Erschienen in:
01.06.2012 | Editorial
The effect of caffeine on adenosine myocardial perfusion imaging: Time to reassess?
verfasst von:
Fadi G. Hage, MD, FACC, Ami E. Iskandrian, MD, MACC
Erschienen in:
Journal of Nuclear Cardiology
|
Ausgabe 3/2012
Einloggen, um Zugang zu erhalten
Excerpt
“There was no significant relationship between the extent of adenosine-induced coronary flow heterogeneity and serum concentration of caffeine or its principal metabolites. Hence, the stringent requirements for prolonged abstinence from caffeine before adenosine MPI—based on limited studies—appears ill-founded.” These were the conclusions of the study by Lee et al
1 in this issue of the Journal. The interest, confusion, and the clinical relevance of the interaction (or lack of it) between adenosine and caffeine prompted this editorial viewpoint. This discussion will focus on adenosine; important differences between adenosine and dipyridamole (used in much earlier reports) suggest caution in mixing the old and the newer data but unfortunately the current practice guidelines for “vasodilator stress testing” of “prolonged abstinence” referred to above were based on the older data. …
