Skip to main content
Erschienen in: High Blood Pressure & Cardiovascular Prevention 1/2024

29.01.2024 | Original article

Child Marriage and Cardiovascular Risk: An Application of the Non-laboratory Framingham Risk Score

verfasst von: Biplab Kumar Datta, Benjamin E. Ansa, Ashley Saucier, Ajay Pandey, Mohammad Rifat Haider, Racquel Puranda, Malika Adams, Janis Coffin

Erschienen in: High Blood Pressure & Cardiovascular Prevention | Ausgabe 1/2024

Einloggen, um Zugang zu erhalten

Abstract

Introduction

Child marriage, defined as marriage before the age of 18 years, is a precocious transition from adolescence to adulthood, which may take a long-term toll on health.

Aim

This study aims to assess whether child marriage was associated with added risk of adverse cardiovascular outcomes in a nationally representative sample of Indian adults.

Methods

Applying the non-laboratory-based Framingham algorithm to data on 336,953 women aged 30–49 years and 49,617 men aged 30–54 years, we estimated individual’s predicted heart age (PHA). Comparing the PHA with chronological age (CA), we categorized individuals in four groups: (i) low PHA: PHA < CA, (ii) equal PHA: PHA = CA (reference category), (iii) high PHA: PHA > CA by at most 4 years, and (iv) very high PHA: PHA > CA by 5 + years. We estimated multivariable multinomial logistic regressions to obtain relative risks of respective categories for the child marriage indicator.

Results

We found that women who were married in childhood had 1.06 (95% CI 1.01–1.10) and 1.22 (95% CI 1.16–1.27) times higher adjusted risks of having high and very high PHA, respectively, compared to women who were married as adults. For men, no differential risks were found between those who were married as children and as adults. These results were generally robust across various socioeconomic sub-groups.

