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Monocyte/HDL-cholesterol ratio predicts the definite stent thrombosis after primary percutaneous coronary intervention for ST-segment elevation myocardial infarction

    Elif Hande Ozcan Cetin

    *Author for correspondence:

    E-mail Address: dr.elifhande@gmail.com

    Türkiye Yuksek Ihtisas Education & Research Hospital, Cardiology Department, Ankara, Turkey

    ,
    Mehmet Serkan Cetin

    Türkiye Yuksek Ihtisas Education & Research Hospital, Cardiology Department, Ankara, Turkey

    ,
    Uğur Canpolat

    Türkiye Yuksek Ihtisas Education & Research Hospital, Cardiology Department, Ankara, Turkey

    ,
    Selahattin Aydin

    Türkiye Yuksek Ihtisas Education & Research Hospital, Cardiology Department, Ankara, Turkey

    ,
    Serkan Topaloglu

    Türkiye Yuksek Ihtisas Education & Research Hospital, Cardiology Department, Ankara, Turkey

    ,
    Dursun Aras

    Türkiye Yuksek Ihtisas Education & Research Hospital, Cardiology Department, Ankara, Turkey

    &
    Sinan Aydogdu

    Türkiye Yuksek Ihtisas Education & Research Hospital, Cardiology Department, Ankara, Turkey

    Published Online:https://doi.org/10.2217/bmm.15.74

    Aim: We investigated the predictive value of monocyte count to HDL ratio (M/H ratio) for stent thrombosis (ST) in ST elevation myocardial infarction (STEMI). Patients & methods: 1170 STEMI patients treated with primary PCI were followed-up for a median of 37.2 months. Results: During follow-up, 112 patients were diagnosed as ‘definite’ ST. The rate of ST was significantly highest in the third M/H ratio tertile. In Cox regression analysis, adjusted for other factors, having an M/H ratio in third tertile had a 2.2-fold increased risk of ST. Kaplan–Meier analysis revealed the higher occurrence of ST in the third tertile compared with others (p <0.001). Conclusion: M/H ratio as a novel marker of inflammation seemed to be an independent predictor of ST in STEMI patients.

    Papers of special note have been highlighted as: • of interest; •• of considerable interest

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