nach oben

Clinical Rheumatology

Erschienen in:

01.11.2013 | Original Article

A meta-analysis of alcohol consumption and the risk of gout

verfasst von: Meiyun Wang, Xiubo Jiang, Wenlong Wu, Dongfeng Zhang

Erschienen in: Clinical Rheumatology | Ausgabe 11/2013

Einloggen, um Zugang zu erhalten

Abstract

Alcohol consumption had been linked to the risk of gout theoretically, but the results from observational studies were conflicting. Hence, a meta-analysis was conducted to assess the effect of alcohol consumption on the risk of gout. A comprehensive search was performed to identify all eligible studies on the association of alcohol consumption with gout risk. Pooled relative risks (RRs) with 95 % confidence intervals (CIs) from fixed and random effects models were calculated. A total of 12 articles with 17 studies involving 42,924 cases met the inclusion criteria. The pooled RR for highest vs. non/occasional alcohol drinking in every study was 1.98 (95 % CI, 1.52–2.58). The RRs for light (≤1 drink/day), moderate (>1 to <3 drinks/day), and heavy drinking (≥3 drinks/day) vs. non/occasional alcohol drinking were 1.16 (95 % CI, 1.07–1.25), 1.58 (95 % CI, 1.50–1.66), and 2.64 (95 % CI, 2.26–3.09), respectively. The results suggested that alcohol consumption might be associated with increased risk of gout.

Terkeltaub RA (2003) Clinical practice. Gout N Engl J Med 349(17):1647–55. doi:10.1056/NEJMcp030733 CrossRef

Saag KG, Mikuls TR (2005) Recent advances in the epidemiology of gout. Curr Rheumatol Rep 7(3):235–41PubMedCrossRef

Luk AJ, Simkin PA (2005) Epidemiology of hyperuricemia and gout. Am J Manag Care 11(15 Suppl):S435–S442, quiz S465-8PubMed

Arromdee E, Michet CJ, Crowson CS, O'Fallon WM, Gabriel SE (2002) Epidemiology of gout: is the incidence rising? J Rheumatol 29(11):2403–6PubMed

Mikuls TR, Farrar JT, Bilker WB, Fernandes S, Schumacher HR Jr, Saag KG (2005) Gout epidemiology: results from the UK General Practice Research Database, 1990–1999. Ann Rheum Dis 64(2):267–72. doi:10.1136/ard.2004.024091 PubMedCrossRef

Lawrence RC, Felson DT, Helmick CG, Arnold LM, Choi H, Deyo RA, Gabriel S, Hirsch R, Hochberg MC, Hunder GG, Jordan JM, Katz JN, Kremers HM, Wolfe F, National Arthritis Data W (2008) Estimates of the prevalence of arthritis and other rheumatic conditions in the United States. Part II Arthritis Rheum 58(1):26–35. doi:10.1002/art.23176 CrossRef

Annemans L, Spaepen E, Gaskin M, Bonnemaire M, Malier V, Gilbert T, Nuki G (2008) Gout in the UK and Germany: prevalence, comorbidities and management in general practice 2000–2005. Ann Rheum Dis 67(7):960–6. doi:10.1136/ard.2007.076232 PubMedCrossRef

Yoo HG, Lee SI, Chae HJ, Park SJ, Lee YC, Yoo WH (2011) Prevalence of insulin resistance and metabolic syndrome in patients with gouty arthritis. Rheumatol Int 31(4):485–91. doi:10.1007/s00296-009-1304-x PubMedCrossRef

Choi HK (2010) A prescription for lifestyle change in patients with hyperuricemia and gout. Curr Opin Rheumatol 22(2):165–72. doi:10.1097/BOR.0b013e328335ef38 PubMedCrossRef

10.

Novak S, Melkonian AK, Patel PA, Kleinman NL, Joseph-Ridge N, Brook RA (2007) Metabolic syndrome-related conditions among people with and without gout: prevalence and resource use. Curr Med Res Opin 23(3):623–30. doi:10.1185/030079906X167651 PubMedCrossRef

11.

Gaffo AL, Edwards NL, Saag KG (2009) Gout. Hyperuricemia and cardiovascular disease: how strong is the evidence for a causal link? Arthritis Res Ther 11(4):240PubMedCrossRef

12.

