Erschienen in:
11.05.2020 | COVID-19 | Original Paper
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COVID-19 in people living with human immunodeficiency virus: a case series of 33 patients
verfasst von:
Georg Härter, Christoph D. Spinner, Julia Roider, Markus Bickel, Ivanka Krznaric, Stephan Grunwald, Farhad Schabaz, Daniel Gillor, Nils Postel, Matthias C. Mueller, Markus Müller, Katja Römer, Knud Schewe, Christian Hoffmann
Erschienen in:
Infection
|
Ausgabe 5/2020
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Abstract
Introduction
Data on people living with human immunodeficiency virus (PLWH) in the current SARS-CoV-2 pandemic are still scarce. This case series of 33 PLWH patients with COVID-19 reveals symptoms and outcome in this special population.
Methods
Retrospective analysis of anonymized data including age, gender, HIV-associated parameters, symptoms, and outcome.
Results
Three out of 32 patients with documented outcomes died (9%). 91% of the patients recovered and 76% have been classified as mild cases. All patients were on antiretroviral treatment, of them 22 on tenofovir-containing regimen and 4 on the protease inhibitor darunavir.
Conclusions
This preliminary case series does not support excess morbidity and mortality among symptomatic COVID-19 PLWH and with viral suppression on ART. SARS-CoV-2 infections may occur during boosted darunavir-based and/or on tenofovir-containing ART.