nach oben

Erschienen in:

02.01.2021 | Review

Migraine in transient global amnesia: a meta-analysis of observational studies

verfasst von: Ioannis Liampas, Athanasios S. Siouras, Vasileios Siokas, Zisis Tsouris, Dimitrios Rikos, Alexandros Brotis, Athina-Maria Aloizou, Metaxia Dastamani, Efthimios Dardiotis

Erschienen in: Journal of Neurology | Ausgabe 1/2022

Einloggen, um Zugang zu erhalten

Abstract

Background

Purpose

Although many studies have investigated the relationship between transient global amnesia (TGA) and migraine, to date, no meta-analysis has confirmed the existence and size of their association.

Methodology

Literature search involved MEDLINE, EMBASE, CENTRAL and PsycINFO. Observational controlled studies including TGA patients (Caplan, Hodges and Warlow) were retrieved. Quality evaluation was based on the Newcastle-Ottawa scale. The prevalence of migraine was compared in TGA patients vs. healthy controls (HC), as well as in TGA against TIA individuals. Data from case-control, cross-sectional and cohort studies were pooled separately.

Results

Literature search yielded 1178 articles, 12 of which were included in the present meta-analysis. Results from case-control (ten), cohort (one) and cross-sectional (one) studies were compatible with an association between TGA and migraine. The nationwide inpatient cross-sectional study was of lesser value due to its inpatient orientation. The high-quality, population-based, retrospective cohort (158,301 participants per group) determined a higher relative-risk (RR) of TGA for migraine vs. non-migraine individuals [RR = 2.48, 95%confidence-interval (95% CI) = (1.32, 4.87)]. Sensitivity testing based on stricter diagnostic criteria strengthened the estimated association [RR = 3.84, 95% CI = (1.57, 9.38)]. Additionally, pooled data from eight case–control studies (700 TGA, 746 HC) yielded similar results [Odds-Ratio, OR = 2.51, 95% CI = (1.85, 3.41)], with the association mainly driven by the three high-quality studies, rather than the five articles of moderate quality. Finally, pooled findings from four case–control studies of moderate-quality revealed a higher prevalence of migraine among TGA compared to TIA patients [OR = 1.82, 95% CI = (1.22, 2.73)].

Conclusions

A significant association between TGA and migraine was established. The underlying connecting mechanism remains undetermined, yet.

Nur mit Berechtigung zugänglich

Bartsch T, Butler C (2013) Transient amnesic syndromes. Nat Rev Neurol 9(2):86–97. https://doi.org/10.1038/nrneurol.2012.264CrossRefPubMed

Kirshner HS (2011) Transient global amnesia: a brief review and update. Curr Neurol Neurosci Rep 11(6):578–582. https://doi.org/10.1007/s11910-011-0224-9CrossRefPubMed

Hodges JR, Warlow CP (1990) Syndromes of transient amnesia: towards a classification: a study of 153 cases. J Neurol Neurosurg Psychiatry 53(10):834–843CrossRef

Hodges JR, Warlow CP (1990) The aetiology of transient global amnesia. A case-control study of 114 cases with prospective follow-up. Brain 113(Pt 3):639–657. https://doi.org/10.1093/brain/113.3.639CrossRefPubMed

Förster A, Griebe M, Gass A, Kern R, Hennerici MG, Szabo K (2012) Diffusion-weighted imaging for the differential diagnosis of disorders affecting the hippocampus. Cerebrovasc Dis 33(2):104–115. https://doi.org/10.1159/000332036CrossRefPubMed

Bartsch T, Alfke K, Stingele R et al (2006) Selective affection of hippocampal CA-1 neurons in patients with transient global amnesia without long-term sequelae. Brain 129(Pt 11):2874–2884. https://doi.org/10.1093/brain/awl248CrossRefPubMed

Bartsch T, Deuschl G (2010) Transient global amnesia: functional anatomy and clinical implications. Lancet Neurol 9(2):205–214. https://doi.org/10.1016/S1474-4422(09)70344-8CrossRefPubMed

Fisher CM, Adams RD (1958) Transient global amnesia. Trans Am Neurol Assoc 83(143–6):5

Fisher CM, Adams RD (1964) Transient global amnesia. Acta Neurol Scand 40(Suppl 9):1–83

10.

