatose Malawian children. O J Med 71:441–459
311.
Zurück zum Zitat Nanda NC, Rath P, Acharya J, Mishra P, Mishra SK (2011) Falciparum Malaria in Children-A Brief Report of 305 Patients from Rourkela, Eastern India. Indian J Pediatr 78:475–477PubMedCrossRef Nanda NC, Rath P, Acharya J, Mishra P, Mishra SK (2011) Falciparum Malaria in Children-A Brief Report of 305 Patients from Rourkela, Eastern India. Indian J Pediatr 78:475–477PubMedCrossRef
312.
Zurück zum Zitat Nkouawa A, Sako Y, Itoh S et al (2010) Serological studies of neurologic helminthic infections in rural areas of southwest Cameroon: toxocariasis, cysticercosis and paragonimiasis. PLoS Negl Trop Dis 4:e732PubMedPubMedCentralCrossRef Nkouawa A, Sako Y, Itoh S et al (2010) Serological studies of neurologic helminthic infections in rural areas of southwest Cameroon: toxocariasis, cysticercosis and paragonimiasis. PLoS Negl Trop Dis 4:e732PubMedPubMedCentralCrossRef
313.
Zurück zum Zitat Onyeyili PA, Onwualu JE (1991) Efficacy of combination of DFMO and diminazene aceturate in the treatment of late-stage Trypanosoma brucei infection in rats. Trop Med Parasitol 42:143–145PubMed Onyeyili PA, Onwualu JE (1991) Efficacy of combination of DFMO and diminazene aceturate in the treatment of late-stage Trypanosoma brucei infection in rats. Trop Med Parasitol 42:143–145PubMed
314.
Zurück zum Zitat Pitella JEH (1984) Ischemic cerebral changes in the chronic chagasic cardiopathy. Arq Neuropsiquiatr 42:105–115PubMedCrossRef Pitella JEH (1984) Ischemic cerebral changes in the chronic chagasic cardiopathy. Arq Neuropsiquiatr 42:105–115PubMedCrossRef
315.
Zurück zum Zitat Poltera AA (1985) Pathology of human African trypanosomiasis with reference to experimental African trypanosomiasis and infections of the central nervous system. Br Med Bull 41:169–174PubMed Poltera AA (1985) Pathology of human African trypanosomiasis with reference to experimental African trypanosomiasis and infections of the central nervous system. Br Med Bull 41:169–174PubMed
316.
Zurück zum Zitat Potchen MJ, Birbeck GL, Demarco JK et al (2010) Neuroimaging findings in children with retinopathy-confirmed cerebral malaria. Eur J Radiol 74:262–268PubMedCrossRef Potchen MJ, Birbeck GL, Demarco JK et al (2010) Neuroimaging findings in children with retinopathy-confirmed cerebral malaria. Eur J Radiol 74:262–268PubMedCrossRef
318.
Zurück zum Zitat Saddler M, Barry M, Ternouth I, Emmanuel J (1990) Treatment of severe malaria by exchange transfusion. N Engl J Med 322:58CrossRef Saddler M, Barry M, Ternouth I, Emmanuel J (1990) Treatment of severe malaria by exchange transfusion. N Engl J Med 322:58CrossRef
319.
Zurück zum Zitat Saleem T, Rabbani M, Jamil B (2009) Primary amoebic meningoencephalitis: two new cases from Pakistan. Trop Doct 39:242–243PubMedCrossRef Saleem T, Rabbani M, Jamil B (2009) Primary amoebic meningoencephalitis: two new cases from Pakistan. Trop Doct 39:242–243PubMedCrossRef
320.
Zurück zum Zitat Sattar MA, Hoque HW, Amin MR, Faiz MA, Rahman MR (2009) Neurological findings and outcome in adult cerebral malaria. Bangladesh Med Res Counc Bull 35:15–17PubMedCrossRef Sattar MA, Hoque HW, Amin MR, Faiz MA, Rahman MR (2009) Neurological findings and outcome in adult cerebral malaria. Bangladesh Med Res Counc Bull 35:15–17PubMedCrossRef
321.
Zurück zum Zitat Schmutzhard E (2010) Parasitic diseases of the central nervous system. Nervenarzt 81:162–171PubMedCrossRef Schmutzhard E (2010) Parasitic diseases of the central nervous system. Nervenarzt 81:162–171PubMedCrossRef
322.
Zurück zum Zitat Schmutzhard E (2006) Protozoal Infections. In: Noseworthy JH (Hrsg) Neurological Therapeutics – Principles and Practice. Informa Health Care, Abingdon, Oxon, S 1116–1132 Schmutzhard E (2006) Protozoal Infections. In: Noseworthy JH (Hrsg) Neurological Therapeutics – Principles and Practice. Informa Health Care, Abingdon, Oxon, S 1116–1132
323.
Zurück zum Zitat Schmutzhard E, Mayr U, Rumpl E, Prugger M, Pohl P (1986) Secondary cerebral amebiasis due to infection with Entamoeba histolytica. Eur Neurol 25:161–165PubMedCrossRef Schmutzhard E, Mayr U, Rumpl E, Prugger M, Pohl P (1986) Secondary cerebral amebiasis due to infection with Entamoeba histolytica. Eur Neurol 25:161–165PubMedCrossRef
324.
Zurück zum Zitat Schmutzhard E, Boongird P, Vejjajiva A (1988) Eosinophilic meningitis and radiculomyelitis in Thailand, caused by CNS invasion of Gnathostoma spingerum and Angiostrongylus cantonensis. J Neurol Neurosurg Psychiatry 51:80–87PubMedPubMedCentralCrossRef Schmutzhard E, Boongird P, Vejjajiva A (1988) Eosinophilic meningitis and radiculomyelitis in Thailand, caused by CNS invasion of Gnathostoma spingerum and Angiostrongylus cantonensis. J Neurol Neurosurg Psychiatry 51:80–87PubMedPubMedCentralCrossRef
325.
