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15797 Suchergebnisse für:

Pseudomonas aeruginosa 

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  1. Open Access 01.12.2024 | OriginalPaper

    Rapid, sensitive, and user-friendly detection of Pseudomonas aeruginosa using the RPA/CRISPR/Cas12a system

    Pseudomonas aeruginosa ( P. aeruginosa ) belongs to the Pseudomonadaceae family and is a Gram-negative, aerobic, opportunistic pathogenic bacterium known for its remarkable adaptability and antibiotic resistance. It is ubiquitously found in various …

  2. Open Access 01.12.2024 | ReviewPaper

    Prevalence of meropenem-resistant Pseudomonas Aeruginosa in Ethiopia: a systematic review and meta‑analysis

    Antimicrobial resistance (AMR) is a leading cause of death around the world, with the highest burdens in low-resource settings [ 1 ]. Antimicrobial resistance can be stated as the innate or acquired capacity of a microbe to impede the effectiveness …

  3. Open Access 15.05.2024 | Online First

    Extendin-4 blockade of T1R2/T1R3 activation improves Pseudomonas aeruginosa-related pneumonia in an animal model of chemically induced diabetes

    Diabetes mellitus (DM) is a rapidly growing global endemic disease and is generally accepted as an independent risk factor for lower respiratory tract infections [ 1 , 2 ]. Accumulating investigations have revealed that compared to a healthy lung …

  4. 03.02.2024 | OriginalPaper

    Quercetin attenuates Pseudomonas aeruginosa-induced acute lung inflammation by inhibiting PI3K/AKT/NF-κB signaling pathway

    Pseudomonas aeruginosa is an opportunistic pathogen that commonly causes infections in immunocompromised individuals with significant morbidity and mortality. Quercetin is a natural flavonoid abundantly present in fruits and vegetables, exerting …

  5. Open Access 23.02.2024 | OriginalPaper

    Surgical Treatment of Persistent Pseudomonas aeruginosa Bacteraemia After n-Butyl-2-cyanoacrylate for Gastric Bleeding Varices

    n-Butyl-2-cyanoacrylate (NCBA) is an effective therapeutic option for bleeding gastric varices but can sometimes be associated with adverse effects. Persistent bacteraemia is an unusual complication with a high mortality rate. We report the case …

  6. Open Access 01.12.2024 | OriginalPaper

    Effectiveness of Umonium38 against Burkholderia pseudomallei, Escherichia coli, Pseudomonas aeruginosa and Methicillin-Resistant Staphylococcus aureus (MRSA)

    Effective disinfection is crucial for infection control as it helps to control potentially hazardous microorganisms, especially in laboratory environments. It is crucial to use validated decontamination protocols to effectively inactivate …

  7. Open Access 18.01.2024 | OriginalPaper

    Molecular analysis of metallo-beta-lactamase-producing Pseudomonas aeruginosa in Switzerland 2022–2023

    Pseudomonas aeruginosa is a major cause of nosocomial infections, particularly in immune-compromised patients, and is associated with considerable morbidity and mortality [ 1 , 2 ]. The increasing global incidence of carbapenem-resistant P.

  8. Open Access 29.12.2023 | OriginalPaper

    Activity of imipenem/relebactam and comparators against KPC-producing Klebsiella pneumoniae and imipenem-resistant Pseudomonas aeruginosa

    Carbapenem-resistant Gram-negative bacilli (CRGNB) are a major public health problem, recently described by WHO as a global crisis [ 1 ]. Since nosocomial and healthcare-associated infections caused by CRGNB organisms significantly increase …

  9. 10.01.2024 | OriginalPaper

    Population-based genomic surveillance of Pseudomonas aeruginosa causing bloodstream infections in a large Canadian health region

    Pseudomonas aeruginosa ranks among the top ten bacterial causes of bloodstream infections (BSIs) globally [ 1 , 2 ]. Overall, it is responsible for between 4 and 9% of culture-positive bacterial BSIs [ 1 – 3 ]. P. aeruginosa BSIs are linked with …

  10. Open Access 01.12.2024 | OriginalPaper

    Clinical success of anti-infective combination therapy compare to monotherapy in patients with carbapenem-resistant Pseudomonas aeruginosa infection: a 10-years retrospective study

    Pseudomonas aeruginosa ( P. aeruginosa ) is a ubiquitous microorganism that causes different types of infections, primarily in immunosuppressed patients, critical care patients, or those with comorbidities [ 1 ]. P. aeruginosa is also one of the …

  11. Open Access 01.12.2024 | OriginalPaper

    Fine particulate matter 2.5 induces susceptibility to Pseudomonas aeruginosa infection via expansion of PD-L1high neutrophils in mice

    Air pollution poses a serious global public health threat [ 1 ]. Particulate matter (PM) is among the most harmful air pollutants, including PM10, PM2.5, and ultrafine particles. PM10 particles are coarse, with an aerodynamic diameter of less than …