Jaffe R, Bender MB (1996) E.E.G. studies in the syndrome of isolated episodes of confusion with amnesia “transient global amnesia.” J Neurol Neurosurg Psychiatr. 29:472–474CrossRef

11.

Morris KA, Rabinstein AA, Young NP (2020) Factors associated with risk of recurrent transient global amnesia. JAMA Neurol. 77(12):1551. https://doi.org/10.1001/jamaneurol.2020.2943 ([published online ahead of print, 2020 Aug 31])CrossRefPubMed

12.

Quinette P, Constans JM, Hainselin M, Desgranges B, Eustache F, Viader F (2015) Hippocampal modifications in transient global amnesia. Rev Neurol (Paris) 171(3):282–288. https://doi.org/10.1016/j.neurol.2015.01.003CrossRef

13.

Mathew NT, Meyer JS (1974) Pathogenesis and natural history of transient global amnesia. Stroke 5:303–311CrossRef

14.

Arena JE, Brown RD, Mandrekar J, Rabinstein AA (2017) Long-term outcome in patients with transient global amnesia: a population-based study. Mayo Clin Proc 92(3):399–405. https://doi.org/10.1016/j.mayocp.2016.11.015CrossRefPubMed

15.

Romero JR, Mercado M, Beiser AS et al (2013) Transient global amnesia and neurological events: the framingham heart study. Front Neurol. 4:47. https://doi.org/10.3389/fneur.2013.00047 (Published 2013 May 14)CrossRefPubMedPubMedCentral

16.

Mangla A, Navi BB, Layton K, Kamel H (2014) Transient global amnesia and the risk of ischemic stroke. Stroke 45(2):389–393. https://doi.org/10.1161/STROKEAHA.113.003916CrossRefPubMed

17.

Pantoni L, Bertini E, Lamassa M, Pracucci G, Inzitari D (2005) Clinical features, risk factors, and prognosis in transient global amnesia: a follow-up study. Eur J Neurol 12(5):350–356. https://doi.org/10.1111/j.1468-1331.2004.00982.xCrossRefPubMed

18.

Zorzon M, Antonutti L, Masè G, Biasutti E, Vitrani B, Cazzato G (1995) Transient global amnesia and transient ischemic attack. Natural history, vascular risk factors, and associated conditions. Stroke 26(9):1536–1542. https://doi.org/10.1161/01.str.26.9.1536CrossRefPubMed

19.

Cejas C, Cisneros LF, Lagos R et al (2010) Internal jugular vein valve incompetence is highly prevalent in transient global amnesia. Stroke 41:67–71CrossRef

20.

Altamura C, Vernieri F (2010) Internal jugular vein valve incompetence in transient global amnesia. More circumstantial evidence or the proof solving the mystery? Stroke 41:1–2CrossRef

21.

Modabbernia A, Taslimi S, Ashrafi M, Modabbernia MJ, Hu HH (2012) Internal jugular vein reflux in patients with transient global amnesia: a meta-analysis of case-control studies. Acta Neurol Belg 112(3):237–244. https://doi.org/10.1007/s13760-012-0072-7CrossRefPubMed

22.

Agosti C, Borroni B, Akkawi NM, Padovani A (2010) Cerebrovascular risk factors and triggers in transient global amnesia patients with and without jugular valve incompetence: results from a sample of 243 patients. Eur Neurol 63(5):291–294. https://doi.org/10.1159/000292502CrossRefPubMed

23.

Olesen J, Jørgensen MB (1986) Leao’s spreading depression in the hippocampus explains transient global amnesia. A hypothesis Acta Neurol Scand 73(2):219–220CrossRef

24.