Conclusions

These findings add to the relatively new and evolving strand of literature that examines the role of child marriage on later life chronic health outcomes and provide important insights for public health policies aimed at improving women’s health and wellbeing.
Literatur
3.
Zurück zum Zitat Global Cardiovascular Risk Consortium. Global effect of modifiable risk factors on cardiovascular disease and mortality. N Engl J Med. 2023;389(14):1273–85.CrossRef Global Cardiovascular Risk Consortium. Global effect of modifiable risk factors on cardiovascular disease and mortality. N Engl J Med. 2023;389(14):1273–85.CrossRef
4.
Zurück zum Zitat Gaziano TA, Abrahams-Gessel S, Alam S, Alam D, Ali M, Bloomfield G, Carrillo-Larco RM, Prabhakaran D, Gutierrez L, Irazola V, Levitt NS. Comparison of nonblood-based and blood-based total CV risk scores in global populations. Glob Heart. 2016;11(1):37–46.CrossRefPubMed Gaziano TA, Abrahams-Gessel S, Alam S, Alam D, Ali M, Bloomfield G, Carrillo-Larco RM, Prabhakaran D, Gutierrez L, Irazola V, Levitt NS. Comparison of nonblood-based and blood-based total CV risk scores in global populations. Glob Heart. 2016;11(1):37–46.CrossRefPubMed
5.
Zurück zum Zitat Kariuki JK, Stuart-Shor EM, Leveille SG, Hayman LL. Evaluation of the performance of existing non-laboratory based cardiovascular risk assessment algorithms. BMC Cardiovasc Disord. 2013;13:1–3.CrossRef Kariuki JK, Stuart-Shor EM, Leveille SG, Hayman LL. Evaluation of the performance of existing non-laboratory based cardiovascular risk assessment algorithms. BMC Cardiovasc Disord. 2013;13:1–3.CrossRef
6.
Zurück zum Zitat Appiah D, Capistrant BD. Cardiovascular Disease risk assessment in the United States and low-and middle-income countries using predicted heart/vascular age. Sci Rep. 2017;7(1):16673.ADSCrossRefPubMedPubMedCentral Appiah D, Capistrant BD. Cardiovascular Disease risk assessment in the United States and low-and middle-income countries using predicted heart/vascular age. Sci Rep. 2017;7(1):16673.ADSCrossRefPubMedPubMedCentral
7.
Zurück zum Zitat Saidi O, Malouche D, O’Flaherty M, Mansour NB, Skhiri HA, Romdhane HB, Bezdah L. Assessment of cardiovascular risk in Tunisia: applying the Framingham risk score to national survey data. BMJ Open. 2016;6(11): e009195.CrossRefPubMedPubMedCentral Saidi O, Malouche D, O’Flaherty M, Mansour NB, Skhiri HA, Romdhane HB, Bezdah L. Assessment of cardiovascular risk in Tunisia: applying the Framingham risk score to national survey data. BMJ Open. 2016;6(11): e009195.CrossRefPubMedPubMedCentral
8.
Zurück zum Zitat Tabaei BP, Chamany S, Perlman S, Thorpe L, Bartley K, Wu WY. Heart age, Cardiovascular Disease risk, and disparities by sex and race/ethnicity among New York City adults. Public Health Rep. 2019;134(4):404–16.CrossRefPubMedPubMedCentral Tabaei BP, Chamany S, Perlman S, Thorpe L, Bartley K, Wu WY. Heart age, Cardiovascular Disease risk, and disparities by sex and race/ethnicity among New York City adults. Public Health Rep. 2019;134(4):404–16.CrossRefPubMedPubMedCentral
9.
Zurück zum Zitat Zmora R, Schreiner PJ, Appiah D, Lloyd-Jones DM, Rana JS, Lewis CE. Racial and sex differences in biological and chronological heart age in the coronary artery risk development in young adults study. Ann Epidemiol. 2019;33:24–9.CrossRefPubMedPubMedCentral Zmora R, Schreiner PJ, Appiah D, Lloyd-Jones DM, Rana JS, Lewis CE. Racial and sex differences in biological and chronological heart age in the coronary artery risk development in young adults study. Ann Epidemiol. 2019;33:24–9.CrossRefPubMedPubMedCentral
10.
Zurück zum Zitat Yang Q, Zhong Y, Ritchey M, Loustalot F, Hong Y, Merritt R, Bowman BA. Predicted 10-year risk of developing cardiovascular disease at the state level in the US. Am J Prev Med. 2015;48(1):58–69.CrossRefPubMed Yang Q, Zhong Y, Ritchey M, Loustalot F, Hong Y, Merritt R, Bowman BA. Predicted 10-year risk of developing cardiovascular disease at the state level in the US. Am J Prev Med. 2015;48(1):58–69.CrossRefPubMed
11.
Zurück zum Zitat Guzman-Vilca WC, Quispe-Villegas GA, Carrillo-Larco RM. Predicted heart age profile across 41 countries: a cross-sectional study of nationally representative surveys in six world regions. Eclinicalmedicine. 2022;52: 101688.CrossRefPubMedPubMedCentral Guzman-Vilca WC, Quispe-Villegas GA, Carrillo-Larco RM. Predicted heart age profile across 41 countries: a cross-sectional study of nationally representative surveys in six world regions. Eclinicalmedicine. 2022;52: 101688.CrossRefPubMedPubMedCentral
12.
Zurück zum Zitat Wickrama KA, Lee TK, O’Neal CW. Stressful life experiences in adolescence and cardiometabolic risk factors in young adulthood. J Adolesc Health. 2015;56(4):456–63.CrossRefPubMed Wickrama KA, Lee TK, O’Neal CW. Stressful life experiences in adolescence and cardiometabolic risk factors in young adulthood. J Adolesc Health. 2015;56(4):456–63.CrossRefPubMed
