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Erschienen in: Clinical Oral Investigations 7/2016

18.11.2015 | Original Article

Epulis: a study of 92 cases with special emphasis on histopathological diagnosis and associated clinical data

verfasst von: Astrid Truschnegg, Stephan Acham, Birgit Alexandra Kiefer, Norbert Jakse, Alfred Beham

Erschienen in: Clinical Oral Investigations | Ausgabe 7/2016

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Abstract

Objectives

Aim of the present study was clinical and histopathological evaluation of a series of epulides to provide clinicians data to frequency distribution and biological behaviour of different underlying entities.

Materials and methods

Ninety-two cases of epulides removed by CO2-laser at the Department of Oral Surgery and Radiology, Medical University of Graz from 2000 to 2014 were studied retrospectively for clinical data and histopathological diagnosis.

Results

In the presented study, histopathological examination revealed peripheral ossifying fibroma (32.6 %), fibroma/fibrosis (29.3 %), giant cell lesion (13.1 %) and granuloma pyogenicum (8.7 %) as the most frequent underlying entities. For the first time, hyperplastic squamous epithelium (7.6 %), granulation tissue (5.4 %) and peripheral odontogenic fibromas (3.3 %) were detected to clinically appear as epulides. Irrespective of the histological diagnosis, the mean age in our patients was 43.8 years. The majority of the lesions were found in the frontal region of both jaws. In all cases, the patients showed poor oral hygiene, local gingivitis and some of them an occlusal trauma.

Conclusions

To identify different entities with different biological behaviour, to exclude malignant tumours and to identify new entities among epulides, histopathological examination is required. Poor oral hygiene and occlusal trauma seem to play an important role in the pathogenesis and could be risk factors for recurrences.