Zurück zum Zitat Scowden EB, Schaffner W, Stone WJ (1978) Overwhelming strongyloidiasis: an unappreciated opportunistic infection. Medicine (Baltimore) 57:527–544CrossRef Scowden EB, Schaffner W, Stone WJ (1978) Overwhelming strongyloidiasis: an unappreciated opportunistic infection. Medicine (Baltimore) 57:527–544CrossRef
326.
Zurück zum Zitat Silva AA, Roffe E, Santiago H et al (2007) Trypanosoma cruzi-triggered meningoencephalitis is a CCR1/CCR5-independent inflammatory process. J Neuroimmunol 184:156–163PubMedCrossRef Silva AA, Roffe E, Santiago H et al (2007) Trypanosoma cruzi-triggered meningoencephalitis is a CCR1/CCR5-independent inflammatory process. J Neuroimmunol 184:156–163PubMedCrossRef
327.
Zurück zum Zitat Solaymani-Mohammadi S, Lam MM, Zunt JR, Petri WA et al (2007) Entamoeba histolytica encephalitis diagnosed by PCR of cerebral spinal fluid. Trans R Soc Trop Med Hyg 101:311–313PubMedCrossRef Solaymani-Mohammadi S, Lam MM, Zunt JR, Petri WA et al (2007) Entamoeba histolytica encephalitis diagnosed by PCR of cerebral spinal fluid. Trans R Soc Trop Med Hyg 101:311–313PubMedCrossRef
328.
Zurück zum Zitat Sotelo-Avila C (1987) Naegleria and Acanthamoeba. Free-living amebas pathogenic for man. Perspect Pediatr Pathol 10:51–58PubMed Sotelo-Avila C (1987) Naegleria and Acanthamoeba. Free-living amebas pathogenic for man. Perspect Pediatr Pathol 10:51–58PubMed
329.
Zurück zum Zitat Taelman H, Schaechter PJ, Marcelis L (1987) Difluoromethylornithine, an effective new treatment of Gambian trypanosomiasis. Am J Med 82:607–614PubMedCrossRef Taelman H, Schaechter PJ, Marcelis L (1987) Difluoromethylornithine, an effective new treatment of Gambian trypanosomiasis. Am J Med 82:607–614PubMedCrossRef
330.
Zurück zum Zitat Tran TH, Dolecek C, Pham PM et al (2004) Dihydroartemisinin-piperaquine against multidrug-resistant Plasmodium falciparum malaria in Vietnam: randomised clinical trial. Lancet 363:18–22PubMedCrossRef Tran TH, Dolecek C, Pham PM et al (2004) Dihydroartemisinin-piperaquine against multidrug-resistant Plasmodium falciparum malaria in Vietnam: randomised clinical trial. Lancet 363:18–22PubMedCrossRef
331.
Zurück zum Zitat Urbina JA, Docampo R (2003) Specific chemotherapy of Chagas disease: controversies and advances. Trends Parasiotol 11:495–501CrossRef Urbina JA, Docampo R (2003) Specific chemotherapy of Chagas disease: controversies and advances. Trends Parasiotol 11:495–501CrossRef
332.
Zurück zum Zitat Utzinger J, Bergquist R, Olveda R, Zhou XN (2010) Important helminth infections in Southeast Asia diversity, potential for control and prospects for elimination. Adv Parasitol 72:1–30PubMedCrossRef Utzinger J, Bergquist R, Olveda R, Zhou XN (2010) Important helminth infections in Southeast Asia diversity, potential for control and prospects for elimination. Adv Parasitol 72:1–30PubMedCrossRef
333.
Zurück zum Zitat Visvesvara GS (2010) Amebic meningoencephalitides and keratitis: challenges in diagnosis and treatment. Curr Opin Infect Dis 23:590–594PubMedCrossRef Visvesvara GS (2010) Amebic meningoencephalitides and keratitis: challenges in diagnosis and treatment. Curr Opin Infect Dis 23:590–594PubMedCrossRef
334.
Zurück zum Zitat Wang J, Qi H, Diao Z et al (2010) An outbreak of angiostrongyliasis cantonensis in Beijing. J Parasitol 96:377–381PubMedCrossRef Wang J, Qi H, Diao Z et al (2010) An outbreak of angiostrongyliasis cantonensis in Beijing. J Parasitol 96:377–381PubMedCrossRef
335.
Zurück zum Zitat Wang P, Wu MC, Chen SJ et al (2010) Research development of the pathogenesis pathways for neuroschistosomiasis. Neurosci Bull 26:168–174PubMedCrossRef Wang P, Wu MC, Chen SJ et al (2010) Research development of the pathogenesis pathways for neuroschistosomiasis. Neurosci Bull 26:168–174PubMedCrossRef
336.
Zurück zum Zitat Warrell DA, Looareesuwan S, Warrell MJ, Kasemarn P, Intaraprasert R, Bunnag D, Harinasuta T (1982) Dexamethasone proves deleterious in cerebral malaria. A double blind trial in 100 comatose patients. N Engl J Med 306:313–319PubMedCrossRef Warrell DA, Looareesuwan S, Warrell MJ, Kasemarn P, Intaraprasert R, Bunnag D, Harinasuta T (1982) Dexamethasone proves deleterious in cerebral malaria. A double blind trial in 100 comatose patients. N Engl J Med 306:313–319PubMedCrossRef
337.
Zurück zum Zitat Watt G, Long GW, Ranoa CP, Adapon B, Fernando MT, Cross JH (1989) Praziquantel in treatment of cerebral schistosomiasis. Lancet 2:262–263 Watt G, Long GW, Ranoa CP, Adapon B, Fernando MT, Cross JH (1989) Praziquantel in treatment of cerebral schistosomiasis. Lancet 2:262–263
338.
