Periprosthetic joint infections (PJIs) remain a very challenging complication of total hip and total knee arthroplasties (THA and TKA, respectively). PJI is one of the three most common reasons for revision of THA and TKA, placing a substantial …
verfasst von:
Viktor Janz, Anastasia Rakow, Leonie Schröder, André Hofer, Sergej Wiebe, Janosch Schoon, Stefan Weiss, Barbara M. Bröker, Georgi I. Wassilew, Dina Raafat
The coronavirus disease 2019 (COVID-19) pandemic has shown the global impact of emerging infectious diseases, including the burden on healthcare systems, socio-psychological implications, and economic damage [ 1 , 2 ]. The global response to public …
verfasst von:
Julia A. Nacov, Jannik Stemler, Jon Salmanton-García, Louise M. Cremer, Markus Zeitlinger, Patrick W. G. Mallon, Zoi Dorothea Pana, Heinz-Josef Schmitt, Oliver A. Cornely, On behalf of the VACCELERATE Consortium
The pathogen Aspergillus fumigatus has been included as critical in the WHO fungal priority pathogen list. This inclusion stems from its prevalence in human infections and the diverse challenges it poses in contemporary management. Of particular …
verfasst von:
Patricia Monzo-Gallo, Ana Alastruey-Izquierdo, Mariana Chumbita, Tommaso Francesco Aiello, Antonio Gallardo-Pizarro, Olivier Peyrony, Christian Teijon-Lumbreras, Laura Alcazar-Fuoli, Mateu Espasa, Alex Soriano, Francesc Marco, Carolina Garcia-Vidal
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of the highly contagious respiratory disease Corona Virus Disease 2019 (COVID-19) that may lead to various neurological and psychological disorders that can be …
verfasst von:
Mona Dehhaghi, Mostafa Heydari, Hamed Kazemi Shariat Panahi, Sharon R. Lewin, Benjamin Heng, Bruce J. Brew, Gilles J. Guillemin
Award of the 2023 creative competition. In the absence of clinical symptoms of a urinary tract infection, antibiotic therapy is not necessary if bacteriuria is detected (asymptomatic bacteriuria), with a few exceptions.
Very preterm infants (born before 32 weeks of gestation) show greater risk of infections in early life, with risks increasing with the degree of immaturity, particularly in those born small for gestational age (SGA) [ 1 , 2 ]. These vulnerable …
verfasst von:
Ole Bæk, Tik Muk, Lise Aunsholt, Gitte Zachariasen, Per Torp Sangild, Duc Ninh Nguyen
Patients with complex infectious diseases (especially when undergoing anti-infective prophylaxis) pose a challenge even with modern diagnostic laboratory methods, especially when direct pathogen detection is required within a short period of time.
verfasst von:
Sven Kalbitz, Jörg Ermisch, Nils Kellner, Olaf Nickel, Stephan Borte, Kathrin Marx, Christoph Lübbert
Obligate anaerobes are symbiotic microorganisms that inhabit the human microbiota, predominantly found on epithelial or mucosal surfaces across various anatomical regions. They can also be characterized as opportunistic pathogens that cause …
Community-acquired pneumonia (CAP) is among the most frequent causes of hospitalization worldwide and the associated mortality remains high [ 1 , 2 ]. Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 …
verfasst von:
Hans-Jakob Meyer, Lukas Mödl, Olesya Unruh, Weiwei Xiang, Sarah Berger, Moritz Müller-Plathe, Gernot Rohde, Mathias W. Pletz, Jan Rupp, Norbert Suttorp, Martin Witzenrath, Thomas Zoller, Mirja Mittermaier, Fridolin Steinbeis, CAPNETZ study group
Unfortunately, there are some mistakes with the affiliations of the following authors, including Renfang Zhang, Li Liu, Wei Song, Yueming Shao, Zhihang Zheng, Jingna Xun, Yinzhong Shen, and Jun Chen, which should be affiliated with the “2.
