Fig. 1
A Non-regularized partial-correlation network of anxiety and depression symptoms and OTCA usage. Blue edges represent positive and red edges represent negative partial correlations. The OTCA node is placed in the centre of a circle consisting of the remaining variables. To facilitate interpretation, all other edges than those connected to OTCA have been omitted from the graphical presentation. The thickness and brightness of an edge indicate association strength.
Legends: OTCA: Paracetamol, ibuprofen or similar, AD1: Felt that everything is a struggle (edge weight: 0.07), AD2: Had sleep problems (0.1), AD3: Felt unhappy, sad or depressed (0.02), AD4: Felt hopeless about the future (− 0.01), AD5: Felt stiff or tense (0.09), AD6: Worried too much about things (0.02), AD7: Felt lonely (− 0.01), AD8: Suddenlty felt scared for no reason (0.05), AD9: Felt constant fear or anxiety (0.01), AD10: Been nervous or felt uneasy (0.0). B Non-regularized partial-correlation network with pain symptoms as covariates. Blue edges represent positive and red edges represent negative partial correlations. The OTCA node is placed in the centre of a circle consisting of the remaining variables. To facilitate interpretation, all other edges than those connected to OTCA have been omitted from the graphical presentation. The thickness and brightness of an edge indicate association strength.
Legends: OTCA: Paracetamol, ibuprofen or similar, AD1: Felt that everything is a struggle (edge weight: 0.03), AD2: Had sleep problems (0.05), AD3: Felt unhappy, sad or depressed (0.01), AD4: Felt hopeless about the future (0.0), AD5: Felt stiff or tense (0.03), AD6: Worried too much about things (0.0), AD7: Felt lonely (− 0.01), AD8: Suddenly felt scared for no reason (0.02), AD9: Felt constant fear or anxiety (0.01), AD10: Been nervous or felt uneasy (− 0.01), P1: Headache (0.3), P2: Neck and shoulder pain (0.01), P3: Joint and muscle pain (0.06), P4: Abdominal pain (0.09)