Zurück zum Zitat Wenzler T, Boykin DW, Ismail MA et al (2009) New treatment option for second-stage African sleeping sickness: in vitro and in vivo efficacy of aza analogs of DB289 Antimicrobiob Agents. Chemother 53:4185–4192 Wenzler T, Boykin DW, Ismail MA et al (2009) New treatment option for second-stage African sleeping sickness: in vitro and in vivo efficacy of aza analogs of DB289 Antimicrobiob Agents. Chemother 53:4185–4192
339.
Zurück zum Zitat Winkler AS, Willingham AL 3rd, Sikasunge CS et al (2009) Epilepsy and neurocysticercosis in sub-Saharan Africa. Wien Klin Wochenschr 3:3–12CrossRef Winkler AS, Willingham AL 3rd, Sikasunge CS et al (2009) Epilepsy and neurocysticercosis in sub-Saharan Africa. Wien Klin Wochenschr 3:3–12CrossRef
340.
Zurück zum Zitat Wittner M, Rowin KS, Tanowitz HB et al (1982) Successful chemotherapy of transfusion babesiosis. An Intern Med 96:601–604CrossRef Wittner M, Rowin KS, Tanowitz HB et al (1982) Successful chemotherapy of transfusion babesiosis. An Intern Med 96:601–604CrossRef
341.
Zurück zum Zitat World Health Organization (2000) Managment of Servere Malaria: A practical Handbook, 2. Aufl. World Health Organization, Geneva World Health Organization (2000) Managment of Servere Malaria: A practical Handbook, 2. Aufl. World Health Organization, Geneva
342.
Zurück zum Zitat Zimmerman GA, Castro-Faria-Neto H (2010) Persistent cognitive impairment after cerebral malaria: models, mechanisms and adjunctive therapies. Expert Rev Anti Infect Ther 8:1209–1212PubMedCrossRef Zimmerman GA, Castro-Faria-Neto H (2010) Persistent cognitive impairment after cerebral malaria: models, mechanisms and adjunctive therapies. Expert Rev Anti Infect Ther 8:1209–1212PubMedCrossRef
344.
Zurück zum Zitat Abbott SP et al (1995) Fatal cerebral mycoses caused by the ascomycete Chaetomium strumarium. J Clin Microbiol 33:2692–2698PubMedPubMedCentral Abbott SP et al (1995) Fatal cerebral mycoses caused by the ascomycete Chaetomium strumarium. J Clin Microbiol 33:2692–2698PubMedPubMedCentral
345.
Zurück zum Zitat Al-Jehani H, Guiot MC, Torres C, Marcoux J (2010) Scedosporium cerebral abscesses after extra-corporeal membrane oxygenation. Can J Neurol Sci 37:671–678PubMedCrossRef Al-Jehani H, Guiot MC, Torres C, Marcoux J (2010) Scedosporium cerebral abscesses after extra-corporeal membrane oxygenation. Can J Neurol Sci 37:671–678PubMedCrossRef
346.
Zurück zum Zitat Andreoni SC (2004) Medical Mycology Atlas. S-Systems, Milano Andreoni SC (2004) Medical Mycology Atlas. S-Systems, Milano
347.
Zurück zum Zitat Bennett JE (1987) Rapid diagnosis of candidiasis and aspergillosis. Rev Infect Dis 9:398–402PubMedCrossRef Bennett JE (1987) Rapid diagnosis of candidiasis and aspergillosis. Rev Infect Dis 9:398–402PubMedCrossRef
348.
Zurück zum Zitat Berger JR, Greenberg RN (2010) Isolated central nervous system histoplasmosis in an immunocompetent patient: 53-month hiatus to diagnosis and treatment. J Neurovirol 16:472–474PubMedCrossRef Berger JR, Greenberg RN (2010) Isolated central nervous system histoplasmosis in an immunocompetent patient: 53-month hiatus to diagnosis and treatment. J Neurovirol 16:472–474PubMedCrossRef
349.
Zurück zum Zitat Black KE, Baden LR (2007) Fungal infections of the CNS: treatment strategies for the immunocompromised patient. CNS Drugs 21:293–318PubMedCrossRef Black KE, Baden LR (2007) Fungal infections of the CNS: treatment strategies for the immunocompromised patient. CNS Drugs 21:293–318PubMedCrossRef
350.
Zurück zum Zitat Blyth CC, Hale K, Palasanthiran P, O’Brian T, Bennett HMl (2010) Antifungal therapy in infants and children with proven, probable or suspected invasive fungal infections. Cochrane Database Syst Rev Feb 17:CD006343 Blyth CC, Hale K, Palasanthiran P, O’Brian T, Bennett HMl (2010) Antifungal therapy in infants and children with proven, probable or suspected invasive fungal infections. Cochrane Database Syst Rev Feb 17:CD006343
351.
Zurück zum Zitat Christophe C, Azzi N, Bouche B et al (1999) Magnetic resonance imaging and angiography in cerebral fungal vasculitis. Neuropediatrics 30:218–220PubMedCrossRef Christophe C, Azzi N, Bouche B et al (1999) Magnetic resonance imaging and angiography in cerebral fungal vasculitis. Neuropediatrics 30:218–220PubMedCrossRef
352.
Zurück zum Zitat Cuenca-Estrella M, Gomez-Lopez A, Garcia-Effron G et al (2005) Combined activity in vitro of Caspofungin, amphothericin B, and azole agents against itraconazloe-resistant clinical isolates of Aspergillus fumigatus. Antimicrob Agents Chemother 49:1232–1235PubMedPubMedCentralCrossRef Cuenca-Estrella M, Gomez-Lopez A, Garcia-Effron G et al (2005) Combined activity in vitro of Caspofungin, amphothericin B, and azole agents against itraconazloe-resistant clinical isolates of Aspergillus fumigatus. Antimicrob Agents Chemother 49:1232–1235PubMedPubMedCentralCrossRef
353.