Quinette P, Guillery-Girard B, Dayan J et al (2006) What does transient global amnesia really mean? Review of the literature and thorough study of 142 cases. Brain 129(Pt 7):1640–1658. https://doi.org/10.1093/brain/awl105CrossRefPubMed

25.

Magalhães JE, Sampaio Rocha-Filho PA (2018) Migraine and cerebrovascular diseases: epidemiology, pathophysiological, and clinical considerations. Headache 58(8):1277–1286. https://doi.org/10.1111/head.13378CrossRefPubMed

26.

Stroup DF, Berlin JA, Morton SC, Olkin I, Williamson GD, Rennie D, Moher D, Becker BJ, Sipe TA, Thacker SB (2000) Meta-analysis of observational studies in epidemiology: a proposal for reporting. Meta-analysis of observational studies in epidemiology (MOOSE) group. JAMA 283(15):2008–2012. https://doi.org/10.1001/jama.283.15.2008 (PMID: 10789670)CrossRef

27.

Caplan L (1985) Transient global amnesia. In: Vinken PJ, Gruyn GW, Klawans HL (eds) Handbook of Clinical Neurology, Vol 1(45). Elsevier, The Netherlands, pp 205–218

28.

Liampas I, Siokas V, Brotis A, Aloizou AM, Mentis AA, Vikelis M, Dardiotis E (2020) Meta-analysis of melatonin levels in cluster headache-review of clinical implications. Acta Neurol Scand. 142(4):356–367. https://doi.org/10.1111/ane.13317 (Epub ahead of print. PMID: 32677039)CrossRefPubMed

29.

Review Manager (RevMan) [Computer program]. Version 5.4. Copenhagen: The Nordic cochrane centre, The cochrane collaboration, build date 26/05/2020

30.

Yi M, Sherzai AZ, Ani C et al (2019) Strong association between migraine and transient global amnesia: a National inpatient sample analysis. J Neuropsychiatry Clin Neurosci 31(1):43–48. https://doi.org/10.1176/appi.neuropsych.17120353CrossRefPubMed

31.

Jovanovic ZB, Pavlovic AM, Vujisic Tesic BP et al (2018) Comprehensive ultrasound assessment of the craniocervical circulation in transient global amnesia. J Ultrasound Med 37(2):479–486. https://doi.org/10.1002/jum.14355CrossRefPubMed

32.

Lin KH, Chen YT, Fuh JL et al (2014) Migraine is associated with a higher risk of transient global amnesia: a nationwide cohort study. Eur J Neurol 21(5):718–724CrossRef

33.

Baracchini C, Farina F, Ballotta E, Meneghetti G, Manara R (2015) No signs of intracranial arterial vasoconstriction in transient global amnesia. J Neuroimaging 25(1):92–96. https://doi.org/10.1111/jon.12090CrossRefPubMed

34.

Maalikjy Akkawi N, Agosti C, Anzola GP et al (2003) Transient global amnesia: a clinical and sonographic study. Eur Neurol 49(2):67–71. https://doi.org/10.1159/000068501CrossRefPubMed

35.

Sander D, Winbeck K, Etgen T, Knapp R, Klingelhöfer J, Conrad B (2000) Disturbance of venous flow patterns in patients with transient global amnesia. Lancet 356(9246):1982–1984. https://doi.org/10.1016/S0140-6736(00)03313-4CrossRefPubMed

36.

Schmidtke K, Ehmsen L (1998) Transient global amnesia and migraine. A case control study. Eur Neurol 40(1):9–14. https://doi.org/10.1159/000007948CrossRefPubMed

37.

Melo TP, Ferro JM, Ferro H (1992) Transient global amnesia. A case control study. Brain 115(Pt 1):261–270. https://doi.org/10.1093/brain/115.1.261CrossRefPubMed

38.

GBD 2016 Headache Collaborators (2018) Global, regional, and national burden of migraine and tension-type headache, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet Neurol 17(11):954–976. https://doi.org/10.1016/S1474-4422(18)30322-3CrossRef

39.