13.
Zurück zum Zitat Fan S, Koski A. The health consequences of child marriage: a systematic review of the evidence. BMC Public Health. 2022;22(1):1–7.CrossRef Fan S, Koski A. The health consequences of child marriage: a systematic review of the evidence. BMC Public Health. 2022;22(1):1–7.CrossRef
14.
Zurück zum Zitat Misunas C, Gastón CM, Cappa C. Child marriage among boys in high-prevalence countries: an analysis of sexual and reproductive health outcomes. BMC Int Health Hum Rights. 2019;19(1):1–6.CrossRef Misunas C, Gastón CM, Cappa C. Child marriage among boys in high-prevalence countries: an analysis of sexual and reproductive health outcomes. BMC Int Health Hum Rights. 2019;19(1):1–6.CrossRef
15.
Zurück zum Zitat Datta BK, Haider MR, Tiwari A, Jahan M. The risk of Hypertension among child brides and adolescent mothers at age 20 s, 30 s, and 40 s: evidence from India. J Hum Hypertens. 2022;23:1–8. Datta BK, Haider MR, Tiwari A, Jahan M. The risk of Hypertension among child brides and adolescent mothers at age 20 s, 30 s, and 40 s: evidence from India. J Hum Hypertens. 2022;23:1–8.
16.
Zurück zum Zitat Datta B, Tiwari A. Early marriage in adolescence and risk of High Blood Pressure and high blood glucose in adulthood: evidence from India. Women. 2022;2(3):189–203.CrossRef Datta B, Tiwari A. Early marriage in adolescence and risk of High Blood Pressure and high blood glucose in adulthood: evidence from India. Women. 2022;2(3):189–203.CrossRef
17.
Zurück zum Zitat Datta B, Tiwari A, Glenn L. Stolen childhood taking a toll at young adulthood: the higher risk of High Blood Pressure and high blood glucose comorbidity among child brides. PLOS Global Public Health. 2022;2(6): e0000638.CrossRefPubMedPubMedCentral Datta B, Tiwari A, Glenn L. Stolen childhood taking a toll at young adulthood: the higher risk of High Blood Pressure and high blood glucose comorbidity among child brides. PLOS Global Public Health. 2022;2(6): e0000638.CrossRefPubMedPubMedCentral
18.
Zurück zum Zitat Vikram K, Visaria A, Ganguly D. Child marriage as a risk factor for non-communicable Diseases among women in India. Int J Epidemiol. 2023;9: dyad051. Vikram K, Visaria A, Ganguly D. Child marriage as a risk factor for non-communicable Diseases among women in India. Int J Epidemiol. 2023;9: dyad051.
19.
Zurück zum Zitat Datta BK, Haider MR. The double burden of overweight or obesity and anemia among women married as children in India: a case of the Simpson’s paradox. Obes Res Clin Pract. 2022. Datta BK, Haider MR. The double burden of overweight or obesity and anemia among women married as children in India: a case of the Simpson’s paradox. Obes Res Clin Pract. 2022.
20.
Zurück zum Zitat Datta B, Tiwari A, Attari S. Child marriage and later-life risk of obesity in women: a cohort analysis using nationally Representative repeated Cross-sectional Data from Tajikistan. Women. 2023;3(1):53–70.CrossRef Datta B, Tiwari A, Attari S. Child marriage and later-life risk of obesity in women: a cohort analysis using nationally Representative repeated Cross-sectional Data from Tajikistan. Women. 2023;3(1):53–70.CrossRef
21.
Zurück zum Zitat Datta BK, Tiwari A, Fazlul I. Child marriage and risky health behaviors: an analysis of Tobacco use among early adult and early middle-aged women in India. BMC Womens Health. 2022;22(1):1–4.CrossRef Datta BK, Tiwari A, Fazlul I. Child marriage and risky health behaviors: an analysis of Tobacco use among early adult and early middle-aged women in India. BMC Womens Health. 2022;22(1):1–4.CrossRef
25.
Zurück zum Zitat D’Agostino Sr RB, Vasan RS, Pencina MJ, Wolf PA, Cobain M, Massaro JM, Kannel WB. General cardiovascular risk profile for use in primary care: the Framingham heart Study. Circulation. 2008;117(6):743–53.CrossRefPubMed D’Agostino Sr RB, Vasan RS, Pencina MJ, Wolf PA, Cobain M, Massaro JM, Kannel WB. General cardiovascular risk profile for use in primary care: the Framingham heart Study. Circulation. 2008;117(6):743–53.CrossRefPubMed
26.
Zurück zum Zitat Scott LC, Yang Q, Dowling NF, Richardson LC. Predicted heart age among cancer survivors—United States, 2013–2017. Morb Mortal Wkly Rep. 2021;70(1): 1.CrossRef Scott LC, Yang Q, Dowling NF, Richardson LC. Predicted heart age among cancer survivors—United States, 2013–2017. Morb Mortal Wkly Rep. 2021;70(1): 1.CrossRef
27.
Zurück zum Zitat Gupta R, Kaul V, Agrawal A, Guptha S, Gupta VP. Cardiovascular risk according to educational status in India. Prev Med. 2010;51(5):408–11.CrossRefPubMed Gupta R, Kaul V, Agrawal A, Guptha S, Gupta VP. Cardiovascular risk according to educational status in India. Prev Med. 2010;51(5):408–11.CrossRefPubMed
28.
