Psoriasis is a chronic systemic disorder primarily affecting the skin [ 1 ]. Multiple forms of psoriasis exist, the most prevalent being psoriasis vulgaris (PV) characterized by erythematous skin plaques with silvery-white scaling [ 2 ]. All forms …
verfasst von:
Jan Gröschel, Leonhard Grassow, Edyta Blaszczyk, Kerstin Lommel, Georgios Kokolakis, Robert Sabat, Jeanette Schulz-Menger
Transcatheter aortic valve implantation (TAVI) has become the standard therapy for many patients with symptomatic aortic stenosis (AS) and high surgical risk [ 1 , 2 ]. Extensive research is being conducted to better understand the prognosis of AS …
Chronic kidney disease (CKD) is increasing worldwide, with an estimated prevalence of 13% [ 1 , 2 ]. Patients with CKD face an elevated risk of heart failure (HF) and those who develop HF have a high risk of HF readmissions, CKD progression, and …
verfasst von:
Flemming Javier Olsen, Nino Emanuel Landler, Jacob Christensen, Bo Feldt-Rasmussen, Ditte Hansen, Christina Christoffersen, Ellen Linnea Freese Ballegaard, Ida Maria Hjelm Sørensen, Sasha Saurbrey Bjergfelt, Eline Seidelin, Susanne Bro, Tor Biering-Sørensen
Approximately 1000–2000 people under 40 years of age die suddenly and unexpectedly per annum in Germany from cardiac causes [ 1 ]. These cases are referred to as sudden cardiac death in the young (SCDY). According to previous studies, a significant …
verfasst von:
Renaldas Barkauskas, Tina Jenewein, Stefanie Scheiper-Welling, Verena Wilmes, Constanze Niess, Silvana Petzel-Witt, Alexandra Reitz, Elise Gradhand, Anastasia Falagkari, Maria Papathanasiou, Reza Wakili, David M. Leistner, Jessica Vasseur, Jens Göbel, Holger Storf, Stefan W. Toennes, Matthias Kettner, Marcel A. Verhoff, Britt-Maria Beckmann, Silke Kauferstein, Eva Corvest
The percutaneous coronary intervention (PCI) has shown great advancement both in terms of safety and efficacy in the contemporary era [ 1 , 2 ]. Notwithstanding this, the number of readmissions for repeat revascularization following index PCI …
verfasst von:
Alp Aytekin, Maria Scalamogna, J. J. Coughlan, Shqipdona Lahu, Gjin Ndrepepa, Maurizio Menichelli, Katharina Mayer, Jochen Wöhrle, Isabell Bernlochner, Bernhard Witzenbichler, Willibald Hochholzer, Dirk Sibbing, Dominick J. Angiolillo, Rayyan Hemetsberger, Ralph Tölg, Christian Valina, Arne Müller, Sebastian Kufner, Christoph Liebetrau, Erion Xhepa, Alexander Hapfelmeier, Hendrik B. Sager, Michael Joner, Gert Richardt, Karl-Ludwig Laugwitz, Franz Josef Neumann, Heribert Schunkert, Stefanie Schüpke, Adnan Kastrati, Salvatore Cassese
Coronary artery disease (CAD) is one of the leading causes of death worldwide. Patients with stable CAD have an increased risk of future cardiovascular (CV) events. Given that the severity of coronary arterial stenosis cannot efficiently predict …
The incidence and prevalence of heart failure (HF) have been growing over the last several decades [ 1 – 6 ]. HF of origin has become increasingly common because of the improved survival of patients with acute myocardial infarction (AMI) [ 1 , 7 …
verfasst von:
Tobias Heer, Uwe Zeymer, Matthias Hochadel, Lutz Frankenstein, Matthias Pauschinger, Rainer Hambrecht, Oliver Bruder, Michael Böhm, Lars S. Maier, Ralf Zahn, Jochen Senges
Metabolic alkalosis (MA) is a very common acid–base disorder and when severe can have significant adverse effects on cell function and contribute to an increase in mortality [ 1 ]. MA is a common complication of heart failure (HF) especially when …
verfasst von:
Joan Carles Trullàs, Ana Isabel Peláez, Julio Blázquez, Anna Sánchez-Biosca, Manuel Lorenzo López-Reborio, Prado Salamanca-Bautista, José María Fernández-Rodríguez, Miguel Ángel Vázquez-Ronda, Melitón Francisco Dávila-Ramos, Humberto Mendoza-Ruiz-De-Zuazu, José Luís Morales-Rull, Jesús Olmedo-Llanes, Pau Llàcer, Alicia Conde-Martel, on behalf of the ALCALOTIC study investigators
Related to improved revascularization techniques and materials, as well as increasing supply with invasive cardiac devices (such as implantable cardioverter defibrillators (ICD) or resynchronization therapies) and cardiac pharmacotherapies …
verfasst von:
Tobias Schupp, Kathrin Weidner, Felix Lau, Jan Forner, Alexander Schmitt, Marielen Reinhardt, Noah Abel, Niklas Ayasse, Thomas Bertsch, Muharrem Akin, Christel Weiß, Ibrahim Akin, Michael Behnes
HFpEF accounts for > 50% of heart failure cases in the United States but until recently did not have clear diagnostic criteria, specifically when it comes to LVEF [ 1 – 4 ]. The prevalence of HFpEF has been validated through many large HF …
verfasst von:
Joseph Ibrahim, Carly Fabrizio, Ahmet Sezer, Floyd Thoma, Brenden Boyle, Suresh R. Mulukutla, Jessica H. Huston, Marc A. Simon, Gavin W. Hickey
After transcatheter aortic valve replacement (TAVR), new onset of conduction abnormalities occurs frequently [ 1 ]. If high grade AV-blockage persists over 24-48 h or new onset of alternating bundle branch occurs after TAVR, permanent pacemaker …
verfasst von:
Johannes Kirchner, Muhammed Gerçek, Vanessa Sciacca, Jan-Christian Reil, Denise Guckel, Max Potratz, Hazem Omran, Kai Friedrichs, Thomas Eitz, Sabine Bleiziffer, Rene Schramm, Guram Imnadze, Christian Sohns, Jan Gummert, Volker Rudolph, Tanja K. Rudolph, Philipp Sommer, Thomas Fink
Patients with signs and symptoms of myocardial ischemia despite unobstructed coronary arteries have puzzled clinical cardiologists over several decades [ 1 ]. Substantial advances in invasive and noninvasive diagnostic assessments and targeted …
verfasst von:
Roman Tremmel, Valeria Martínez Pereyra, Incifer Broders, Elke Schaeffeler, Per Hoffmann, Markus M. Nöthen, Raffi Bekeredjian, Udo Sechtem, Matthias Schwab, Peter Ong
Myocardial infarctions in younger people are considered rare events but occur more frequently than generally assumed. It had been shown in 2015 that 1 in 15 myocardial infarctions affect a patient younger than 45 years; the majority of these are …
verfasst von:
Christoph Altmann, Nelu-Adrian Burlacu, Thomas Preuss, Annett Hlousek, Stephan Eddicks, on behalf of the MEDIAN Medical Board Cardiology
Transcatheter aortic valve implantation (TAVI) for severe aortic stenosis (AS) has evolved since its conception in the beginning of the century [ 1 ]. Transcatheter heart valve (THV) iterations and operator experience drastically and reproducibly …
verfasst von:
Joris F. Ooms, Kristoff Cornelis, Harindra C. Wijeysundera, Bert Vandeloo, Jan Van Der Heyden, Jan Kovac, David Wood, Albert Chan, Joanna Wykyrzykowska, Liesbeth Rosseel, Michael Cunnington, Frank van der Kley, Benno Rensing, Michiel Voskuil, David Hildick-Smith, Nicolas M. Van Mieghem
Within the last decades, the prevalence of heart failure (HF) has steadily increased due to ongoing demographic changes related to an overall ageing population [ 1 , 2 ]. Global estimates have shown that approximately 64 million people are affected …
verfasst von:
Alexander Schmitt, Michael Behnes, Kathrin Weidner, Mohammad Abumayyaleh, Marielen Reinhardt, Noah Abel, Felix Lau, Jan Forner, Mohamed Ayoub, Kambis Mashayekhi, Ibrahim Akin, Tobias Schupp
A growing number of patients diagnosed with pulmonary arterial hypertension (PAH) has features suggestive of concomitant left heart disease (LHD), albeit not clinically overt, nor sufficient to cause an elevation in pulmonary artery wedge pressure …
verfasst von:
Matteo Toma, Giulio Savonitto, Carlo Maria Lombardi, Edoardo Airò, Mauro Driussi, Piero Gentile, Luke Howard, Martina Moschella, Emma Di Poi, Matteo Pagnesi, Simonetta Monti, Valentino Collini, Luciana D’Angelo, Veronica Vecchiato, Alberto Giannoni, Marianna Adamo, Davide Barbisan, Carolina Bauleo, Andrea Garascia, Marco Metra, Gianfranco Sinagra, Francesco Lo Giudice, Davide Stolfo, Pietro Ameri
Catheter ablation is frequently employed as first-line therapy of atrial flutter and atrial fibrillation (AF) and is recommended in current guidelines [ 1 ]. The combination of atrial flutter and/or fibrillation with electrical device therapy for …
verfasst von:
Gerrit Frommeyer, Florian Reinke, Johannes Brachmann, Thorsten Lewalter, Roland Richard Tilz, Stephan Willems, Florian Straube, Ibrahim Akin, Patrick Lugenbiel, Matthias Hochadel, Jochen Senges, Lars Eckardt
The aetiology of heart failure with preserved ejection fraction (HFpEF) is heterogenous and overlaps with that of several comorbidities like atrial fibrillation, diabetes mellitus, chronic kidney disease, valvular heart disease, iron deficiency …
verfasst von:
Stephan von Haehling, Birgit Assmus, Tarek Bekfani, Elke Dworatzek, Frank Edelmann, Djawid Hashemi, Kristian Hellenkamp, Tibor Kempf, Philipp Raake, Katharina A. Schütt, Rolf Wachter, Paul Christian Schulze, Gerd Hasenfuss, Michael Böhm, Johann Bauersachs
Cardiac resynchronization therapy (CRT) is a well-established, effective device therapy for a subgroup of patients who are suffering from heart failure with reduced ejection fraction (HFrEF) and have persistent symptoms of heart failure and wide …
verfasst von:
Richárd Masszi, Előd-János Zsigmond, Réka Ehrenberger, Caner Turan, Péter Fehérvári, Brigitta Teutsch, Zsolt Molnár, Zsófia Drobni, Hajnalka Vágó, Péter Hegyi, Béla Merkely, Annamária Kosztin