Fracture-related infection (FRI) is a severe complication following bone injury that requires multiple operations or even amputation to save the patient’s life, causing a major problem for orthopedic surgeons as well as a serious social and …
verfasst von:
Petrucci Flavia, Perciballi Beatrice, Rivano Capparuccia Marco, Iaiani Giancarlo, Lo Torto Federico, Ribuffo Diego, Gumina Stefano, De Meo Daniele
Multidrug-resistant organisms pose a significant and widespread public health threat globally [ 1 ]. Among these, carbapenem-resistant Gram-negative bacilli are of particular concern. This category encompasses carbapenem-resistant Enterobacterales …
Infections are common among pregnant women. Nearly half of pregnant women experience some type of infection during their pregnancy [ 1 ]. Due to physiological changes such as altered immune tolerance for the fetus, urinary stasis, and respiratory …
verfasst von:
Jian-Rong He, Gabriella Tikellis, Ora Paltiel, Mark Klebanoff, Per Magnus, Kate Northstone, Jean Golding, Mary H. Ward, Martha S. Linet, Sjurdur F. Olsen, Gary S. Phillips, Stanley Lemeshow, Xiu Qiu, Jane E. Hirst, Terence Dwyer
Due to demographic changes and longer life expectancy, the number of joint replacements is increasing rapidly. Currently, more than 1 million arthroplasties per year are performed in the USA. A significant increase to up to four million operations …
verfasst von:
Alexander Röhrl, Frank Klawonn, Bernd Füchtmeier, Christian Wulbrand, Andre Gessner, Jozef Zustin, Andreas Ambrosch
Staphylococcus aureu s is a common human pathogen that potentially causes fatal diseases [ 1 , 2 ], including bacteremia ( S. aureu s bacteremia, SAB). Patients with SAB frequently experience systemic complications, including abscess formation …
Ocular surface squamous neoplasia (OSSN) is an umbrella term that describes a spectrum of pre-malignant and malignant epithelial lesions of the conjunctiva and cornea [ 1 – 4 ]. It encompasses a continuum of histological findings, namely dysplasia …
verfasst von:
Loren N. Odendaal, Corinna Andreae, Micheline Sanderson-November, Dan Zaharie, Derrick P. Smit
Chronic hepatitis B virus (HBV) infection affects more than 250 million individuals worldwide and is a major cause of liver cirrhosis and hepatocellular carcinoma (HCC) [ 1 ]. Vertical transmission from mother-to-child during delivery (MTCT) has …
verfasst von:
Anders Eilard, Maria E. Andersson, Rune Wejstål, Gunnar Norkrans, Magnus Lindh
Tuberculosis (TB) presents a significant health challenge, particularly in developing nations like India. This challenge is compounded by the emergence of multiple drug-resistant (MDR) strains, which are resistant to both rifampicin and isoniazid …
Surgical site infection (SSI) is a serious complication of dorsal spondylodesis, with significant short- and long-term consequences for patients and considerable socioeconomic burden [ 1 , 2 ]. Despite attempts to develop SSI risk stratification …
verfasst von:
Paul Jonathan Roch, Carolin Ecker, Katharina Jäckle, Marc-Pascal Meier, Maximilian Reinhold, Friederike Sophie Klockner, Wolfgang Lehmann, Lukas Weiser
Coronavirus disease 2019 (COVID-19) is a contagious pneumonia-like illness caused by the coronavirus 2 severe acute respiratory syndrome (SARS-CoV-2). The first outbreak was identified in December 2019 in Wuhan, China, and it rapidly spread …
verfasst von:
Gamalat A. Elgedawy, Naglaa S. Elabd, Radwa H. Salem, Samah M. Awad, Amany A. Amer, Mohammad M. Torayah, Amal A. El-Koa, Mai Abozeid, Belal A. Montaser, Hind S. Aboshabaan, Mervat Abdelkreem, Marwa L. Helal
