Ausgabe 1/2024
Inhalt (71 Artikel)
Pharmacological properties of Polygonatum and its active ingredients for the prevention and treatment of cardiovascular diseases
Hongyuan Lin, Wenhui Wang, Mengqi Peng, Yifan Kong, Xiaowei Zhang, Xiaohong Wei, Hongcai Shang
Machine learning integration of multi-modal analytical data for distinguishing abnormal botanical drugs and its application in Guhong injection
Zhu Han, Jiandong Zhao, Yu Tang, Yi Wang
Combination of Atractylenolide I, Atractylenolide III, and Paeoniflorin promotes angiogenesis and improves neurological recovery in a mouse model of ischemic Stroke
Haiyan Li, Wantong Yu, Yong Yang, Sijie Li, Jun Xu, Chen Gao, Wei Zhang, Wenjie Shi, Kunlin Jin, Xunming Ji, Changhong Ren
Interfering with the AKT/mTOR/STAT3/ID1 signaling axis with usenamine A restrains the proliferative and invasive potential of human hepatocellular carcinoma cells
Ailin Yang, Huiming Huang, Jinxin Xie, Yingying Tian, Longyan Wang, Dongxiao Liu, Xuejiao Wei, Peng Tan, Xingyun Chai, Xiaojun Zha, Pengfei Tu, Zhongdong Hu
Combination of mangiferin and T0901317 targeting autophagy promotes cholesterol efflux from macrophage foam cell in atherosclerosis
Qian Chen, Sijian Wang, Ruixia Bao, Dan Wang, Yuzheng Wu, Yi Zhang, Mengyang Liu, Tao Wang
Prunella vulgaris polysaccharide inhibits herpes simplex virus infection by blocking TLR-mediated NF-κB activation
Xuanlei Zhong, Yibo Zhang, Man Yuan, Lin Xu, Xiaomei Luo, Rong Wu, Zhichao Xi, Yang Li, Hongxi Xu
Sanguinarine chloride induces ferroptosis by regulating ROS/BACH1/HMOX1 signaling pathway in prostate cancer
Shanhui Liu, Yan Tao, Shan Wu, Jiawei Lin, Shengjun Fu, Jianzhong Lu, Jing Zhang, Beitang Fu, Erdong Zhang, Jing Xu, Jiaxuan Wang, Lanlan Li, Lei Zhang, Zhiping Wang
Effects and mechanisms of Zhizi Chuanxiong herb pair against atherosclerosis: an integration of network pharmacology, molecular docking, and experimental validation
Yan Zhang, Yifei Qi, Zijun Jia, Yiming Li, Liqi Wu, Qingbing Zhou, Fengqin Xu
Regulation of polysaccharide in Wu‐tou decoction on intestinal microflora and pharmacokinetics of small molecular compounds in AIA rats
Di Yang, Xiaoxu Cheng, Meiling Fan, Dong Xie, Zhiqiang Liu, Fei Zheng, Yulin Dai, Zifeng Pi, Hao Yue
Modified Qing-Zao-Jiu-Fei decoction attenuated pulmonary fibrosis induced by bleomycin in rats via modulating Nrf2/NF-κB and MAPKs pathways
Jia-Qian Zhu, Yuan-Yang Tian, Kam Leung Chan, Zhen Hu, Qing-Qing Xu, Zhi-Xiu Lin, Yan-Fang Xian
Quercetin inhibits caspase-1-dependent macrophage pyroptosis in experimental folic acid nephropathy
Xianli Gao, Caiyun Guo, Wenjun Li, Yingdong Deng, Wenjun Ning, Jiaqi Xie, Xiaoying Zhan, Youling Fan, Hongtao Chen, Zengping Huang, Jun Zhou