Zurück zum Zitat Diekema DJ, Messer SA, Hollis RJ et al (2003) Activities of caspofungin, itraconazole, posaconazole, ravuconazole, voriconazole, and amphotericin B against 448 recent clinical isolates of filamentous fungi. J Clin Microbiol 41:3623–3626PubMedPubMedCentralCrossRef Diekema DJ, Messer SA, Hollis RJ et al (2003) Activities of caspofungin, itraconazole, posaconazole, ravuconazole, voriconazole, and amphotericin B against 448 recent clinical isolates of filamentous fungi. J Clin Microbiol 41:3623–3626PubMedPubMedCentralCrossRef
354.
Zurück zum Zitat Dupont B (2002) Overview of the lipid formulations of amphotericin B. J Antimicrob Chemother 49:31–36PubMedCrossRef Dupont B (2002) Overview of the lipid formulations of amphotericin B. J Antimicrob Chemother 49:31–36PubMedCrossRef
355.
Zurück zum Zitat Feltracco P, Barbieri S, Furnari M et al (2010) Central nervous system infectious complications early after liver transplantation. Transplant Proc 42:1216–1222PubMedCrossRef Feltracco P, Barbieri S, Furnari M et al (2010) Central nervous system infectious complications early after liver transplantation. Transplant Proc 42:1216–1222PubMedCrossRef
356.
Zurück zum Zitat Fica A, Diaz MC, Luppi M (2003) Unsuccessful treatment with voriconazole of a brain abscess due to Cladophialophora bantiana. Scand J Infect Dis 35:892–893PubMedCrossRef Fica A, Diaz MC, Luppi M (2003) Unsuccessful treatment with voriconazole of a brain abscess due to Cladophialophora bantiana. Scand J Infect Dis 35:892–893PubMedCrossRef
357.
Zurück zum Zitat Friedman JA, Wijdicks EF, Fulgham JR (2000) Meningoencephalitis due to Blastomyces dermatitidis: case report and literature review. Mayo Clin Proc 75:403–408PubMedCrossRef Friedman JA, Wijdicks EF, Fulgham JR (2000) Meningoencephalitis due to Blastomyces dermatitidis: case report and literature review. Mayo Clin Proc 75:403–408PubMedCrossRef
358.
Zurück zum Zitat Garcia RJ, Troya P, Edwards C (2006) Invasive aspergillosis with central nervous system dissemination in a presumably immunocompetent, non-neutropenic patient: case report and review. South Med J 99:607–610PubMedCrossRef Garcia RJ, Troya P, Edwards C (2006) Invasive aspergillosis with central nervous system dissemination in a presumably immunocompetent, non-neutropenic patient: case report and review. South Med J 99:607–610PubMedCrossRef
359.
Zurück zum Zitat Glass HC, Wirrell E, Sarnat HB et al (2007) MRI findings in an immunocompromised boy with CNS fungal infection. Can J Neurol Sci 34:88–91PubMedCrossRef Glass HC, Wirrell E, Sarnat HB et al (2007) MRI findings in an immunocompromised boy with CNS fungal infection. Can J Neurol Sci 34:88–91PubMedCrossRef
360.
361.
Zurück zum Zitat Girmenia C, Martino P (2003) New antifungal drugs and new clinical trials: interpreting results may be difficult. Curr Opin Oncol 15:283–288PubMedCrossRef Girmenia C, Martino P (2003) New antifungal drugs and new clinical trials: interpreting results may be difficult. Curr Opin Oncol 15:283–288PubMedCrossRef
362.
Zurück zum Zitat Herbrecht R, Denning DW, Paterson TF (2002) Voriconazole versus amphotericin B for primary therapy of invasive aspergillosis. N Engl J Med 347:408–415PubMedCrossRef Herbrecht R, Denning DW, Paterson TF (2002) Voriconazole versus amphotericin B for primary therapy of invasive aspergillosis. N Engl J Med 347:408–415PubMedCrossRef
363.
Zurück zum Zitat Javadi A, Ataei B, Koleini N, Saboori M (2010) Central nervous system aspergillosis in an immunocompetent patient. Neurosciences (Riyadh) 15:193–195 Javadi A, Ataei B, Koleini N, Saboori M (2010) Central nervous system aspergillosis in an immunocompetent patient. Neurosciences (Riyadh) 15:193–195
364.
Zurück zum Zitat Kowacs PA, Soares Silvado CE, Monteiro De Almeida S et al (2004) Infection of the CNS by Scedosporium apiospermum after near drowning. Report of a fatal case and analysis of its confounding factors. J Clin Pathol 57:205–207PubMedPubMedCentralCrossRef Kowacs PA, Soares Silvado CE, Monteiro De Almeida S et al (2004) Infection of the CNS by Scedosporium apiospermum after near drowning. Report of a fatal case and analysis of its confounding factors. J Clin Pathol 57:205–207PubMedPubMedCentralCrossRef
365.
Zurück zum Zitat Labadie EL, Hamilton RH (1986) Survival improvement in coccidioidal meningitis by high-dose intrathecal amphotericin B. Arch Intern Med 146:2013–2018PubMedCrossRef Labadie EL, Hamilton RH (1986) Survival improvement in coccidioidal meningitis by high-dose intrathecal amphotericin B. Arch Intern Med 146:2013–2018PubMedCrossRef
366.
Zurück zum Zitat Lazo A, Wilner HJ, Metes JJ (1981) Craniofacial mucormycosis: computed tomographic and angiographic findings in two cases. Radiology 139:623–626PubMedCrossRef Lazo A, Wilner HJ, Metes JJ (1981) Craniofacial mucormycosis: computed tomographic and angiographic findings in two cases. Radiology 139:623–626PubMedCrossRef
367.
