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01.12.2014 | Original Article

The value of direct radionuclide cystography in the detection of vesicoureteral reflux in children with normal voiding cystourethrography

verfasst von: Reza Dalirani, Abolfazl Mahyar, Mostafa Sharifian, Masoomeh Mohkam, Nasrin Esfandiar, Azam Ghehsareh Ardestani

Erschienen in: Pediatric Nephrology | Ausgabe 12/2014

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Abstract

Background

Vesicoureteral reflux (VUR) is one of the most important risk factors for urinary tract infection (UTI). Diagnosis and treatment of VUR is important to prevent irreversible complications, such as renal scarring and chronic renal failure. This study was conducted to assess the value of direct radionuclide cystography (DRNC) in the detection of VUR in children with UTI and a normal voiding cystourethrography (VCUG).

Methods

DRNC was performed in 35 children with a normal VCUG after an episode of febrile UTI who had hydronephrosis or hydroureter, abnormal acute dimercaptosuccinic acid (DMSA) scan results and/or febrile UTI recurrence. This study was conducted in the nephrology department of Mofid Children’s Hospital, Tehran (Iran).

Results

The results were statistically analyzed. Among the 70 ureters studied, 33 (49.1 %) were observed to have VUR. Of these, 17 (51.5 %) had mild, 14 (42.4 %) moderate, and 2 (6.1 %) severe reflux. A significant relationship was observed between DRNC results and DMSA renal scan findings (P < 0.05).

Conclusions

Based on our results, we suggest that DRNC may reveal VUR despite a normal VCUG in children with hydronephrosis, abnormal acute DMSA, and/or recurrent febrile UTI.

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Titel: The value of direct radionuclide cystography in the detection of vesicoureteral reflux in children with normal voiding cystourethrography
verfasst von: Reza Dalirani
Abolfazl Mahyar
Mostafa Sharifian
Masoomeh Mohkam
Nasrin Esfandiar
Azam Ghehsareh Ardestani
Publikationsdatum: 01.12.2014
Verlag: Springer Berlin Heidelberg
Erschienen in: Pediatric Nephrology / Ausgabe 12/2014
Print ISSN: 0931-041X
Elektronische ISSN: 1432-198X
DOI: https://doi.org/10.1007/s00467-014-2871-y

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The value of direct radionuclide cystography in the detection of vesicoureteral reflux in children with normal voiding cystourethrography