Introduction
Methods
Patients
Procedures
Statistical analysis
Results
RDN | Sham control | |
---|---|---|
All patients meeting safety escape criteria | 177/103 mmHg (N = 16) | 176/108 mmHg (N = 27) |
Escape due to SBP ≥ 180 mmHg (hypertensive urgency) | 188/102 mmHg (N = 7) | 187/108 mmHg (N = 15) |
Escape due to other safety reason1 | 168/104 mmHg (N = 9) | 161/108 mmHg (N = 12) |
RDN | Sham control | Escape RDN vs. Sham P-value | |||||
---|---|---|---|---|---|---|---|
Escape (N = 16) | Non-Escape (N = 150) | P-value | Escape (N = 28) | Non-Escape (N = 137) | P-value | ||
Age | 53.8 ± 13.6 | 52.3 ± 10.6 | 0.59 | 54.6 ± 10.2 | 52.1 ± 10.4 | 0.26 | 0.83 |
Male | 50.0% (8/16) | 66.0% (99/150) | 0.27 | 75.0% (21/28) | 67.2% (92/137) | 0.51 | 0.11 |
BMI | 30.3 ± 5.0 | 31.2 ± 6.1 | 0.56 | 32.8 ± 5.1 | 30.5 ± 5.5 | 0.038 | 0.12 |
Length of HTN diagnosis | 0.35 | 0.024 | 0.30 | ||||
0–5 years | 43.8% (7/16) | 44.7% (67/150) | 28.6% (8/28) | 48.9% (67/137) | |||
6–10 years | 0.0% (0/16) | 22.0% (33/150) | 10.7% (3/28) | 13.9% (19/137) | |||
> 10 Years | 56.3% (9/16) | 33.3% (50/150) | 60.7% (17/28) | 37.2% (51/137) | |||
Current smoker | 12.5% (2/16) | 17.3% (26/150) | 1.00 | 10.7% (3/28) | 17.5% (24/137) | 0.58 | 1.00 |
Type 2 Diabetes Mellitus | 6.3% (1/16) | 3.3% (5/150) | 0.46 | 17.9% (5/28) | 2.9% (4/137) | 0.008 | 0.39 |
eGFR (ml/min/1.73 m2) | 85.8 ± 19.1 | 85.2 ± 15.7 | 0.88 | 82.3 ± 18.7 | 87.9 ± 16.8 | 0.12 | 0.55 |
RDN | Sham control | Escape RDN vs. Sham P-value | |||||
---|---|---|---|---|---|---|---|
Mean ± SD or % | Escape (N = 16) | Non-Escape (N = 150) | P-value | Escape (N = 28) | Non-Escape (N = 137) | P-value | |
Office SBP (mmHg) | 164 ± 7 | 163 ± 8 | 0.68 | 167 ± 8 | 162 ± 7 | 0.002 | 0.19 |
Office DBP (mmHg) | 102 ± 9 | 101 ± 7 | 0.81 | 103 ± 9 | 102 ± 7 | 0.52 | 0.69 |
24 h SBP (mmHg) | 156 ± 8 | 151 ± 8 | 0.010 | 154 ± 7 | 150 ± 8 | 0.010 | 0.38 |
24 h DBP (mmHg) | 100 ± 10 | 98 ± 7 | 0.29 | 99 ± 10 | 99 ± 7 | 0.92 | 0.74 |