The SIRT1/Nrf2 signaling pathway mediates the anti-pulmonary fibrosis effect of liquiritigenin
Qingzhong Hua, Lu Ren
Osteoking promotes bone formation and bone defect repair through ZBP1–STAT1–PKR–MLKL-mediated necroptosis
Suya Zhang, Yudong Liu, Zhaochen Ma, Shuangrong Gao, Lin Chen, Honggang Zhong, Chu Zhang, Tao Li, Weiheng Chen, Yanqiong Zhang, Na Lin
Interpreting the efficacy enhancement mechanism of Chinese medicine processing from a biopharmaceutic perspective
Bing Yang, Zhubin Zhang, Jinjing Song, Tianhao Qi, Jingqi Zeng, Liang Feng, Xiaobin Jia
The effects of Chinese proprietary medicine and vaccination on patients with COVID-19: a retrospective study in Macao
Hui Mo, Man-Fei Zhou, Edmundo Patricio Lopes Lao, Ka-Kei Chan, On-Na Lai, Man-In Ho, Kin-Wa Wong, Ka-Meng Ho, Kin-Tim Sio, Keng-Lam Fong, Yong-Hua Zhao, Seng-Ip Cheang, Iek-Long Lo
Ganoderma lucidum polysaccharide ameliorates cholesterol gallstone formation by modulating cholesterol and bile acid metabolism in an FXR-dependent manner
Dan Huang, Shuang Shen, Qian Zhuang, Xin Ye, Yueqin Qian, Zhixia Dong, Xinjian Wan
Comprehensive review of dibenzocyclooctadiene lignans from the Schisandra genus: anticancer potential, mechanistic insights and future prospects in oncology
Karolina Jafernik, Sara Motyka, Daniela Calina, Javad Sharifi-Rad, Agnieszka Szopa
Zhuifeng Tougu capsules in the treatment of knee osteoarthritis (cold dampness obstruction syndrome): a randomized, double blind, multicenter clinical study
Longmei Zhao, Shasha Zhou, SiWei Wang, Rui Wu, Qingliang Meng, Zhenbin Li, Jiangyun Peng, Ying Liu, Min Lu, Ming Li, Caifeng Zhu, Yue Sun, Yanlin He, Yue Jin, Jingyue Gao, Shumin Zhang, Peihao Li, Rongjun Liao, Wei Liu, Guoming Zhang
Decoction regulating phytochemicals’ micromorphology changes and anti-inflammation activity enhancements originated from herb medicine supermolecules
Luping Yang, Xiang Zhang, Zhijia Wang, Xiaoyu Lin, Yaozhi Zhang, Jihui Lu, Linying Wu, Shuchang Yao, Wenguang Jing, Xuemei Huang, Penglong Wang
Gromwell ameliorates glucocorticoid-induced muscle atrophy through the regulation of Akt/mTOR pathway
Ahyoung Yoo, Jung-In Kim, Hyunjung Lee, Farida S. Nirmala, Jeong-Hoon Hahm, Hyo Deok Seo, Chang Hwa Jung, Tae Youl Ha, Jiyun Ahn
Integrated traditional Chinese and Western medicine in the prevention and treatment of non-alcoholic fatty liver disease: future directions and strategies
Xin Ding, Xu He, Bulang Tang, Tian Lan
Identification and expression analysis of expansin gene family in Salvia miltiorrhiza
Yunyun Li, Bin Li, Qiyue Pang, Yaoyu Lou, Donghao Wang, Zhezhi Wang
Comparative transcriptome analysis and identification of candidate R2R3-MYB genes involved in anthraquinone biosynthesis in Rheum palmatum L.
