Erschienen in:
16.04.2024 | REVIEW
Ablation of Kidney Tumors in Patients with Substantial Kidney Impairment: Current Status
verfasst von:
Toshihiro Iguchi, Yusuke Matsui, Koji Tomita, Mayu Uka, Noriyuki Umakoshi, Takahiro Kawabata, Hideo Gobara, Motoo Araki, Takao Hiraki
Erschienen in:
Current Oncology Reports
|
Ausgabe 5/2024
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Abstract
Purpose of review
To review the current status of kidney tumor ablation in patients with substantial kidney impairment.
Recent findings
Few reports of kidney tumor ablation in such patients have recently been published. The reported prevalence of patients with stage 4 or 5 chronic kidney disease (CKD) among patients undergoing ablation is 2.0%–10%. In patients with stage 4 or 5 CKD, local tumor control rates were 88%–100%. The effect of ablation on CKD stage is unclear, and the observed deteriorations in kidney function are consistent with both the effect of cryoablation and the natural course of advanced CKD.
Summary
According to guidelines, active surveillance may be selected. The goals of treatment are complete tumor removal and maintenance of kidney function, both of which can be met by ablation. Given the limited treatment options, ablation may play a pivotal role in the management of patients with advanced CKD.