Zurück zum Zitat Lowe JT, Hudson WR (1975) Rhinocerebral phycomycosis and internal carotid artery thrombosis. Arch Otolaryngol 101:100–103PubMedCrossRef Lowe JT, Hudson WR (1975) Rhinocerebral phycomycosis and internal carotid artery thrombosis. Arch Otolaryngol 101:100–103PubMedCrossRef
368.
Zurück zum Zitat Mathews M, Paré L, Hasso A (2007) Intraventricular cryptococcal cysts masquerading as racemose neurocysticercosis. Surg Neurol 67:647–649PubMedCrossRef Mathews M, Paré L, Hasso A (2007) Intraventricular cryptococcal cysts masquerading as racemose neurocysticercosis. Surg Neurol 67:647–649PubMedCrossRef
369.
Zurück zum Zitat Mazumder SA, Cleveland KO (2010) Cryptococcal meningitis after neurosurgery. Am J Med Sci 339:582–583PubMedCrossRef Mazumder SA, Cleveland KO (2010) Cryptococcal meningitis after neurosurgery. Am J Med Sci 339:582–583PubMedCrossRef
370.
Zurück zum Zitat Moen MD, Lyseng-Willliamson KA, Scott LJ (2009) Liposomal amphotericin B: a review of its use as empirical therapy in febrile neutropenia and in the treatment of invasive fungal infections. Drugs 69:361–392PubMedCrossRef Moen MD, Lyseng-Willliamson KA, Scott LJ (2009) Liposomal amphotericin B: a review of its use as empirical therapy in febrile neutropenia and in the treatment of invasive fungal infections. Drugs 69:361–392PubMedCrossRef
371.
Zurück zum Zitat Munoz P, Valerio M, Palomo J et al (2010) Infectious and non-infectious neurologic complications in heart transplant recipients. Medicine (Baltimore) 89:166–175CrossRef Munoz P, Valerio M, Palomo J et al (2010) Infectious and non-infectious neurologic complications in heart transplant recipients. Medicine (Baltimore) 89:166–175CrossRef
372.
Zurück zum Zitat Mylonakis E, Paliou M, Sax PE et al (2000) Central nervous system aspergillosis in patients with human iummuno-defficiency virus infection. Medicine 79:269–280PubMedCrossRef Mylonakis E, Paliou M, Sax PE et al (2000) Central nervous system aspergillosis in patients with human iummuno-defficiency virus infection. Medicine 79:269–280PubMedCrossRef
373.
Zurück zum Zitat Nevado J, De Alarcon A, Hernandez A (2005) Caspofungin: a new therapeutic option for fungal endocarditis. Clin Microbiol Infect 11:248–252PubMedCrossRef Nevado J, De Alarcon A, Hernandez A (2005) Caspofungin: a new therapeutic option for fungal endocarditis. Clin Microbiol Infect 11:248–252PubMedCrossRef
374.
Zurück zum Zitat Perea JR, Diaz De Rada BS, Quetglas EG et al (2004) Oral versus intravneous therapy in the treatment of systemic mycosis. Clin Microbiol Infect 1:96–106CrossRef Perea JR, Diaz De Rada BS, Quetglas EG et al (2004) Oral versus intravneous therapy in the treatment of systemic mycosis. Clin Microbiol Infect 1:96–106CrossRef
375.
Zurück zum Zitat Perlroth J, Choi B, Spellberg B (2007) Nosocomial fungal infections: epidemiology, diagnosis, and treatment. Med Mycol 45:321–346PubMedCrossRef Perlroth J, Choi B, Spellberg B (2007) Nosocomial fungal infections: epidemiology, diagnosis, and treatment. Med Mycol 45:321–346PubMedCrossRef
376.
Zurück zum Zitat Pfausler, Kampfl A, Berek K, Maier H, Aichner F, Schmutzhard E (1995) Syndrome of the Anterior Spinal Artery as the Primary Manifestation of Aspergillosis. Infection 23:240–242PubMedCrossRef Pfausler, Kampfl A, Berek K, Maier H, Aichner F, Schmutzhard E (1995) Syndrome of the Anterior Spinal Artery as the Primary Manifestation of Aspergillosis. Infection 23:240–242PubMedCrossRef
377.
Zurück zum Zitat Purkins L, Wood N, Ghahramani P et al (2003) Coadministration of voriconazole and phenytoin: pharmacokinetic interaction, safety, and toleration. Br J Clin Pharmacol 1:37–44CrossRef Purkins L, Wood N, Ghahramani P et al (2003) Coadministration of voriconazole and phenytoin: pharmacokinetic interaction, safety, and toleration. Br J Clin Pharmacol 1:37–44CrossRef
378.
Zurück zum Zitat Raman Sharma R (2010) Fungal infections of the nervous system: current perspective and controversies in management. Int J Surg 8:591–601PubMedCrossRef Raman Sharma R (2010) Fungal infections of the nervous system: current perspective and controversies in management. Int J Surg 8:591–601PubMedCrossRef
379.
Zurück zum Zitat Ramesha KN, Kate MP, Kesavadas C et al (2010) Fungal infections of the central nervous system in HIV-negative patients: experience from a tertiary referral center of South India. Ann Indian Acad Neurol 13:112–116PubMedPubMedCentralCrossRef Ramesha KN, Kate MP, Kesavadas C et al (2010) Fungal infections of the central nervous system in HIV-negative patients: experience from a tertiary referral center of South India. Ann Indian Acad Neurol 13:112–116PubMedPubMedCentralCrossRef
380.
Zurück zum Zitat Raparia K, Powell SZ, Cernoch P, Takei H (2010) Cerebral mycosis: 7-year retrospective series in a tertiary center. Neuropathology 30:218–223PubMedCrossRef Raparia K, Powell SZ, Cernoch P, Takei H (2010) Cerebral mycosis: 7-year retrospective series in a tertiary center. Neuropathology 30:218–223PubMedCrossRef
381.