Mahmoud AN, Mentias A, Elgendy AY et al (2018) Migraine and the risk of cardiovascular and cerebrovascular events: a meta-analysis of 16 cohort studies including 1 152 407 subjects. BMJ Open 8(3):e020498. https://doi.org/10.1136/bmjopen-2017-020498 (Published 2018 Mar 27)CrossRefPubMedPubMedCentral

40.

Sacco S, Ornello R, Ripa P et al (2015) Migraine and risk of ischaemic heart disease: a systematic review and meta-analysis of observational studies. Eur J Neurol 22(6):1001–1011. https://doi.org/10.1111/ene.12701CrossRefPubMed

41.

Alessandro L, Calandri IL, Suarez MF et al (2019) Transient global amnesia: clinical features and prognostic factors suggesting recurrence. Arq Neuropsiquiatr 77(1):3–9. https://doi.org/10.1590/0004-282X20180157CrossRefPubMed

42.

Oliveira R, Teodoro T, Marques IB (2020). Risk factors predicting recurrence of transient global amnesia. Neurol Sci. doi: https://doi.org/10.1007/s10072-020-04788-6. Epub ahead of print. PMID: 33033897.

43.

Tynas R, Panegyres PK (2020) Factors determining recurrence in transient global amnesia. BMC Neurol 20(1):83. https://doi.org/10.1186/s12883-020-01658-8 (Published 2020 Mar 6)CrossRefPubMedPubMedCentral

44.

Owen D, Paranandi B, Sivakumar R, Seevaratnam M (2007) Classical diseases revisited: transient global amnesia. Postgrad Med J 83(978):236–239CrossRef

45.

Goadsby PJ (2007) Cortical spreading depression—better understanding and more questions. Focus on “distinct vascular conduction with cortical spreading depression.” J Neurophysiol 97:3827CrossRef

46.

Charles AC, Baca SM (2013) Cortical spreading depression and migraine. Nat Rev Neurol 9:637–644CrossRef

47.

Woods RP, Iacoboni M, Mazziotta JC (1994) Brief report: Bilateral spreading cerebral hypoperfusion during spontaneous migraine headache. N Engl J Med 331:1689–1692CrossRef

48.

Gelmers HJ (1982) Common migraine attacks preceded by focal hyperemia and parietal oligemia in the rCBF pattern. Cephalalgia 2:29–32CrossRef

49.

Liampas IN, Siokas V, Aloizou AM et al (2020) Pyridoxine, folate and cobalamin for migraine: A systematic review. Acta Neurol Scand 142(2):108–120. https://doi.org/10.1111/ane.13251CrossRefPubMed

50.

Liampas I, Siokas V, Mentis AA et al (2020) Serum homocysteine, pyridoxine, folate, and vitamin B12 levels in migraine: systematic review and meta-analysis. Headache 60(8):1508–1534. https://doi.org/10.1111/head.13892 ([published online ahead of print, 2020 Jul 2])CrossRefPubMed

51.

Donnet A (2015) Transient global amnesia triggered by migraine in a French Tertiary-care center: an 11-year retrospective analysis. Headache 55(6):853–859. https://doi.org/10.1111/head.12545CrossRefPubMed

52.

Gross EC, Lisicki M, Fischer D, Sándor PS, Schoenen J (2019) The metabolic face of migraine - from pathophysiology to treatment. Nat Rev Neurol 15(11):627–643. https://doi.org/10.1038/s41582-019-0255-4CrossRefPubMed

53.

Liampas I, Siokas V, Brotis A, Dardiotis E. Vitamin D serum levels in patients with migraine: A meta-analysis [published online ahead of print, 2020 Mar 30]. Rev Neurol (Paris). 2020;S0035–3787(20)30464–1. doi:https://doi.org/10.1016/j.neurol.2019.12.008

54.