Zurück zum Zitat Geldsetzer P, Manne-Goehler J, Theilmann M, Davies JI, Awasthi A, Danaei G, Gaziano TA, Vollmer S, Jaacks LM, Baernighausen T, Atun R. Geographic and sociodemographic variation of cardiovascular disease risk in India: a cross-sectional study of 797,540 adults. PLoS Med. 2018;15(6): e1002581.CrossRefPubMedPubMedCentral Geldsetzer P, Manne-Goehler J, Theilmann M, Davies JI, Awasthi A, Danaei G, Gaziano TA, Vollmer S, Jaacks LM, Baernighausen T, Atun R. Geographic and sociodemographic variation of cardiovascular disease risk in India: a cross-sectional study of 797,540 adults. PLoS Med. 2018;15(6): e1002581.CrossRefPubMedPubMedCentral
29.
Zurück zum Zitat Paul P. Effects of education and poverty on the prevalence of girl child marriage in India: a district–level analysis. Child Youth Serv Rev. 2019;100:16–21.CrossRef Paul P. Effects of education and poverty on the prevalence of girl child marriage in India: a district–level analysis. Child Youth Serv Rev. 2019;100:16–21.CrossRef
30.
Zurück zum Zitat Das J, Holla A, Das V, Mohanan M, Tabak D, Chan B. In urban and rural India, a standardized patient study showed low levels of provider training and huge quality gaps. Health Aff. 2012;31(12):2774–84.CrossRef Das J, Holla A, Das V, Mohanan M, Tabak D, Chan B. In urban and rural India, a standardized patient study showed low levels of provider training and huge quality gaps. Health Aff. 2012;31(12):2774–84.CrossRef
31.
Zurück zum Zitat Schultz WM, Kelli HM, Lisko JC, Varghese T, Shen J, Sandesara P, Quyyumi AA, Taylor HA, Gulati M, Harold JG, Mieres JH. Socioeconomic status and cardiovascular outcomes: challenges and interventions. Circulation. 2018;137(20):2166–78.CrossRefPubMedPubMedCentral Schultz WM, Kelli HM, Lisko JC, Varghese T, Shen J, Sandesara P, Quyyumi AA, Taylor HA, Gulati M, Harold JG, Mieres JH. Socioeconomic status and cardiovascular outcomes: challenges and interventions. Circulation. 2018;137(20):2166–78.CrossRefPubMedPubMedCentral
32.
Zurück zum Zitat Kanejima Y, Shimogai T, Kitamura M, Ishihara K, Izawa KP. Impact of health literacy in patients with cardiovascular diseases: a systematic review and meta-analysis. Patient Educ Couns. 2022;105(7):1793–800.CrossRefPubMed Kanejima Y, Shimogai T, Kitamura M, Ishihara K, Izawa KP. Impact of health literacy in patients with cardiovascular diseases: a systematic review and meta-analysis. Patient Educ Couns. 2022;105(7):1793–800.CrossRefPubMed
33.
34.
Zurück zum Zitat Psaki SR, Melnikas AJ, Haque E, Saul G, Misunas C, Patel SK, Ngo T, Amin S. What are the drivers of child marriage? A conceptual framework to guide policies and programs. J Adolesc Health. 2021;69(6):13–22.CrossRef Psaki SR, Melnikas AJ, Haque E, Saul G, Misunas C, Patel SK, Ngo T, Amin S. What are the drivers of child marriage? A conceptual framework to guide policies and programs. J Adolesc Health. 2021;69(6):13–22.CrossRef
35.
Zurück zum Zitat Santosa A, Rosengren A, Ramasundarahettige C, Rangarajan S, Gulec S, Chifamba J, Lear SA, Poirier P, Yeates KE, Yusuf R, Orlandini A. Psychosocial risk factors and cardiovascular disease and death in a population-based cohort from 21 low-, middle-, and high-income countries. JAMA Netw open. 2021;4(12):e2138920.CrossRefPubMedPubMedCentral Santosa A, Rosengren A, Ramasundarahettige C, Rangarajan S, Gulec S, Chifamba J, Lear SA, Poirier P, Yeates KE, Yusuf R, Orlandini A. Psychosocial risk factors and cardiovascular disease and death in a population-based cohort from 21 low-, middle-, and high-income countries. JAMA Netw open. 2021;4(12):e2138920.CrossRefPubMedPubMedCentral
36.
Zurück zum Zitat Molitoris J, Kantorová V, Ezdi S, Gonnella G. Early childbearing and child marriage: an update. Studies in Family Planning. 2023;54(3):503–21.CrossRefPubMed Molitoris J, Kantorová V, Ezdi S, Gonnella G. Early childbearing and child marriage: an update. Studies in Family Planning. 2023;54(3):503–21.CrossRefPubMed
37.
Zurück zum Zitat Rosendaal NT, Pirkle CM. Age at first birth and risk of later-life cardiovascular disease: a systematic review of the literature, its limitation, and recommendations for future research. BMC Public Health. 2017;17:1–5.CrossRef Rosendaal NT, Pirkle CM. Age at first birth and risk of later-life cardiovascular disease: a systematic review of the literature, its limitation, and recommendations for future research. BMC Public Health. 2017;17:1–5.CrossRef
Metadaten
Titel
Child Marriage and Cardiovascular Risk: An Application of the Non-laboratory Framingham Risk Score
verfasst von
Biplab Kumar Datta
Benjamin E. Ansa
Ashley Saucier
Ajay Pandey
Mohammad Rifat Haider
Racquel Puranda
Malika Adams
Janis Coffin
Publikationsdatum
29.01.2024
Verlag
Springer International Publishing
Erschienen in
High Blood Pressure & Cardiovascular Prevention / Ausgabe 1/2024
Print ISSN: 1120-9879
Elektronische ISSN: 1179-1985
DOI
https://doi.org/10.1007/s40292-023-00620-2