Clinical relevance

Frequency distribution of different entities in epulides is provided to clinicians, and new histopathological entities were detected to clinically appear as epulides.
Literatur
1.
Zurück zum Zitat Kfir Y, Buchner A, Hansen LS (1980) Reactive lesions of the gingiva. A clinicopathological study of 741 cases. J Periodontol 51(11):655–661CrossRefPubMed Kfir Y, Buchner A, Hansen LS (1980) Reactive lesions of the gingiva. A clinicopathological study of 741 cases. J Periodontol 51(11):655–661CrossRefPubMed
2.
Zurück zum Zitat Zain RB, Fei YJ (1990) Fibrous lesions of the gingiva: a histopathologic analysis of 204 cases. Oral Surg Oral Med Oral Pathol 70(4):466–470CrossRefPubMed Zain RB, Fei YJ (1990) Fibrous lesions of the gingiva: a histopathologic analysis of 204 cases. Oral Surg Oral Med Oral Pathol 70(4):466–470CrossRefPubMed
3.
Zurück zum Zitat Chaparro-Avendano AV, Berini-Aytes L, Gay Escoda C (2005) Peripheral giant cell granuloma. A report of five cases and review of the literature. Med Oral Patol Oral Cir Bucal 10(1):48–57 Chaparro-Avendano AV, Berini-Aytes L, Gay Escoda C (2005) Peripheral giant cell granuloma. A report of five cases and review of the literature. Med Oral Patol Oral Cir Bucal 10(1):48–57
4.
Zurück zum Zitat Benkert P, Passler L, Steidl R (1982) Die Epuliden – klinische und histologische Untersuchungen anhand von 208 Fällen. Stomatol DDR 32:426–431PubMed Benkert P, Passler L, Steidl R (1982) Die Epuliden – klinische und histologische Untersuchungen anhand von 208 Fällen. Stomatol DDR 32:426–431PubMed
5.
Zurück zum Zitat Anneroth G, Sigurdson A (1983) Hyperplastic lesions of the gingiva and alveolar mucosa. A study of 175 cases. Acta Odontol Scand 41(2):75–86CrossRefPubMed Anneroth G, Sigurdson A (1983) Hyperplastic lesions of the gingiva and alveolar mucosa. A study of 175 cases. Acta Odontol Scand 41(2):75–86CrossRefPubMed
6.
Zurück zum Zitat Katsikeris N, Kakarantza-Angelopoulou E, Angelopoulos AP (1988) Peripheral giant cell granuloma. Clinicopathologic study of 224 new cases and review of 956 reported cases. Int J Oral Maxillofac Surg 17(2):94–99CrossRefPubMed Katsikeris N, Kakarantza-Angelopoulou E, Angelopoulos AP (1988) Peripheral giant cell granuloma. Clinicopathologic study of 224 new cases and review of 956 reported cases. Int J Oral Maxillofac Surg 17(2):94–99CrossRefPubMed
7.
Zurück zum Zitat Buchner A, Calderon S, Ramon Y (1977) Localized hyperplastic lesions of the gingiva: a clinicopathological study of 302 lesions. J Periodontol 48(2):101–104CrossRefPubMed Buchner A, Calderon S, Ramon Y (1977) Localized hyperplastic lesions of the gingiva: a clinicopathological study of 302 lesions. J Periodontol 48(2):101–104CrossRefPubMed
8.
Zurück zum Zitat Macleod RI, Soames JV (1987) Epulides: a clinicopathological study of a series of 200 consecutive lesions. Br Dent J 163(2):51–53CrossRefPubMed Macleod RI, Soames JV (1987) Epulides: a clinicopathological study of a series of 200 consecutive lesions. Br Dent J 163(2):51–53CrossRefPubMed
9.
Zurück zum Zitat International Statistical Classification of Diseases and Related Health Problems 10th Revision (2015) ICD-10 WHO Version k 06.8 International Statistical Classification of Diseases and Related Health Problems 10th Revision (2015) ICD-10 WHO Version k 06.8
10.
Zurück zum Zitat Tamarit-Borrás M, Delgado-Molina E, Berini-Aytés L, Gay-Escoda C (2005) Removal of hyperplastic lesions of the oral cavity. A retrospective study of 128 cases. Med Oral Patol Cir Bucal 10(2):151–162 Tamarit-Borrás M, Delgado-Molina E, Berini-Aytés L, Gay-Escoda C (2005) Removal of hyperplastic lesions of the oral cavity. A retrospective study of 128 cases. Med Oral Patol Cir Bucal 10(2):151–162
11.
Zurück zum Zitat Buchner A, Shnaiderman-Shapiro A, Vered M (2010) Relative frequency of localized reactive hyperplastic lesions of the gingiva: a retrospective study of 1675 cases from Israel. J Oral Pathol Med 39(8):631–638CrossRefPubMed Buchner A, Shnaiderman-Shapiro A, Vered M (2010) Relative frequency of localized reactive hyperplastic lesions of the gingiva: a retrospective study of 1675 cases from Israel. J Oral Pathol Med 39(8):631–638CrossRefPubMed
12.