Choi HK, Mount DB, Reginato AM (2005) Pathogenesis of gout. Ann Intern Med 143(7):499–516PubMedCrossRef

13.

Di Castelnuovo A, Costanzo S, Bagnardi V, Donati MB, Iacoviello L, de Gaetano G (2006) Alcohol dosing and total mortality in men and women: an updated meta-analysis of 34 prospective studies. Arch Intern Med 166(22):2437–45. doi:10.1001/archinte.166.22.2437 PubMedCrossRef

14.

Choi HK, Atkinson K, Karlson EW, Willett W, Curhan G (2004) Alcohol intake and risk of incident gout in men: a prospective study. Lancet 363(9417):1277–81. doi:10.1016/S0140-6736(04)16000-5 PubMedCrossRef

15.

Cea Soriano L, Rothenbacher D, Choi HK, Garcia Rodriguez LA (2011) Contemporary epidemiology of gout in the UK general population. Arthritis Res Ther 13(2):R39. doi:10.1186/ar3272 PubMedCrossRef

16.

Lyu LC, Hsu CY, Yeh CY, Lee MS, Huang SH, Chen CL (2003) A case–control study of the association of diet and obesity with gout in Taiwan. Am J Clin Nutr 78(4):690–701PubMed

17.

Lee CH, Sung NY, Lee J, Bae SC (2013) Factors associated with gout in South Koreans: analysis using the National Health Insurance Corporation and the National Health Screening Exam databases. Clin Rheumatol. doi:10.1007/s10067-013-2183-9

18.

Williams PT (2008) Effects of diet, physical activity and performance, and body weight on incident gout in ostensibly healthy, vigorously active men. Am J Clin Nutr 87(5):1480–7PubMed

19.

Cohen SD, Kimmel PL, Neff R, Agodoa L, Abbott KC (2008) Association of incident gout and mortality in dialysis patients. J Am Soc Nephrol 19(11):2204–10. doi:10.1681/ASN.2007111256 PubMedCrossRef

20.

Cheng XY, Miao ZM, Liu L, Han L, Li CG (2012) Relationship between gouty arthritis and dietary habits of residents in Qingdao. Acta Academiae Medicinae Qingdao Universitatis 48(2):95–97

21.

Jin M, Cai S, Guo J, Zhu Y, Li M, Yu Y, Zhang S, Chen K (2012) Alcohol drinking and all cancer mortality: a meta-analysis. Ann Oncol 24(3):807–16. doi:10.1093/ann onc/mds508 PubMedCrossRef

22.

Berlin JA, Longnecker MP, Greenland S (1993) Meta-analysis of epidemiologic dose–response data. Epidemiology 4(3):218–28PubMedCrossRef

23.

Rota M, Pasquali E, Scotti L, Pelucchi C, Tramacere I, Islami F, Negri E, Boffetta P, Bellocco R, Corrao G, La Vecchia C, Bagnardi V (2012) Alcohol drinking and epithelial ovarian cancer risk. a systematic review and meta-analysis. Gynecol Oncol 125(3):758–63. doi:10.1016/j.ygyno.2012.03.031 PubMedCrossRef

24.

Higgins JP, Thompson SG (2002) Quantifying heterogeneity in a meta-analysis. Stat Med 21(11):1539–58. doi:10.1002/sim.1186 PubMedCrossRef

25.

Higgins JP, Thompson SG, Deeks JJ, Altman DG (2003) Measuring inconsistency in meta-analyses. BMJ 327(7414):557–60. doi:10.1136/bmj.327.7414.557 PubMedCrossRef

26.

Tobias A (1999) Assessing the influence of a single study in the meta-analysis estimate. Stata Tech Bull 47:15–17

27.

Egger M, Davey Smith G, Schneider M, Minder C (1997) Bias in meta-analysis detected by a simple, graphical test. BMJ 315(7109):629–34PubMedCrossRef

28.

Chang SJ, Ko YC, Wang TN, Chang FT, Cinkotai FF, Chen CJ (1997) High prevalence of gout and related risk factors in Taiwan's aborigines. J Rheumatol 24(7):1364–9PubMed

29.

Lin KC, Lin HY, Chou P (1999) The interaction between uric acid level and other risk factors on the development of gout among asymptomatic hyperuricemic men in a prospective study. Asymptomatic hyperuricemia 27(6):1501–1505

30.