Zurück zum Zitat Revankar SG, Sutton DA, Rinaldi MG (2004) Primary central nervous system phaeohyphomycocis: a review of 101 cases. Clin Infect Dis (38):206–216 Revankar SG, Sutton DA, Rinaldi MG (2004) Primary central nervous system phaeohyphomycocis: a review of 101 cases. Clin Infect Dis (38):206–216
382.
Zurück zum Zitat Rubio MC, de Ocariz IR, Gil J et al (2005) Potential fungicidal effect of voriconazole against Candida spp. Int J Antimicrob Agents 25:264–267PubMedCrossRef Rubio MC, de Ocariz IR, Gil J et al (2005) Potential fungicidal effect of voriconazole against Candida spp. Int J Antimicrob Agents 25:264–267PubMedCrossRef
383.
Zurück zum Zitat Ruchel R et al (1995) Cerebral Pseudallescheria mycosis after near-drowning. Mycoses 38:473–475PubMedCrossRef Ruchel R et al (1995) Cerebral Pseudallescheria mycosis after near-drowning. Mycoses 38:473–475PubMedCrossRef
384.
Zurück zum Zitat Sakhuja V, Sud K, Kalra OP et al (2001) Central nervous system complications in renal transplant recipients in a tropical environment. J Neurol Sci 183:89–93PubMedCrossRef Sakhuja V, Sud K, Kalra OP et al (2001) Central nervous system complications in renal transplant recipients in a tropical environment. J Neurol Sci 183:89–93PubMedCrossRef
385.
Zurück zum Zitat Sasaki T, Mineta M, Kobayashi K, Ando M, Obata M (2010) Zygomycotic invasion of the central nervous system. Jpn J Radiol 28:376–80PubMedCrossRef Sasaki T, Mineta M, Kobayashi K, Ando M, Obata M (2010) Zygomycotic invasion of the central nervous system. Jpn J Radiol 28:376–80PubMedCrossRef
386.
Zurück zum Zitat Schmutzhard E (2006) Fungal Infections. In: Noseworthy JH (Hrsg) Neurological Therapeutics-Principles and Practice. Informa Healthcare, Abingdon, Oxon, S 1085–1115 Schmutzhard E (2006) Fungal Infections. In: Noseworthy JH (Hrsg) Neurological Therapeutics-Principles and Practice. Informa Healthcare, Abingdon, Oxon, S 1085–1115
387.
388.
Zurück zum Zitat Senzolo M, Ferronato C, Burra P (2009) Neurologic complications after solid organ transplantation. Transpl Int 22:269–278PubMedCrossRef Senzolo M, Ferronato C, Burra P (2009) Neurologic complications after solid organ transplantation. Transpl Int 22:269–278PubMedCrossRef
389.
Zurück zum Zitat Shamin MS, Enam SA, Ali R, Anwar S (2010) Craniocerebral aspergillosis: a review of advances in diagnosis and management. J Pak Med Assoc 60:573–579 Shamin MS, Enam SA, Ali R, Anwar S (2010) Craniocerebral aspergillosis: a review of advances in diagnosis and management. J Pak Med Assoc 60:573–579
390.
Zurück zum Zitat Siegal JA, Cacayorinb ED, Nassif AS et al (2000) Cerebral mucormycosis: proton MR spectroscopy and MR imaging. Magn Reson Imaging 18:915–920PubMedCrossRef Siegal JA, Cacayorinb ED, Nassif AS et al (2000) Cerebral mucormycosis: proton MR spectroscopy and MR imaging. Magn Reson Imaging 18:915–920PubMedCrossRef
391.
Zurück zum Zitat Sun HY, Forrest G, Gupta KL et al (2010) Rhino-orbital-cerebral zygomycosis in solid organ transplant recipients. Transplantation 15:85–92CrossRef Sun HY, Forrest G, Gupta KL et al (2010) Rhino-orbital-cerebral zygomycosis in solid organ transplant recipients. Transplantation 15:85–92CrossRef
392.
Zurück zum Zitat Van Hal SJ, Clezy K (2005) Emergence of invasive cerebral aspergillosis in an HIV-positive patient on voriconazole therapy. HIV Med 6:45–46PubMedCrossRef Van Hal SJ, Clezy K (2005) Emergence of invasive cerebral aspergillosis in an HIV-positive patient on voriconazole therapy. HIV Med 6:45–46PubMedCrossRef
393.
Zurück zum Zitat Varanasi NL, Baskaran I, Alangaden GJ et al (2004) Novel effect of voriconazole on conidiation of Aspergillus species. Int J Antimicrob Agens 23:72–79CrossRef Varanasi NL, Baskaran I, Alangaden GJ et al (2004) Novel effect of voriconazole on conidiation of Aspergillus species. Int J Antimicrob Agens 23:72–79CrossRef
394.
Zurück zum Zitat Vos MJ, Debets-Ossenkopp YJ, Claessen FA et al (2000) Cerebellar and medullar histoplasmosis. Neurology 54:1441PubMedCrossRef Vos MJ, Debets-Ossenkopp YJ, Claessen FA et al (2000) Cerebellar and medullar histoplasmosis. Neurology 54:1441PubMedCrossRef
395.
Zurück zum Zitat Weng CT, Lee NY, Liu MF et al (2010) A retrospective study of catastrophic invasive fungal infections in patients with systemic lupus erythematosus from southern Taiwan. Lupus 19:1204–1209PubMedCrossRef Weng CT, Lee NY, Liu MF et al (2010) A retrospective study of catastrophic invasive fungal infections in patients with systemic lupus erythematosus from southern Taiwan. Lupus 19:1204–1209PubMedCrossRef
396.
