Erschienen in:
01.09.2013 | e-Herz: Case study
Cardiac syncope due to pain
Report of a case responsive to duloxetine treatment
verfasst von:
C. Kaplan, Dr. S.A. Kocaman, M.E. Durakoğlugil, E. Kaya, M.G. Şenol
Erschienen in:
Herz
|
Ausgabe 6/2013
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Abstract
Neurocardiogenic syncope comprises situations triggered by neurological reflexes resulting in abnormal responses of the neurocardiovascular system that cause loss of consciousness. A vast number of clinical conditions may cause this disorder including pain, defecation, micturition, swallowing, cough, sudden fear or excitement, exercise, and long-time standing. Treatment options for syncope prevention are not satisfactory. Several agents were used for pharmacological treatment without success. Selective inhibitors of neuronal norepinephrine transporter (NET) like duloxetine may play a role in neurally mediated syncope by increasing synaptic norepinephrine levels. Therefore, we report the effect of duloxetine in a patient with pain-induced syncope resistant to standard regimens.