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Erschienen in:

12.06.2023 | Arzneimitteltherapie bei Älteren | CME

Kardiovaskuläre Pharmakotherapie im Alter

verfasst von: Prof. Dr. Martin Schulz, Dietmar Trenk, Ulrich Laufs

Erschienen in: Herz | Ausgabe 4/2023

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Zusammenfassung

Kardiovaskuläre Erkrankungen stellen die häufigste Ursache für Behinderung und Tod dar. Evidenzbasierte Pharmakotherapie ist die Basis zur erfolgreichen Therapie der Volkskrankheiten Hypertonie, Herzinsuffizienz, koronare Herzkrankheit und Vorhofflimmern. Der Anteil älterer Menschen mit mehreren Krankheiten (Multimorbidität), die 5 oder mehr Arzneimittel täglich benötigen (Polymedikation), nimmt stetig zu. Die Evidenz zur Wirksamkeit und Sicherheit von Arzneimitteln bei diesen Menschen ist begrenzt, da diese häufig von klinischen Studien ausgeschlossen oder unterrepräsentiert sind. Leitlinien fokussieren zudem größtenteils auf einzelne Krankheiten und behandeln nur gelegentlich die Herausforderungen in der Pharmakotherapie älterer multimorbider Patienten mit Multimedikation. Dieser Artikel beschreibt die Chancen und die Besonderheiten der Pharmakotherapie bei Hypertonie, chronischer Herzinsuffizienz und Fettstoffwechselstörungen sowie der antithrombotischen Therapie bei (Hoch‑)Betagten.

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Titel: Kardiovaskuläre Pharmakotherapie im Alter
verfasst von: Prof. Dr. Martin Schulz
Dietmar Trenk
Ulrich Laufs
Publikationsdatum: 12.06.2023
Verlag: Springer Medizin
Schlagwörter: Arzneimitteltherapie bei Älteren
Polymedikation bei geriatrischen Patienten
Herzerkrankungen und Komorbidität
Pharmakokinetik
Pharmakodynamik
Vorhofflimmern
Hypertonie
Herzinsuffizienz
Koronare Herzerkrankung
Orale Antikoagulanzien
Erschienen in: Herz / Ausgabe 4/2023
Print ISSN: 0340-9937
Elektronische ISSN: 1615-6692
DOI: https://doi.org/10.1007/s00059-023-05191-5

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