Xia Zhao, Feng Yan, Yi-min Li, Jing Tang, Xiao-chen Hu, Zhao Feng, Jing Gao, Liang Peng, Gang Zhang
Tanreqing injection inhibits dengue virus encephalitis by suppressing the activation of NLRP3 inflammasome
Hefei Huang, Xuemei He, Lingzhu Shi, Jingtao Yu, Zibin Lu, Huihui Cao, Jinying Ou, Xi Chen, Lijun Yan, Jiabin Yang, Wei Zhao, Junshan Liu, Linzhong Yu
Natural products in osteoarthritis treatment: bridging basic research to clinical applications
Shunzheng Fang, Bin Zhang, Wei Xiang, Liujie Zheng, Xiaodong Wang, Song Li, Tongyi Zhang, Daibo Feng, Yunquan Gong, Jinhui Wu, Jing Yuan, Yaran Wu, Yizhen Zhu, Enli Liu, Zhenhong Ni
Paclitaxel combined with Compound K inducing pyroptosis of non-small cell lung cancer cells by regulating Treg/Th17 balance
Hongzheng Wang, Min Huang, Mengyuan Zhu, Chi Su, Yijian Zhang, Hongyu Chen, Yuexin Jiang, Haidi Wang, Qinglong Guo, Shuai Zhang
Total flavonoids of Astragalus protects glomerular filtration barrier in diabetic kidney disease
Pei-Yu Liu, Kin-Fong Hong, Ya-Di Liu, Zhong-Yan Sun, Ting-Ting Zhao, Xu-Ling Li, Chi-Chou Lao, Shu-Feng Tan, Hai-Ying Zhang, Yong-Hua Zhao, Ying Xie, You-Hua Xu
Immunopotentiating effects of herb-partitioned moxibustion on the spleens of cyclophosphamide-induced immunosuppressed rats
Luojie Xiong, Yuefeng Tian, Xiaoshan Xu, Huifang Wang, Wei Li, Chuntao Zhai
Exploring the chemical components of Kuanchang-Shu granule and its protective effects of postoperative ileus in rats by regulating AKT/HSP90AA1/eNOS pathway
Wen-Qian Duan, Ming-Chen Cai, Qi-Qi Ma, Peng Huang, Jia-Hui Zhang, Tian-Fu Wei, Dong Shang, Ai-Jing Leng, Jia-Lin Qu
Optimized New Shengmai Powder modulation of cAMP/Rap1A signaling pathway attenuates myocardial fibrosis in heart failure
Zeyu Zhang, Zhe xu, Shuai Wang, Zhuangzhuang Jia, Zhou zhou, Ci Wang, Shanshan Lin, Yiting Feng, Xianliang Wang, Jingyuan Mao
SKP alleviates the ferroptosis in diabetic kidney disease through suppression of HIF-1α/HO-1 pathway based on network pharmacology analysis and experimental validation
Yangtian Yan, Ningning Yuan, Yuchi Chen, Yun Ma, Ali Chen, Fujing Wang, Shihua Yan, Zhuo’en He, Jinyue He, Chi Zhang, Hao Wang, Mingqing Wang, Jianxin Diao, Wei Xiao
Bufei Yishen formula protects the airway epithelial barrier and ameliorates COPD by enhancing autophagy through the Sirt1/AMPK/Foxo3 signaling pathway
Lidan Jia, Xuefang Liu, Xinguang Liu, Qingzhou Guan, Yange Tian, Jiansheng Li, Peng Zhao
Determination of ITS1 haplotypes of Fritillariae Cirrhosae Bulbus by amplicon sequencing
Hoi-Yan Wu, Ka-Lok Wong, Sean Tsz-Sum Law, Wenyang Nong, Kwun-Tin Chan, Jerome Ho-Lam Hui, Ge Lin, Wing-Han Chan, Pang-Chui Shaw
The combination of Tanshinone IIA and Astragaloside IV attenuates myocardial ischemia–reperfusion injury by inhibiting the STING pathway
Pan Zhai, Qianyun Chen, Xunxun Wang, Xiaohu Ouyang, Mengling Yang, Yalan Dong, Junyi Li, Yiming Li, Shanshan Luo, Yue Liu, Xiang Cheng, Rui Zhu, Desheng Hu