Zurück zum Zitat Wingard JR, Leather H (2004) A new era of antifungal therapy. Biol Blood Marrow Transplant 10:73–90PubMedCrossRef Wingard JR, Leather H (2004) A new era of antifungal therapy. Biol Blood Marrow Transplant 10:73–90PubMedCrossRef
397.
Zurück zum Zitat Zivkovic (2007) Neuroimaging and neurologic complications after organ transplantation. J Neuroimaging 17:110–23PubMedCrossRef Zivkovic (2007) Neuroimaging and neurologic complications after organ transplantation. J Neuroimaging 17:110–23PubMedCrossRef
398.
Zurück zum Zitat Alhelm F et al (2006) Spondylitis/Spondylodiszitis. Radiologe 46:480–485CrossRef Alhelm F et al (2006) Spondylitis/Spondylodiszitis. Radiologe 46:480–485CrossRef
399.
Zurück zum Zitat Belzunegui J et al (1999) Vertebral osteomyelitis in northern Spain. Report of 62 cases. Clin Exp Rheumatol 177:447–452 Belzunegui J et al (1999) Vertebral osteomyelitis in northern Spain. Report of 62 cases. Clin Exp Rheumatol 177:447–452
400.
Zurück zum Zitat Beronius M, Bergman B, Andersson R (2001) Vertebral osteomyelitis in Göteborg, Sweden: a retrospective study of patients during 1990–95. Scand J Infect Dis 33:527–532PubMedCrossRef Beronius M, Bergman B, Andersson R (2001) Vertebral osteomyelitis in Göteborg, Sweden: a retrospective study of patients during 1990–95. Scand J Infect Dis 33:527–532PubMedCrossRef
401.
Zurück zum Zitat Chelsom J, Solberg CO (1998) Vertebral osteomyelitis at a Norwegian university hospital 1987–97: clinical features, laboratory findings and outcome. Scand J Infect Dis 30:147–151PubMedCrossRef Chelsom J, Solberg CO (1998) Vertebral osteomyelitis at a Norwegian university hospital 1987–97: clinical features, laboratory findings and outcome. Scand J Infect Dis 30:147–151PubMedCrossRef
402.
Zurück zum Zitat Cordonnier C et al (2003) Prospective study of patients presenting with acute partial transverse myelopathy. J Neurol 250:1447–1452PubMedCrossRef Cordonnier C et al (2003) Prospective study of patients presenting with acute partial transverse myelopathy. J Neurol 250:1447–1452PubMedCrossRef
403.
Zurück zum Zitat Debette S, de Sèze J, Pruvo J-P, Zephir H, Pasquier F, Leys D, Vermersch P (2009) Long-term outcome of acute and subacute myelopathies. J Neurol 256:980–988PubMedCrossRef Debette S, de Sèze J, Pruvo J-P, Zephir H, Pasquier F, Leys D, Vermersch P (2009) Long-term outcome of acute and subacute myelopathies. J Neurol 256:980–988PubMedCrossRef
404.
Zurück zum Zitat De Seze J et al (2001) Acute Myelopathies. Clinical. Laboratory and outcome profiles in 79 patients. Brain 124:1509–1521PubMedCrossRef De Seze J et al (2001) Acute Myelopathies. Clinical. Laboratory and outcome profiles in 79 patients. Brain 124:1509–1521PubMedCrossRef
405.
Zurück zum Zitat Duncan S, Halfpenny C, Galea I (2014) CNS inflammation other than multiple sclerosis: How likely is diagnosis? Neurology 82:1187–1189CrossRef Duncan S, Halfpenny C, Galea I (2014) CNS inflammation other than multiple sclerosis: How likely is diagnosis? Neurology 82:1187–1189CrossRef
406.
Zurück zum Zitat Erickson BJ, Weinshenker BG (2010) Compressive myelopathy mimicking transverse myelitis. Neurologist 16:120–122PubMedCrossRef Erickson BJ, Weinshenker BG (2010) Compressive myelopathy mimicking transverse myelitis. Neurologist 16:120–122PubMedCrossRef
407.
Zurück zum Zitat Frohmann EM, Wingerchuk DM (2010) Clinical Practice. Transverse Myelitis. N Engl J Med 363:564–572CrossRef Frohmann EM, Wingerchuk DM (2010) Clinical Practice. Transverse Myelitis. N Engl J Med 363:564–572CrossRef
408.
Zurück zum Zitat Grabowski A (2013) Manual Neurologische Akut- und Intensivmedizin. Schattauer, Stuttgart Grabowski A (2013) Manual Neurologische Akut- und Intensivmedizin. Schattauer, Stuttgart
409.
Zurück zum Zitat Greenberg BM et al (2007) Idiopathic transverse myelitis. Corticosteroids, plasma exchange, or cyclophosphamid. Neurology 68:1614–1617PubMedCrossRef Greenberg BM et al (2007) Idiopathic transverse myelitis. Corticosteroids, plasma exchange, or cyclophosphamid. Neurology 68:1614–1617PubMedCrossRef
412.
Zurück zum Zitat Irani DN, Kerr DA (2000) 14-3-3 protein in the cerebrospinal fluid of patients with acute transverse myelitis. Lancet 355(9207):901PubMedCrossRef Irani DN, Kerr DA (2000) 14-3-3 protein in the cerebrospinal fluid of patients with acute transverse myelitis. Lancet 355(9207):901PubMedCrossRef
413.
Zurück zum Zitat Jacob A, Weinshenker BG (2008) An Approach to the Diagnosis of Acute Tranverse Myelitis. Semin Neurol 28:105–120PubMedCrossRef Jacob A, Weinshenker BG (2008) An Approach to the Diagnosis of Acute Tranverse Myelitis. Semin Neurol 28:105–120PubMedCrossRef
414.