Liampas I, Siokas V, Brotis A, Vikelis M, Dardiotis E (2020) Endogenous melatonin levels and therapeutic use of exogenous melatonin in migraine: systematic review and meta-analysis. Headache 60(7):1273–1299. https://doi.org/10.1111/head.13828 ([published online ahead of print, 2020 Apr 30])CrossRefPubMed

55.

Wang X, Michaelis EK (2010) Selective neuronal vulnerability to oxidative stress in the brain. Front Aging Neurosci 30(2):12. https://doi.org/10.3389/fnagi.2010.00012 (PMID: 20552050; PMCID: PMC2874397)CrossRef

56.

Wang X, Pal R, Chen XW et al (2005) High intrinsic oxidative stress may underlie selective vulnerability of the hippocampal CA1 region. Brain Res Mol Brain Res 140:120–126. https://doi.org/10.1016/j.molbrainres.2005.07.018CrossRefPubMed

57.

Bartsch T, Döhring J, Reuter S, Finke C, Rohr A, Brauer H, Deuschl G, Jansen O (2015) Selective neuronal vulnerability of human hippocampal CA1 neurons: lesion evolution, temporal course, and pattern of hippocampal damage in diffusion-weighted MR imaging. J Cereb Blood Flow Metab 35(11):1836–1845. https://doi.org/10.1038/jcbfm.2015.137CrossRefPubMedPubMedCentral

58.

Noël A, Quinette P, Guillery-Girard B et al (2008) Psychopathological factors, memory disorders and transient global amnesia. Br J Psychiatry 193:145–151CrossRef

59.

Peres MFP, Mercante JPP, Tobo PR, Kamei H, Bigal ME (2017) Anxiety and depression symptoms and migraine: a symptom-based approach research. J Headache Pain 18:37CrossRef

60.

Spiegel DR, Smith J, Wade RR, Cherukuru N, Ursani A, Dobruskina Y, Crist T, Busch RF, Dhanani RM, Dreyer N (2017) Transient global amnesia: current perspectives. Neuropsychiatr Dis Treat 24(13):2691–2703. https://doi.org/10.2147/NDT.S130710.PMID:29123402;PMCID:PMC5661450CrossRef

61.

Vongvaivanich K, Lertakyamanee P, Silberstein SD, Dodick DW (2015) Late-life migraine accompaniments: a narrative review. Cephalalgia 35(10):894–911. https://doi.org/10.1177/0333102414560635 (Epub 2014 Dec 12 PMID: 25505036)CrossRefPubMed

62.

Wijman CA, Wolf PA, Kase CS, Kelly-Hayes M, Beiser AS (1998) Migrainous visual accompaniments are not rare in late life: the Framingham study. Stroke 29(8):1539–1543. https://doi.org/10.1161/01.str.29.8.1539 (PMID: 9707189)CrossRefPubMed

63.

Donnet A, Daniel C, Milandre L, Berbis J, Auquier P (2012) Migraine with aura in patients over 50 years of age: the Marseille’s registry. J Neurol 259(9):1868–1873. https://doi.org/10.1007/s00415-012-6423-8 (PMID: 22302276)CrossRefPubMed

64.

Gupta M, Kantor MA, Tung CE, Zhang N, Albers GW (2015) Transient global amnesia associated with a unilateral infarction of the fornix: case report and review of the literature. Front Neurol. 5:291. https://doi.org/10.3389/fneur.2014.00291 (Published 2015 Jan 12)CrossRefPubMedPubMedCentral

65.

Naldi F, Baiardi S, Guarino M, Spinardi L, Cirignotta F, Stracciari A (2017) Posterior hippocampal stroke presenting with transient global amnesia. Neurocase 23(1):22–25. https://doi.org/10.1080/13554794.2016.1270329CrossRefPubMed

66.

Förster A, Al-Zghloul M, Wenz H, Böhme J, Groden C, Neumaier-Probst E (2017) Isolated punctuate hippocampal infarction and transient global amnesia are indistinguishable by means of MRI. Int J Stroke 12(3):292–296. https://doi.org/10.1177/1747493016676613CrossRefPubMed

67.