A review on traditional Chinese medicine natural products and acupuncture intervention for Alzheimer’s disease based on the neuroinflammatory
Zhihan Chen, Xinrui Wang, Simin Du, Qi Liu, Zhifang Xu, Yi Guo, Xiaowei Lin
A novel network pharmacology strategy to decode mechanism of Wuling Powder in treating liver cirrhosis
Qinwen Liu, Xiaowei Li, Yi Li, Qian Luo, Qiling Fan, Aiping Lu, Daogang Guan, Jiahui Li
Trachelogenin alleviates osteoarthritis by inhibiting osteoclastogenesis and enhancing chondrocyte survival
Tao Jiang, Jiahui Zhang, Beite Ruan, Xiaobing Xi, Zhuo Yang, Jianmin Liu, Hongyan Zhao, Xing Xu, Min Jiang
Traditional Chinese Medicine Shi-Bi-Man ameliorates psoriasis via inhibiting IL-23/Th17 axis and CXCL16-mediated endothelial activation
Chenyang Zhang, Xinran Cao, Lixin Zhao, Zitong Ni, Haojie Du, Jiao Qu, Jianxia Zhu, Haiyan Sun, Yang Sun, Zijun Ouyang
Golden bile powder prevents drunkenness and alcohol-induced liver injury in mice via the gut microbiota and metabolic modulation
Yarong Wang, Zhenzhuang Zou, Sihua Wang, Airong Ren, Zhaolin Ding, Yingying Li, Yifang Wang, Zhengming Qian, Baolin Bian, Bo Huang, Guiwei Xu, Guozhen Cui
Platycodon D protects human nasal epithelial cells from pyroptosis through the Nrf2/HO-1/ROS signaling cascade in chronic rhinosinusitis
Ruizhi Wang, Yongchun Wang, He Liu, Jinxiang Zhu, Caishan Fang, Weizhen Xu, Zesheng Lu, Yajie Yan, Weiping He, Yan Ruan, Min Zhou
LanGui tea, an herbal medicine formula, protects against binge alcohol-induced acute liver injury by activating AMPK-NLRP3 signaling
Ming Gu, Yu-jun Chen, Ya-ru Feng, Zhi-peng Tang
Cayratia albifolia C.L.Li exerts anti-rheumatoid arthritis effect by inhibiting macrophage activation and neutrophil extracellular traps (NETs)
Wei Wang, Zai-Qi Zhang, Yi-Chi Zhang, Yi-Qiang Wu, Zhuo Yang, Yong-Zhe Zheng, Jia-Hong Lu, Peng-Fei Tu, Ke-Wu Zeng
Electroacupuncture pretreatment mediates sympathetic nerves to alleviate myocardial ischemia–reperfusion injury via CRH neurons in the paraventricular nucleus of the hypothalamus
Jie Zhou, Bin Zhang, Xiang Zhou, Fan Zhang, Qi Shu, Yan Wu, Hui-Min Chang, Ling Hu, Rong-Lin Cai, Qing Yu
A multi-center cross-sectional study of Chinese Herbal Medicine-Drug adverse reactions using active surveillance in Singapore’s Traditional Chinese Medicine clinics
Chester Yan Jie Ng, Yan Zhao, Ning Wang, Kwan Leung Chia, Chun Huat Teo, William Peh, Pansy Yeo, Linda L. D. Zhong
Cryptotanshinone inhibits PFK-mediated aerobic glycolysis by activating AMPK pathway leading to blockade of cutaneous melanoma
Qiong Chen, Yang Liu, Yunxuan Zhu, Ziyan Zhu, Jueyao Zou, Yanhong Pan, Yin Lu, Wenxing Chen
Salvianolic acid C attenuates cerebral ischemic injury through inhibiting neuroinflammation via the TLR4-TREM1-NF-κB pathway
Wenbo Guo, Xiaojing Xu, Yulin Xiao, Jiatian Zhang, Peiqiang Shen, Xiaoyan Lu, Xiaohui Fan
