Invasive fungal infections (IFIs) are life-threatening diseases mainly seen in immunocompromised and immunodeficient patients [ 1 , 2 ]. Aspergillus fumigatus ( A. fumigatus ) is the most common IFI pathogen, affecting over 250,000 patients …
verfasst von:
Jianhao Lai, Swati Shah, Neysha Martinez-Orengo, Rekeya Knight, Eyob Alemu, Mitchell L. Turner, Benjamin Wang, Anna Lyndaker, Jianfeng Shi, Falguni Basuli, Dima A. Hammoud
Angiogenesis plays a crucial role in tumor growth, progression, and metastasis by fulfilling the increasing demand for oxygen and nutrients [ 1 ]. Targeting neovascularization has emerged as a promising strategy in cancer diagnosis and treatment [ …
verfasst von:
Biao Yang, Changyu Shan, Xiangming Song, Xiaoying Lv, Yu Long, Dexing Zeng, Rui An, Xiaoli Lan, Yongkang Gai
Nuclear medicine practitioners are faced with the responsibility of communicating imaging examination results to clinicians involved directly in the management of patients referred to them for imaging studies, but do they have a role in …
verfasst von:
Sandra Gonzalez, Frédéric Comte, Jean-Marc Israël, Fabrice Rezungles, Pierre Le Coz, David Taïeb
Neuroendocrine tumours (NETs) constitute a heterogeneous group of rare malignant neoplasms originating from the neuroendocrine cell system [ 1 – 3 ]. The presentation, prognosis, molecular features, clinical behaviour and location of NETs are …
verfasst von:
Secondo Lastoria, Marcello Rodari, Maddalena Sansovini, Sergio Baldari, Antonio D’Agostini, Anna Rita Cervino, Angelina Filice, Matteo Salgarello, Germano Perotti, Alberto Nieri, Davide Campana, Riccardo Emanuele Pellerito, Elena Pomposelli, Valeria Gaudieri, Giovanni Storto, Chiara Maria Grana, Alberto Signore, Giuseppe Boni, Francesco Dondi, Gabriele Simontacchi, Ettore Seregni
Lung cancer is the most common cancer and the leading cause of cancer-related death in both men and women worldwide [ 1 ]. The estimated number of deaths from lung and bronchus cancer in 2021 for both sexes is 131,880, accounting for 21.7% of all …
verfasst von:
Tao Zhang, Xinrui Ma, Muyun Xu, Jinghua Cai, Jianhua Cai, Yanguang Cao, Zhihao Zhang, Xin Ji, Jian He, German Oscar Fonseca Cabrera, Xuedan Wu, Weiling Zhao, Zhanhong Wu, Jin Xie, Zibo Li
Hybrid positron emission tomography (PET)/computed tomography (CT) systems have been accepted as standard-of-care imaging modality in oncology, cardiology and neurology [ 1 , 2 ]. The standardised uptake value (SUV), determined from a static image …
verfasst von:
W. Lan, H. Sari, A. Rominger, C. la Fougère, F. P. Schmidt
Ovarian metastases of signet ring cell cancer (SRCC) are referred to as Krukenberg tumors (KTs) and account for approximately 1–2% of all ovarian cancers [ 1 ]. The stomach is the most common primary site for Krukenberg tumors, followed by the …
verfasst von:
Tingting Wang, Gan Huang, Haitao Zhao, Lianghua Li, Yanying Shen, Weihua Lou, Jianjun Liu
Penile cancer (PeCa) is a rare disease in industrial countries with a worldwide incidence of 0.08/100.000 [ 1 ]. 5-year overall survival is 95% for localized disease and drops to 35–80% in pN + patients [ 2 ]. Patients with ≥ pT1b and cN0 status on …
verfasst von:
Lennert Eismann, Stephan T. Ledderose, Benazir Enzinger, Elena Berg, Thilo Westhofen, Severin Rodler, Gerald B. Schulz, Johannes Toms, Adrien Holzgreve, Franz J. Gildehaus, Matthias Brendel, Clemens C. Cyran, Marcus Unterrainer, Christian G. Stief, Peter Bartenstein, Boris Schlenker, Lena M. Unterrainer
About 1% of the global population suffers from epilepsy [ 1 ], and for approximately 30% of the patients, anti-seizure medication (ASM) does not lead to seizure freedom [ 2 ]. Levetiracetam (LEV) is a very commonly used ASM approved for the …
verfasst von:
Maja R. Marstrand-Joergensen, Gjertrud L. Laurell, Susan Herrmann, Arafat Nasser, Annette Johansen, Anton Lund, Thomas L. Andersen, Gitte M. Knudsen, Lars H. Pinborg
Fibroblasts are the most common component of connective tissues and are found throughout the body [ 1 ]. In normal tissues, they are resting mesenchymal cells in the extracellular matrix (ECM). Normal activated fibroblasts (NAF) aid in repair and …
verfasst von:
Peter George Maliha, Masatoshi Hotta, Andrea Farolfi, Tristan Grogan, Rejah Alano, Andrea Limon, Ethan Lam, Giuseppe Carlucci, Shadfar Bahri, Ali Salavati, Matthias Benz, Daniel Silverman, Pawan Gupta, Andrew Quon, Martin Allen-Auerbach, Johannes Czernin, Jeremie Calais
(endorsed by the ACR, ESSO, ESTRO, EUSOBI/ESR, and EUSOMA)
The aim of this guideline is to provide information regarding the role of 2-[ 18 F]fluoro-2-deoxy- D -glucose positron emission tomography/computed tomography (2-[ 18 F]FDG PET/CT) in patients with no special type breast cancer (NST BC) …
verfasst von:
Sofia C. Vaz, John Patrick Pilkington Woll, Fatima Cardoso, David Groheux, Gary J. R. Cook, Gary A. Ulaner, Heather Jacene, Isabel T. Rubio, Jan W. Schoones, Marie-Jeanne Vrancken Peeters, Philip Poortmans, Ritse M. Mann, Stephanie L. Graff, Elizabeth H. Dibble, Lioe-Fee de Geus-Oei
Gianpaolo Di Santo, Giulia Santo, Vladan Martinovic, Dominik Wolf, Andreas Pircher, Anna Sviridenko, Judith Löffler-Ragg, Elisabeth von Guggenberg, Irene Virgolini
[18F]FDG PET/CT is an established modality of tumour staging. In the multicentre study PETABC, 369 patients with invasive ductal carcinoma and clinical TNM stage III or IIB were randomly assigned to receive either [18F]FDG PET/CT imaging or …