Liampas I, Chlinos A, Siokas V, Brotis A, Dardiotis E (2019) Assessment of the reporting quality of RCTs for novel oral anticoagulants in venous thromboembolic disease based on the CONSORT statement. J Thromb Thrombolysis 48(4):542–553. https://doi.org/10.1007/s11239-019-01931-9CrossRefPubMed

68.

Kodounis M, Liampas IN, Constantinidis TS et al (2020) Assessment of the reporting quality of double-blind RCTs for ischemic stroke based on the CONSORT statement. J Neurol Sci 415:116938. https://doi.org/10.1016/j.jns.2020.116938CrossRefPubMed

Titel: Migraine in transient global amnesia: a meta-analysis of observational studies
verfasst von: Ioannis Liampas
Athanasios S. Siouras
Vasileios Siokas
Zisis Tsouris
Dimitrios Rikos
Alexandros Brotis
Athina-Maria Aloizou
Metaxia Dastamani
Efthimios Dardiotis
Publikationsdatum: 02.01.2021
Verlag: Springer Berlin Heidelberg
Erschienen in: Journal of Neurology / Ausgabe 1/2022
Print ISSN: 0340-5354
Elektronische ISSN: 1432-1459
DOI: https://doi.org/10.1007/s00415-020-10363-y

Leitlinien kompakt für die Neurologie

Mit medbee Pocketcards sicher entscheiden.

^{Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag}

Kostenlos registrieren

Neu im Fachgebiet Neurologie

Hirnblutung unter DOAK und VKA ähnlich bedrohlich

17.05.2024 Direkte orale Antikoagulanzien Nachrichten

Kommt es zu einer nichttraumatischen Hirnblutung, spielt es keine große Rolle, ob die Betroffenen zuvor direkt wirksame orale Antikoagulanzien oder Marcumar bekommen haben: Die Prognose ist ähnlich schlecht.

Thrombektomie auch bei großen Infarkten von Vorteil

16.05.2024 Ischämischer Schlaganfall Nachrichten

Auch ein sehr ausgedehnter ischämischer Schlaganfall scheint an sich kein Grund zu sein, von einer mechanischen Thrombektomie abzusehen. Dafür spricht die LASTE-Studie, an der Patienten und Patientinnen mit einem ASPECTS von maximal 5 beteiligt waren.

Schwindelursache: Massagepistole lässt Otholiten tanzen

14.05.2024 Benigner Lagerungsschwindel Nachrichten

Wenn jüngere Menschen über ständig rezidivierenden Lagerungsschwindel klagen, könnte eine Massagepistole der Auslöser sein. In JAMA Otolaryngology warnt ein Team vor der Anwendung hochpotenter Geräte im Bereich des Nackens.

Schützt Olivenöl vor dem Tod durch Demenz?

10.05.2024 Morbus Alzheimer Nachrichten

Konsumieren Menschen täglich 7 Gramm Olivenöl, ist ihr Risiko, an einer Demenz zu sterben, um mehr als ein Viertel reduziert – und dies weitgehend unabhängig von ihrer sonstigen Ernährung. Dafür sprechen Auswertungen zweier großer US-Studien.

Update Neurologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

Newsletter bestellen

Die Highlights vom Kongress des American College of Cardiology 2024

Springer Medizin

Abstract

Background

Purpose

Methodology

Results

Conclusions

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 1/2022

Acute bilateral optic/chiasm neuritis with longitudinal extensive transverse myelitis in longstanding stable multiple sclerosis following vector-based vaccination against the SARS-CoV-2

Correction to: Long-term effects of bilateral pallidal deep brain stimulation in dystonia: a follow-up between 8 and 16 years

Chronobiology of transient global amnesia

Long COVID: cognitive complaints (brain fog) and dysfunction of the cingulate cortex

Capturing vertigo in the emergency room: three tools to double the rate of diagnosis