Erschienen in:
01.12.2014 | Review
Cardiovascular sequelae of radiation therapy
verfasst von:
Francesco Santoro, Nicola Tarantino, Pier Luigi Pellegrino, Marica Caivano, Agostino Lopizzo, Matteo Di Biase, Natale Daniele Brunetti
Erschienen in:
Clinical Research in Cardiology
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Ausgabe 12/2014
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Abstract
Radiotherapy (RT) is one of the main therapeutic options for malignancy treatment; nevertheless, RT is not free from side effects, including an increased risk for secondary neoplasms and other organs injury. Cardiovascular complications are the second most frequent fatal post-RT sequelae, which physicians should be aware of and ready to diagnose early and cure. This review therefore aims to examine epidemiology, pathogenesis and clinical dose-correlated manifestations of RT-induced cardiovascular disease. Future perspectives on screening, prevention and treatment are also provided.