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31.05.2022

A Systematic Review and Meta-analysis of Parental Depression, Antidepressant Usage, Antisocial Personality Disorder, and Stress and Anxiety as Risk Factors for Attention-Deficit/Hyperactivity Disorder (ADHD) in Children

verfasst von: Lara R. Robinson, Rebecca H. Bitsko, Brenna O’Masta, Joseph R. Holbrook, Jean Ko, Caroline M. Barry, Brion Maher, Audrey Cerles, Kayla Saadeh, Laurel MacMillan, Zayan Mahmooth, Jeanette Bloomfield, Margaret Rush, Jennifer W. Kaminski

Erschienen in: Prevention Science

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Abstract

Poor parental mental health and stress have been associated with children’s mental disorders, including attention-deficit/hyperactivity disorder (ADHD), through social, genetic, and neurobiological pathways. To determine the strength of the associations between parental mental health and child ADHD, we conducted a set of meta-analyses to examine the association of parent mental health indicators (e.g., parental depression, antidepressant usage, antisocial personality disorder, and stress and anxiety) with subsequent ADHD outcomes in children. Eligible ADHD outcomes included diagnosis or symptoms. Fifty-eight articles published from 1980 to 2019 were included. We calculated pooled effect sizes, accounting for each study’s conditional variance, separately for test statistics based on ADHD as a dichotomous (e.g., diagnosis or clinical cutoffs) or continuous measurement (e.g., symptoms of ADHD subtypes of inattentiveness and hyperactivity/impulsivity). Parental stress and parental depression were significantly associated with increased risk for ADHD overall and both symptoms and diagnosis. Specifically, maternal stress and anxiety, maternal prenatal stress, maternal depression, maternal post-partum depression, and paternal depression were positively associated with ADHD. In addition, parental depression was associated with symptoms of ADHD inattentive and hyperactive/impulsive subtypes. Parental antisocial personality disorder was also positively associated with ADHD overall and specifically ADHD diagnosis. Prenatal antidepressant usage was associated with ADHD when measured dichotomously only. These findings raise the possibility that prevention strategies promoting parental mental health and addressing parental stress could have the potential for positive long-term impacts on child health, well-being, and behavioral outcomes.

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Titel: A Systematic Review and Meta-analysis of Parental Depression, Antidepressant Usage, Antisocial Personality Disorder, and Stress and Anxiety as Risk Factors for Attention-Deficit/Hyperactivity Disorder (ADHD) in Children
verfasst von: Lara R. Robinson
Rebecca H. Bitsko
Brenna O’Masta
Joseph R. Holbrook
Jean Ko
Caroline M. Barry
Brion Maher
Audrey Cerles
Kayla Saadeh
Laurel MacMillan
Zayan Mahmooth
Jeanette Bloomfield
Margaret Rush
Jennifer W. Kaminski
Publikationsdatum: 31.05.2022
Verlag: Springer US
Erschienen in: Prevention Science
Print ISSN: 1389-4986
Elektronische ISSN: 1573-6695
DOI: https://doi.org/10.1007/s11121-022-01383-3

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A Systematic Review and Meta-analysis of Parental Depression, Antidepressant Usage, Antisocial Personality Disorder, and Stress and Anxiety as Risk Factors for Attention-Deficit/Hyperactivity Disorder (ADHD) in Children

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Live-Webinar "Urologie und Sexualmedizin in der Praxis"

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