Erschienen in:
01.03.2007 | Adis Profile Report
Panitumumab in the Treatment of Metastatic Colorectal Cancer
Profile Report
verfasst von:
Sheridan M. Hoy, Antona J. Wagstaff
Erschienen in:
BioDrugs
|
Ausgabe 2/2007
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Excerpt
Approximately 655 000 deaths worldwide each year can be attributed to colorectal cancer.[
4] The primary treatment option for patients with colorectal cancer is surgery;[
5] however, approximately 50% of patients will subsequently develop metastases.[
6,
7] The prognosis for these patients is generally poor; median survival from diagnosis is 6–9 months[
8] and the 5-year survival rate is <5%.[
6] Nevertheless, quality of life, time to disease progression, and overall survival in patients with metastatic colorectal cancer can be improved with the use of chemotherapy.[
6,
7] …