Chinmedomics: a potent tool for the evaluation of traditional Chinese medicine efficacy and identification of its active components
Mengmeng Wang, Fengting Yin, Ling Kong, Le Yang, Hui Sun, Ye Sun, Guangli Yan, Ying Han, Xijun Wang
The combination of Schisandrin C and Luteolin synergistically attenuates hepatitis B virus infection via repressing HBV replication and promoting cGAS-STING pathway activation in macrophages
Zhixin Wu, Xiaomei Zhao, Ruisheng Li, Xinru Wen, Ye Xiu, Minjuan Long, Junjie Li, Xiuqin Huang, Jincai Wen, Xu Dong, Yingjie Xu, Zhaofang Bai, Xiaoyan Zhan, Xiaohe Xiao
Recent advances in the potential effects of natural products from traditional Chinese medicine against respiratory diseases targeting ferroptosis
Tian Chen, Lu Ding, Meiru Zhao, Siyu Song, Juan Hou, Xueyan Li, Min Li, Kai Yin, Xiangyan Li, Zeyu Wang
TCMNPAS: a comprehensive analysis platform integrating network formulaology and network pharmacology for exploring traditional Chinese medicine
Yishu Liu, Xue Li, Chao Chen, Nan Ding, Peiyong Zheng, Xiaoyun Chen, Shiyu Ma, Ming Yang
Chemodiversity, pharmacological activity, and biosynthesis of specialized metabolites from medicinal model fungi Ganoderma lucidum
Yupeng Du, Lixia Tian, Yu Wang, Zhenhao Li, Zhichao Xu
Juglone induces ferroptosis in glioblastoma cells by inhibiting the Nrf2-GPX4 axis through the phosphorylation of p38MAPK
Fangzhou Guo, Guoyuan Ling, Jianting Qiu, Jicheng Li, Yu Gan, YingYing Yu, Jiamei Tang, Ligen Mo, Haozhe Piao
Total iridoid glycoside extract of Lamiophlomis rotata (Benth) Kudo accelerates diabetic wound healing by the NRF2/COX2 axis
Xiaoyu Geng, Ying Wang, Huan Li, Liang Song, Chen Luo, Xiaojie Gu, Haixin Zhong, Huilin Chen, Xinzhu Chen, Jianwei Wang, Zheng Pan
Cordyceps sinensis relieves non-small cell lung cancer by inhibiting the MAPK pathway
Tianming Lu, Lirun Zhou, Zheng Chu, Yang Song, Qixin Wang, Minghong Zhao, Chuanhao Dai, Lin Chen, Guangqing Cheng, Jigang Wang, Qiuyan Guo
Formononetin reverses Treg/Th17 imbalance in immune-mediated bone marrow failure mice by regulating the PI3K/Akt signaling pathway
Huixuan Lan, Wei Qiu, Jie Wu, Zhijing Hu, Xiaomin Zhang, Lingling Zhu
Medicinal plants and natural products for treating overactive bladder
Huanxian Chen, Maggie Pui Man Hoi, Simon Ming Yuen Lee
Natural products as potential drug treatments for acute promyelocytic leukemia
Jiaxin Chen, Zuoqi Ding
Danggui Sini decoction alleviates oxaliplatin-induced peripheral neuropathy by regulating gut microbiota and potentially relieving neuroinflammation related metabolic disorder
Chen Chen, Jian-Lin Xu, Zhan-Cheng Gu, Shan-Shan Zhou, Guo-Li Wei, Jia-Lin Gu, Hai-Long Ma, Yan-Qi Feng, Zi-Wei Song, Zhan-Peng Yan, Shan Deng, Rong Ding, Song-Lin Li, Jie-Ge Huo
Oleuropein alleviates myocardial ischemia–reperfusion injury by suppressing oxidative stress and excessive autophagy via TLR4/MAPK signaling pathway