Zurück zum Zitat Effiom OA, Adeyemo WL, Soyele OO (2011) Focal reactive lesions of the gingiva: an analysis of 314 cases at a tertiary health institution in Nigeria. Niger Med J 52(1):35–40PubMedPubMedCentral Effiom OA, Adeyemo WL, Soyele OO (2011) Focal reactive lesions of the gingiva: an analysis of 314 cases at a tertiary health institution in Nigeria. Niger Med J 52(1):35–40PubMedPubMedCentral
13.
Zurück zum Zitat Naderi NJ, Eshghyar N, Esfehanian H (2012) Reactive lesions of the oral cavitiy: a retrospective study on 2068 cases. Dent Res J 9(3):251–255 Naderi NJ, Eshghyar N, Esfehanian H (2012) Reactive lesions of the oral cavitiy: a retrospective study on 2068 cases. Dent Res J 9(3):251–255
14.
Zurück zum Zitat Kashyap B, Reddy PS, Nalini P (2012) Reactive lesions of oral cavitiy. A survey of 100 cases in Eluru. West Godavari District 3(3):294–297 Kashyap B, Reddy PS, Nalini P (2012) Reactive lesions of oral cavitiy. A survey of 100 cases in Eluru. West Godavari District 3(3):294–297
15.
Zurück zum Zitat Zhang W, Chen Y, An Z, Geng N, Bao D (2007) Reactive gingival lesions: a retrospective study of 2.439 cases. Quintessence Int 38(2):103–110PubMed Zhang W, Chen Y, An Z, Geng N, Bao D (2007) Reactive gingival lesions: a retrospective study of 2.439 cases. Quintessence Int 38(2):103–110PubMed
16.
Zurück zum Zitat Lee KW (1968) The fibrous epulis and related lesions. Granuloma pyogenicum, ‘pregnancy tumour’, fibro-epithelial polyp and calcifying fibroblastic granuloma. A clinico-pathological study. Periodontics 6(6):277–292PubMed Lee KW (1968) The fibrous epulis and related lesions. Granuloma pyogenicum, ‘pregnancy tumour’, fibro-epithelial polyp and calcifying fibroblastic granuloma. A clinico-pathological study. Periodontics 6(6):277–292PubMed
17.
18.
Zurück zum Zitat Gaspar L, Szabo G (1991) Removal of epulis by CO2-laser. J Clin Laser Med Surg 9(4):289–294PubMed Gaspar L, Szabo G (1991) Removal of epulis by CO2-laser. J Clin Laser Med Surg 9(4):289–294PubMed
19.
Zurück zum Zitat Gardner DG (1982) The peripheral odontogenic fibroma: an attempt at clarification. Oral Surg Oral Med Oral Pathol 54(1):40–48CrossRefPubMed Gardner DG (1982) The peripheral odontogenic fibroma: an attempt at clarification. Oral Surg Oral Med Oral Pathol 54(1):40–48CrossRefPubMed
20.
Zurück zum Zitat Allerbeck M, Schlegel D, Triadan H (1960) Zum Zusammenhang zwischen Biss- und Parodontalbefunden bei Schwangeren unter besonderer Berücksichtigung hyperplastischer Parodontopathien. DZZ 15:813–817 Allerbeck M, Schlegel D, Triadan H (1960) Zum Zusammenhang zwischen Biss- und Parodontalbefunden bei Schwangeren unter besonderer Berücksichtigung hyperplastischer Parodontopathien. DZZ 15:813–817
21.
Zurück zum Zitat Schoenbauer F (1960) Contribution to the clinical aspects and therapy of epulis. Wien Klin Wochenschr 72:768–769PubMed Schoenbauer F (1960) Contribution to the clinical aspects and therapy of epulis. Wien Klin Wochenschr 72:768–769PubMed
22.
Zurück zum Zitat Mutschelknauss R (1962) Klinisch morphologische Studie zur formalen Genese der Epulis. Stoma 15:170–184 Mutschelknauss R (1962) Klinisch morphologische Studie zur formalen Genese der Epulis. Stoma 15:170–184
23.
Zurück zum Zitat Andrä A (1966) Die Formen der Epulis und ihre Behandlungen in der zahnärztlichen Ambulanz. Zahnärztekalender der DDR 226-236 Andrä A (1966) Die Formen der Epulis und ihre Behandlungen in der zahnärztlichen Ambulanz. Zahnärztekalender der DDR 226-236
24.
Zurück zum Zitat Mergoni G, Meleti M, Magnolo S, Giovannacci I, Corcione L, Vescovi P (2015) Peripheral ossifying fibroma: a clinicopathologic study of 27 cases and review of the literature with emphasis in histomorphologic features. J Indian Soc Periodontol 19(1):83–87CrossRefPubMedPubMedCentral Mergoni G, Meleti M, Magnolo S, Giovannacci I, Corcione L, Vescovi P (2015) Peripheral ossifying fibroma: a clinicopathologic study of 27 cases and review of the literature with emphasis in histomorphologic features. J Indian Soc Periodontol 19(1):83–87CrossRefPubMedPubMedCentral
25.
Zurück zum Zitat García de Marcos JA, García de Marcos MJ, Arroyo Rodriguez S, Chiarri Rodrigo J, Poblet E (2010) Peripheral ossifying fibroma: a clinical and immunohistochemical study of four cases. J Oral Sci 52(1):95–99CrossRefPubMed García de Marcos JA, García de Marcos MJ, Arroyo Rodriguez S, Chiarri Rodrigo J, Poblet E (2010) Peripheral ossifying fibroma: a clinical and immunohistochemical study of four cases. J Oral Sci 52(1):95–99CrossRefPubMed