  12. Open Access 24.01.2024 | OriginalPaper

    Genomic epidemiology and molecular characteristics of blaNDM-1-positive carbapenem-resistant Pseudomonas aeruginosa belonging to international high-risk clone ST773 in the Gauteng region, South Africa

    Pseudomonas aeruginosa is an important opportunistic pathogen causing a wide range of healthcare-associated infections, including ventilator-associated pneumonia, catheter-associated urinary tract, surgical site, burn wound and bloodstream …

  13. 19.01.2024 | OriginalPaper

    Performance evaluation of Bruker UMIC® microdilution panel and disc diffusion to determine cefiderocol susceptibility in Enterobacterales, Acinetobacter baumannii, Pseudomonas aeruginosa, Stenotrophomonas maltophilia, Achromobacter xylosoxidans and Burkolderia species

    Cefiderocol is a recently approved cephalosporin exhibiting potent activity towards a broad spectrum of aerobic Gram-negative multi-drug-resistant (MDR) pathogens, including carbapenemase-producers. A recent meta-analysis showed that the …

  14. 28.02.2024 | Online First

    Successful treatment of sino-pulmonary infection & skull base osteomyelitis caused by New Delhi metallo-β-lactamase-producing Pseudomonas aeruginosa in a renal transplant recipient by using an investigational antibiotic cefepime/zidebactam (WCK 5222)

    A case of sino-pulmonary infection with skull base osteomyelitis due to XDR-Pseudomonas aeruginosa in renal transplant recipient was successfully treated with investigational antibiotic, cefepime/zidebactam (WCK 5222). This case highlights …

  15. Open Access 01.12.2023 | OriginalPaper

    Acarbose reduces Pseudomonas aeruginosa respiratory tract infection in type 2 diabetic mice

    According to the International Diabetes Federation and the World Health Organization, as of 2021, approximately one in ten people worldwide have diabetes, with a total of 537 million diabetics [ 1 , 2 ]. Diabetes mellitus prevalence has been …

  16. Open Access 01.12.2023 | OriginalPaper

    Coronavirus disease 2019 (COVID-19)-associated brain abscesses caused by Pseudomonas aeruginosa and Aspergillus fumigatus: two case and a review of the literature

    The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has affected over 505 million people and had caused 6.2 million deaths worldwide by 23 April 2022 [ 1 ]. Bacterial and fungal …

  17. Open Access 01.12.2023 | OriginalPaper

    A score to predict Pseudomonas aeruginosa infection in older patients with community-acquired pneumonia

    Community-acquired pneumonia (CAP) is lung infection that started outside the hospital or within 48 h of hospital admission [ 1 ]. It is a prevalent infectious disease affecting the elderly, with more than 30–40% of cases hospitalized [ 2 ].

  18. Open Access 01.12.2023 | Letter

    Monotherapy or combination antibiotic therapy in the treatment of Pseudomonas aeruginosa ventilator-associated pneumonia

  19. Open Access 01.12.2023 | OriginalPaper

    Successful treatment of multidrug-resistant Pseudomonas aeruginosa keratitis with meropenem eye drops — a case report

    Pseudomonas aeruginosa (P. aeruginosa) is a gram-negative, opportunistic pathogen. Due to its diverse metabolic pathways and large repertoire of pathogenic mechanisms, P. aeruginosa is able to adapt to a wide variety of environments, causing …

  20. Open Access 23.08.2023 | OriginalPaper

    A novel lytic phage exhibiting a remarkable in vivo therapeutic potential and higher antibiofilm activity against Pseudomonas aeruginosa

    Pseudomonas aeruginosa is a widely distributed opportunistic pathogen that could survive in water, soil, animals and humans [ 1 ]. P. aeruginosa causes a variety of acute and chronic infections especially in immunocompromised patients [ 2 , 3 ]. P.

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Legionellosen und andere durch Wasser übertragbare Infektionen: Risikofaktoren, Erreger und Hygienemaßnahmen

Praktische Krankenhaushygiene und Umweltschutz
Zahlreiche Infektionserreger können durch Wasser übertragen werden. Unter den in der Literatur beschriebenen Viren, Bakterien, Pilzen und Protozoen haben vier Bakterienspezies eine größere Bedeutung für die praktische Krankenhaushygiene: Legionella pneumophila sowie die drei zu den Non-Fermentern gehörenden Spezies Pseudomonas aeruginosa, Stenotrophomonas maltophilia und die Acinetobacter-baumannii-Gruppe. Ihnen gemeinsam ist, vor allem Pneumonien zu verursachen, die oft mit den üblichen Cephalosporinen zur Behandlung nosokomialer Pneumonien nicht ausreichend behandelt werden können. Übertragungen dieser Erreger können entweder über direkten Kontakt, Ingestion oder Aspiration, Einatmen von Wasseraerosolen oder über die Hände geschehen.

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