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Indian Journal of Pediatrics

Erschienen in:

27.10.2023 | Original Article

Efficacy of Teleconsultation-Based Rehabilitation in Children with Landry-Guillain-Barré Syndrome: An Open Label Randomized Controlled Trial (Tele Rehab-LGBS Trial)

verfasst von: Rishitha Pravallika, Renu Suthar, Amol Patil, Manisha Malviya, Somya Saxena, Lokesh Saini, Arun Bansal

Erschienen in: Indian Journal of Pediatrics | Ausgabe 5/2024

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Abstract

Objectives

To evaluate the feasibility and efficacy of teleconsultation-based rehabilitation in children with Landry-Guillain-Barré syndrome (LGBS), measured with Medical Research Council (MRC) sum score and Hughes score.

Methods

A pragmatic, prospective, parallel open label randomized controlled trial was conducted among a total of 50 children with LGBS. The children were randomized using computer generated block randomization into 2 groups (25 in each group): Standard of care (Group A) and teleconsultation-based rehabilitation (Group B). Primary and secondary outcomes were measured with MRC sum score and Hughes score at 12- and 24-wk follow-up.

Results

The mean age was 6.4 ± 3.3 y; 29 (58%) were boys. Baseline MRC sum score (median, IQR), and Hughes score (median, IQR) in group A was 24 (7–31) and 5 (4–5) respectively; and in group B was 18 (9–24) and 4 (4–5) respectively. At discharge, median (IQR) MRC sum score in group A and B was 34 (28–41), and 30 (25–43) (p value = 0.31) respectively. Tele-rehabilitation was provided to group B for 24 wk with 96% compliance. At 12 wk, median MRC sum score in group A and group B were similar [48 (IQR 44–54) vs. 52 (IQR 46–60), p value = 0.08]. At 12 wk and 24 wk, median Hughes score in group A and B were similar. At 24 wk, 15 out of 23 subjects of group A and 18 out of 25 subjects of group B were ambulatory (p value = 0.61).

Conclusions

Teleconsultation-based rehabilitation was feasible with a high compliance rate. The functional outcomes measured with MRC sum score and Hughes score were similar in both the groups at 12 and 24 wk follow-up. Teleconsultation-based rehabilitation has similar efficacy as physical rehabilitation.

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Titel: Efficacy of Teleconsultation-Based Rehabilitation in Children with Landry-Guillain-Barré Syndrome: An Open Label Randomized Controlled Trial (Tele Rehab-LGBS Trial)
verfasst von: Rishitha Pravallika
Renu Suthar
Amol Patil
Manisha Malviya
Somya Saxena
Lokesh Saini
Arun Bansal
Publikationsdatum: 27.10.2023
Verlag: Springer India
Erschienen in: Indian Journal of Pediatrics / Ausgabe 5/2024
Print ISSN: 0019-5456
Elektronische ISSN: 0973-7693
DOI: https://doi.org/10.1007/s12098-023-04882-5

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Efficacy of Teleconsultation-Based Rehabilitation in Children with Landry-Guillain-Barré Syndrome: An Open Label Randomized Controlled Trial (Tele Rehab-LGBS Trial)