26.
Zurück zum Zitat Mighell AJ, Robinson PA, Hume WJ (1995) Peripheral giant cell granuloma: a clinical study of 77 cases from 62 patients, and literature review. Oral Dis 1(1):12–19CrossRefPubMed Mighell AJ, Robinson PA, Hume WJ (1995) Peripheral giant cell granuloma: a clinical study of 77 cases from 62 patients, and literature review. Oral Dis 1(1):12–19CrossRefPubMed
27.
Zurück zum Zitat Bodner L, Peist M, Gatot A, Fliss DM (1997) Growth potential of peripheral giant cell granuloma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 83(5):548–551CrossRefPubMed Bodner L, Peist M, Gatot A, Fliss DM (1997) Growth potential of peripheral giant cell granuloma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 83(5):548–551CrossRefPubMed
28.
Zurück zum Zitat Andersen L, Fejerskov O, Philipsen HP (1973) Oral giant cell granulomas. A clinical and histological study of 129 new cases. Acta Pathol Microbiol Scand A 81(5):606–616PubMed Andersen L, Fejerskov O, Philipsen HP (1973) Oral giant cell granulomas. A clinical and histological study of 129 new cases. Acta Pathol Microbiol Scand A 81(5):606–616PubMed
29.
Zurück zum Zitat Gándara-Rey JM, Pacheco Martins Carneiro JL, Gandara-Vila P, Blanco-Carrion A, García-García A, Madriñan-Graña P, Martín MS (2002) Peripheral giant-cell granuloma. Review of 13 cases. Med Oral 7(4):254–259PubMed Gándara-Rey JM, Pacheco Martins Carneiro JL, Gandara-Vila P, Blanco-Carrion A, García-García A, Madriñan-Graña P, Martín MS (2002) Peripheral giant-cell granuloma. Review of 13 cases. Med Oral 7(4):254–259PubMed
30.
Zurück zum Zitat Shadman N, Ebrahimi SF, Jafari S, Eslami M (2009) Peripheral giant cell granuloma: a review of 123 cases. Dent Res J 6(1):47–50 Shadman N, Ebrahimi SF, Jafari S, Eslami M (2009) Peripheral giant cell granuloma: a review of 123 cases. Dent Res J 6(1):47–50
31.
Zurück zum Zitat Vinay G, Mangala Gowri SR, Anbalagan J (2013) Sex determination of human mandible using metrical parameters. J Clin Diagn Res 7(12):2671–2673 Vinay G, Mangala Gowri SR, Anbalagan J (2013) Sex determination of human mandible using metrical parameters. J Clin Diagn Res 7(12):2671–2673
32.
Zurück zum Zitat Al-Khateeb T, Ababneh K (2003) Oral pyogenic granuloma in Jordanians: a retrospective analysis of 108 cases. J Oral Maxillofac Surg 61(11):1285–1288CrossRefPubMed Al-Khateeb T, Ababneh K (2003) Oral pyogenic granuloma in Jordanians: a retrospective analysis of 108 cases. J Oral Maxillofac Surg 61(11):1285–1288CrossRefPubMed
33.
Zurück zum Zitat Zarei MR, Chamani G, Amanpoor S (2007) Reactive hyperplasia of the oral cavity in Kerman province, Iran: a review of 172 cases. Br J Oral Maxillofac Surg 45(4):288–292CrossRefPubMed Zarei MR, Chamani G, Amanpoor S (2007) Reactive hyperplasia of the oral cavity in Kerman province, Iran: a review of 172 cases. Br J Oral Maxillofac Surg 45(4):288–292CrossRefPubMed
34.
Zurück zum Zitat Krishnapillai R, Punnoose K, Angadi PV, Koneru A (2012) Oral pyogenic granulma – a review of 215 cases in South Indian Teaching Hospital, Karnataka, over a period of 20 years. Oral Maxillofac Surg 16(3):305–309 Krishnapillai R, Punnoose K, Angadi PV, Koneru A (2012) Oral pyogenic granulma – a review of 215 cases in South Indian Teaching Hospital, Karnataka, over a period of 20 years. Oral Maxillofac Surg 16(3):305–309
35.
Zurück zum Zitat Saravana GH (2009) Oral pyogenic granuloma: a review of 137 cases. Br J Oral Maxillofac Surg 47(4):318–319CrossRefPubMed Saravana GH (2009) Oral pyogenic granuloma: a review of 137 cases. Br J Oral Maxillofac Surg 47(4):318–319CrossRefPubMed
36.
Zurück zum Zitat Jafarzadeh H, Sanatkhani M, Mohtasham N (2006) Oral pyogenic granuloma: a review. J Oral Sci 48(4):167–175CrossRefPubMed Jafarzadeh H, Sanatkhani M, Mohtasham N (2006) Oral pyogenic granuloma: a review. J Oral Sci 48(4):167–175CrossRefPubMed
37.
Metadaten
Titel
Epulis: a study of 92 cases with special emphasis on histopathological diagnosis and associated clinical data
verfasst von
Astrid Truschnegg
Stephan Acham
Birgit Alexandra Kiefer
Norbert Jakse
Alfred Beham
Publikationsdatum
18.11.2015
Verlag
Springer Berlin Heidelberg
Erschienen in
Clinical Oral Investigations / Ausgabe 7/2016
Print ISSN: 1432-6981
Elektronische ISSN: 1436-3771
DOI
https://doi.org/10.1007/s00784-015-1665-3

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