Jia He, Liting Huang, Kaili Sun, Jilang Li, Shan Han, Xiang Gao, Qin-Qin Wang, Shilin Yang, Wen Sun, Hongwei Gao
NBR1-p62-Nrf2 mediates the anti-pulmonary fibrosis effects of protodioscin
Qian Zeng, Bin-bin Wen, Xin Liu, Yong-yu Luo, Zhen-gang Hu, Lei Huang, Xiao-hua Zhang, Xiao-ting Huang, Ting-ting Zhou, Xiao-xue Sang, Yu-yang Luo, Da-yan Xiong, Zi-qiang Luo, Wei Liu, Si-yuan Tang
Bazi Bushen ameliorates age-related energy metabolism dysregulation by targeting the IL-17/TNF inflammatory pathway associated with SASP
Xiaogang Shen, Mengnan Li, Yawen Li, Yuning Jiang, Kunxu Niu, Shixiong Zhang, Xuan Lu, Runtao Zhang, Zhiqin Zhao, Liangxing Zhou, Zhifang Guo, Siwei Wang, Cong Wei, Liping Chang, Yunlong Hou, Yiling Wu
Compound Shenma Jingfu granule alleviates cerebral ischemia via HIF-1α-mediated promotion of angiogenesis
Ruihua He, Yi Xu, Jingxue Liu, Jing Liu, Jing Chen, Xufang Wang, Lei Qiu, Jin Huang
“Qi Nan” agarwood restores podocyte autophagy in diabetic kidney disease by targeting EGFR signaling pathway
Ning Li, Xuenan Liu, Hao Wang, Yingling Duan, Yu Zhang, Ping Zhou, Haofu Dai, Tian Lan
Metabolite identification of salvianolic acid A in rat using post collision-induced dissociation energy-resolved mass spectrometry
Han Li, Ke Zhang, Wei Chen, Yuxuan Zhou, Jun Li, Yunfang Zhao, Yuelin Song
Integration of metabolomics and transcriptomics reveals the therapeutic mechanism underlying Chelidonium majus L. in the treatment of allergic asthma
Renguang Wang, Xintong Sui, Xin Dong, Liming Hu, Zhimeng Li, Hang Yu, Cuicui Li, Guoxin Ji, Shumin Wang
Traditional uses, phytochemistry, pharmacology, quality control and clinical studies of Cimicifugae Rhizoma: a comprehensive review
Qianqian Zhang, Wei Wei, Xingyue Jin, Jin Lu, Shujing Chen, Omachi Daniel Ogaji, Shaoxia Wang, Kunze Du, Yanxu Chang, Jin Li
Systematic investigation of the material basis, effectiveness and safety of Thesium chinense Turcz. and its preparation Bairui Granules against lung inflammation
Guang-Cheng Peng, Jin-Hua Hao, Yue-Qin Guan, Ying-Yue Wang, Ming-Jie Liu, Guo-Hui Li, Zhen-Peng Xu, Xue-Sen Wen, Tao Shen
Acacetin alleviates autoimmune myocarditis by regulating CD4+ T cell mitochondrial respiration
Yang Lu, Yu-Wei Wu, Jiu Pu, Qiong-Feng Wu, Qian Dong, Ning Zhao, Gui-Rong Li, Yi-Mei Du
Cirsilineol inhibits RANKL-induced osteoclast activity and ovariectomy-induced bone loss via NF-κb/ERK/p38 signaling pathways
Cong Wang, Rong Zeng, Yong Li, Rongxin He
Gynostemma Pentaphyllum ameliorates CCl4-induced liver injury via PDK1/Bcl-2 pathway with comprehensive analysis of network pharmacology and transcriptomics
Linlan Hu, Xin Zhao, Xian He, Yafei Guo, Hanxiao Cheng, Shaoting Chen, Guangde Zhou, Jiabo Wang, Yawen Lu
Development of an interpretable machine learning model associated with genetic indicators to identify Yin-deficiency constitution
Jing Li, Yingying Zhai, Yanqi Cao, Yifan Xia, Ruoxi Yu