Weitere Artikel der Ausgabe 1/2024

High Blood Pressure & Cardiovascular Prevention 1/2024 Zur Ausgabe

Nach Herzinfarkt mit Typ-1-Diabetes schlechtere Karten als mit Typ 2?

29.05.2024 Herzinfarkt Nachrichten

Bei Menschen mit Typ-2-Diabetes sind die Chancen, einen Myokardinfarkt zu überleben, in den letzten 15 Jahren deutlich gestiegen – nicht jedoch bei Betroffenen mit Typ 1.

Erhöhtes Risiko fürs Herz unter Checkpointhemmer-Therapie

28.05.2024 Nebenwirkungen der Krebstherapie Nachrichten

Kardiotoxische Nebenwirkungen einer Therapie mit Immuncheckpointhemmern mögen selten sein – wenn sie aber auftreten, wird es für Patienten oft lebensgefährlich. Voruntersuchung und Monitoring sind daher obligat.

GLP-1-Agonisten können Fortschreiten diabetischer Retinopathie begünstigen

24.05.2024 Diabetische Retinopathie Nachrichten

Möglicherweise hängt es von der Art der Diabetesmedikamente ab, wie hoch das Risiko der Betroffenen ist, dass sich sehkraftgefährdende Komplikationen verschlimmern.

TAVI versus Klappenchirurgie: Neue Vergleichsstudie sorgt für Erstaunen

21.05.2024 TAVI Nachrichten

Bei schwerer Aortenstenose und obstruktiver KHK empfehlen die Leitlinien derzeit eine chirurgische Kombi-Behandlung aus Klappenersatz plus Bypass-OP. Diese Empfehlung wird allerdings jetzt durch eine aktuelle Studie infrage gestellt – mit überraschender Deutlichkeit.

Update Kardiologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.