Zurück zum Zitat Kalita J, Misra UK, Mandal SK (1998) Prognostic predictors of acute transverse myelitis. Acta Neurol Scand 98:60–63PubMedCrossRef Kalita J, Misra UK, Mandal SK (1998) Prognostic predictors of acute transverse myelitis. Acta Neurol Scand 98:60–63PubMedCrossRef
415.
Zurück zum Zitat Kalita J, Misra UK (2000) Neurophysiological studies in acute transverse myelitis. J Neurol 247:943–948PubMedCrossRef Kalita J, Misra UK (2000) Neurophysiological studies in acute transverse myelitis. J Neurol 247:943–948PubMedCrossRef
416.
Zurück zum Zitat Kalita J, Misra UK (2001) Is methyl prednisolone useful in acute transverse myelitis? Spinal Cord 39:471–476PubMedCrossRef Kalita J, Misra UK (2001) Is methyl prednisolone useful in acute transverse myelitis? Spinal Cord 39:471–476PubMedCrossRef
417.
Zurück zum Zitat Karussis D, Petrou P (2014) The spectrum of post-vaccination inflammatory CNS demyelinating syndromes. Autoimm Rev 13:215–224CrossRef Karussis D, Petrou P (2014) The spectrum of post-vaccination inflammatory CNS demyelinating syndromes. Autoimm Rev 13:215–224CrossRef
418.
Zurück zum Zitat Krishnan C et al (2004) Transverse Myelitis: pathogenesis, diagnosis and treatment. Front Biosci 9:1483–1499PubMedCrossRef Krishnan C et al (2004) Transverse Myelitis: pathogenesis, diagnosis and treatment. Front Biosci 9:1483–1499PubMedCrossRef
419.
Zurück zum Zitat Lewis M, Howdle (2003) The neurology of liver failure. Q J Med 96:623–633CrossRef Lewis M, Howdle (2003) The neurology of liver failure. Q J Med 96:623–633CrossRef
420.
Zurück zum Zitat Mealy M, Wingerchuck D, Palace J, Greenberg B, Levy B (2014) Comparison of Relapse and Treatment Failure Rates Among Patients With Neuromyelitis Optica. Multicenter Study of Treatment Efficacy. JAMA Neurology 71:324–330PubMedCrossRef Mealy M, Wingerchuck D, Palace J, Greenberg B, Levy B (2014) Comparison of Relapse and Treatment Failure Rates Among Patients With Neuromyelitis Optica. Multicenter Study of Treatment Efficacy. JAMA Neurology 71:324–330PubMedCrossRef
421.
Zurück zum Zitat Meyding-Lamadé U et al (2005) Akute spinale Entzündungen. Intensivmed 42:337–344CrossRef Meyding-Lamadé U et al (2005) Akute spinale Entzündungen. Intensivmed 42:337–344CrossRef
423.
Zurück zum Zitat Schellinger PD, Schmutzhard E, Fiebach JB, Pfausler B, Maier H, Schwab S (2000) Poliomyelitic-like illness in central european encephalitis. Neurology 55:299–302PubMedCrossRef Schellinger PD, Schmutzhard E, Fiebach JB, Pfausler B, Maier H, Schwab S (2000) Poliomyelitic-like illness in central european encephalitis. Neurology 55:299–302PubMedCrossRef
424.
Zurück zum Zitat Schlossbauer T, Panteleon A, Becker-Gaab C (2006) Entzündliche Wirbelsäulenerkrankungen als Ursache für Rückenschmerzen. Radiologe 46:468–479PubMedCrossRef Schlossbauer T, Panteleon A, Becker-Gaab C (2006) Entzündliche Wirbelsäulenerkrankungen als Ursache für Rückenschmerzen. Radiologe 46:468–479PubMedCrossRef
425.
Zurück zum Zitat Schmalstieg W, Weinshenker BG (2010) Approach to acute or subacute myelopathy. Neurology Clinical Practice 75(1):2–S8 Schmalstieg W, Weinshenker BG (2010) Approach to acute or subacute myelopathy. Neurology Clinical Practice 75(1):2–S8
426.
Zurück zum Zitat Sellner J et al (2010) EFNS Guidelines on diagnosis and management of neuromyelitis optica. Eur J Neurol 17:1019–1032PubMedCrossRef Sellner J et al (2010) EFNS Guidelines on diagnosis and management of neuromyelitis optica. Eur J Neurol 17:1019–1032PubMedCrossRef
427.
Zurück zum Zitat Transverse Myelitis Consortium Working Group Neurology (2002) Proposed diagnostic citeria and nosology of acute tranverse myelitis. Neurology 59:499–505CrossRef Transverse Myelitis Consortium Working Group Neurology (2002) Proposed diagnostic citeria and nosology of acute tranverse myelitis. Neurology 59:499–505CrossRef
428.
Zurück zum Zitat West T, Hess C, Cree B (2012) Acute transverse Myelitis: Demyelinating, Inflammatory, and infectious Myelopathies. Semin Neurol 32:97–113PubMedCrossRef West T, Hess C, Cree B (2012) Acute transverse Myelitis: Demyelinating, Inflammatory, and infectious Myelopathies. Semin Neurol 32:97–113PubMedCrossRef
429.
430.
Metadaten
Titel
Infektionen
verfasst von
Matthias Klein, PD Dr.
Hans-Walter Pfister, Prof. Dr.
Erich Schmutzhard, Prof. Dr.
Uta Meyding-Lamadé, Prof. Dr.
Corinna Schranz, Dr.
Gabriele Arendt, Prof. Dr.
Raimund Helbok, PD Dr.
Bettina Pfausler, PD Dr.
André Grabowski, Dr.
Bodo Kress, Prof. Dr.
Ronny Beer, PD Dr.
Copyright-Jahr
2015
Verlag
Springer Berlin Heidelberg
DOI
https://doi.org/10.1007/978-3-662-46500-4_32

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