Bhole V, de Vera M, Rahman MM, Krishnan E, Choi H (2010) Epidemiology of gout in women: fifty-two-year followup of a prospective cohort. Arthritis Rheum 62(4):1069–76. doi:10.1002/art.27338 PubMedCrossRef

31.

Li ZF, Di PT, Liu WC, Xu XF, Peng JY (2012) A case–control study of the risk factors with gout in Yunnan. CJGMCM 27(4):663–665

32.

Wang Y, Yan S, Li C, Zhao S, Lv J, Wang F, Meng D, Han L, Miao Z (2012) Risk factors for gout developed from hyperuricemia in China: a five-year prospective cohort study. Rheumatol Int. doi:10.1007/s00296-012-2439-8

33.

Munafo MR, Flint J (2004) Meta-analysis of genetic association studies. Trends Genet 20(9):439–44. doi:10.1016/j.tig.2004.06.014 PubMedCrossRef

34.

Hamling J, Lee P, Weitkunat R, Ambuhl M (2008) Facilitating meta-analyses by deriving relative effect and precision estimates for alternative comparisons from a set of estimates presented by exposure level or disease category. Stat Med 27(7):954–70. doi:10.1002/sim.3013 PubMedCrossRef

Titel: A meta-analysis of alcohol consumption and the risk of gout
verfasst von: Meiyun Wang
Xiubo Jiang
Wenlong Wu
Dongfeng Zhang
Publikationsdatum: 01.11.2013
Verlag: Springer London
Erschienen in: Clinical Rheumatology / Ausgabe 11/2013
Print ISSN: 0770-3198
Elektronische ISSN: 1434-9949
DOI: https://doi.org/10.1007/s10067-013-2319-y

Leitlinien kompakt für die Innere Medizin

Mit medbee Pocketcards sicher entscheiden.

^{Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag}

Kostenlos registrieren

Neu im Fachgebiet Innere Medizin

Mehr Lebenszeit mit Abemaciclib bei fortgeschrittenem Brustkrebs?

24.05.2024 Mammakarzinom Nachrichten

In der MONARCHE-3-Studie lebten Frauen mit fortgeschrittenem Hormonrezeptor-positivem, HER2-negativem Brustkrebs länger, wenn sie zusätzlich zu einem nicht steroidalen Aromatasehemmer mit Abemaciclib behandelt wurden; allerdings verfehlte der numerische Zugewinn die statistische Signifikanz.

ADT zur Radiatio nach Prostatektomie: Wenn, dann wohl länger

24.05.2024 Prostatakarzinom Nachrichten

Welchen Nutzen es trägt, wenn die Strahlentherapie nach radikaler Prostatektomie um eine Androgendeprivation ergänzt wird, hat die RADICALS-HD-Studie untersucht. Nun liegen die Ergebnisse vor. Sie sprechen für länger dauernden Hormonentzug.

„Überwältigende“ Evidenz für Tripeltherapie beim metastasierten Prostata-Ca.

22.05.2024 Prostatakarzinom Nachrichten

Patienten mit metastasiertem hormonsensitivem Prostatakarzinom sollten nicht mehr mit einer alleinigen Androgendeprivationstherapie (ADT) behandelt werden, mahnt ein US-Team nach Sichtung der aktuellen Datenlage. Mit einer Tripeltherapie haben die Betroffenen offenbar die besten Überlebenschancen.

So sicher sind Tattoos: Neue Daten zur Risikobewertung

22.05.2024 Melanom Nachrichten

Das größte medizinische Problem bei Tattoos bleiben allergische Reaktionen. Melanome werden dadurch offensichtlich nicht gefördert, die Farbpigmente könnten aber andere Tumoren begünstigen.

Update Innere Medizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

Newsletter bestellen

Die Highlights vom Kongress des American College of Cardiology 2024

Springer Medizin

Abstract

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 11/2013

Does enthesopathy relate to M694V gene mutation in patients with Familial Mediterranean fever?

Gout: from international guidelines to current practice. Results from a physician questionnaire

Focal Raynaud’s phenomenon of the 5th digit related to iPad reading posture

Questionnaire survey evaluating disease-related knowledge for 149 primary gout patients and 184 doctors in South China

Relapsing polychondritis: a review